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The map label for this gene is ubiC

Identifier: 50085539

GI number: 50085539

Start: 2419336

End: 2419839

Strand: Reverse

Name: ubiC

Synonym: ACIAD2456

Alternate gene names: 50085539

Gene position: 2419839-2419336 (Counterclockwise)

Preceding gene: 50085541

Following gene: 50085538

Centisome position: 67.24

GC content: 40.67

Gene sequence:

>504_bases
ATGCAGAAAATTCAATCAAATCAAATACAGGAACAAGATTTGACGCCTGAATTAAAAAAATGGTTGTATGCATCTGGATC
ATTGACTCAGCAATTGACTGATTTGGCGGATGGCTTATTTACAGTTGAACCGATTCAGGAAAAGTATCAGCGTATGAGTT
TTATGGATAGCCGCTGGATGCGTATGCCAGCGTATCATGTGGCCTGGGTGAGAGAAAGTTTGTTATATGGGTGTGAGCAA
CAGCCATGGGTAAAAGCAAAGAGTATTTTCCCTGTTTTAAGTCTGCAAAAAAAGGCCCGTATCTTTAAACACATTGGTAA
AAAACCCATTGGCCGATTTCTGTTTCAGCGCACGACTCCGTTGTGTGAACGGCGTGTGATACGTTTAGAAGAAGGCTGGA
CCAGACAAAGTTGTTATACGTGGCATGGGTGTAAATTTATCGTGCAGGAAACTTTTCTAGCTTCGTTTGAGCAATATATT
CAACATCATTCTCACTCTATATAG

Upstream 100 bases:

>100_bases
TATTAAAGATACATCAACAAAACAATTATTCATGTCAGATTTGAGTTCAGTCATCAATAATTTCGGTTACACTAAATCTT
CTGAATAGATCGGATCCTTT

Downstream 100 bases:

>100_bases
GAATAGTTATGTCGACAGTGCAGCCGATATCATGGCGAGAGCGCCTGCAGGCTTATTATTATTTATGCCGATTTGATAAA
CCTATTGGAACGGAGCTGGT

Product: chorismate pyruvate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MQKIQSNQIQEQDLTPELKKWLYASGSLTQQLTDLADGLFTVEPIQEKYQRMSFMDSRWMRMPAYHVAWVRESLLYGCEQ
QPWVKAKSIFPVLSLQKKARIFKHIGKKPIGRFLFQRTTPLCERRVIRLEEGWTRQSCYTWHGCKFIVQETFLASFEQYI
QHHSHSI

Sequences:

>Translated_167_residues
MQKIQSNQIQEQDLTPELKKWLYASGSLTQQLTDLADGLFTVEPIQEKYQRMSFMDSRWMRMPAYHVAWVRESLLYGCEQ
QPWVKAKSIFPVLSLQKKARIFKHIGKKPIGRFLFQRTTPLCERRVIRLEEGWTRQSCYTWHGCKFIVQETFLASFEQYI
QHHSHSI
>Mature_167_residues
MQKIQSNQIQEQDLTPELKKWLYASGSLTQQLTDLADGLFTVEPIQEKYQRMSFMDSRWMRMPAYHVAWVRESLLYGCEQ
QPWVKAKSIFPVLSLQKKARIFKHIGKKPIGRFLFQRTTPLCERRVIRLEEGWTRQSCYTWHGCKFIVQETFLASFEQYI
QHHSHSI

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_ACIAD (Q6F9N7)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047049.1
- ProteinModelPortal:   Q6F9N7
- SMR:   Q6F9N7
- STRING:   Q6F9N7
- GeneID:   2880802
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2456
- NMPDR:   fig|62977.3.peg.2058
- eggNOG:   COG3161
- HOGENOM:   HBG289129
- OMA:   ISETFLP
- ProtClustDB:   CLSK830668
- BioCyc:   ASP62977:ACIAD2456-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 19927; Mature: 19927

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: BINDING 71-71 BINDING 110-110

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKIQSNQIQEQDLTPELKKWLYASGSLTQQLTDLADGLFTVEPIQEKYQRMSFMDSRWM
CCCCCCCCCCHHCCCHHHHHHHHCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHH
RMPAYHVAWVRESLLYGCEQQPWVKAKSIFPVLSLQKKARIFKHIGKKPIGRFLFQRTTP
HCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCH
LCERRVIRLEEGWTRQSCYTWHGCKFIVQETFLASFEQYIQHHSHSI
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQKIQSNQIQEQDLTPELKKWLYASGSLTQQLTDLADGLFTVEPIQEKYQRMSFMDSRWM
CCCCCCCCCCHHCCCHHHHHHHHCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHH
RMPAYHVAWVRESLLYGCEQQPWVKAKSIFPVLSLQKKARIFKHIGKKPIGRFLFQRTTP
HCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCH
LCERRVIRLEEGWTRQSCYTWHGCKFIVQETFLASFEQYIQHHSHSI
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA