Click here to switch to the map view.

The map label for this gene is atoA [H]

Identifier: 50085593

GI number: 50085593

Start: 2468959

End: 2469603

Strand: Direct

Name: atoA [H]

Synonym: ACIAD2514

Alternate gene names: 50085593

Gene position: 2468959-2469603 (Clockwise)

Preceding gene: 50085592

Following gene: 50085594

Centisome position: 68.61

GC content: 47.75

Gene sequence:

>645_bases
ATGGCATGGACACGTGAACAAATGGCACAACGTGCCGCACAGGAATTGCAAGATGGTTTTTATGTCAATCTTGGAATTGG
CTTACCGACGCTAGTCGCCAATTATATTCCCGCCGATGTAGAAGTCTGGTTGCAATCTGAAAATGGCTTGCTGGGGATTG
GAGAATTTCCGACAGAGGACACTGTAGATGCAGATCTGATTAATGCAGGGAAACAAACCGTCACTGCTCGTGCGGGTGCT
GCATTTTTCTCAAGTAGTGAATCATTTGGCATGATTCGCGGCGGTCATGTCAATATCGCGATTTTAGGCGCAATGGAAGT
TTCTGAAAAAGGAGATTTGGCCAACTGGATGATTCCAGGCAAAAAAGTCAAAGGTATGGGCGGTGCAATGGATCTCGTGG
TCGGTGTGCAACGTGTCGTGGTACTGATGGAACACTGTGCCAAAGATGGCTCAGCCAAAATTGTATCTGAATGCTCACTG
CCACTGACAGGTCAAGGTGTCGTACACCGCATTATTACCGATCTTGGTGTTATGGACATTGTACCCGAAGGTATACAACT
GGTTGAGCTGGCAGATGGCGTTACCTTGCAACAGATTCAAGCTGCCTCGGGCGTTGAGTTATTACAGCACGCTGCCCTTG
CTTAA

Upstream 100 bases:

>100_bases
AAATTCACTTAGCAGGTATTTTTGTACATCGCGTTGTGCTCAATAGTGCACCAGAAAAACGTATCGAACAAAAAACTTTA
AAAGCACAGGGAGCATAATC

Downstream 100 bases:

>100_bases
ATTATAAAGTTAGAACAGATAAGGTTCCATGAAGGAACCTAAAAATAAAGCGTGATCGGCTCAATGAGACTGATCACTCA
AAATACAATAAAAGACGGAT

Product: acetoacetyl-CoA transferase, beta subunit

Products: NA

Alternate protein names: OXCT B; Succinyl CoA:3-oxoacid CoA-transferase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MAWTREQMAQRAAQELQDGFYVNLGIGLPTLVANYIPADVEVWLQSENGLLGIGEFPTEDTVDADLINAGKQTVTARAGA
AFFSSSESFGMIRGGHVNIAILGAMEVSEKGDLANWMIPGKKVKGMGGAMDLVVGVQRVVVLMEHCAKDGSAKIVSECSL
PLTGQGVVHRIITDLGVMDIVPEGIQLVELADGVTLQQIQAASGVELLQHAALA

Sequences:

>Translated_214_residues
MAWTREQMAQRAAQELQDGFYVNLGIGLPTLVANYIPADVEVWLQSENGLLGIGEFPTEDTVDADLINAGKQTVTARAGA
AFFSSSESFGMIRGGHVNIAILGAMEVSEKGDLANWMIPGKKVKGMGGAMDLVVGVQRVVVLMEHCAKDGSAKIVSECSL
PLTGQGVVHRIITDLGVMDIVPEGIQLVELADGVTLQQIQAASGVELLQHAALA
>Mature_213_residues
AWTREQMAQRAAQELQDGFYVNLGIGLPTLVANYIPADVEVWLQSENGLLGIGEFPTEDTVDADLINAGKQTVTARAGAA
FFSSSESFGMIRGGHVNIAILGAMEVSEKGDLANWMIPGKKVKGMGGAMDLVVGVQRVVVLMEHCAKDGSAKIVSECSLP
LTGQGVVHRIITDLGVMDIVPEGIQLVELADGVTLQQIQAASGVELLQHAALA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=205, Percent_Identity=56.5853658536585, Blast_Score=240, Evalue=5e-64,
Organism=Homo sapiens, GI11545841, Length=203, Percent_Identity=57.1428571428571, Blast_Score=240, Evalue=6e-64,
Organism=Escherichia coli, GI1788552, Length=199, Percent_Identity=51.2562814070352, Blast_Score=216, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI17531517, Length=206, Percent_Identity=53.8834951456311, Blast_Score=228, Evalue=2e-60,
Organism=Drosophila melanogaster, GI21358325, Length=205, Percent_Identity=58.5365853658537, Blast_Score=246, Evalue=9e-66,
Organism=Drosophila melanogaster, GI24655794, Length=205, Percent_Identity=58.5365853658537, Blast_Score=245, Evalue=1e-65,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 22569; Mature: 22438

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWTREQMAQRAAQELQDGFYVNLGIGLPTLVANYIPADVEVWLQSENGLLGIGEFPTED
CCCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCC
TVDADLINAGKQTVTARAGAAFFSSSESFGMIRGGHVNIAILGAMEVSEKGDLANWMIPG
CCCHHHHHCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEEEEEEEEECCCCCCCCCCCCC
KKVKGMGGAMDLVVGVQRVVVLMEHCAKDGSAKIVSECSLPLTGQGVVHRIITDLGVMDI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCHHHH
VPEGIQLVELADGVTLQQIQAASGVELLQHAALA
CCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AWTREQMAQRAAQELQDGFYVNLGIGLPTLVANYIPADVEVWLQSENGLLGIGEFPTED
CCCHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCC
TVDADLINAGKQTVTARAGAAFFSSSESFGMIRGGHVNIAILGAMEVSEKGDLANWMIPG
CCCHHHHHCCCHHHHHHHHHHHHCCCCCCCEEECCEEEEEEEEEEEECCCCCCCCCCCCC
KKVKGMGGAMDLVVGVQRVVVLMEHCAKDGSAKIVSECSLPLTGQGVVHRIITDLGVMDI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCHHHH
VPEGIQLVELADGVTLQQIQAASGVELLQHAALA
CCCCCEEEHHCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134 [H]