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The map label for this gene is ruvB

Identifier: 50085686

GI number: 50085686

Start: 2570388

End: 2571392

Strand: Direct

Name: ruvB

Synonym: ACIAD2615

Alternate gene names: 50085686

Gene position: 2570388-2571392 (Clockwise)

Preceding gene: 50085685

Following gene: 50085687

Centisome position: 71.43

GC content: 48.36

Gene sequence:

>1005_bases
ATGCATGATCGTCTAATTAGCGGAACAGAAAAGCCAGAAGATCATTTTGATCGGGCGATTCGTCCGACCTCATTGGCAGA
CTACATTGGCCAGCCTGTAGTACGTGAGCAAATGGAGATCTTTATTGGTGCGGCACGTGGTCGTGGTGAAGCGCTGGATC
ATACGCTTATTTTTGGTCCTCCCGGTTTAGGAAAAACCACACTGGCCAACATTATTGCCAGAGAAATGGGTGGAAACCTC
AAGTCAACTTCAGGCCCGGTGCTTGAGCGTGCCGGTGACCTTGCCGCCATGCTGACCAATCTTGAAGAAGGTGATGTGCT
GTTTATCGACGAAATTCATCGTTTATCACCGGTCATTGAAGAAATTCTCTATCCAGCAATGGAAGATTATCAACTAGACA
TTATGATTGGTGAAGGTCCTGCTGCGCGTTCGATCAAACTAGATCTTCCTCCATTTACACTCGTTGCAGCCACCACGCGC
GCGGGGCTATTGACTTCTCCGCTAAGAGATCGATTTGGTATTGTGCAACGTTTAGAGTTTTATTCTGTTGAAGATCTTAC
TCATATCGTAACCCGCTCGGCAAACTTGATGAATGTTCCTATGACTTCAACAGGTGCCGCCGAGGTTGCACGTCGCTCAC
GCGGTACACCACGTATTGCAAATCGTTTATTGCGTCGGGTGCGTGATTATGCACAGGTAAAAGGAACAGGTGAAGTCACT
CATGATATGGCGCAACGTGCGCTCGATATGCTCAATGTCGATAAGGATGGCCTAGACACGCTTGACCGACGCTACTTAAG
CATGTTGCTTGAACGATTCGATGGCGGGCCAGCAGGTGTAGAAGCATTGGCTGCCGCGATGGCAGAAGACAGCGGAACCC
TTGAAGATGTGATCGAACCATACCTCATTCAACAAGGCTATGTAATGCGTACCGCTCGTGGCCGAATTGCCACCAATATG
GCATATTTACAGTTTGGCTTGACTCCTCCTGAACCTAAAAACTAA

Upstream 100 bases:

>100_bases
ATTGAAGCGCAAAAAGCAATTGCAGCTGTCAAAGCTGACTATACAGAAGCCGCAGATTTAATTCGCGCAGCTTTAAAATC
GATGATGAAGTGAGTCTATT

Downstream 100 bases:

>100_bases
ATTTAAAGCGTTTGAAGGGCGATGATCAAAATTGAAGTGATAGCTCTTCAATCTTTAACTGAAGATACAGATGTAAAATG
CTAGAAGATCAAATCATTGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MHDRLISGTEKPEDHFDRAIRPTSLADYIGQPVVREQMEIFIGAARGRGEALDHTLIFGPPGLGKTTLANIIAREMGGNL
KSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVAATTR
AGLLTSPLRDRFGIVQRLEFYSVEDLTHIVTRSANLMNVPMTSTGAAEVARRSRGTPRIANRLLRRVRDYAQVKGTGEVT
HDMAQRALDMLNVDKDGLDTLDRRYLSMLLERFDGGPAGVEALAAAMAEDSGTLEDVIEPYLIQQGYVMRTARGRIATNM
AYLQFGLTPPEPKN

Sequences:

>Translated_334_residues
MHDRLISGTEKPEDHFDRAIRPTSLADYIGQPVVREQMEIFIGAARGRGEALDHTLIFGPPGLGKTTLANIIAREMGGNL
KSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVAATTR
AGLLTSPLRDRFGIVQRLEFYSVEDLTHIVTRSANLMNVPMTSTGAAEVARRSRGTPRIANRLLRRVRDYAQVKGTGEVT
HDMAQRALDMLNVDKDGLDTLDRRYLSMLLERFDGGPAGVEALAAAMAEDSGTLEDVIEPYLIQQGYVMRTARGRIATNM
AYLQFGLTPPEPKN
>Mature_334_residues
MHDRLISGTEKPEDHFDRAIRPTSLADYIGQPVVREQMEIFIGAARGRGEALDHTLIFGPPGLGKTTLANIIAREMGGNL
KSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIEEILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVAATTR
AGLLTSPLRDRFGIVQRLEFYSVEDLTHIVTRSANLMNVPMTSTGAAEVARRSRGTPRIANRLLRRVRDYAQVKGTGEVT
HDMAQRALDMLNVDKDGLDTLDRRYLSMLLERFDGGPAGVEALAAAMAEDSGTLEDVIEPYLIQQGYVMRTARGRIATNM
AYLQFGLTPPEPKN

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=330, Percent_Identity=71.8181818181818, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_ACIAD (Q6F991)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047196.1
- ProteinModelPortal:   Q6F991
- SMR:   Q6F991
- STRING:   Q6F991
- GeneID:   2880556
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2615
- NMPDR:   fig|62977.3.peg.2389
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q6F991
- ProtClustDB:   PRK00080
- BioCyc:   ASP62977:ACIAD2615-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 36744; Mature: 36744

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDRLISGTEKPEDHFDRAIRPTSLADYIGQPVVREQMEIFIGAARGRGEALDHTLIFGP
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCEEEECC
PGLGKTTLANIIAREMGGNLKSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIE
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
EILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVAATTRAGLLTSPLRDRFGIVQRLEF
HHHHHCCCCCEEEEEECCCCCCCEEEECCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHH
YSVEDLTHIVTRSANLMNVPMTSTGAAEVARRSRGTPRIANRLLRRVRDYAQVKGTGEVT
HHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHH
HDMAQRALDMLNVDKDGLDTLDRRYLSMLLERFDGGPAGVEALAAAMAEDSGTLEDVIEP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHH
YLIQQGYVMRTARGRIATNMAYLQFGLTPPEPKN
HHHCCCCEEECCCCHHHHHHHHEEECCCCCCCCC
>Mature Secondary Structure
MHDRLISGTEKPEDHFDRAIRPTSLADYIGQPVVREQMEIFIGAARGRGEALDHTLIFGP
CCCCCCCCCCCCHHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCEEEECC
PGLGKTTLANIIAREMGGNLKSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIE
CCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHH
EILYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVAATTRAGLLTSPLRDRFGIVQRLEF
HHHHHCCCCCEEEEEECCCCCCCEEEECCCCCEEHHHHHHCCHHHHHHHHHHHHHHHHHH
YSVEDLTHIVTRSANLMNVPMTSTGAAEVARRSRGTPRIANRLLRRVRDYAQVKGTGEVT
HHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHH
HDMAQRALDMLNVDKDGLDTLDRRYLSMLLERFDGGPAGVEALAAAMAEDSGTLEDVIEP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHH
YLIQQGYVMRTARGRIATNMAYLQFGLTPPEPKN
HHHCCCCEEECCCCHHHHHHHHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA