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The map label for this gene is soxB [H]

Identifier: 50085629

GI number: 50085629

Start: 2511852

End: 2513090

Strand: Reverse

Name: soxB [H]

Synonym: ACIAD2552

Alternate gene names: 50085629

Gene position: 2513090-2511852 (Counterclockwise)

Preceding gene: 50085630

Following gene: 50085628

Centisome position: 69.83

GC content: 46.89

Gene sequence:

>1239_bases
ATGCCTTTGAGTCTGCTGAAGTATGGATTAAGTGATGAGTATCCTGTGGAAGTGGATTTGCCACCACCCAAGGAACTTAA
GTCTCATTATGACGTTGTGATTATTGGTGGAGGTGGACATGGTTTGGCGATTGCCTACTATTTATCGAAATATCATGGCA
TCAGTAATGTAGCGGTACTGGAAAAATCATATTTGGGCGGCGGCAATACGGCACGTAATACCGCAGTGATTCGTTCCAAT
TATCTGACTTCCGACGGTGTGAAGTTTTATGCCGAGTCGGTTCGAATGTTTAAAAATCTATCAAATGAATTTGATTTTAA
CATTATGTACTCCGAGCGTGGTCAATTGACCTTGGCGCATACAGATTCGACAGTTCGAGCATTTCGCCAGCGTGCAGAAG
TCAACAAGCATTTCGGTGGCCGCACCGAAATGATTGATCGAAAGCAAATTAAGGAACTGGTGCCATGTCTCAATCTGGAT
CCTGCGCATTTACCTGTATTGGCTGGGTTGTGGCATATCGATGGTGCGACTGCACGTCATGACGCCGTCGCGTGGGGATA
TGCCAAAGAAGCGGCAAAGCGTGGTGTGGAAATTCATCAGCTCACCGAAGTTCAAGATTTTGTGGTGCAAGGCAATAAGG
TCACAGCAGTCAAAACCAATCGAGGTATGGTGCAATGTGGTTGTGTGGTTCAGGCGATTGCGGGCGCATCTTCCATTTTA
ATGAATAAGCTCAAGATCCGCGCGCCGATTCATACCTATCCTTTACAGGCCATGGTGTCACAACCGTTTAAGCCATTTAT
CAATCCGCTGGTAAGTTCTTCTGCGCTACATTGTTATGTGCAGCAAACCAGTCGGGGAGAAATTGTGTTTGGTGGGGGAT
CAGACCCGTATCCGTTGTACAACACACGCTCAACCTTAGATTTAAAAGAAAGCCTGCTTGCCCATGCGATTGAAATGTTT
CCGTTTATGGCCAATGTCAAGCTGATGCGTCAATGGGCGGGAATGACCGATATGACGCCAGATTATAGTCCGATTATGGG
GAAATCGCCGTATGACAACTATTATCTGGATGCAGGTTGGGGCACTTGGGGCTTTAAATCGACACCAATTTGCGGCAAAA
CCATGGCAGAGCTGGTCGCAACGGGGCGTACGCCAGATTTGATCAAGCCATTTGAGCTGTCGCGCTTTAGTCGTTTTCAA
CAAGTTAATGAAATGGGCGCAACTGCGGCGAGCCATTAA

Upstream 100 bases:

>100_bases
TTGCGTATTTGATGAAAAATACCTTGCAGGCGGTACGTTTGCAGCATCCACAAATATAAATGATGAAAAGGCGTTATGAC
ACGCCGCGGAGAAATACACC

Downstream 100 bases:

>100_bases
GGAGAATATGAAATGAAAATTATGCATTGTCCTTTAAATGGGCCACGAAATATCAGCGAATTTACCTATGGTGGTGAGTT
TAAAGACATGCCGGATCAGA

Product: sarcosine oxidase beta subunit

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MPLSLLKYGLSDEYPVEVDLPPPKELKSHYDVVIIGGGGHGLAIAYYLSKYHGISNVAVLEKSYLGGGNTARNTAVIRSN
YLTSDGVKFYAESVRMFKNLSNEFDFNIMYSERGQLTLAHTDSTVRAFRQRAEVNKHFGGRTEMIDRKQIKELVPCLNLD
PAHLPVLAGLWHIDGATARHDAVAWGYAKEAAKRGVEIHQLTEVQDFVVQGNKVTAVKTNRGMVQCGCVVQAIAGASSIL
MNKLKIRAPIHTYPLQAMVSQPFKPFINPLVSSSALHCYVQQTSRGEIVFGGGSDPYPLYNTRSTLDLKESLLAHAIEMF
PFMANVKLMRQWAGMTDMTPDYSPIMGKSPYDNYYLDAGWGTWGFKSTPICGKTMAELVATGRTPDLIKPFELSRFSRFQ
QVNEMGATAASH

Sequences:

>Translated_412_residues
MPLSLLKYGLSDEYPVEVDLPPPKELKSHYDVVIIGGGGHGLAIAYYLSKYHGISNVAVLEKSYLGGGNTARNTAVIRSN
YLTSDGVKFYAESVRMFKNLSNEFDFNIMYSERGQLTLAHTDSTVRAFRQRAEVNKHFGGRTEMIDRKQIKELVPCLNLD
PAHLPVLAGLWHIDGATARHDAVAWGYAKEAAKRGVEIHQLTEVQDFVVQGNKVTAVKTNRGMVQCGCVVQAIAGASSIL
MNKLKIRAPIHTYPLQAMVSQPFKPFINPLVSSSALHCYVQQTSRGEIVFGGGSDPYPLYNTRSTLDLKESLLAHAIEMF
PFMANVKLMRQWAGMTDMTPDYSPIMGKSPYDNYYLDAGWGTWGFKSTPICGKTMAELVATGRTPDLIKPFELSRFSRFQ
QVNEMGATAASH
>Mature_411_residues
PLSLLKYGLSDEYPVEVDLPPPKELKSHYDVVIIGGGGHGLAIAYYLSKYHGISNVAVLEKSYLGGGNTARNTAVIRSNY
LTSDGVKFYAESVRMFKNLSNEFDFNIMYSERGQLTLAHTDSTVRAFRQRAEVNKHFGGRTEMIDRKQIKELVPCLNLDP
AHLPVLAGLWHIDGATARHDAVAWGYAKEAAKRGVEIHQLTEVQDFVVQGNKVTAVKTNRGMVQCGCVVQAIAGASSILM
NKLKIRAPIHTYPLQAMVSQPFKPFINPLVSSSALHCYVQQTSRGEIVFGGGSDPYPLYNTRSTLDLKESLLAHAIEMFP
FMANVKLMRQWAGMTDMTPDYSPIMGKSPYDNYYLDAGWGTWGFKSTPICGKTMAELVATGRTPDLIKPFELSRFSRFQQ
VNEMGATAASH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI194306651, Length=394, Percent_Identity=25.8883248730964, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI197927446, Length=396, Percent_Identity=21.969696969697, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI21361378, Length=396, Percent_Identity=21.969696969697, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI24797151, Length=415, Percent_Identity=22.6506024096386, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1787438, Length=330, Percent_Identity=25.4545454545455, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI20130091, Length=399, Percent_Identity=24.3107769423559, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28571104, Length=389, Percent_Identity=22.3650385604113, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45612; Mature: 45481

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSLLKYGLSDEYPVEVDLPPPKELKSHYDVVIIGGGGHGLAIAYYLSKYHGISNVAVL
CCHHHHHHCCCCCCCEEECCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHEEH
EKSYLGGGNTARNTAVIRSNYLTSDGVKFYAESVRMFKNLSNEFDFNIMYSERGQLTLAH
HHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEE
TDSTVRAFRQRAEVNKHFGGRTEMIDRKQIKELVPCLNLDPAHLPVLAGLWHIDGATARH
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCC
DAVAWGYAKEAAKRGVEIHQLTEVQDFVVQGNKVTAVKTNRGMVQCGCVVQAIAGASSIL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHCHHHHH
MNKLKIRAPIHTYPLQAMVSQPFKPFINPLVSSSALHCYVQQTSRGEIVFGGGSDPYPLY
HHHHHCCCCCHHCCHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCC
NTRSTLDLKESLLAHAIEMFPFMANVKLMRQWAGMTDMTPDYSPIMGKSPYDNYYLDAGW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCC
GTWGFKSTPICGKTMAELVATGRTPDLIKPFELSRFSRFQQVNEMGATAASH
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PLSLLKYGLSDEYPVEVDLPPPKELKSHYDVVIIGGGGHGLAIAYYLSKYHGISNVAVL
CHHHHHHCCCCCCCEEECCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCHHEEH
EKSYLGGGNTARNTAVIRSNYLTSDGVKFYAESVRMFKNLSNEFDFNIMYSERGQLTLAH
HHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEE
TDSTVRAFRQRAEVNKHFGGRTEMIDRKQIKELVPCLNLDPAHLPVLAGLWHIDGATARH
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCC
DAVAWGYAKEAAKRGVEIHQLTEVQDFVVQGNKVTAVKTNRGMVQCGCVVQAIAGASSIL
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHHHHHHCHHHHH
MNKLKIRAPIHTYPLQAMVSQPFKPFINPLVSSSALHCYVQQTSRGEIVFGGGSDPYPLY
HHHHHCCCCCHHCCHHHHHCCCHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCC
NTRSTLDLKESLLAHAIEMFPFMANVKLMRQWAGMTDMTPDYSPIMGKSPYDNYYLDAGW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEECCC
GTWGFKSTPICGKTMAELVATGRTPDLIKPFELSRFSRFQQVNEMGATAASH
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]