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The map label for this gene is queC

Identifier: 50085674

GI number: 50085674

Start: 2557671

End: 2558360

Strand: Direct

Name: queC

Synonym: ACIAD2601

Alternate gene names: 50085674

Gene position: 2557671-2558360 (Clockwise)

Preceding gene: 50085673

Following gene: 50085675

Centisome position: 71.07

GC content: 43.48

Gene sequence:

>690_bases
ATGAATGGAGAATTTGGTATGCGTCCTCGTGCCATTGTTTTATTGTCAGGCGGCCTAGACTCAACTACCTGTTTAGCTTG
GGCACAAGCACGCTATGAATGCATGGCTTTAAGCTTTATGTATGGTCAGCGCTCTACCACCGAGCTTGATGCGGCTAAAG
CCATTGCTCAAAATGCAGGTGTTGAACATCGAGTCATTAATATTGATTTGGCGAATCTTGGTGGCTCTGCACTCACAGAT
CATAATATTGACGTACCTGAGCAGCTACAAGAAGGTATTCCAGTCACTTATGTACCTGCTCGAAACACGATATTTCTGTC
ATATGCACTTGCAGCAGCCGAAGTATTTGGTGCTGAAGCAATAGTGATTGGCGTCAATGCTGTAGATTATTCGGGTTATC
CAGACTGTCGTCCAGAATATATTCAAGCATTTACAAATATGGCACGCTTAGCTACAAAAGCAGGTGTTGAGGGAAAACCT
CTTACATTTGAAACACCTTTGTTACATTTATCCAAAGCGAATATTATACGTTTAGGCATCGAACATGGCGTAGACTATAG
TCAAACCGTTTCCTGCTACCAGGCAGATGCGCAAGGTCGTGCTTGTGGTAAATGTGACAGTTGCCGCTTACGTAAACAAG
GTTTTATTGAAGCTGGTGTCACAGATCCAACACGCTACATACCGCAATAA

Upstream 100 bases:

>100_bases
TTTAGCGCAATGGATTTTAGACGACCACCTCCCAGTTCGTTTTCAGTTACAACTCCATAAACTTTTATGGAATGATGAAA
CAGGTCGTTAAATTATTTTT

Downstream 100 bases:

>100_bases
CAAGGTACAATTTATGAAATTTTTAAATAGCAAACTTCTTCTTTCTTCTGTATTTGCTTCGGCTGCTTTGTTTGCATCGG
TAACCCATGCAGACGACAAC

Product: hypothetical protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNGEFGMRPRAIVLLSGGLDSTTCLAWAQARYECMALSFMYGQRSTTELDAAKAIAQNAGVEHRVINIDLANLGGSALTD
HNIDVPEQLQEGIPVTYVPARNTIFLSYALAAAEVFGAEAIVIGVNAVDYSGYPDCRPEYIQAFTNMARLATKAGVEGKP
LTFETPLLHLSKANIIRLGIEHGVDYSQTVSCYQADAQGRACGKCDSCRLRKQGFIEAGVTDPTRYIPQ

Sequences:

>Translated_229_residues
MNGEFGMRPRAIVLLSGGLDSTTCLAWAQARYECMALSFMYGQRSTTELDAAKAIAQNAGVEHRVINIDLANLGGSALTD
HNIDVPEQLQEGIPVTYVPARNTIFLSYALAAAEVFGAEAIVIGVNAVDYSGYPDCRPEYIQAFTNMARLATKAGVEGKP
LTFETPLLHLSKANIIRLGIEHGVDYSQTVSCYQADAQGRACGKCDSCRLRKQGFIEAGVTDPTRYIPQ
>Mature_229_residues
MNGEFGMRPRAIVLLSGGLDSTTCLAWAQARYECMALSFMYGQRSTTELDAAKAIAQNAGVEHRVINIDLANLGGSALTD
HNIDVPEQLQEGIPVTYVPARNTIFLSYALAAAEVFGAEAIVIGVNAVDYSGYPDCRPEYIQAFTNMARLATKAGVEGKP
LTFETPLLHLSKANIIRLGIEHGVDYSQTVSCYQADAQGRACGKCDSCRLRKQGFIEAGVTDPTRYIPQ

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=223, Percent_Identity=39.4618834080717, Blast_Score=144, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_ACIAD (Q6F9A3)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047184.1
- ProteinModelPortal:   Q6F9A3
- SMR:   Q6F9A3
- STRING:   Q6F9A3
- GeneID:   2878193
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2601
- NMPDR:   fig|62977.3.peg.2377
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- PhylomeDB:   Q6F9A3
- ProtClustDB:   CLSK707614
- BioCyc:   ASP62977:ACIAD2601-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 24755; Mature: 24755

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGEFGMRPRAIVLLSGGLDSTTCLAWAQARYECMALSFMYGQRSTTELDAAKAIAQNAG
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHEEEEHHCCCCCCHHHHHHHHHHHCC
VEHRVINIDLANLGGSALTDHNIDVPEQLQEGIPVTYVPARNTIFLSYALAAAEVFGAEA
CCEEEEEEEECCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCEEEEHHHHHHHHHHCCEE
IVIGVNAVDYSGYPDCRPEYIQAFTNMARLATKAGVEGKPLTFETPLLHLSKANIIRLGI
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEECCCCEEEEEH
EHGVDYSQTVSCYQADAQGRACGKCDSCRLRKQGFIEAGVTDPTRYIPQ
HHCCCHHHHHHHEECCCCCCCCCCCCCCHHHHCCCEECCCCCCHHCCCC
>Mature Secondary Structure
MNGEFGMRPRAIVLLSGGLDSTTCLAWAQARYECMALSFMYGQRSTTELDAAKAIAQNAG
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHEEEEHHCCCCCCHHHHHHHHHHHCC
VEHRVINIDLANLGGSALTDHNIDVPEQLQEGIPVTYVPARNTIFLSYALAAAEVFGAEA
CCEEEEEEEECCCCCCCCCCCCCCCHHHHHCCCCEEEECCCCEEEEHHHHHHHHHHCCEE
IVIGVNAVDYSGYPDCRPEYIQAFTNMARLATKAGVEGKPLTFETPLLHLSKANIIRLGI
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEECCCCEEEEEH
EHGVDYSQTVSCYQADAQGRACGKCDSCRLRKQGFIEAGVTDPTRYIPQ
HHCCCHHHHHHHEECCCCCCCCCCCCCCHHHHCCCEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA