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The map label for this gene is etfB [H]

Identifier: 50085724

GI number: 50085724

Start: 2610574

End: 2611323

Strand: Reverse

Name: etfB [H]

Synonym: ACIAD2655

Alternate gene names: 50085724

Gene position: 2611323-2610574 (Counterclockwise)

Preceding gene: 50085725

Following gene: 50085723

Centisome position: 72.56

GC content: 40.93

Gene sequence:

>750_bases
ATGAAGGCTCTTGTTGCTGTAAAACGTGTGGTTGATGCCAACGTTAAAGTTCGCGTAAAGCCGGACAATAGTGGGGTTGA
CTTAACCAATGTTAAAATGTCAATCAACCCATTTTGTGAAATCGCAGTGGAAGAAGCGGTTCGCTTAAAAGAAAAAGGAA
CAGTATCTGAAATCGTTGTGGTTTCTATCGGTCCTAAAGAAGCACAGGAACAAATCCGTTCCTCAATGGCTCTAGGTGCA
GATCGTGGTATTTTGGTCGAAACTGCGGATGAAATTGGTGCTTTAGAAGTTGCTAAAATTCTAAAAGGGATTGTAGAACA
AGAAAAACCAGAATTGATTCTTCTTGGAAAGCAAGCCATTGACGATGACTCAAATCAAGTCGGTCAAATGCTTGCAGCTT
TATTAGATGCAGGTCAGGGTACTTTTGCTTCTGAAGTTAAAGTAGACGCTGGAAAAGTTCAGGTTACTCGTGAAATTGAC
GGTGGTCTACAAACGGTTGAGCTGACACTTCCTGCCATTATTACCACAGATTTACGTTTGAATGAGCCTCGTTATGCGGC
ACTTCCAAACATTATGAAGGCGCGCAAAAAGCCACTAGATACCAAATCTCCAGCAGATTATGGTGTTGCAACAGGTACAA
AACTTAAAACTGTAAAAGTTGAGCCACCTGCTGATCGTAAAGCTGGCGTACAAGTGAAATCAGTCGATGAACTTGTTGAA
AAATTAAAAAATGAAGCGAAAGTGATCTAA

Upstream 100 bases:

>100_bases
AATGCCAAACACATTGCAAGATAAAGCACCTAAAAAATTTAATTTGAAGCGTTAATATAACTCTTCTGAACATTTACTTG
CTGAAACAGCCGAGGATTAC

Downstream 100 bases:

>100_bases
TACGGAAGGATAAAATCATGAGTATTTTAGTTATCGCTGATCACAACAACCAAACACTTAACGGTGCAACGTTAAATGTT
GTTGCGGCAGCACAAAAAAT

Product: electron transfer flavoprotein beta-subunit

Products: NA

Alternate protein names: Beta-ETF; Electron transfer flavoprotein small subunit; ETFSS [H]

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MKALVAVKRVVDANVKVRVKPDNSGVDLTNVKMSINPFCEIAVEEAVRLKEKGTVSEIVVVSIGPKEAQEQIRSSMALGA
DRGILVETADEIGALEVAKILKGIVEQEKPELILLGKQAIDDDSNQVGQMLAALLDAGQGTFASEVKVDAGKVQVTREID
GGLQTVELTLPAIITTDLRLNEPRYAALPNIMKARKKPLDTKSPADYGVATGTKLKTVKVEPPADRKAGVQVKSVDELVE
KLKNEAKVI

Sequences:

>Translated_249_residues
MKALVAVKRVVDANVKVRVKPDNSGVDLTNVKMSINPFCEIAVEEAVRLKEKGTVSEIVVVSIGPKEAQEQIRSSMALGA
DRGILVETADEIGALEVAKILKGIVEQEKPELILLGKQAIDDDSNQVGQMLAALLDAGQGTFASEVKVDAGKVQVTREID
GGLQTVELTLPAIITTDLRLNEPRYAALPNIMKARKKPLDTKSPADYGVATGTKLKTVKVEPPADRKAGVQVKSVDELVE
KLKNEAKVI
>Mature_249_residues
MKALVAVKRVVDANVKVRVKPDNSGVDLTNVKMSINPFCEIAVEEAVRLKEKGTVSEIVVVSIGPKEAQEQIRSSMALGA
DRGILVETADEIGALEVAKILKGIVEQEKPELILLGKQAIDDDSNQVGQMLAALLDAGQGTFASEVKVDAGKVQVTREID
GGLQTVELTLPAIITTDLRLNEPRYAALPNIMKARKKPLDTKSPADYGVATGTKLKTVKVEPPADRKAGVQVKSVDELVE
KLKNEAKVI

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2086

COG function: function code C; Electron transfer flavoprotein, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF beta-subunit/fixA family [H]

Homologues:

Organism=Homo sapiens, GI4503609, Length=252, Percent_Identity=57.1428571428571, Blast_Score=286, Evalue=8e-78,
Organism=Homo sapiens, GI62420877, Length=237, Percent_Identity=56.5400843881857, Blast_Score=267, Evalue=6e-72,
Organism=Caenorhabditis elegans, GI25141345, Length=253, Percent_Identity=51.7786561264822, Blast_Score=227, Evalue=5e-60,
Organism=Saccharomyces cerevisiae, GI6321646, Length=250, Percent_Identity=48.8, Blast_Score=214, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24651147, Length=247, Percent_Identity=53.8461538461538, Blast_Score=235, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24651145, Length=247, Percent_Identity=53.8461538461538, Blast_Score=235, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000049
- InterPro:   IPR014730
- InterPro:   IPR012255
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF [H]

EC number: NA

Molecular weight: Translated: 26696; Mature: 26696

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01065 ETF_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVAVKRVVDANVKVRVKPDNSGVDLTNVKMSINPFCEIAVEEAVRLKEKGTVSEIVV
CHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEE
VSIGPKEAQEQIRSSMALGADRGILVETADEIGALEVAKILKGIVEQEKPELILLGKQAI
EEECCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHC
DDDSNQVGQMLAALLDAGQGTFASEVKVDAGKVQVTREIDGGLQTVELTLPAIITTDLRL
CCCHHHHHHHHHHHHHCCCCCCHHHEEECCCEEEEEEECCCCEEEEEEEECEEEEECEEE
NEPRYAALPNIMKARKKPLDTKSPADYGVATGTKLKTVKVEPPADRKAGVQVKSVDELVE
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHCCEEHHHHHHHH
KLKNEAKVI
HHHHHCCCC
>Mature Secondary Structure
MKALVAVKRVVDANVKVRVKPDNSGVDLTNVKMSINPFCEIAVEEAVRLKEKGTVSEIVV
CHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEE
VSIGPKEAQEQIRSSMALGADRGILVETADEIGALEVAKILKGIVEQEKPELILLGKQAI
EEECCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHC
DDDSNQVGQMLAALLDAGQGTFASEVKVDAGKVQVTREIDGGLQTVELTLPAIITTDLRL
CCCHHHHHHHHHHHHHCCCCCCHHHEEECCCEEEEEEECCCCEEEEEEEECEEEEECEEE
NEPRYAALPNIMKARKKPLDTKSPADYGVATGTKLKTVKVEPPADRKAGVQVKSVDELVE
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHCCEEHHHHHHHH
KLKNEAKVI
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]