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The map label for this gene is mauR [H]

Identifier: 50085610

GI number: 50085610

Start: 2489550

End: 2490416

Strand: Direct

Name: mauR [H]

Synonym: ACIAD2533

Alternate gene names: 50085610

Gene position: 2489550-2490416 (Clockwise)

Preceding gene: 50085608

Following gene: 50085611

Centisome position: 69.18

GC content: 42.45

Gene sequence:

>867_bases
ATGCATTGGGATGATGTGAAAGTTTTTCTTGCAGTTGCCCGAACAGGCACACTCACCACCGCTGCCGAAAAATTAAATTT
AGGTATTGCCACCGTATCGAGGCGTTTGGAGCGCCTAGAGCAAGATATGGCCATGACGCTGTTTACGCGACATCAAACAG
GTTATCAACTTACACTCGAAGGTGAAGCCTTACTTAGTAATGCAGAAGCATTCGAAAATGCAGCACTCAGCCTGACAGAA
AGTGGACAGAATCATGCACAAGCACAGGGATTGGTTCGTTTAGCCGTTTCAGAAAATCTGGCCAATGGTTTGATAATTCC
TTCCTTACAGTCGCTTTTCTCTCGCCATCCCGAGTTACGTATTGAAATTAACAGTGGCGTTCAACTCACTAACTTGCATC
GTCGAGATGCCGATTTAGCCATTAGAACGATTCAACCTGACGTTGGTAATCTCACCATTAAACGCTTAGGAACACTTCGT
TTTGGACTCTATGCCGCCACGTCTTACATGAAGTTTATTCAAGACCATGATCTTCATCCTGATCAATGTCATTATGTAGG
TTGGGCAGATACCCATCAACATTTGTCACTTGCACACTGGATGAAAGACTTTACACGAAACCAAAATTTTAAGATTGAAA
CCAATAGTCTTTCCACACAAATCGATGCTGTGAAATCTGGCTTAGGTATTGGTCTGTTGCCAGACTTTATTGCAAATCAA
TTAGGACTTGTTCAAATCAATGATAACACTCTAGTTGAACAACCCATCTGGTTGGTGGCACACAGTAACTTGATTACAGC
CAAAAGAATCAGAACTGTGATGGATCATCTGATCCAGCTCTTTGCAGAGCATCCTTCATTTCAGTAA

Upstream 100 bases:

>100_bases
ATTTATGTATCCTCAATATGCGAAAGCCGAAGTATCTATTTCCATGATTGAAATTTATATAGATAATAATTGAAATCAGT
TTTTCATTTTTGGAAAATAT

Downstream 100 bases:

>100_bases
TCAAATCAAAATCCTCATTGCATCTACTAACGGCTATTTAGGCAACTTGATCAGGTCTGACACTGAGAAAATTTAGTGCA
AAAAACCATCATGGTATAAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MHWDDVKVFLAVARTGTLTTAAEKLNLGIATVSRRLERLEQDMAMTLFTRHQTGYQLTLEGEALLSNAEAFENAALSLTE
SGQNHAQAQGLVRLAVSENLANGLIIPSLQSLFSRHPELRIEINSGVQLTNLHRRDADLAIRTIQPDVGNLTIKRLGTLR
FGLYAATSYMKFIQDHDLHPDQCHYVGWADTHQHLSLAHWMKDFTRNQNFKIETNSLSTQIDAVKSGLGIGLLPDFIANQ
LGLVQINDNTLVEQPIWLVAHSNLITAKRIRTVMDHLIQLFAEHPSFQ

Sequences:

>Translated_288_residues
MHWDDVKVFLAVARTGTLTTAAEKLNLGIATVSRRLERLEQDMAMTLFTRHQTGYQLTLEGEALLSNAEAFENAALSLTE
SGQNHAQAQGLVRLAVSENLANGLIIPSLQSLFSRHPELRIEINSGVQLTNLHRRDADLAIRTIQPDVGNLTIKRLGTLR
FGLYAATSYMKFIQDHDLHPDQCHYVGWADTHQHLSLAHWMKDFTRNQNFKIETNSLSTQIDAVKSGLGIGLLPDFIANQ
LGLVQINDNTLVEQPIWLVAHSNLITAKRIRTVMDHLIQLFAEHPSFQ
>Mature_288_residues
MHWDDVKVFLAVARTGTLTTAAEKLNLGIATVSRRLERLEQDMAMTLFTRHQTGYQLTLEGEALLSNAEAFENAALSLTE
SGQNHAQAQGLVRLAVSENLANGLIIPSLQSLFSRHPELRIEINSGVQLTNLHRRDADLAIRTIQPDVGNLTIKRLGTLR
FGLYAATSYMKFIQDHDLHPDQCHYVGWADTHQHLSLAHWMKDFTRNQNFKIETNSLSTQIDAVKSGLGIGLLPDFIANQ
LGLVQINDNTLVEQPIWLVAHSNLITAKRIRTVMDHLIQLFAEHPSFQ

Specific function: Transcriptional activator of the mau genes involved in methylamine metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=25.9259259259259, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081978, Length=303, Percent_Identity=26.0726072607261, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32286; Mature: 32286

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHWDDVKVFLAVARTGTLTTAAEKLNLGIATVSRRLERLEQDMAMTLFTRHQTGYQLTLE
CCCCHHEEEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEC
GEALLSNAEAFENAALSLTESGQNHAQAQGLVRLAVSENLANGLIIPSLQSLFSRHPELR
CHHHHHHHHHHHHHHEEEECCCCCHHHHHHHEEEEEHHHCCCCEECHHHHHHHCCCCCEE
IEINSGVQLTNLHRRDADLAIRTIQPDVGNLTIKRLGTLRFGLYAATSYMKFIQDHDLHP
EEECCCEEEEECCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DQCHYVGWADTHQHLSLAHWMKDFTRNQNFKIETNSLSTQIDAVKSGLGIGLLPDFIANQ
CCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCCCHHHHHCC
LGLVQINDNTLVEQPIWLVAHSNLITAKRIRTVMDHLIQLFAEHPSFQ
CCEEEECCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHWDDVKVFLAVARTGTLTTAAEKLNLGIATVSRRLERLEQDMAMTLFTRHQTGYQLTLE
CCCCHHEEEEEECCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEC
GEALLSNAEAFENAALSLTESGQNHAQAQGLVRLAVSENLANGLIIPSLQSLFSRHPELR
CHHHHHHHHHHHHHHEEEECCCCCHHHHHHHEEEEEHHHCCCCEECHHHHHHHCCCCCEE
IEINSGVQLTNLHRRDADLAIRTIQPDVGNLTIKRLGTLRFGLYAATSYMKFIQDHDLHP
EEECCCEEEEECCCCCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DQCHYVGWADTHQHLSLAHWMKDFTRNQNFKIETNSLSTQIDAVKSGLGIGLLPDFIANQ
CCEEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCCCCHHHHHCC
LGLVQINDNTLVEQPIWLVAHSNLITAKRIRTVMDHLIQLFAEHPSFQ
CCEEEECCCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7957249 [H]