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The map label for this gene is rhtB [C]

Identifier: 50086001

GI number: 50086001

Start: 2908938

End: 2909552

Strand: Direct

Name: rhtB [C]

Synonym: ACIAD2980

Alternate gene names: 50086001

Gene position: 2908938-2909552 (Clockwise)

Preceding gene: 50085993

Following gene: 50086007

Centisome position: 80.83

GC content: 46.5

Gene sequence:

>615_bases
TTGCTGACATTTTGGGGTGTTTCCGCGTTGTTTATTTTAACTCCCGGCGCCGATTGGGCTTATGCCATCACAGCGGGGAT
CCGTGGAAGAGTGGTGATTCCTGCTGTGTTTGGACTGCTGCTCGGGCATGCGTTGAGTACACTCCTTGTCGCCACAGGCA
TTGGTGCGATTGTGAATGGTTCACCTCTATTGCTTCAGGTATTAACAGCAGCAGGCGCACTGTATTTACTCTGGCTCGGA
ATCGGCTTACTCAAAAATCCCGTTGAGCTTCGTCATTCTTCCGCGTTACTCACCACCACGAGTCAGACACGGCACTGGTT
GGTTAAAGGTCTGTGCATTAGCGGGTTAAATCCGAAAGTATTTTTATTGTTTTTTGCTTTGCTGCCACAATTTATCGATT
TATCTTCTGGTTTTACTGTTTCAACCCAAATTTTAGTGCTGGGGATGATTCATCTGGCAACATGTAGCGTCATTTATTAT
GCGGTGGGTTTTGGTTCTCATGCACTGCTTAAAACCCGGCCACATGCGGCACAGCGTATCAGCCAAGTTTCGGGTGCATT
GATGATCATCATTGCGAGCTTACTTCTAATCGATCAATCTCATCATTTGGTTTAA

Upstream 100 bases:

>100_bases
TTCTAATCTGTTCTGGCTATGCTTTTCTACATACCGTTACGCTCTTATACGCCCGCTCGTACTTATTCAATTTAGGAAGA
TGACAATGAATATGAATACC

Downstream 100 bases:

>100_bases
ATTGCCTGATATAGAACGCGCCACTCACATACACCATGATCTGATTTAAATGGCCCGAACACATTTGTCAGCAATTAAAA
AAGCGGGCTTAAGCCCGCTT

Product: amino acid efflux transmembrane protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: Lysine Exporter Protein LysE/YggA; Amino Acid Transporter LysE; Amino Acid Efflux Protein; LysE Type Translocator Family Protein; LysE-Family Efflux Protein; Transporter Protein; Amino Acid Efflux Transmembrane Protein; Transporter LysE Family; LysE Family Translocator Protein; LysE Family Efflux Protein; LysE Family Transporter; Threonine Efflux Protein

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MLTFWGVSALFILTPGADWAYAITAGIRGRVVIPAVFGLLLGHALSTLLVATGIGAIVNGSPLLLQVLTAAGALYLLWLG
IGLLKNPVELRHSSALLTTTSQTRHWLVKGLCISGLNPKVFLLFFALLPQFIDLSSGFTVSTQILVLGMIHLATCSVIYY
AVGFGSHALLKTRPHAAQRISQVSGALMIIIASLLLIDQSHHLV

Sequences:

>Translated_204_residues
MLTFWGVSALFILTPGADWAYAITAGIRGRVVIPAVFGLLLGHALSTLLVATGIGAIVNGSPLLLQVLTAAGALYLLWLG
IGLLKNPVELRHSSALLTTTSQTRHWLVKGLCISGLNPKVFLLFFALLPQFIDLSSGFTVSTQILVLGMIHLATCSVIYY
AVGFGSHALLKTRPHAAQRISQVSGALMIIIASLLLIDQSHHLV
>Mature_204_residues
MLTFWGVSALFILTPGADWAYAITAGIRGRVVIPAVFGLLLGHALSTLLVATGIGAIVNGSPLLLQVLTAAGALYLLWLG
IGLLKNPVELRHSSALLTTTSQTRHWLVKGLCISGLNPKVFLLFFALLPQFIDLSSGFTVSTQILVLGMIHLATCSVIYY
AVGFGSHALLKTRPHAAQRISQVSGALMIIIASLLLIDQSHHLV

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 21702; Mature: 21702

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFWGVSALFILTPGADWAYAITAGIRGRVVIPAVFGLLLGHALSTLLVATGIGAIVNG
CCEEECCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
SPLLLQVLTAAGALYLLWLGIGLLKNPVELRHSSALLTTTSQTRHWLVKGLCISGLNPKV
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCHHH
FLLFFALLPQFIDLSSGFTVSTQILVLGMIHLATCSVIYYAVGFGSHALLKTRPHAAQRI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCHHHHHH
SQVSGALMIIIASLLLIDQSHHLV
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLTFWGVSALFILTPGADWAYAITAGIRGRVVIPAVFGLLLGHALSTLLVATGIGAIVNG
CCEEECCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
SPLLLQVLTAAGALYLLWLGIGLLKNPVELRHSSALLTTTSQTRHWLVKGLCISGLNPKV
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEEECHHHHHHHHHHHHHCCCCHHH
FLLFFALLPQFIDLSSGFTVSTQILVLGMIHLATCSVIYYAVGFGSHALLKTRPHAAQRI
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEECCCHHHHHH
SQVSGALMIIIASLLLIDQSHHLV
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA