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The map label for this gene is ampG [H]

Identifier: 50085986

GI number: 50085986

Start: 2892263

End: 2893510

Strand: Reverse

Name: ampG [H]

Synonym: ACIAD2963

Alternate gene names: 50085986

Gene position: 2893510-2892263 (Counterclockwise)

Preceding gene: 50085991

Following gene: 50085985

Centisome position: 80.41

GC content: 42.87

Gene sequence:

>1248_bases
ATGATGTCTCCAGCACGTCTTTACTTGCTTTTATTCTCGCTGTATTGGGCACAGGGTTTACCTGTTGGGTTTATGACGCA
TGCGTTGCCTGTGATTTTAAGAGCGCAAGGGGTATCTCTGGCACATATTGGTGGCTTTGGTTTACTCATGCTGCCTTGGT
CAATCAAGATTTTGTGGGCACCTTGGGTTGATCGCTATGGGGTAAAGCGTCTAGGGCACTATCGTAGCTGGATTTTACTG
ACTCAGTTTTGCAGTATTTTAGGGCTATTCATCCTGTCTTTGTTTCCCATTTCTGCTTTGAGTCAGACAGATTATTTACT
CCTTTTTTTTGTACTTATGTTCTGGATTAATTTTGCAGGGGCGACCCAAGATATTGCAACAGATGCCTTGGCAGTCAATT
TGCTTAAAACAGATCAGCAGCACTGGGGCAATACTTTTCAGGTGGTTGGTTCACGTTTGGGTTTTATTGTTGGAGGTGGG
GTCGTGCTCTGGGCACTGGATGCCTTTACCTGGCAAATGACATTTGGTGGACTGGCTGTATTGGTCTTGCTCAATACCTT
ACCTGTTTTATTACAGCAGCCTCAGCATGATCGGGTAATTGCATCACACACCACGTTTTCCCAGATTTCTATACGCCAAT
ATTTTCATTACTTTACTCAGTCATCGCAATTACGCGCATGGCTATGGGTATTGTTCACTTTTAAAATTGCAGATGGAATG
TCTGGACCTGTCCTTAAACCTTTACTGGTGGACATGGGGTTAAACTTTACCCGGATTGGACTCTATGTCACGATTTTAGG
TGCATTTGCAGCATTGCTAGGCGCAGCCTGTGCAGGATTTTTACTGAAATATTATTCGCGTAGTTTCATGCTTATTGTCT
TTTCTATTCTGAAATTGATCAGTTTGGCGGGATATGTTGCCTTATCTTGGGCTTTTGAGTCGAAGATAATGCTGCATCCT
GTATTGATATATAGCGTCAATGCATTAGAAGATCTGTTTGCTGCAATGCTGTTAGTGGTCATGTTGACTTTAGTGATGCA
ATACAGTCGTGCTGAACGGGCGGGAACTGACTTTACTTTTCAAGTGGCTATCATGGCGACAGTTGGGGGTGGGCTTTATA
CCGTGAGTGGCGTGATAGCAGATCAGTTAGGATATACCACGTATTTAAGTATGGTGATGATGATTGGAATTCTGTGCCTA
ATCCCTATTTTAAAATGGACAGGTCAGTTAGAAAAACAATCGACATAA

Upstream 100 bases:

>100_bases
ATATTAAGCCTTTGAAATCGTTGCTTCATTGGCAGAAATGTTAGTCGTATTTTAAAAAAACAATCATTTTGCCACCAACT
CAACCTAAGGTTTAAAGCAC

Downstream 100 bases:

>100_bases
TTTTATTTGTAGACCAATTAAAGCGTCATTTAGCGAATCTTGAAAAATCATATCAGGTCTAGTCATTTTAAAACCTCACG
TGAGCATCAATTAAAGGCCA

Product: MFS family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MMSPARLYLLLFSLYWAQGLPVGFMTHALPVILRAQGVSLAHIGGFGLLMLPWSIKILWAPWVDRYGVKRLGHYRSWILL
TQFCSILGLFILSLFPISALSQTDYLLLFFVLMFWINFAGATQDIATDALAVNLLKTDQQHWGNTFQVVGSRLGFIVGGG
VVLWALDAFTWQMTFGGLAVLVLLNTLPVLLQQPQHDRVIASHTTFSQISIRQYFHYFTQSSQLRAWLWVLFTFKIADGM
SGPVLKPLLVDMGLNFTRIGLYVTILGAFAALLGAACAGFLLKYYSRSFMLIVFSILKLISLAGYVALSWAFESKIMLHP
VLIYSVNALEDLFAAMLLVVMLTLVMQYSRAERAGTDFTFQVAIMATVGGGLYTVSGVIADQLGYTTYLSMVMMIGILCL
IPILKWTGQLEKQST

Sequences:

>Translated_415_residues
MMSPARLYLLLFSLYWAQGLPVGFMTHALPVILRAQGVSLAHIGGFGLLMLPWSIKILWAPWVDRYGVKRLGHYRSWILL
TQFCSILGLFILSLFPISALSQTDYLLLFFVLMFWINFAGATQDIATDALAVNLLKTDQQHWGNTFQVVGSRLGFIVGGG
VVLWALDAFTWQMTFGGLAVLVLLNTLPVLLQQPQHDRVIASHTTFSQISIRQYFHYFTQSSQLRAWLWVLFTFKIADGM
SGPVLKPLLVDMGLNFTRIGLYVTILGAFAALLGAACAGFLLKYYSRSFMLIVFSILKLISLAGYVALSWAFESKIMLHP
VLIYSVNALEDLFAAMLLVVMLTLVMQYSRAERAGTDFTFQVAIMATVGGGLYTVSGVIADQLGYTTYLSMVMMIGILCL
IPILKWTGQLEKQST
>Mature_415_residues
MMSPARLYLLLFSLYWAQGLPVGFMTHALPVILRAQGVSLAHIGGFGLLMLPWSIKILWAPWVDRYGVKRLGHYRSWILL
TQFCSILGLFILSLFPISALSQTDYLLLFFVLMFWINFAGATQDIATDALAVNLLKTDQQHWGNTFQVVGSRLGFIVGGG
VVLWALDAFTWQMTFGGLAVLVLLNTLPVLLQQPQHDRVIASHTTFSQISIRQYFHYFTQSSQLRAWLWVLFTFKIADGM
SGPVLKPLLVDMGLNFTRIGLYVTILGAFAALLGAACAGFLLKYYSRSFMLIVFSILKLISLAGYVALSWAFESKIMLHP
VLIYSVNALEDLFAAMLLVVMLTLVMQYSRAERAGTDFTFQVAIMATVGGGLYTVSGVIADQLGYTTYLSMVMMIGILCL
IPILKWTGQLEKQST

Specific function: Probably acts as a permease in the beta-lactamase induction system and in peptidoglycan recycling [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Homo sapiens, GI19923957, Length=293, Percent_Identity=30.7167235494881, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI300360496, Length=157, Percent_Identity=33.7579617834395, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4757708, Length=157, Percent_Identity=33.7579617834395, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786636, Length=388, Percent_Identity=27.319587628866, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI193205020, Length=163, Percent_Identity=33.7423312883436, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71996375, Length=163, Percent_Identity=33.7423312883436, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17536531, Length=163, Percent_Identity=33.7423312883436, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17536529, Length=163, Percent_Identity=33.1288343558282, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6319697, Length=166, Percent_Identity=32.5301204819277, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24665528, Length=172, Percent_Identity=35.4651162790698, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24665524, Length=172, Percent_Identity=35.4651162790698, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004752
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46240; Mature: 46240

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSPARLYLLLFSLYWAQGLPVGFMTHALPVILRAQGVSLAHIGGFGLLMLPWSIKILWA
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHEEECCEEEEEEC
PWVDRYGVKRLGHYRSWILLTQFCSILGLFILSLFPISALSQTDYLLLFFVLMFWINFAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
ATQDIATDALAVNLLKTDQQHWGNTFQVVGSRLGFIVGGGVVLWALDAFTWQMTFGGLAV
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LVLLNTLPVLLQQPQHDRVIASHTTFSQISIRQYFHYFTQSSQLRAWLWVLFTFKIADGM
HHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
SGPVLKPLLVDMGLNFTRIGLYVTILGAFAALLGAACAGFLLKYYSRSFMLIVFSILKLI
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SLAGYVALSWAFESKIMLHPVLIYSVNALEDLFAAMLLVVMLTLVMQYSRAERAGTDFTF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
QVAIMATVGGGLYTVSGVIADQLGYTTYLSMVMMIGILCLIPILKWTGQLEKQST
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMSPARLYLLLFSLYWAQGLPVGFMTHALPVILRAQGVSLAHIGGFGLLMLPWSIKILWA
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHEEECCEEEEEEC
PWVDRYGVKRLGHYRSWILLTQFCSILGLFILSLFPISALSQTDYLLLFFVLMFWINFAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
ATQDIATDALAVNLLKTDQQHWGNTFQVVGSRLGFIVGGGVVLWALDAFTWQMTFGGLAV
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LVLLNTLPVLLQQPQHDRVIASHTTFSQISIRQYFHYFTQSSQLRAWLWVLFTFKIADGM
HHHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
SGPVLKPLLVDMGLNFTRIGLYVTILGAFAALLGAACAGFLLKYYSRSFMLIVFSILKLI
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
SLAGYVALSWAFESKIMLHPVLIYSVNALEDLFAAMLLVVMLTLVMQYSRAERAGTDFTF
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
QVAIMATVGGGLYTVSGVIADQLGYTTYLSMVMMIGILCLIPILKWTGQLEKQST
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]