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The map label for this gene is kipA [H]

Identifier: 50085597

GI number: 50085597

Start: 2474207

End: 2475805

Strand: Reverse

Name: kipA [H]

Synonym: ACIAD2518

Alternate gene names: 50085597

Gene position: 2475805-2474207 (Counterclockwise)

Preceding gene: 50085598

Following gene: 50085596

Centisome position: 68.8

GC content: 44.59

Gene sequence:

>1599_bases
TTGCAAAATATGCGTTTTTTAGCCGTCAATCTGGACAGTTTTTTAATTGAACTGAATGATCCTGAACATACTGTTGCGTT
GTTTCGTCATTTAGAAACTATCAAACATCCTCATATTGTAGAAATGATTCCTGCTGCCACCACTATTTTGGTTTATTTTG
ATCGATTAAATACCGAAGTCAGTGCACTTATCCGTTACATCAAATCACAAAGGATTGAGAGGCAGCAACGGCATTCTGTA
GCCAAAGTGGTGATTGATGTGACCTATGATGGTCCAGATTTGCATCATGTTGCTGAATTATTGGGTGTAACGGTGTCTGA
AGTGATTTATCGGCATAGTAATACCTGTTGGAACGTTGCATTTATTGGTTTTGCACCAGGGTTTGGTTATCTAAACAGTC
CAGATCATCCATTTGGGAGCATTCCACGATTAAGCTCACCACGTAAAAAAATTCAGGCAGGTTCTGTTGCATTGGCAGGG
GAATATACAGGTATCTATCCTAAAGATAGCCCTGGTGGATGGCAGTTGATCGGATCTACTCCCCAACAGATGTGGGACAT
ACATCGTGATCCACCTGCACTATTACGGGCTGGCGCTCAGGTGATATTCCGTGATATTACACGCCAGCCCAGCCATGTGG
TCGTACCCGAAATTAAAATACCTAGGCAGCCTGAGCAACATCTTCAGCCTGTTTTTGAATTATTACAAACTGGTTTGCAA
AGTCTGGTTCAAGATCAGGGGCGAACACATCAAGCTGCACTTGGCGTGGGGCGTTCGGGGGCAATGGATCAGACTGCATT
GTCTCAGGCAAATCGTATTGTGGGAAATCCTGATCATGCTGCGGTCATTGAAATCCTGAACGGTGGCTTAAAGCTAAAAG
TGTTGCAATCTACTGTCGTTGCAGTCACGGGAGCAGCAAGTCATATTGGGGTGAGCTATGCAGGTCAGGCCCAGGTCAAG
GTGCCCGATTATTCACCTATTGCACTGGATTGTGGTGATCTGCTTTATATCGATTCCCCGCATGCGGGCTTACGCCATTA
TCTTGCCATTCGCGGCGGCATTAAAACAGAAAAAATACTCGGCAGTGCAAGTTTTGACACGTTGGCAGAACTAGGTACGC
CACCTTTAAAACCGCATGATTTTATTTATTCAGCAGAATTATCGGTTGGCAGTGTCTTACTTCATGAAAAATGCGCACAA
CAGCTTCCAAAAATAGGCGATGTAGTTGAAGTAGATGTAATCCTCGGCCCACGTACGGACTGGTTTGAGCCAGAAAGTCT
AACTCAGTTTTTTCAACAGCAATGGTTGGTGACGCAGGAAAGTAATCGGATTGGTTTACGTTTAAGTGCCGGGTTACCGC
TTAAACGTCAGATTCATGGTGAGCTTGCCAGTGAAGGAACCTGTACAGGTGCCTTACAGATCCCGCCGAATGGACAGCCT
GTTTTATTCATGAATGATCATCCACTTACGGGTGGTTATCCGGTACTAGGTGCTATTGCCATTGACCATCTAGACCGTGT
TGCCCAGATTCCGCCAGGTTGTTTGATACAGTTTCGTCAAAAGTCAGAAATTTTAGATTTGGATAAAGAGTCAACATGA

Upstream 100 bases:

>100_bases
CTCTAAAGTACCTTTTGCGATCAGCCATGCACCTGGATATATGCTGATTACAGACGTGCCAGATCAAGCATGGATGCTAT
AAACCAGAGGTCAAGGGAGA

Downstream 100 bases:

>100_bases
ACAATCAAAAACATAAAATTTTAATTGCCAACCGTGGTGAAATTGCAGTGCGAATTATTCAGGCGTGTAAAGATCTGGAT
ATTGGATCTGTGGCAATTTA

Product: allophanate hydrolase subunit 1 and 2

Products: NA

Alternate protein names: Protein kipA [H]

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MQNMRFLAVNLDSFLIELNDPEHTVALFRHLETIKHPHIVEMIPAATTILVYFDRLNTEVSALIRYIKSQRIERQQRHSV
AKVVIDVTYDGPDLHHVAELLGVTVSEVIYRHSNTCWNVAFIGFAPGFGYLNSPDHPFGSIPRLSSPRKKIQAGSVALAG
EYTGIYPKDSPGGWQLIGSTPQQMWDIHRDPPALLRAGAQVIFRDITRQPSHVVVPEIKIPRQPEQHLQPVFELLQTGLQ
SLVQDQGRTHQAALGVGRSGAMDQTALSQANRIVGNPDHAAVIEILNGGLKLKVLQSTVVAVTGAASHIGVSYAGQAQVK
VPDYSPIALDCGDLLYIDSPHAGLRHYLAIRGGIKTEKILGSASFDTLAELGTPPLKPHDFIYSAELSVGSVLLHEKCAQ
QLPKIGDVVEVDVILGPRTDWFEPESLTQFFQQQWLVTQESNRIGLRLSAGLPLKRQIHGELASEGTCTGALQIPPNGQP
VLFMNDHPLTGGYPVLGAIAIDHLDRVAQIPPGCLIQFRQKSEILDLDKEST

Sequences:

>Translated_532_residues
MQNMRFLAVNLDSFLIELNDPEHTVALFRHLETIKHPHIVEMIPAATTILVYFDRLNTEVSALIRYIKSQRIERQQRHSV
AKVVIDVTYDGPDLHHVAELLGVTVSEVIYRHSNTCWNVAFIGFAPGFGYLNSPDHPFGSIPRLSSPRKKIQAGSVALAG
EYTGIYPKDSPGGWQLIGSTPQQMWDIHRDPPALLRAGAQVIFRDITRQPSHVVVPEIKIPRQPEQHLQPVFELLQTGLQ
SLVQDQGRTHQAALGVGRSGAMDQTALSQANRIVGNPDHAAVIEILNGGLKLKVLQSTVVAVTGAASHIGVSYAGQAQVK
VPDYSPIALDCGDLLYIDSPHAGLRHYLAIRGGIKTEKILGSASFDTLAELGTPPLKPHDFIYSAELSVGSVLLHEKCAQ
QLPKIGDVVEVDVILGPRTDWFEPESLTQFFQQQWLVTQESNRIGLRLSAGLPLKRQIHGELASEGTCTGALQIPPNGQP
VLFMNDHPLTGGYPVLGAIAIDHLDRVAQIPPGCLIQFRQKSEILDLDKEST
>Mature_532_residues
MQNMRFLAVNLDSFLIELNDPEHTVALFRHLETIKHPHIVEMIPAATTILVYFDRLNTEVSALIRYIKSQRIERQQRHSV
AKVVIDVTYDGPDLHHVAELLGVTVSEVIYRHSNTCWNVAFIGFAPGFGYLNSPDHPFGSIPRLSSPRKKIQAGSVALAG
EYTGIYPKDSPGGWQLIGSTPQQMWDIHRDPPALLRAGAQVIFRDITRQPSHVVVPEIKIPRQPEQHLQPVFELLQTGLQ
SLVQDQGRTHQAALGVGRSGAMDQTALSQANRIVGNPDHAAVIEILNGGLKLKVLQSTVVAVTGAASHIGVSYAGQAQVK
VPDYSPIALDCGDLLYIDSPHAGLRHYLAIRGGIKTEKILGSASFDTLAELGTPPLKPHDFIYSAELSVGSVLLHEKCAQ
QLPKIGDVVEVDVILGPRTDWFEPESLTQFFQQQWLVTQESNRIGLRLSAGLPLKRQIHGELASEGTCTGALQIPPNGQP
VLFMNDHPLTGGYPVLGAIAIDHLDRVAQIPPGCLIQFRQKSEILDLDKEST

Specific function: Counteracts the inhibitory action of kipI on sporulation. May bind to kipI, preventing its function as an inhibitor of kinase A [H]

COG id: COG1984

COG function: function code E; Allophanate hydrolase subunit 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786930, Length=293, Percent_Identity=32.0819112627986, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1786929, Length=217, Percent_Identity=35.9447004608295, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6319685, Length=312, Percent_Identity=33.0128205128205, Blast_Score=115, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003778 [H]

Pfam domain/function: PF02626 AHS2 [H]

EC number: NA

Molecular weight: Translated: 58354; Mature: 58354

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNMRFLAVNLDSFLIELNDPEHTVALFRHLETIKHPHIVEMIPAATTILVYFDRLNTEV
CCCCEEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEHHHHCHHH
SALIRYIKSQRIERQQRHSVAKVVIDVTYDGPDLHHVAELLGVTVSEVIYRHSNTCWNVA
HHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
FIGFAPGFGYLNSPDHPFGSIPRLSSPRKKIQAGSVALAGEYTGIYPKDSPGGWQLIGST
EEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCC
PQQMWDIHRDPPALLRAGAQVIFRDITRQPSHVVVPEIKIPRQPEQHLQPVFELLQTGLQ
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
SLVQDQGRTHQAALGVGRSGAMDQTALSQANRIVGNPDHAAVIEILNGGLKLKVLQSTVV
HHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEHHEEE
AVTGAASHIGVSYAGQAQVKVPDYSPIALDCGDLLYIDSPHAGLRHYLAIRGGIKTEKIL
EEECCHHHCCEEECCCEEEECCCCCCEEECCCCEEEECCCCHHHHHHHHHCCCCCHHHHC
GSASFDTLAELGTPPLKPHDFIYSAELSVGSVLLHEKCAQQLPKIGDVVEVDVILGPRTD
CCCCHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCC
WFEPESLTQFFQQQWLVTQESNRIGLRLSAGLPLKRQIHGELASEGTCTGALQIPPNGQP
CCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCE
VLFMNDHPLTGGYPVLGAIAIDHLDRVAQIPPGCLIQFRQKSEILDLDKEST
EEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MQNMRFLAVNLDSFLIELNDPEHTVALFRHLETIKHPHIVEMIPAATTILVYFDRLNTEV
CCCCEEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEHHHHCHHH
SALIRYIKSQRIERQQRHSVAKVVIDVTYDGPDLHHVAELLGVTVSEVIYRHSNTCWNVA
HHHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEEE
FIGFAPGFGYLNSPDHPFGSIPRLSSPRKKIQAGSVALAGEYTGIYPKDSPGGWQLIGST
EEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCC
PQQMWDIHRDPPALLRAGAQVIFRDITRQPSHVVVPEIKIPRQPEQHLQPVFELLQTGLQ
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHH
SLVQDQGRTHQAALGVGRSGAMDQTALSQANRIVGNPDHAAVIEILNGGLKLKVLQSTVV
HHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEHHEEE
AVTGAASHIGVSYAGQAQVKVPDYSPIALDCGDLLYIDSPHAGLRHYLAIRGGIKTEKIL
EEECCHHHCCEEECCCEEEECCCCCCEEECCCCEEEECCCCHHHHHHHHHCCCCCHHHHC
GSASFDTLAELGTPPLKPHDFIYSAELSVGSVLLHEKCAQQLPKIGDVVEVDVILGPRTD
CCCCHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCC
WFEPESLTQFFQQQWLVTQESNRIGLRLSAGLPLKRQIHGELASEGTCTGALQIPPNGQP
CCCHHHHHHHHHHHCCEEECCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCE
VLFMNDHPLTGGYPVLGAIAIDHLDRVAQIPPGCLIQFRQKSEILDLDKEST
EEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]