| Definition | Acinetobacter sp. ADP1 chromosome, complete genome. |
|---|---|
| Accession | NC_005966 |
| Length | 3,598,621 |
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The map label for this gene is cysG
Identifier: 50085961
GI number: 50085961
Start: 2862619
End: 2863992
Strand: Reverse
Name: cysG
Synonym: ACIAD2934
Alternate gene names: 50085961
Gene position: 2863992-2862619 (Counterclockwise)
Preceding gene: 161349959
Following gene: 50085960
Centisome position: 79.59
GC content: 45.63
Gene sequence:
>1374_bases GTGGAAATTTTTCCAATTTCTCTTAAGTTGCAGCAGCAACGTTGTCTGATCGTGGGTGGGGGCCATATCGCTTATCGTAA AGCGATCTTGCTGGTCAAAGCGGGTGCAATTCTGGATATTGTTGCGCCTGATATTGATCCCCAGTTGATGTCATTGATTG AACAAAGTGCTGGTACAGCCTATGTAAAGCTTTTTGAAGATCATGATCTGGATCGGGTTTATCGTTTGGTGATTGCTGCC ACAGATAATGCAGATGTGAATAAGCGAGTATTTGAACAGGCAGAGCTGAGAAATCTGTTGGTCAATAGTGTCGATGATAT TCCAAACTGTCGTTTTATGGTGCCTGCGATCATCGATCGTTCGCCGCTATTGATTTCGGTGGCATCCAATGGTGCATCGC CAGTGTTATCACGTCAATTGCGTACTCAGATTGAAACACTGGTTCCGCACGGTATGGGTAAACTGGCTGAGTTTTCTGGA CAGTGGCGTAGTCGAGTAAAAGCCCAAATTACCAATCCAGATGAACGTCGGATTTTTTGGGAGGAGCTGTATGCGAGTCC TCTTAAAGAACAGGTATTTAATGATAATTTAGATATTGCCAACCAAATGATGACTCAATCACTGGCTGAGTGGACTGCAC CCAAAGGTGAAGTCTATCTGGTTGGTGCTGGGCCAGGAGATCCTGAGTTATTGACGCTAAAAGCATTACGTCTAATGCAA CAGGCGGATGTCGTGATTTATGATCGTCTGGTCTCTGCTCCAATTTTAGAACTTTGCCGCCGTGATGCAGAAAAGGTGTA TGTCGGAAAGGCACGTTCTAATCATAGTGTGCCACAAGAGGGCATTAATGCGCTTTTAGTTAAATATGCGCAGGCTGGTA AGCGTGTTTGCCGTTTAAAGGGTGGAGATCCATTCATTTTCGGTCGTGGTGGAGAGGAAATTCAGGAGCTATTTGCTGCT GGCATTCCATTTCAGGTGGTGCCTGGTATTACTGCTGCATCGGGTTGTTCGGCCTATGCAGGAATTCCACTGACCCATCG TGATTATGCGCAAAGCGTTCGTTTCTTGACAGGACATCTCAAAGAAGGTTCTCCAGAGTTGCCTTGGAGTGAACTGGTCT ATGAAAATCAGACGCTGGTACTATATATGGGGCTGGTTGGACTTGAGCATATCTGTCAGCAACTGATTGCTCATGGTCAG CGTCCAGATATGCCAGTGGCGTTGGTGTCGAAAGGTACCACACCTGAGCAAAAGGTCGTGGTGGGAACGCTATCTAATAT TGCGTCTAAAATCGCTGAGTATCAAATTCATGCGCCAACCTTAACCATCATTGGTGAAGTTGTCAGTTTACGTGAGCAGT TACAATGGTTATAA
Upstream 100 bases:
>100_bases CGCCCGTACATGGGTGGTGCAACGTATATCGATTAATTGCATCGATTGTGTGCATGATTTTTGCTTTAACCCACCCAACG TTTTGATCTAGAGGTAGGCT
Downstream 100 bases:
>100_bases AACCAGCTGTTCTCTTATTTTGTAGTTGAGAAAATTTGTGATCCACGTTGTATTGTTTGAGCCTGAAATTCCTGCCAATA CAGGCAATATTATCCGTTTG
Product: multifunctional protein [Includes: uroporphyrin-III C-methyltransferase (Urogen III methylase) (SUMT) (uroporphyrinogen III methylase) (UROM); precorrin-2 oxidase; ferrochelatase ] (siroheme synthase)
Products: NA
Alternate protein names: Uroporphyrinogen-III C-methyltransferase; Urogen III methylase; SUMT; Uroporphyrinogen III methylase; UROM; Precorrin-2 dehydrogenase; Sirohydrochlorin ferrochelatase
Number of amino acids: Translated: 457; Mature: 457
Protein sequence:
>457_residues MEIFPISLKLQQQRCLIVGGGHIAYRKAILLVKAGAILDIVAPDIDPQLMSLIEQSAGTAYVKLFEDHDLDRVYRLVIAA TDNADVNKRVFEQAELRNLLVNSVDDIPNCRFMVPAIIDRSPLLISVASNGASPVLSRQLRTQIETLVPHGMGKLAEFSG QWRSRVKAQITNPDERRIFWEELYASPLKEQVFNDNLDIANQMMTQSLAEWTAPKGEVYLVGAGPGDPELLTLKALRLMQ QADVVIYDRLVSAPILELCRRDAEKVYVGKARSNHSVPQEGINALLVKYAQAGKRVCRLKGGDPFIFGRGGEEIQELFAA GIPFQVVPGITAASGCSAYAGIPLTHRDYAQSVRFLTGHLKEGSPELPWSELVYENQTLVLYMGLVGLEHICQQLIAHGQ RPDMPVALVSKGTTPEQKVVVGTLSNIASKIAEYQIHAPTLTIIGEVVSLREQLQWL
Sequences:
>Translated_457_residues MEIFPISLKLQQQRCLIVGGGHIAYRKAILLVKAGAILDIVAPDIDPQLMSLIEQSAGTAYVKLFEDHDLDRVYRLVIAA TDNADVNKRVFEQAELRNLLVNSVDDIPNCRFMVPAIIDRSPLLISVASNGASPVLSRQLRTQIETLVPHGMGKLAEFSG QWRSRVKAQITNPDERRIFWEELYASPLKEQVFNDNLDIANQMMTQSLAEWTAPKGEVYLVGAGPGDPELLTLKALRLMQ QADVVIYDRLVSAPILELCRRDAEKVYVGKARSNHSVPQEGINALLVKYAQAGKRVCRLKGGDPFIFGRGGEEIQELFAA GIPFQVVPGITAASGCSAYAGIPLTHRDYAQSVRFLTGHLKEGSPELPWSELVYENQTLVLYMGLVGLEHICQQLIAHGQ RPDMPVALVSKGTTPEQKVVVGTLSNIASKIAEYQIHAPTLTIIGEVVSLREQLQWL >Mature_457_residues MEIFPISLKLQQQRCLIVGGGHIAYRKAILLVKAGAILDIVAPDIDPQLMSLIEQSAGTAYVKLFEDHDLDRVYRLVIAA TDNADVNKRVFEQAELRNLLVNSVDDIPNCRFMVPAIIDRSPLLISVASNGASPVLSRQLRTQIETLVPHGMGKLAEFSG QWRSRVKAQITNPDERRIFWEELYASPLKEQVFNDNLDIANQMMTQSLAEWTAPKGEVYLVGAGPGDPELLTLKALRLMQ QADVVIYDRLVSAPILELCRRDAEKVYVGKARSNHSVPQEGINALLVKYAQAGKRVCRLKGGDPFIFGRGGEEIQELFAA GIPFQVVPGITAASGCSAYAGIPLTHRDYAQSVRFLTGHLKEGSPELPWSELVYENQTLVLYMGLVGLEHICQQLIAHGQ RPDMPVALVSKGTTPEQKVVVGTLSNIASKIAEYQIHAPTLTIIGEVVSLREQLQWL
Specific function: Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into si
COG id: COG0007
COG function: function code H; Uroporphyrinogen-III methylase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the precorrin methyltransferase family
Homologues:
Organism=Escherichia coli, GI1789768, Length=458, Percent_Identity=52.1834061135371, Blast_Score=445, Evalue=1e-126, Organism=Saccharomyces cerevisiae, GI6322922, Length=252, Percent_Identity=32.9365079365079, Blast_Score=133, Evalue=7e-32,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): CYSG_ACIAD (Q6F8G6)
Other databases:
- EMBL: CR543861 - RefSeq: YP_047471.1 - HSSP: P25924 - ProteinModelPortal: Q6F8G6 - STRING: Q6F8G6 - GeneID: 2878421 - GenomeReviews: CR543861_GR - KEGG: aci:ACIAD2934 - NMPDR: fig|62977.3.peg.2664 - eggNOG: COG0007 - HOGENOM: HBG730212 - OMA: MCRRDAE - PhylomeDB: Q6F8G6 - ProtClustDB: CLSK2307514 - BioCyc: ASP62977:ACIAD2934-MONOMER - GO: GO:0005488 - HAMAP: MF_01646 - InterPro: IPR000878 - InterPro: IPR014777 - InterPro: IPR014776 - InterPro: IPR006366 - InterPro: IPR016040 - InterPro: IPR019478 - InterPro: IPR006367 - InterPro: IPR003043 - Gene3D: G3DSA:3.40.1010.10 - Gene3D: G3DSA:3.30.950.10 - Gene3D: G3DSA:3.40.50.720 - Gene3D: G3DSA:1.10.8.210 - TIGRFAMs: TIGR01469 - TIGRFAMs: TIGR01470
Pfam domain/function: PF10414 CysG_dimeriser; PF00590 TP_methylase; SSF53790 Cor/por_Metransf
EC number: =2.1.1.107; =1.3.1.76; =4.99.1.4
Molecular weight: Translated: 50432; Mature: 50432
Theoretical pI: Translated: 6.43; Mature: 6.43
Prosite motif: PS00839 SUMT_1; PS00840 SUMT_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MEIFPISLKLQQQRCLIVGGGHIAYRKAILLVKAGAILDIVAPDIDPQLMSLIEQSAGTA CCEEEEEEEECCCCEEEEECCHHHHHHHHHEEECCCEEEEECCCCCHHHHHHHHHCCCCE YVKLFEDHDLDRVYRLVIAATDNADVNKRVFEQAELRNLLVNSVDDIPNCRFMVPAIIDR EEEEECCCCHHHHEEEHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCC SPLLISVASNGASPVLSRQLRTQIETLVPHGMGKLAEFSGQWRSRVKAQITNPDERRIFW CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHH EELYASPLKEQVFNDNLDIANQMMTQSLAEWTAPKGEVYLVGAGPGDPELLTLKALRLMQ HHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHH QADVVIYDRLVSAPILELCRRDAEKVYVGKARSNHSVPQEGINALLVKYAQAGKRVCRLK HCCHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEC GGDPFIFGRGGEEIQELFAAGIPFQVVPGITAASGCSAYAGIPLTHRDYAQSVRFLTGHL CCCEEEECCCHHHHHHHHHCCCCEEECCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHC KEGSPELPWSELVYENQTLVLYMGLVGLEHICQQLIAHGQRPDMPVALVSKGTTPEQKVV CCCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEE VGTLSNIASKIAEYQIHAPTLTIIGEVVSLREQLQWL HHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MEIFPISLKLQQQRCLIVGGGHIAYRKAILLVKAGAILDIVAPDIDPQLMSLIEQSAGTA CCEEEEEEEECCCCEEEEECCHHHHHHHHHEEECCCEEEEECCCCCHHHHHHHHHCCCCE YVKLFEDHDLDRVYRLVIAATDNADVNKRVFEQAELRNLLVNSVDDIPNCRFMVPAIIDR EEEEECCCCHHHHEEEHEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCC SPLLISVASNGASPVLSRQLRTQIETLVPHGMGKLAEFSGQWRSRVKAQITNPDERRIFW CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEECCCCHHHHHHH EELYASPLKEQVFNDNLDIANQMMTQSLAEWTAPKGEVYLVGAGPGDPELLTLKALRLMQ HHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHH QADVVIYDRLVSAPILELCRRDAEKVYVGKARSNHSVPQEGINALLVKYAQAGKRVCRLK HCCHHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEC GGDPFIFGRGGEEIQELFAAGIPFQVVPGITAASGCSAYAGIPLTHRDYAQSVRFLTGHL CCCEEEECCCHHHHHHHHHCCCCEEECCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHC KEGSPELPWSELVYENQTLVLYMGLVGLEHICQQLIAHGQRPDMPVALVSKGTTPEQKVV CCCCCCCCHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHEE VGTLSNIASKIAEYQIHAPTLTIIGEVVSLREQLQWL HHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA