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The map label for this gene is lpxP [H]

Identifier: 50085708

GI number: 50085708

Start: 2591163

End: 2592176

Strand: Direct

Name: lpxP [H]

Synonym: ACIAD2638

Alternate gene names: 50085708

Gene position: 2591163-2592176 (Clockwise)

Preceding gene: 50085705

Following gene: 50085715

Centisome position: 72.0

GC content: 39.84

Gene sequence:

>1014_bases
ATGACGACATCTGATTCACGCAGCTTTATGTATCGTTTGCTTAAGTTTATTAGCCGACAACCTATTCAGCTTTCACGTTT
ATTTGCACGTATGCTTGCAGGCTTGGTGAATACGCTCAAACTCACAAAAACATCCAGAACAATTCAACTTAATCTTAAAA
TTACGCTGCCCTATCTAAATGACCAACAACGAGAACGTATTATCCAAAATGCGATTCGTAACGAACTCACCTCTTACATG
GAGTTTTTCAGTATCTGGGGTTCATCCAATCAAAAGAATATCTCTCGCATTCATCATGTAGAAGGTGCAGATTTTTTTCA
TCAGGCTATTGCCGAAAATAAAGGTATCGTTCTCATTGTTCCACATTTTGGAACATGGGAAATCATGAATGCTTGGTGCG
CTCAATATACCGACATGACAATTTTGTATAAACCTGTCAAAGATAAAGATGCCGATCGTTTTGTACGTGAAGCAAGAAGC
CGAGAGCAGGCTAAACTGGTTCCAACAGATGAAAGTGGCGTTCGTCAGATTTTTAAGGCGCTTAAGCAAGGTGGAACCAC
CGTGATCTTGCCTGATCATACCCCGAATGTAGGCGGTGAAATGGTTGATTATTTTGGCATTCCCCTCGCATCAAGTAATC
TCAGCGCTAAATTGATTCAAAAAACCAAGGCAAAAGCTCTTTTTTTATATGCTATTCGCAATGAAAATCATGGTTTTGAT
ATGTTTATTGAACCCATGGATCCTGCGATTTATCAAGGTACAGATCATGATGGCACACTGGTGATTCATCATGCCATTGA
AGACCTCATCAGAAAATATCCAGATCATTACCACTGGAGTTATAAACGTTTCAAAGCCAATCCTGAACTAGATAATCTAT
ACACGCTCAATGAAGAAGATGCTTTAGCCAATGTAGAACAGGTACGTCAAGCCAACAGAGAGCGTCTTAACGCTGCAACC
ACTTATACGACTGACGATAAAATTCTGTCTGCTCATTCCCTGAATCAAACTTAA

Upstream 100 bases:

>100_bases
TTATATACACTGAATCGGTAAAAACTGTTTAATCGTTATAATTTAACTTATAATATTTTTATCCGATAAGCCCCTGTTCT
TGATTCTAAGCACTTTTATA

Downstream 100 bases:

>100_bases
AATGAATCGCTCCCTTATCAGTTGTACTCAATAAGGGAATATTCAAATCTTGCAGACGATTGCTTACCTCAGCACTCGGA
TGACCATATCCATTTTCAAA

Product: lipid A biosynthesis lauroyl acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTTSDSRSFMYRLLKFISRQPIQLSRLFARMLAGLVNTLKLTKTSRTIQLNLKITLPYLNDQQRERIIQNAIRNELTSYM
EFFSIWGSSNQKNISRIHHVEGADFFHQAIAENKGIVLIVPHFGTWEIMNAWCAQYTDMTILYKPVKDKDADRFVREARS
REQAKLVPTDESGVRQIFKALKQGGTTVILPDHTPNVGGEMVDYFGIPLASSNLSAKLIQKTKAKALFLYAIRNENHGFD
MFIEPMDPAIYQGTDHDGTLVIHHAIEDLIRKYPDHYHWSYKRFKANPELDNLYTLNEEDALANVEQVRQANRERLNAAT
TYTTDDKILSAHSLNQT

Sequences:

>Translated_337_residues
MTTSDSRSFMYRLLKFISRQPIQLSRLFARMLAGLVNTLKLTKTSRTIQLNLKITLPYLNDQQRERIIQNAIRNELTSYM
EFFSIWGSSNQKNISRIHHVEGADFFHQAIAENKGIVLIVPHFGTWEIMNAWCAQYTDMTILYKPVKDKDADRFVREARS
REQAKLVPTDESGVRQIFKALKQGGTTVILPDHTPNVGGEMVDYFGIPLASSNLSAKLIQKTKAKALFLYAIRNENHGFD
MFIEPMDPAIYQGTDHDGTLVIHHAIEDLIRKYPDHYHWSYKRFKANPELDNLYTLNEEDALANVEQVRQANRERLNAAT
TYTTDDKILSAHSLNQT
>Mature_336_residues
TTSDSRSFMYRLLKFISRQPIQLSRLFARMLAGLVNTLKLTKTSRTIQLNLKITLPYLNDQQRERIIQNAIRNELTSYME
FFSIWGSSNQKNISRIHHVEGADFFHQAIAENKGIVLIVPHFGTWEIMNAWCAQYTDMTILYKPVKDKDADRFVREARSR
EQAKLVPTDESGVRQIFKALKQGGTTVILPDHTPNVGGEMVDYFGIPLASSNLSAKLIQKTKAKALFLYAIRNENHGFDM
FIEPMDPAIYQGTDHDGTLVIHHAIEDLIRKYPDHYHWSYKRFKANPELDNLYTLNEEDALANVEQVRQANRERLNAATT
YTTDDKILSAHSLNQT

Specific function: Unknown

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI87082094, Length=241, Percent_Identity=22.8215767634855, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787292, Length=252, Percent_Identity=20.2380952380952, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011920 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 38796; Mature: 38665

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSDSRSFMYRLLKFISRQPIQLSRLFARMLAGLVNTLKLTKTSRTIQLNLKITLPYLN
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCEEEEEEEEEEECCCC
DQQRERIIQNAIRNELTSYMEFFSIWGSSNQKNISRIHHVEGADFFHQAIAENKGIVLIV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEE
PHFGTWEIMNAWCAQYTDMTILYKPVKDKDADRFVREARSREQAKLVPTDESGVRQIFKA
CCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCEECCCCHHHHHHHHHH
LKQGGTTVILPDHTPNVGGEMVDYFGIPLASSNLSAKLIQKTKAKALFLYAIRNENHGFD
HHCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCE
MFIEPMDPAIYQGTDHDGTLVIHHAIEDLIRKYPDHYHWSYKRFKANPELDNLYTLNEED
EEEECCCCHHCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCHHEEECCCCCCCEEECCCHH
ALANVEQVRQANRERLNAATTYTTDDKILSAHSLNQT
HHHHHHHHHHHHHHHHCHHEEECCCCHHHCCCCCCCC
>Mature Secondary Structure 
TTSDSRSFMYRLLKFISRQPIQLSRLFARMLAGLVNTLKLTKTSRTIQLNLKITLPYLN
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCEEEEEEEEEEECCCC
DQQRERIIQNAIRNELTSYMEFFSIWGSSNQKNISRIHHVEGADFFHQAIAENKGIVLIV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEE
PHFGTWEIMNAWCAQYTDMTILYKPVKDKDADRFVREARSREQAKLVPTDESGVRQIFKA
CCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCCCCEECCCCHHHHHHHHHH
LKQGGTTVILPDHTPNVGGEMVDYFGIPLASSNLSAKLIQKTKAKALFLYAIRNENHGFD
HHCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCCE
MFIEPMDPAIYQGTDHDGTLVIHHAIEDLIRKYPDHYHWSYKRFKANPELDNLYTLNEED
EEEECCCCHHCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCHHEEECCCCCCCEEECCCHH
ALANVEQVRQANRERLNAATTYTTDDKILSAHSLNQT
HHHHHHHHHHHHHHHHCHHEEECCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]