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The map label for this gene is ruvA [H]

Identifier: 50085685

GI number: 50085685

Start: 2569766

End: 2570380

Strand: Direct

Name: ruvA [H]

Synonym: ACIAD2614

Alternate gene names: 50085685

Gene position: 2569766-2570380 (Clockwise)

Preceding gene: 50085684

Following gene: 50085686

Centisome position: 71.41

GC content: 40.81

Gene sequence:

>615_bases
TTGAATCGCATGATTGGTTGTTTAATTGGTGAAGTATTTGCGCTAGAAGCTCCCACTGTTCTGCTGAATGTGAATGGTGT
CGGTTATGAAATTGATACTCCATTATCTACATTTTGCCAATTACAAAAAGGTCAGCATGTTACCCTGTGGACACATCTTG
TGGTACGTGAAGATGCTCAACAATTGTATGGTTTCATCGATGCACAAGAAAAGCTGATTTTCAGAACATTACTTAAGGTA
AACGGCGTTGGCCCTAAAATGGCACTCGGTATTTTATCAACACTTAGTATCGAATTATTCATCCATACCATCGAACATGA
TGATATTAACACCCTGATTAAAGTTCCTGGTGTAGGACGAAAAACAGCCGAACGCTTAATGATTGAGCTGCGTGATCGCT
TCAAGGCTTTGTCTGTACAAGCAACAACAGGTTCAACTGTAACATCTGCCCAAATCCAGTTTAGTTCAAACTCTCCTATT
GCAGAAGCAGAAGCCGCTTTGCAATCTTTGGGTTACAAGCCGATTGAAGCGCAAAAAGCAATTGCAGCTGTCAAAGCTGA
CTATACAGAAGCCGCAGATTTAATTCGCGCAGCTTTAAAATCGATGATGAAGTGA

Upstream 100 bases:

>100_bases
TTTCAATTGCTAGATTAAATGAGTTGCTTGTACAACAGCCGGTTGTCTGATGTGAAGTATCAAGATTTTTGTTATTGTAT
TTTTTGAATTTGAAGAGTGA

Downstream 100 bases:

>100_bases
GTCTATTATGCATGATCGTCTAATTAGCGGAACAGAAAAGCCAGAAGATCATTTTGATCGGGCGATTCGTCCGACCTCAT
TGGCAGACTACATTGGCCAG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MNRMIGCLIGEVFALEAPTVLLNVNGVGYEIDTPLSTFCQLQKGQHVTLWTHLVVREDAQQLYGFIDAQEKLIFRTLLKV
NGVGPKMALGILSTLSIELFIHTIEHDDINTLIKVPGVGRKTAERLMIELRDRFKALSVQATTGSTVTSAQIQFSSNSPI
AEAEAALQSLGYKPIEAQKAIAAVKADYTEAADLIRAALKSMMK

Sequences:

>Translated_204_residues
MNRMIGCLIGEVFALEAPTVLLNVNGVGYEIDTPLSTFCQLQKGQHVTLWTHLVVREDAQQLYGFIDAQEKLIFRTLLKV
NGVGPKMALGILSTLSIELFIHTIEHDDINTLIKVPGVGRKTAERLMIELRDRFKALSVQATTGSTVTSAQIQFSSNSPI
AEAEAALQSLGYKPIEAQKAIAAVKADYTEAADLIRAALKSMMK
>Mature_204_residues
MNRMIGCLIGEVFALEAPTVLLNVNGVGYEIDTPLSTFCQLQKGQHVTLWTHLVVREDAQQLYGFIDAQEKLIFRTLLKV
NGVGPKMALGILSTLSIELFIHTIEHDDINTLIKVPGVGRKTAERLMIELRDRFKALSVQATTGSTVTSAQIQFSSNSPI
AEAEAALQSLGYKPIEAQKAIAAVKADYTEAADLIRAALKSMMK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=42.8571428571429, Blast_Score=173, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22300; Mature: 22300

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRMIGCLIGEVFALEAPTVLLNVNGVGYEIDTPLSTFCQLQKGQHVTLWTHLVVREDAQ
CCCHHHHHHHHHHHCCCCEEEEEECCCCEEECCCHHHHHHHHCCCEEEEHHHHHHHHHHH
QLYGFIDAQEKLIFRTLLKVNGVGPKMALGILSTLSIELFIHTIEHDDINTLIKVPGVGR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEEEEECCCCCCCEEECCCCCH
KTAERLMIELRDRFKALSVQATTGSTVTSAQIQFSSNSPIAEAEAALQSLGYKPIEAQKA
HHHHHHHHHHHHHHHHEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHH
IAAVKADYTEAADLIRAALKSMMK
HHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRMIGCLIGEVFALEAPTVLLNVNGVGYEIDTPLSTFCQLQKGQHVTLWTHLVVREDAQ
CCCHHHHHHHHHHHCCCCEEEEEECCCCEEECCCHHHHHHHHCCCEEEEHHHHHHHHHHH
QLYGFIDAQEKLIFRTLLKVNGVGPKMALGILSTLSIELFIHTIEHDDINTLIKVPGVGR
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEEEEECCCCCCCEEECCCCCH
KTAERLMIELRDRFKALSVQATTGSTVTSAQIQFSSNSPIAEAEAALQSLGYKPIEAQKA
HHHHHHHHHHHHHHHHEEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCCCHHHHH
IAAVKADYTEAADLIRAALKSMMK
HHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA