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The map label for this gene is pntA-2 [H]

Identifier: 50086090

GI number: 50086090

Start: 3006321

End: 3006635

Strand: Reverse

Name: pntA-2 [H]

Synonym: ACIAD3079

Alternate gene names: 50086090

Gene position: 3006635-3006321 (Counterclockwise)

Preceding gene: 50086091

Following gene: 50086089

Centisome position: 83.55

GC content: 43.49

Gene sequence:

>315_bases
ATGGTTGAAACGATTACAATTTTCGTCCTTGCCATCTTCGTAGGTTATTACGTGGTATGGGGGGTAACACCTGCATTACA
TACGCCGCTTATGGCAGTGACCAATGCTTTATCTTCGATCATTATCGTGGGCGCGATGATCCAAACCGTGGGTTTACCCA
TGATTGGTGTGGAAGGTAGCGTAGATTTTCAAACAATTAATGTTGTGAGTGTATTAGGCGCAATTGCGGTGTTCTTGGCC
AGTATTAACATTTTTGGTGGTTTCGCAGTGACTGCGCGCATGCTTGAAATGTTTAAGCCGAAGCAGAAAAAATAA

Upstream 100 bases:

>100_bases
ACAAAAATTTTGCCATCAATCCAGAAGAAGAAATTCAGAAAGCCCTATTGGTCACTCATGGCGGTCAAGTGCTGCTTAAG
CGTGGTTAAGGAGAATACTC

Downstream 100 bases:

>100_bases
GAGGACGAAAACATGGAATTTATTCGAGCGAATGCAGAGTGGTTCTACCTCATTGGTGCTGTCCTGTTTATTATGACGCT
ACGTGGTTTGTCTGGCCCTA

Product: pyridine nucleotide transhydrogenase (proton pump), alpha subunit (part2)

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit alpha 2; Proton-translocating transhydrogenase component 2; Pyridine nucleotide transhydrogenase subunit alpha 2; dII [H]

Number of amino acids: Translated: 104; Mature: 104

Protein sequence:

>104_residues
MVETITIFVLAIFVGYYVVWGVTPALHTPLMAVTNALSSIIIVGAMIQTVGLPMIGVEGSVDFQTINVVSVLGAIAVFLA
SINIFGGFAVTARMLEMFKPKQKK

Sequences:

>Translated_104_residues
MVETITIFVLAIFVGYYVVWGVTPALHTPLMAVTNALSSIIIVGAMIQTVGLPMIGVEGSVDFQTINVVSVLGAIAVFLA
SINIFGGFAVTARMLEMFKPKQKK
>Mature_104_residues
MVETITIFVLAIFVGYYVVWGVTPALHTPLMAVTNALSSIIIVGAMIQTVGLPMIGVEGSVDFQTINVVSVLGAIAVFLA
SINIFGGFAVTARMLEMFKPKQKK

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG3288

COG function: function code C; NAD/NADP transhydrogenase alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI122939155, Length=97, Percent_Identity=50.5154639175258, Blast_Score=86, Evalue=7e-18,
Organism=Homo sapiens, GI122939153, Length=97, Percent_Identity=50.5154639175258, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1787887, Length=94, Percent_Identity=58.5106382978723, Blast_Score=98, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17550456, Length=100, Percent_Identity=46, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 11090; Mature: 11090

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVETITIFVLAIFVGYYVVWGVTPALHTPLMAVTNALSSIIIVGAMIQTVGLPMIGVEGS
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VDFQTINVVSVLGAIAVFLASINIFGGFAVTARMLEMFKPKQKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVETITIFVLAIFVGYYVVWGVTPALHTPLMAVTNALSSIIIVGAMIQTVGLPMIGVEGS
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VDFQTINVVSVLGAIAVFLASINIFGGFAVTARMLEMFKPKQKK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]