BacMap

Definition	Acinetobacter sp. ADP1 chromosome, complete genome.
Accession	NC_005966
Length	3,598,621

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The map label for this gene is entA [H]

Identifier: 50085830

GI number: 50085830

Start: 2721313

End: 2722098

Strand: Reverse

Name: entA [H]

Synonym: ACIAD2774

Alternate gene names: 50085830

Gene position: 2722098-2721313 (Counterclockwise)

Preceding gene: 50085831

Following gene: 50085829

Centisome position: 75.64

GC content: 39.44

Gene sequence:

>786_bases
ATGACCATGACACAGATCAATTCAGAAGTTTTAGATATAAATCTAGTAAAGAAAATTGCGTGGGTAACTGGTGTTAATCA
GGGCATAGGTGCACAGATCATGCAACAACTGATTGCTCAAAATATTTATGTCGTCGGTTTCGATTTATCTATTCGCAATT
TTATGACAAGTGACCATTACGAAGTTCACCAATGTAATGTCGGTGATTCATCACAGGTTTTTGATCTTTGCCAAAAATTA
TTAAATACGTCACCACCAGATTATTTCATCAATACAGCAGGGGTATTGCATTTAGATGGGCACGATGCATTGCCGATTGA
GGCTTGGAGACAAACTTTTGAAGTGAATACCTTTGCTCCATTTTATTTTTTAAAGAATTTAAGTCCACATTTTCGTAACA
AACGTGAAGGTAGCATTGTCATGGTGTCTTCCAATTCTGCACGTGTACCACGCATTGAGATGGCGGCTTACGGTGCATCC
AAAGCGGCATTAACTAGTTTTAGTAAAACTGTAGCTTTGGAACTTGCTGAATATGGCGTACGGGTGAATATTGTATCGCC
AGGTTCTACAGTGACTCCAATGCTTCGTCAACTTTGGAATGATGCGTCTGGGGAGCAAAAAACGATTCATGGAAATTTGG
CGCAATACAAAGTGGGTATTCCATTGCAGAAAATTGCACTAACACAAGACATTGCCAATGCTGTGATGTTCTTAATTAGT
GACCAAGCCTCGCACATCACTATGCATGATTTAGTGGTTGATGGTGGTGCAACTTTAGGTCAATAA

Upstream 100 bases:

>100_bases
TTTGTTCGCTTTGCAATATGTTCAGAATAACTTGGGTGTTGTCGAAGATGTTGAATGTGTCATTGCTTCATAAGGCTAAG
AATTAACAGCTAACTCGAGG

Downstream 100 bases:

>100_bases
GAAAAGGATAAAATAATGCAATTACAGCAAGAAATTACTGCGAAAATTCATCAAGTGCTTCAAGTTGAAGATGTTCATAT
TCAACCCCAAGATAATTTAA

Product: 2,3-dihydroxybenzoate-2,3-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTMTQINSEVLDINLVKKIAWVTGVNQGIGAQIMQQLIAQNIYVVGFDLSIRNFMTSDHYEVHQCNVGDSSQVFDLCQKL
LNTSPPDYFINTAGVLHLDGHDALPIEAWRQTFEVNTFAPFYFLKNLSPHFRNKREGSIVMVSSNSARVPRIEMAAYGAS
KAALTSFSKTVALELAEYGVRVNIVSPGSTVTPMLRQLWNDASGEQKTIHGNLAQYKVGIPLQKIALTQDIANAVMFLIS
DQASHITMHDLVVDGGATLGQ

Sequences:

>Translated_261_residues
MTMTQINSEVLDINLVKKIAWVTGVNQGIGAQIMQQLIAQNIYVVGFDLSIRNFMTSDHYEVHQCNVGDSSQVFDLCQKL
LNTSPPDYFINTAGVLHLDGHDALPIEAWRQTFEVNTFAPFYFLKNLSPHFRNKREGSIVMVSSNSARVPRIEMAAYGAS
KAALTSFSKTVALELAEYGVRVNIVSPGSTVTPMLRQLWNDASGEQKTIHGNLAQYKVGIPLQKIALTQDIANAVMFLIS
DQASHITMHDLVVDGGATLGQ
>Mature_260_residues
TMTQINSEVLDINLVKKIAWVTGVNQGIGAQIMQQLIAQNIYVVGFDLSIRNFMTSDHYEVHQCNVGDSSQVFDLCQKLL
NTSPPDYFINTAGVLHLDGHDALPIEAWRQTFEVNTFAPFYFLKNLSPHFRNKREGSIVMVSSNSARVPRIEMAAYGASK
AALTSFSKTVALELAEYGVRVNIVSPGSTVTPMLRQLWNDASGEQKTIHGNLAQYKVGIPLQKIALTQDIANAVMFLISD
QASHITMHDLVVDGGATLGQ

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=256, Percent_Identity=29.6875, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI19923817, Length=262, Percent_Identity=27.0992366412214, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=28.8537549407115, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI59889578, Length=155, Percent_Identity=33.5483870967742, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=32.0855614973262, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI126723750, Length=150, Percent_Identity=30.6666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI15277342, Length=267, Percent_Identity=25.4681647940075, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=178, Percent_Identity=25.8426966292135, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI40254992, Length=260, Percent_Identity=28.4615384615385, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=45.8167330677291, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=32.6693227091633, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=27.0588235294118, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=25.968992248062, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=27.1317829457364, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=29.1338582677165, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082160, Length=267, Percent_Identity=25.0936329588015, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=24.4186046511628, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789378, Length=154, Percent_Identity=30.5194805194805, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=31.4741035856574, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=30.4347826086957, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=29.1338582677165, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=28.6274509803922, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=30.0395256916996, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=27.6264591439689, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=170, Percent_Identity=33.5294117647059, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=178, Percent_Identity=32.0224719101124, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=199, Percent_Identity=32.1608040201005, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=178, Percent_Identity=31.4606741573034, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=29.7397769516729, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=177, Percent_Identity=32.7683615819209, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=27.8625954198473, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=26.8199233716475, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=179, Percent_Identity=29.0502793296089, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=181, Percent_Identity=31.4917127071823, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=27.3076923076923, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=29.7709923664122, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=179, Percent_Identity=29.608938547486, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=153, Percent_Identity=30.718954248366, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193210355, Length=217, Percent_Identity=27.6497695852535, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=156, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=180, Percent_Identity=29.4444444444444, Blast_Score=64, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI193207185, Length=128, Percent_Identity=35.9375, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=31.2, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=28.8461538461538, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=29.1828793774319, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=28.8617886178862, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357041, Length=170, Percent_Identity=33.5294117647059, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571526, Length=170, Percent_Identity=35.2941176470588, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=25.296442687747, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24644337, Length=171, Percent_Identity=32.1637426900585, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28574402, Length=186, Percent_Identity=26.8817204301075, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24584744, Length=186, Percent_Identity=26.8817204301075, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR003560
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.28 [H]

Molecular weight: Translated: 28728; Mature: 28597

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTQINSEVLDINLVKKIAWVTGVNQGIGAQIMQQLIAQNIYVVGFDLSIRNFMTSDHY
CCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEEEEHHHHHCCCCC
EVHQCNVGDSSQVFDLCQKLLNTSPPDYFINTAGVLHLDGHDALPIEAWRQTFEVNTFAP
EEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEECCCCCCCHHHHHHHHCCCCCHH
FYFLKNLSPHFRNKREGSIVMVSSNSARVPRIEMAAYGASKAALTSFSKTVALELAEYGV
HHHHHCCCHHHCCCCCCCEEEEECCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHCCE
RVNIVSPGSTVTPMLRQLWNDASGEQKTIHGNLAQYKVGIPLQKIALTQDIANAVMFLIS
EEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHCC
DQASHITMHDLVVDGGATLGQ
CCCCEEEEEHEEEECCCCCCC
>Mature Secondary Structure 
TMTQINSEVLDINLVKKIAWVTGVNQGIGAQIMQQLIAQNIYVVGFDLSIRNFMTSDHY
CCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEEEEEHHHHHCCCCC
EVHQCNVGDSSQVFDLCQKLLNTSPPDYFINTAGVLHLDGHDALPIEAWRQTFEVNTFAP
EEEECCCCCCHHHHHHHHHHHCCCCCCEEEECCCEEEECCCCCCCHHHHHHHHCCCCCHH
FYFLKNLSPHFRNKREGSIVMVSSNSARVPRIEMAAYGASKAALTSFSKTVALELAEYGV
HHHHHCCCHHHCCCCCCCEEEEECCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHCCE
RVNIVSPGSTVTPMLRQLWNDASGEQKTIHGNLAQYKVGIPLQKIALTQDIANAVMFLIS
EEEEECCCCHHHHHHHHHHCCCCCCCEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHCC
DQASHITMHDLVVDGGATLGQ
CCCCEEEEEHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2521622; 2521621; 9278503 [H]