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The map label for this gene is atoD [H]

Identifier: 50085592

GI number: 50085592

Start: 2468252

End: 2468956

Strand: Direct

Name: atoD [H]

Synonym: ACIAD2513

Alternate gene names: 50085592

Gene position: 2468252-2468956 (Clockwise)

Preceding gene: 50085591

Following gene: 50085593

Centisome position: 68.59

GC content: 41.99

Gene sequence:

>705_bases
ATGGATAAAGTATATAAAAGTGCAGCGCTCGCACTACAGGATATTGTTAAAGATCATCAAACCTTGGCAGTAGGCGGTTT
CGGGCTTTGTGGTATTCCCGAAGCGTTAATTGGTGCATTGAAAGATACACAAGTCAAACATCTGACCTGTATTTCCAACA
ACGCTGGCGTGGATGATTTTGGTTTAGGTTTGTTATTGCAAACCAAACAAATCAAGAAAATGATCTCTTCTTATGTAGGA
GAGAATAAGGAATTTGAACGCCAATATCTCAATGGCGAGCTTGAAGTTGAATTGACACCTCAAGGTACGTTGGCCGAAAA
GCTGCGTGCTGGTGGTGCAGGCATCCCTGCTTTTTACACGCAAACAGGTGTAGGAACTCTTATTGCCGAAGGCAAGGAGC
AACGAGAATTTGATGGGAAAACCTATATTTTAGAACCCTCCTTAACTGCTGATATTGCATTGGTGAAAGCTTATAAAGCA
GACAGAGCAGGCAATCTGGTGTTTCGTAAAACCGCGCGTAATTTTAACCCTGAATGTGCTATGGCTGGAAAAATTACCGT
TGCCGAAGTTGAGCAGATCGTTGAAACAGGCGAACTTGATCCAGATGAAATTCACTTAGCAGGTATTTTTGTACATCGCG
TTGTGCTCAATAGTGCACCAGAAAAACGTATCGAACAAAAAACTTTAAAAGCACAGGGAGCATAA

Upstream 100 bases:

>100_bases
ATTGATTAATTTTACTCATCAAATCTTTAAAATTTTCAACTTCTTTAAATAAATTCAGAATGCTAATAATAAAAACACAC
AGGGATTTTGAGTCATCAAG

Downstream 100 bases:

>100_bases
TCATGGCATGGACACGTGAACAAATGGCACAACGTGCCGCACAGGAATTGCAAGATGGTTTTTATGTCAATCTTGGAATT
GGCTTACCGACGCTAGTCGC

Product: acetoacetyl-CoA transferase, alpha subunit

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MDKVYKSAALALQDIVKDHQTLAVGGFGLCGIPEALIGALKDTQVKHLTCISNNAGVDDFGLGLLLQTKQIKKMISSYVG
ENKEFERQYLNGELEVELTPQGTLAEKLRAGGAGIPAFYTQTGVGTLIAEGKEQREFDGKTYILEPSLTADIALVKAYKA
DRAGNLVFRKTARNFNPECAMAGKITVAEVEQIVETGELDPDEIHLAGIFVHRVVLNSAPEKRIEQKTLKAQGA

Sequences:

>Translated_234_residues
MDKVYKSAALALQDIVKDHQTLAVGGFGLCGIPEALIGALKDTQVKHLTCISNNAGVDDFGLGLLLQTKQIKKMISSYVG
ENKEFERQYLNGELEVELTPQGTLAEKLRAGGAGIPAFYTQTGVGTLIAEGKEQREFDGKTYILEPSLTADIALVKAYKA
DRAGNLVFRKTARNFNPECAMAGKITVAEVEQIVETGELDPDEIHLAGIFVHRVVLNSAPEKRIEQKTLKAQGA
>Mature_234_residues
MDKVYKSAALALQDIVKDHQTLAVGGFGLCGIPEALIGALKDTQVKHLTCISNNAGVDDFGLGLLLQTKQIKKMISSYVG
ENKEFERQYLNGELEVELTPQGTLAEKLRAGGAGIPAFYTQTGVGTLIAEGKEQREFDGKTYILEPSLTADIALVKAYKA
DRAGNLVFRKTARNFNPECAMAGKITVAEVEQIVETGELDPDEIHLAGIFVHRVVLNSAPEKRIEQKTLKAQGA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=249, Percent_Identity=58.2329317269076, Blast_Score=287, Evalue=4e-78,
Organism=Homo sapiens, GI11545841, Length=245, Percent_Identity=52.6530612244898, Blast_Score=241, Evalue=4e-64,
Organism=Escherichia coli, GI1788551, Length=216, Percent_Identity=43.0555555555556, Blast_Score=190, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17531517, Length=251, Percent_Identity=53.7848605577689, Blast_Score=265, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24655794, Length=242, Percent_Identity=55.7851239669422, Blast_Score=261, Evalue=4e-70,
Organism=Drosophila melanogaster, GI21358325, Length=242, Percent_Identity=55.7851239669422, Blast_Score=260, Evalue=4e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25330; Mature: 25330

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVYKSAALALQDIVKDHQTLAVGGFGLCGIPEALIGALKDTQVKHLTCISNNAGVDDF
CCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCC
GLGLLLQTKQIKKMISSYVGENKEFERQYLNGELEVELTPQGTLAEKLRAGGAGIPAFYT
CHHHEEHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
QTGVGTLIAEGKEQREFDGKTYILEPSLTADIALVKAYKADRAGNLVFRKTARNFNPECA
HCCCHHHHHCCCHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCEE
MAGKITVAEVEQIVETGELDPDEIHLAGIFVHRVVLNSAPEKRIEQKTLKAQGA
ECCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MDKVYKSAALALQDIVKDHQTLAVGGFGLCGIPEALIGALKDTQVKHLTCISNNAGVDDF
CCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCC
GLGLLLQTKQIKKMISSYVGENKEFERQYLNGELEVELTPQGTLAEKLRAGGAGIPAFYT
CHHHEEHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
QTGVGTLIAEGKEQREFDGKTYILEPSLTADIALVKAYKADRAGNLVFRKTARNFNPECA
HCCCHHHHHCCCHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCEE
MAGKITVAEVEQIVETGELDPDEIHLAGIFVHRVVLNSAPEKRIEQKTLKAQGA
ECCCEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]