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The map label for this gene is dapD

Identifier: 50085672

GI number: 50085672

Start: 2556037

End: 2556858

Strand: Direct

Name: dapD

Synonym: ACIAD2599

Alternate gene names: 50085672

Gene position: 2556037-2556858 (Clockwise)

Preceding gene: 50085670

Following gene: 50085673

Centisome position: 71.03

GC content: 42.58

Gene sequence:

>822_bases
ATGTCTCAGCTCTCAACCATCATTGAGCAAGCGTTTGAAAATCGCGCAAACTTTACAGCTGCTGATTGCCCTGCAGATAT
CCGTCAAGCTGTTGAAGAAGCGTTGTCTGGTTTAGATAATGGTACTTTACGTGTCGCTGAAAAAATTGATGGTGAATGGA
TTGTTCACCAATGGTTAAAAAAAGCTGTTCTTTTATCGTTTAAACTCAATGACAATAAACCAATTGAGTCAGGCGACTTA
GCTTTTTATGACAAAGTAGATACCAAATTTGCAGGCTGGACTGAAGAACAATTCAAAGAAGCAGGTGTTCGAGTTGTTCC
ACCTGCGGTTGCACGTCGTGGTAGCTATCAGGCAAAAAATGTGGTGTTAATGCCTTCATATGTCAATATTGGTGCATATG
TTGACGAAAACACAATGGTTGATACTTGGGCAACTGTTGGCTCATGTGCGCAAATTGGTAAGAATGTACACTTGTCTGGT
GGTGTGGGTATTGGCGGTGTACTTGAGCCACTTCAAGCCAACCCAACTATCATCGAAGATAACTGTTTCATCGGTGCACG
TTCTGAAATCGTTGAAGGCGTGATTGTTGAAGAAGGTGCCGTGATTTCAATGGGCGTTTATATTGGTCAATCGACTCGTA
TTTATGACCGTGAAACTGGTGAAATCCATTATGGTCGCGTTCCTGCGGGTTCAGTGGTTGTACCAGGCAGCTTACCATCT
AAAGATGGTAAATATAGCTTGTACGCTGCTATTATTGTGAAGAAAGTGGATGCGCAAACACGTGCTAAAACCAGCTTGAA
CGATTTGCTTCGCGCTGATTAA

Upstream 100 bases:

>100_bases
AAGACGCGTCGCATATTTTTTAACCACGATATCCGCTTATTCCAAGATTCTTACATTGATTTAGTGTAAAATCGTTAAAA
TTTTTTTTGGAAGGACAACT

Downstream 100 bases:

>100_bases
TTCCATTTATTTGCGAAGCTTTAGTCGCTTCTCGTCTCTACGCTCAGTCATGGTCGTAGAGATTTTTGTTTTCTAATCTT
GGTAATTCTGCAATGACTTC

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSQLSTIIEQAFENRANFTAADCPADIRQAVEEALSGLDNGTLRVAEKIDGEWIVHQWLKKAVLLSFKLNDNKPIESGDL
AFYDKVDTKFAGWTEEQFKEAGVRVVPPAVARRGSYQAKNVVLMPSYVNIGAYVDENTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGAVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVPGSLPS
KDGKYSLYAAIIVKKVDAQTRAKTSLNDLLRAD

Sequences:

>Translated_273_residues
MSQLSTIIEQAFENRANFTAADCPADIRQAVEEALSGLDNGTLRVAEKIDGEWIVHQWLKKAVLLSFKLNDNKPIESGDL
AFYDKVDTKFAGWTEEQFKEAGVRVVPPAVARRGSYQAKNVVLMPSYVNIGAYVDENTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGAVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVPGSLPS
KDGKYSLYAAIIVKKVDAQTRAKTSLNDLLRAD
>Mature_272_residues
SQLSTIIEQAFENRANFTAADCPADIRQAVEEALSGLDNGTLRVAEKIDGEWIVHQWLKKAVLLSFKLNDNKPIESGDLA
FYDKVDTKFAGWTEEQFKEAGVRVVPPAVARRGSYQAKNVVLMPSYVNIGAYVDENTMVDTWATVGSCAQIGKNVHLSGG
VGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGAVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVPGSLPSK
DGKYSLYAAIIVKKVDAQTRAKTSLNDLLRAD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=271, Percent_Identity=74.5387453874539, Blast_Score=399, Evalue=1e-113,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_ACIAD (Q6F9A5)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047182.1
- ProteinModelPortal:   Q6F9A5
- SMR:   Q6F9A5
- STRING:   Q6F9A5
- GeneID:   2878255
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2599
- NMPDR:   fig|62977.3.peg.2375
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- PhylomeDB:   Q6F9A5
- ProtClustDB:   PRK11830
- BioCyc:   ASP62977:ACIAD2599-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29536; Mature: 29405

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 104-104 BINDING 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLSTIIEQAFENRANFTAADCPADIRQAVEEALSGLDNGTLRVAEKIDGEWIVHQWLK
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHCCCCHHHHHHHH
KAVLLSFKLNDNKPIESGDLAFYDKVDTKFAGWTEEQFKEAGVRVVPPAVARRGSYQAKN
HHEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCEEECHHHHCCCCCCCCC
VVLMPSYVNIGAYVDENTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIED
EEEECCEEEECEEECCCCEEHHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCCEEEC
NCFIGARSEIVEGVIVEEGAVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVPGSLPS
CCEECCHHHHHCCEEECCCCEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEECCCCCC
KDGKYSLYAAIIVKKVDAQTRAKTSLNDLLRAD
CCCCEEEEEEEEHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQLSTIIEQAFENRANFTAADCPADIRQAVEEALSGLDNGTLRVAEKIDGEWIVHQWLK
CHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHCCCCHHHHHHHH
KAVLLSFKLNDNKPIESGDLAFYDKVDTKFAGWTEEQFKEAGVRVVPPAVARRGSYQAKN
HHEEEEEEECCCCCCCCCCEEEEECCCCCCCCCCHHHHHHCCCEEECHHHHCCCCCCCCC
VVLMPSYVNIGAYVDENTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIED
EEEECCEEEECEEECCCCEEHHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCCEEEC
NCFIGARSEIVEGVIVEEGAVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVPGSLPS
CCEECCHHHHHCCEEECCCCEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEECCCCCC
KDGKYSLYAAIIVKKVDAQTRAKTSLNDLLRAD
CCCCEEEEEEEEHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA