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The map label for this gene is fbp

Identifier: 50085695

GI number: 50085695

Start: 2577714

End: 2578685

Strand: Direct

Name: fbp

Synonym: ACIAD2625

Alternate gene names: 50085695

Gene position: 2577714-2578685 (Clockwise)

Preceding gene: 50085693

Following gene: 50085696

Centisome position: 71.63

GC content: 39.09

Gene sequence:

>972_bases
ATGTCAAATCTCACCTTGGCTCAATATCTACAACAAAAAAATGGGAATTTGACACCTGAGTTAGCACAAGTAATTGAAAC
GATTGCTAATTCATGTAAAAAAATCGATCATGCCATTCAAAAAGGAGCATTGGCAGATCTGCTTGGAAGCGCAGGCAATG
AAAATGTTCAAGGTGAAACACAGAAAAAACTTGATGTTCTTTCAAATGATTTTCTGATCGATGCGTTGAAAGTTCATCCA
CACGTTGGCGGTTTAGCTTCTGAAGAGTTGGATGAATTTACACCTGGCCAACAAGATGGCAAATACCTCGTATTATTTGA
TCCACTTGATGGTTCAAGTAACATCGATATCAATATGTGTGTAGGTACTATTTTTTCAATTTTACCTGCAAAAAACAGTA
TTACCCAAACCCAAGATTTCATGCAAGCTGGGACTGAACAAGTCGCTGCTGGCTATGTATTGTATGGTCCATCTACCATG
ATGGCGCTTACCTGTGGTGAAGGTGTCGCATTTTTTACCTTTGATCCTGAAAGCCAAACATTTATCTTGACCTCAGATGC
AATTCAGCTTGATGCAGATACTCAAGAATTTGCAATTAATGCTTCAAATCAGCGCCATTGGGAAGAACCAGTAAAACGCT
ATATAGATGAATTACTAGCAGGTAAAACATCCGTTCGCGGCAAAGATTTTAATATGCGCTGGGTAGCATGTATGGTGGCA
GATATTCACCGTATTTTATGCCGTTCTGGCATTTTTATGTATCCTTATGATTTAAAAGATCCAAGTAAAGCAGGTCGTTT
ACGCTTGATGTATGAAGCAAATCCTATGAGTTTTCTTATTGAACAAGCTGGGGGTTCTGCAACAACAGGTCGGGTTCGTA
TTATGGACATTCAACCCAATGATCTACACCAACGGGTTCCTGTGATTATTGGATCAAAAAATGAAGTCGATCTAGTCACC
AGTTACCACTAA

Upstream 100 bases:

>100_bases
CCGTAAATAAAGTAAGATAATTTTTCTTTTTGTCCAATCTCATCTAAACTATAGCGCAGTTGGGGATCACCACCTTTATT
CTTCTTCGGAGTTATTTTGT

Downstream 100 bases:

>100_bases
TAAACCATCAAACTGTGATGCCGACTCTCTGGCATCACAGTGGACGCCATTTATGTCAATTATTTATCTTGAATCTAAAG
ATAACGCCAAAATCAAACAC

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSNLTLAQYLQQKNGNLTPELAQVIETIANSCKKIDHAIQKGALADLLGSAGNENVQGETQKKLDVLSNDFLIDALKVHP
HVGGLASEELDEFTPGQQDGKYLVLFDPLDGSSNIDINMCVGTIFSILPAKNSITQTQDFMQAGTEQVAAGYVLYGPSTM
MALTCGEGVAFFTFDPESQTFILTSDAIQLDADTQEFAINASNQRHWEEPVKRYIDELLAGKTSVRGKDFNMRWVACMVA
DIHRILCRSGIFMYPYDLKDPSKAGRLRLMYEANPMSFLIEQAGGSATTGRVRIMDIQPNDLHQRVPVIIGSKNEVDLVT
SYH

Sequences:

>Translated_323_residues
MSNLTLAQYLQQKNGNLTPELAQVIETIANSCKKIDHAIQKGALADLLGSAGNENVQGETQKKLDVLSNDFLIDALKVHP
HVGGLASEELDEFTPGQQDGKYLVLFDPLDGSSNIDINMCVGTIFSILPAKNSITQTQDFMQAGTEQVAAGYVLYGPSTM
MALTCGEGVAFFTFDPESQTFILTSDAIQLDADTQEFAINASNQRHWEEPVKRYIDELLAGKTSVRGKDFNMRWVACMVA
DIHRILCRSGIFMYPYDLKDPSKAGRLRLMYEANPMSFLIEQAGGSATTGRVRIMDIQPNDLHQRVPVIIGSKNEVDLVT
SYH
>Mature_322_residues
SNLTLAQYLQQKNGNLTPELAQVIETIANSCKKIDHAIQKGALADLLGSAGNENVQGETQKKLDVLSNDFLIDALKVHPH
VGGLASEELDEFTPGQQDGKYLVLFDPLDGSSNIDINMCVGTIFSILPAKNSITQTQDFMQAGTEQVAAGYVLYGPSTMM
ALTCGEGVAFFTFDPESQTFILTSDAIQLDADTQEFAINASNQRHWEEPVKRYIDELLAGKTSVRGKDFNMRWVACMVAD
IHRILCRSGIFMYPYDLKDPSKAGRLRLMYEANPMSFLIEQAGGSATTGRVRIMDIQPNDLHQRVPVIIGSKNEVDLVTS
YH

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI22907028, Length=319, Percent_Identity=39.8119122257053, Blast_Score=228, Evalue=6e-60,
Organism=Homo sapiens, GI189083692, Length=317, Percent_Identity=40.0630914826498, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI16579888, Length=317, Percent_Identity=40.0630914826498, Blast_Score=226, Evalue=3e-59,
Organism=Escherichia coli, GI1790679, Length=327, Percent_Identity=42.5076452599388, Blast_Score=252, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17508131, Length=329, Percent_Identity=43.7689969604863, Blast_Score=254, Evalue=5e-68,
Organism=Saccharomyces cerevisiae, GI6323409, Length=322, Percent_Identity=37.5776397515528, Blast_Score=216, Evalue=4e-57,
Organism=Drosophila melanogaster, GI45550998, Length=325, Percent_Identity=40.9230769230769, Blast_Score=234, Evalue=6e-62,
Organism=Drosophila melanogaster, GI19921562, Length=325, Percent_Identity=40.9230769230769, Blast_Score=234, Evalue=8e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_ACIAD (Q6F982)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047205.1
- HSSP:   P46275
- ProteinModelPortal:   Q6F982
- SMR:   Q6F982
- STRING:   Q6F982
- GeneID:   2878536
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2625
- NMPDR:   fig|62977.3.peg.2398
- eggNOG:   COG0158
- HOGENOM:   HBG731261
- OMA:   YSINEGS
- PhylomeDB:   Q6F982
- ProtClustDB:   PRK09293
- BioCyc:   ASP62977:ACIAD2625-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- PANTHER:   PTHR11556
- PRINTS:   PR00115

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 35586; Mature: 35455

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00124 FBPASE; PS00659 GLYCOSYL_HYDROL_F5

Important sites: BINDING 200-200

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLTLAQYLQQKNGNLTPELAQVIETIANSCKKIDHAIQKGALADLLGSAGNENVQGET
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
QKKLDVLSNDFLIDALKVHPHVGGLASEELDEFTPGQQDGKYLVLFDPLDGSSNIDINMC
HHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEHHH
VGTIFSILPAKNSITQTQDFMQAGTEQVAAGYVLYGPSTMMALTCGEGVAFFTFDPESQT
HHHHHHHHCCCCCHHHHHHHHHHCHHHHHCCEEEECCCEEEEEEECCCEEEEEECCCCCE
FILTSDAIQLDADTQEFAINASNQRHWEEPVKRYIDELLAGKTSVRGKDFNMRWVACMVA
EEEECCCEEECCCCHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
DIHRILCRSGIFMYPYDLKDPSKAGRLRLMYEANPMSFLIEQAGGSATTGRVRIMDIQPN
HHHHHHHHCCCEEEECCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCEEEEEECCCC
DLHQRVPVIIGSKNEVDLVTSYH
CHHCCCCEEEECCCCEEEEEECC
>Mature Secondary Structure 
SNLTLAQYLQQKNGNLTPELAQVIETIANSCKKIDHAIQKGALADLLGSAGNENVQGET
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
QKKLDVLSNDFLIDALKVHPHVGGLASEELDEFTPGQQDGKYLVLFDPLDGSSNIDINMC
HHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHCCCCCCCCCEEEEEECCCCCCCCEEHHH
VGTIFSILPAKNSITQTQDFMQAGTEQVAAGYVLYGPSTMMALTCGEGVAFFTFDPESQT
HHHHHHHHCCCCCHHHHHHHHHHCHHHHHCCEEEECCCEEEEEEECCCEEEEEECCCCCE
FILTSDAIQLDADTQEFAINASNQRHWEEPVKRYIDELLAGKTSVRGKDFNMRWVACMVA
EEEECCCEEECCCCHHEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
DIHRILCRSGIFMYPYDLKDPSKAGRLRLMYEANPMSFLIEQAGGSATTGRVRIMDIQPN
HHHHHHHHCCCEEEECCCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCCCEEEEEECCCC
DLHQRVPVIIGSKNEVDLVTSYH
CHHCCCCEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA