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The map label for this gene is gidA

Identifier: 50085525

GI number: 50085525

Start: 2405708

End: 2407588

Strand: Reverse

Name: gidA

Synonym: ACIAD2440

Alternate gene names: 50085525

Gene position: 2407588-2405708 (Counterclockwise)

Preceding gene: 50085538

Following gene: 50085523

Centisome position: 66.9

GC content: 44.23

Gene sequence:

>1881_bases
ATGCACTATCCTAAAGTTTATGATGTTATCGTTATCGGTGGCGGTCACGCAGGTACGGAAGCGGCCTTGGCTGCTGCGCG
TATGGGACGGCAGACTTTGCTCTTGACTCATAACATTGAGACTTTAGGGCAAATGAGCTGCAATCCTGCAATTGGTGGGA
TCGGTAAGTCGCATTTGGTGCGTGAAATTGATGCTTTGGGCGGTGCAATGGCACTTGCAGCCGACAAAGGTGGTATTCAG
TTTCGTATTCTAAACTCTCGTAAAGGTGCTGCGGTACGTGCAACACGTGCACAAGCAGACCGTGTGCGTTATAAGGCAGC
GATCCGACATACACTTGAGAATCAAGCCAATTTAGATATTTTTCAGCAAGCTGCCGATGATTTAATTGTAGAAGGCGATA
CCGTAAAAGGTGTGGTTACCCAGATGGGGATTCGCTTTGATACCAAAACAGTCGTTCTCACTACAGGTACTTTCTTGGGC
GGTGTAATTCATATCGGTCTAGAGAAATCGAGTGGTGGTCGTGCAGGTGATCCACCTTCTATCGCGCTGTCACACCGTTT
ACGCGAATTAAATTTACCTGTAGGCCGTTTAAAGACTGGAACACCACCGCGTATTGATGCCCGTTCGGTCGATTTTTCTG
TGATGACGCCTCAACCTGGGGATTTTCCATCTCCTGTGATGTCGTTTATGGGTGATGTTTCGATGCATCCAGAGCAGGTA
AGTTGCTATATCACGCATACCAACGAAAAAACGCATGACATTATTCGTGGCGGATTGGATCGTTCACCTATGTATACTGG
TGTGATTGAAGGGGTAGGACCACGTTATTGCCCATCTATTGAAGACAAGATTCATCGTTTTGCCGACAAAGATTCTCATC
AGGTGTTTTTAGAGCCTGAAGGTTTGGATACACATGAGTTGTATCCAAACGGAATTTCAACATCATTACCTTTTGATGTG
CAGTTTGAATTGGTTCGCTCTATTCGCGGTATGGAAAATGCGCATATTTTACGCCCAGGTTATGCCATCGAATATGATTA
TTTTAACCCTCAAGCTTTAAAATTTACCCTGGAAACCAAAGCAATTAATAACTTGTATTTTGCTGGGCAAATTAATGGCA
CCACAGGTTATGAAGAAGCGGGTGCTCAGGGATTACTTGCAGGTTTAAATGCTGCGCGTCGTGCATGGGATCAAGAGCAA
TGGACACCAAAACGTGATCAGGCTTACATGGGTGTATTGGTAGATGATCTGATTACTTTGGGAACCAAAGAACCATATCG
TATGTTTACATCACGTGCCGAGTATCGTTTGATGCTACGTGAGGACAATGCGGATCAGCGTTTGACACCTGTGGGTCGTG
AAATGGGATTGGTTGATGATGTACGCTGGGCAGCTTACTGTGAAAAGATGGAAGCCGTTGAAACTGAAACTGCACGTTTG
GCCCATTTGTGGGCTGCACCAAATAATCCGATGGGCAAACAATTTGTCGAAATGACAGGTGCAGATTTGAGTAAAGAATG
TAGCGCGATTGATCTGCTCAAACGTCCAAATATTAACTTTACTCAAATTGCAGAGTTGACTGGTTCACAAGTTTCTACAC
AAGTTGGTGACCAGATCGAGATTGCAGTGAAATATGAAGGTTATATCAACCGTCAGCATGAAGATGTCGCTCAATTAAAG
CGTTTGGAAGAAACCAAAATTCCAGCCGATTTTGATTATGATATCGTTTCTGGATTATCTCGTGAAATCACACAAAAGTT
GAAGACTGTTCGTCCCGAAACCTTAGCTCAGGCCCATCGTATTCCAGGCGTTACGCCTGCTGCTGTACAGTTGGTCATGA
TTACAATTCGAAAGAATGCACAAACTAAAAAAATTGCATAA

Upstream 100 bases:

>100_bases
GAACTATGAATTTTGTATCAATAATTTTGTAATAACATGCATGATAGTTGCATGAACTTTGCTATAATGTTCCGTCTTTT
TTTTCTGGTGTTTTTTTGCC

Downstream 100 bases:

>100_bases
TTGATTCTGTATAGAAAGCCCAGTATTTACTGGGCTTTTTTAATGCAATGAAAATAAATATCTAAATTTTAAGTAAGAAG
AAAAACAGAATTGCGTTGCA

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 626; Mature: 626

Protein sequence:

>626_residues
MHYPKVYDVIVIGGGHAGTEAALAAARMGRQTLLLTHNIETLGQMSCNPAIGGIGKSHLVREIDALGGAMALAADKGGIQ
FRILNSRKGAAVRATRAQADRVRYKAAIRHTLENQANLDIFQQAADDLIVEGDTVKGVVTQMGIRFDTKTVVLTTGTFLG
GVIHIGLEKSSGGRAGDPPSIALSHRLRELNLPVGRLKTGTPPRIDARSVDFSVMTPQPGDFPSPVMSFMGDVSMHPEQV
SCYITHTNEKTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFADKDSHQVFLEPEGLDTHELYPNGISTSLPFDV
QFELVRSIRGMENAHILRPGYAIEYDYFNPQALKFTLETKAINNLYFAGQINGTTGYEEAGAQGLLAGLNAARRAWDQEQ
WTPKRDQAYMGVLVDDLITLGTKEPYRMFTSRAEYRLMLREDNADQRLTPVGREMGLVDDVRWAAYCEKMEAVETETARL
AHLWAAPNNPMGKQFVEMTGADLSKECSAIDLLKRPNINFTQIAELTGSQVSTQVGDQIEIAVKYEGYINRQHEDVAQLK
RLEETKIPADFDYDIVSGLSREITQKLKTVRPETLAQAHRIPGVTPAAVQLVMITIRKNAQTKKIA

Sequences:

>Translated_626_residues
MHYPKVYDVIVIGGGHAGTEAALAAARMGRQTLLLTHNIETLGQMSCNPAIGGIGKSHLVREIDALGGAMALAADKGGIQ
FRILNSRKGAAVRATRAQADRVRYKAAIRHTLENQANLDIFQQAADDLIVEGDTVKGVVTQMGIRFDTKTVVLTTGTFLG
GVIHIGLEKSSGGRAGDPPSIALSHRLRELNLPVGRLKTGTPPRIDARSVDFSVMTPQPGDFPSPVMSFMGDVSMHPEQV
SCYITHTNEKTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFADKDSHQVFLEPEGLDTHELYPNGISTSLPFDV
QFELVRSIRGMENAHILRPGYAIEYDYFNPQALKFTLETKAINNLYFAGQINGTTGYEEAGAQGLLAGLNAARRAWDQEQ
WTPKRDQAYMGVLVDDLITLGTKEPYRMFTSRAEYRLMLREDNADQRLTPVGREMGLVDDVRWAAYCEKMEAVETETARL
AHLWAAPNNPMGKQFVEMTGADLSKECSAIDLLKRPNINFTQIAELTGSQVSTQVGDQIEIAVKYEGYINRQHEDVAQLK
RLEETKIPADFDYDIVSGLSREITQKLKTVRPETLAQAHRIPGVTPAAVQLVMITIRKNAQTKKIA
>Mature_626_residues
MHYPKVYDVIVIGGGHAGTEAALAAARMGRQTLLLTHNIETLGQMSCNPAIGGIGKSHLVREIDALGGAMALAADKGGIQ
FRILNSRKGAAVRATRAQADRVRYKAAIRHTLENQANLDIFQQAADDLIVEGDTVKGVVTQMGIRFDTKTVVLTTGTFLG
GVIHIGLEKSSGGRAGDPPSIALSHRLRELNLPVGRLKTGTPPRIDARSVDFSVMTPQPGDFPSPVMSFMGDVSMHPEQV
SCYITHTNEKTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFADKDSHQVFLEPEGLDTHELYPNGISTSLPFDV
QFELVRSIRGMENAHILRPGYAIEYDYFNPQALKFTLETKAINNLYFAGQINGTTGYEEAGAQGLLAGLNAARRAWDQEQ
WTPKRDQAYMGVLVDDLITLGTKEPYRMFTSRAEYRLMLREDNADQRLTPVGREMGLVDDVRWAAYCEKMEAVETETARL
AHLWAAPNNPMGKQFVEMTGADLSKECSAIDLLKRPNINFTQIAELTGSQVSTQVGDQIEIAVKYEGYINRQHEDVAQLK
RLEETKIPADFDYDIVSGLSREITQKLKTVRPETLAQAHRIPGVTPAAVQLVMITIRKNAQTKKIA

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=641, Percent_Identity=43.0577223088924, Blast_Score=483, Evalue=1e-136,
Organism=Homo sapiens, GI19882217, Length=666, Percent_Identity=41.4414414414414, Blast_Score=469, Evalue=1e-132,
Organism=Homo sapiens, GI183227703, Length=681, Percent_Identity=40.5286343612335, Blast_Score=464, Evalue=1e-130,
Organism=Escherichia coli, GI2367273, Length=629, Percent_Identity=66.2957074721781, Blast_Score=854, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17534255, Length=628, Percent_Identity=40.6050955414013, Blast_Score=444, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6321202, Length=624, Percent_Identity=43.1089743589744, Blast_Score=479, Evalue=1e-136,
Organism=Drosophila melanogaster, GI24658174, Length=637, Percent_Identity=46.7817896389325, Blast_Score=510, Evalue=1e-144,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_ACIAD (Q6F9Q1)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047035.1
- ProteinModelPortal:   Q6F9Q1
- SMR:   Q6F9Q1
- STRING:   Q6F9Q1
- GeneID:   2881134
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2440
- NMPDR:   fig|62977.3.peg.2044
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- PhylomeDB:   Q6F9Q1
- ProtClustDB:   PRK05192
- BioCyc:   ASP62977:ACIAD2440-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 69039; Mature: 69039

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYPKVYDVIVIGGGHAGTEAALAAARMGRQTLLLTHNIETLGQMSCNPAIGGIGKSHLV
CCCCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEEEECHHHHHCCCCCCCCCCCCHHHHH
REIDALGGAMALAADKGGIQFRILNSRKGAAVRATRAQADRVRYKAAIRHTLENQANLDI
HHHHHCCCEEEEEECCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCHHH
FQQAADDLIVEGDTVKGVVTQMGIRFDTKTVVLTTGTFLGGVIHIGLEKSSGGRAGDPPS
HHHHHCCEEECCCCHHHHHHHHCEEECCCEEEEECCHHHCCEEEEEEECCCCCCCCCCCC
IALSHRLRELNLPVGRLKTGTPPRIDARSVDFSVMTPQPGDFPSPVMSFMGDVSMHPEQV
HHHHHHHHHHCCCHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCEE
SCYITHTNEKTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFADKDSHQVFLEPE
EEEEEECCCHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECCC
GLDTHELYPNGISTSLPFDVQFELVRSIRGMENAHILRPGYAIEYDYFNPQALKFTLETK
CCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCEEEEECCCCCCEEEEEEEEE
AINNLYFAGQINGTTGYEEAGAQGLLAGLNAARRAWDQEQWTPKRDQAYMGVLVDDLITL
ECCCEEEEEEECCCCCCHHCCCHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHC
GTKEPYRMFTSRAEYRLMLREDNADQRLTPVGREMGLVDDVRWAAYCEKMEAVETETARL
CCCCHHHHHHCCCCEEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHE
AHLWAAPNNPMGKQFVEMTGADLSKECSAIDLLKRPNINFTQIAELTGSQVSTQVGDQIE
EEEECCCCCCCHHHHHHHCCCCHHHHCCHHHHHCCCCCCHHHHHHHCCCHHHHCCCCEEE
IAVKYEGYINRQHEDVAQLKRLEETKIPADFDYDIVSGLSREITQKLKTVRPETLAQAHR
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHC
IPGVTPAAVQLVMITIRKNAQTKKIA
CCCCCHHHEEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MHYPKVYDVIVIGGGHAGTEAALAAARMGRQTLLLTHNIETLGQMSCNPAIGGIGKSHLV
CCCCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEEEECHHHHHCCCCCCCCCCCCHHHHH
REIDALGGAMALAADKGGIQFRILNSRKGAAVRATRAQADRVRYKAAIRHTLENQANLDI
HHHHHCCCEEEEEECCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCHHH
FQQAADDLIVEGDTVKGVVTQMGIRFDTKTVVLTTGTFLGGVIHIGLEKSSGGRAGDPPS
HHHHHCCEEECCCCHHHHHHHHCEEECCCEEEEECCHHHCCEEEEEEECCCCCCCCCCCC
IALSHRLRELNLPVGRLKTGTPPRIDARSVDFSVMTPQPGDFPSPVMSFMGDVSMHPEQV
HHHHHHHHHHCCCHHCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCEE
SCYITHTNEKTHDIIRGGLDRSPMYTGVIEGVGPRYCPSIEDKIHRFADKDSHQVFLEPE
EEEEEECCCHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECCC
GLDTHELYPNGISTSLPFDVQFELVRSIRGMENAHILRPGYAIEYDYFNPQALKFTLETK
CCCHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEECCCEEEEECCCCCCEEEEEEEEE
AINNLYFAGQINGTTGYEEAGAQGLLAGLNAARRAWDQEQWTPKRDQAYMGVLVDDLITL
ECCCEEEEEEECCCCCCHHCCCHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHC
GTKEPYRMFTSRAEYRLMLREDNADQRLTPVGREMGLVDDVRWAAYCEKMEAVETETARL
CCCCHHHHHHCCCCEEEEEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHE
AHLWAAPNNPMGKQFVEMTGADLSKECSAIDLLKRPNINFTQIAELTGSQVSTQVGDQIE
EEEECCCCCCCHHHHHHHCCCCHHHHCCHHHHHCCCCCCHHHHHHHCCCHHHHCCCCEEE
IAVKYEGYINRQHEDVAQLKRLEETKIPADFDYDIVSGLSREITQKLKTVRPETLAQAHR
EEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHC
IPGVTPAAVQLVMITIRKNAQTKKIA
CCCCCHHHEEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA