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The map label for this gene is mltF [H]

Identifier: 50085872

GI number: 50085872

Start: 2763954

End: 2765066

Strand: Direct

Name: mltF [H]

Synonym: ACIAD2827

Alternate gene names: 50085872

Gene position: 2763954-2765066 (Clockwise)

Preceding gene: 50085871

Following gene: 50085875

Centisome position: 76.81

GC content: 40.7

Gene sequence:

>1113_bases
ATGCACAGTAGTTCAACTTCTGGGTCGAGGCTTGGCCTAGACAATTTTTTTACTTCTCTCCCATTGAAAGCACTTGTATT
GAGTACTGTTGTGTTTCCGTTTCACAGTATTAATGCGAGCAAAGCCCATCAGTATAACTCGGTGGTCAACAGCAATACCC
TGACTGTCGTTGCAGTTGAATCTCCAACGACAGTTTTTAAAGATGGTGAGTTTATTCATGGTTTTGGCTATGATCTTGCC
AGAAATTATGCGCAAACTTTAAACGTTAAGTTAAAGTTTAAAACGGTTAAAGATAATGCAACTGCATTAAAATGGATTAA
TGAAGGACGAGCAAATTTTGCGATGACAACTGCCGATTTTCATAGTGTTGAAAATAAGCAATTAATTTCATTTTCGGCAA
GTTGTGGTGCGGACACGACGCTCCAACAAAATGGTTTAAATACTGCATTAAATTGGGTGTTTAAATATGCCGATGATCCA
TTAACACAAACGGCAAGTAGCTTTGTCTGTCAGAGTAAGCAGAATGGAGCCACACAACAGTTGGCATCGTTTTACAACCG
AAATGTGGTTAAACCAGAATCATGGGATATTATCCAGCGTGATTTAGGTAAACGTTTACCGGTATACAAGGCAAGTTTTA
AACGAAGTGCCGAGCAATATAATCTTGACTGGCATTTGCTTGCTGCAATTGGCTATCAGGAATCTTATCTCAAGCCAGAT
TCGGTTTCACCTACAGGCGTACGTGGCTTGATGATGCTGACTAACAACACTGCACAGGCGATGGGTGTCAGTAATCGTAA
TGACCCCACTCAAAGTATTCAAGGTGGGGCCAAGTATTATGATTTAATGCTTAAACAGTACGAAGATATTCCCTATCCAG
ATCGGAACTGGTACGCCTTGGTTGCTTATAATATGGGACCAGGTGCTGTTGCACAGATTCAAAAGCGAATTCAGTCTGAA
GGTAAAAATCCAAATCAATGGATCAATCTTTACGACCACTTAAACCGCTACCAGAGTCGTAATGGTCGTTATAAGCAAGC
TGTGCAGTATGTAACGAGTATCCGAGCTTATCTTGAGCATATCAAGACTTCTCCACGCTGGGTTGATGTTTAA

Upstream 100 bases:

>100_bases
CATGACTGCCCATCCTCTTTGGATTTACCAACTTGAAAAGAATTTTGACTGCTCTTAGTCGGAATTTTTTTGGGCGTAAA
TTATCTGTAGCGGAGACAAC

Downstream 100 bases:

>100_bases
AACCAATCAGGCAATACAGATATAAAAAAAGCTTACTGCACATGCGTAAGCTTTCTTTACGTCAATCTATCGTGAATTAA
GCGGTATGCTCGAGTACACG

Product: periplasmic binding protein of transport/transglycosylase

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MHSSSTSGSRLGLDNFFTSLPLKALVLSTVVFPFHSINASKAHQYNSVVNSNTLTVVAVESPTTVFKDGEFIHGFGYDLA
RNYAQTLNVKLKFKTVKDNATALKWINEGRANFAMTTADFHSVENKQLISFSASCGADTTLQQNGLNTALNWVFKYADDP
LTQTASSFVCQSKQNGATQQLASFYNRNVVKPESWDIIQRDLGKRLPVYKASFKRSAEQYNLDWHLLAAIGYQESYLKPD
SVSPTGVRGLMMLTNNTAQAMGVSNRNDPTQSIQGGAKYYDLMLKQYEDIPYPDRNWYALVAYNMGPGAVAQIQKRIQSE
GKNPNQWINLYDHLNRYQSRNGRYKQAVQYVTSIRAYLEHIKTSPRWVDV

Sequences:

>Translated_370_residues
MHSSSTSGSRLGLDNFFTSLPLKALVLSTVVFPFHSINASKAHQYNSVVNSNTLTVVAVESPTTVFKDGEFIHGFGYDLA
RNYAQTLNVKLKFKTVKDNATALKWINEGRANFAMTTADFHSVENKQLISFSASCGADTTLQQNGLNTALNWVFKYADDP
LTQTASSFVCQSKQNGATQQLASFYNRNVVKPESWDIIQRDLGKRLPVYKASFKRSAEQYNLDWHLLAAIGYQESYLKPD
SVSPTGVRGLMMLTNNTAQAMGVSNRNDPTQSIQGGAKYYDLMLKQYEDIPYPDRNWYALVAYNMGPGAVAQIQKRIQSE
GKNPNQWINLYDHLNRYQSRNGRYKQAVQYVTSIRAYLEHIKTSPRWVDV
>Mature_370_residues
MHSSSTSGSRLGLDNFFTSLPLKALVLSTVVFPFHSINASKAHQYNSVVNSNTLTVVAVESPTTVFKDGEFIHGFGYDLA
RNYAQTLNVKLKFKTVKDNATALKWINEGRANFAMTTADFHSVENKQLISFSASCGADTTLQQNGLNTALNWVFKYADDP
LTQTASSFVCQSKQNGATQQLASFYNRNVVKPESWDIIQRDLGKRLPVYKASFKRSAEQYNLDWHLLAAIGYQESYLKPD
SVSPTGVRGLMMLTNNTAQAMGVSNRNDPTQSIQGGAKYYDLMLKQYEDIPYPDRNWYALVAYNMGPGAVAQIQKRIQSE
GKNPNQWINLYDHLNRYQSRNGRYKQAVQYVTSIRAYLEHIKTSPRWVDV

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=282, Percent_Identity=31.5602836879433, Blast_Score=121, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638
- InterPro:   IPR000189 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 41667; Mature: 41667

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSSSTSGSRLGLDNFFTSLPLKALVLSTVVFPFHSINASKAHQYNSVVNSNTLTVVAVE
CCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEC
SPTTVFKDGEFIHGFGYDLARNYAQTLNVKLKFKTVKDNATALKWINEGRANFAMTTADF
CCCEEECCCCEEEECCHHHHHHHHHHEEEEEEEEEECCCCHHHHHHHCCCCCEEEEEHHH
HSVENKQLISFSASCGADTTLQQNGLNTALNWVFKYADDPLTQTASSFVCQSKQNGATQQ
HHCCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHH
LASFYNRNVVKPESWDIIQRDLGKRLPVYKASFKRSAEQYNLDWHLLAAIGYQESYLKPD
HHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHCCCCC
SVSPTGVRGLMMLTNNTAQAMGVSNRNDPTQSIQGGAKYYDLMLKQYEDIPYPDRNWYAL
CCCCCCCEEEEEEECCCHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEE
VAYNMGPGAVAQIQKRIQSEGKNPNQWINLYDHLNRYQSRNGRYKQAVQYVTSIRAYLEH
EEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IKTSPRWVDV
HCCCCCEECC
>Mature Secondary Structure
MHSSSTSGSRLGLDNFFTSLPLKALVLSTVVFPFHSINASKAHQYNSVVNSNTLTVVAVE
CCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEEEC
SPTTVFKDGEFIHGFGYDLARNYAQTLNVKLKFKTVKDNATALKWINEGRANFAMTTADF
CCCEEECCCCEEEECCHHHHHHHHHHEEEEEEEEEECCCCHHHHHHHCCCCCEEEEEHHH
HSVENKQLISFSASCGADTTLQQNGLNTALNWVFKYADDPLTQTASSFVCQSKQNGATQQ
HHCCCCEEEEEECCCCCCCCHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHH
LASFYNRNVVKPESWDIIQRDLGKRLPVYKASFKRSAEQYNLDWHLLAAIGYQESYLKPD
HHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHCCCCC
SVSPTGVRGLMMLTNNTAQAMGVSNRNDPTQSIQGGAKYYDLMLKQYEDIPYPDRNWYAL
CCCCCCCEEEEEEECCCHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEE
VAYNMGPGAVAQIQKRIQSEGKNPNQWINLYDHLNRYQSRNGRYKQAVQYVTSIRAYLEH
EEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IKTSPRWVDV
HCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA