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The map label for this gene is ubiA [H]

Identifier: 50085538

GI number: 50085538

Start: 2418446

End: 2419327

Strand: Reverse

Name: ubiA [H]

Synonym: ACIAD2455

Alternate gene names: 50085538

Gene position: 2419327-2418446 (Counterclockwise)

Preceding gene: 50085539

Following gene: 50085525

Centisome position: 67.23

GC content: 40.14

Gene sequence:

>882_bases
ATGTCGACAGTGCAGCCGATATCATGGCGAGAGCGCCTGCAGGCTTATTATTATTTATGCCGATTTGATAAACCTATTGG
AACGGAGCTGGTGTTTTGGCCGACGATGTGGGCACTCTGGATTGCAAGTGATGGATATCCAGACCTGAAAATGTTTGTCG
TAATGACTTTGGGTGTACTGTTTATGCGGGCAGCAGGCTGTGCGATTAATGATTTTGCAGATCGTAAAGTAGATGGGCAT
GTTGCACGCACCAAACAGCGCCCGCTTGCAACAGGAATTATTCGTCCAATTGAAGCTATCTGGGTGTTTTTAGCATTGGT
TGCTGCAAGTGCGGCTCTGTTGCTATTTTTGCCTATAGAGACATTTTATTGGTCATTTGGTGCATTGTTTTTGGCATTTA
TTTACCCTTTTATGAAACGTTATACCCACTTACCTCAGGTATTTTTGGGTGCGGCTTTTTCATGGGCTATTCCAATGGCA
TATACCGCTACAGGACAAGCACCTGATTTGACATGTTGGCTTTTATATTTTGGTAATCTTGCATGGACCGTGGCTTACGA
TACACAATATGCAATCACAGACCGTGAATATGATTTAAAAATAGGGGTTAAATCAACTGCCATATTATTTAACCGATTTG
ACATTCCAATTATTAGTACATTGCAGTTAAGCAGTCTGTTATTAATAGGAATGGCATTGTATATCGAAAATTTATTGTTT
CCATGGGGAATAATTGGTTTGGTTGTGGTTGCAGTTGACTTTATTTATCAATGGACCAAAACAAAAAACCGAGATCCACA
ATTATGCTTCTGGGCATTTAGGCATAACCGTTGGGTTGGATTGATTATATTTTTAGCAATTCTTGCTGCATTTAGGTTTT
AG

Upstream 100 bases:

>100_bases
GTTATACGTGGCATGGGTGTAAATTTATCGTGCAGGAAACTTTTCTAGCTTCGTTTGAGCAATATATTCAACATCATTCT
CACTCTATATAGGAATAGTT

Downstream 100 bases:

>100_bases
ATAAATTGAACGAACAATGCCTATTACAACGTAATAGGCATCTTTAATATGATTAAATTAAAATGATCGCTGTTAATCCA
CCAATAATTCGAGTCTACTC

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSTVQPISWRERLQAYYYLCRFDKPIGTELVFWPTMWALWIASDGYPDLKMFVVMTLGVLFMRAAGCAINDFADRKVDGH
VARTKQRPLATGIIRPIEAIWVFLALVAASAALLLFLPIETFYWSFGALFLAFIYPFMKRYTHLPQVFLGAAFSWAIPMA
YTATGQAPDLTCWLLYFGNLAWTVAYDTQYAITDREYDLKIGVKSTAILFNRFDIPIISTLQLSSLLLIGMALYIENLLF
PWGIIGLVVVAVDFIYQWTKTKNRDPQLCFWAFRHNRWVGLIIFLAILAAFRF

Sequences:

>Translated_293_residues
MSTVQPISWRERLQAYYYLCRFDKPIGTELVFWPTMWALWIASDGYPDLKMFVVMTLGVLFMRAAGCAINDFADRKVDGH
VARTKQRPLATGIIRPIEAIWVFLALVAASAALLLFLPIETFYWSFGALFLAFIYPFMKRYTHLPQVFLGAAFSWAIPMA
YTATGQAPDLTCWLLYFGNLAWTVAYDTQYAITDREYDLKIGVKSTAILFNRFDIPIISTLQLSSLLLIGMALYIENLLF
PWGIIGLVVVAVDFIYQWTKTKNRDPQLCFWAFRHNRWVGLIIFLAILAAFRF
>Mature_292_residues
STVQPISWRERLQAYYYLCRFDKPIGTELVFWPTMWALWIASDGYPDLKMFVVMTLGVLFMRAAGCAINDFADRKVDGHV
ARTKQRPLATGIIRPIEAIWVFLALVAASAALLLFLPIETFYWSFGALFLAFIYPFMKRYTHLPQVFLGAAFSWAIPMAY
TATGQAPDLTCWLLYFGNLAWTVAYDTQYAITDREYDLKIGVKSTAILFNRFDIPIISTLQLSSLLLIGMALYIENLLFP
WGIIGLVVVAVDFIYQWTKTKNRDPQLCFWAFRHNRWVGLIIFLAILAAFRF

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=279, Percent_Identity=33.6917562724014, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1790473, Length=283, Percent_Identity=49.469964664311, Blast_Score=261, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI32565247, Length=282, Percent_Identity=32.2695035460993, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17553718, Length=282, Percent_Identity=31.9148936170213, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17553720, Length=339, Percent_Identity=27.4336283185841, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI32565245, Length=141, Percent_Identity=39.0070921985816, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32565243, Length=140, Percent_Identity=38.5714285714286, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324370, Length=272, Percent_Identity=33.0882352941176, Blast_Score=143, Evalue=3e-35,
Organism=Drosophila melanogaster, GI21355567, Length=297, Percent_Identity=35.016835016835, Blast_Score=166, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 33687; Mature: 33556

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVQPISWRERLQAYYYLCRFDKPIGTELVFWPTMWALWIASDGYPDLKMFVVMTLGVL
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FMRAAGCAINDFADRKVDGHVARTKQRPLATGIIRPIEAIWVFLALVAASAALLLFLPIE
HHHHCCCCHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFYWSFGALFLAFIYPFMKRYTHLPQVFLGAAFSWAIPMAYTATGQAPDLTCWLLYFGNL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEECCCCCCCCEEHHHHHCCE
AWTVAYDTQYAITDREYDLKIGVKSTAILFNRFDIPIISTLQLSSLLLIGMALYIENLLF
EEEEEECCEEEEECCCEEEEECCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PWGIIGLVVVAVDFIYQWTKTKNRDPQLCFWAFRHNRWVGLIIFLAILAAFRF
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STVQPISWRERLQAYYYLCRFDKPIGTELVFWPTMWALWIASDGYPDLKMFVVMTLGVL
CCCCCCHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FMRAAGCAINDFADRKVDGHVARTKQRPLATGIIRPIEAIWVFLALVAASAALLLFLPIE
HHHHCCCCHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFYWSFGALFLAFIYPFMKRYTHLPQVFLGAAFSWAIPMAYTATGQAPDLTCWLLYFGNL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEECCCCCCCCEEHHHHHCCE
AWTVAYDTQYAITDREYDLKIGVKSTAILFNRFDIPIISTLQLSSLLLIGMALYIENLLF
EEEEEECCEEEEECCCEEEEECCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
PWGIIGLVVVAVDFIYQWTKTKNRDPQLCFWAFRHNRWVGLIIFLAILAAFRF
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA