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The map label for this gene is surA [H]

Identifier: 50085462

GI number: 50085462

Start: 2331020

End: 2332375

Strand: Direct

Name: surA [H]

Synonym: ACIAD2372

Alternate gene names: 50085462

Gene position: 2331020-2332375 (Clockwise)

Preceding gene: 50085461

Following gene: 50085467

Centisome position: 64.78

GC content: 42.33

Gene sequence:

>1356_bases
TTGGACACAACGTTAATGAAGACAAAGTATCTTAAACAGTTTTTTAAAACAACCGCACTTGCTCTGGTTGTTTCTTCATC
AATGCAAAGTTTTGCGGCACCTACCGACGAAGTAGTCGCAATTGTGGACAATAGCGTTATTTTAAAAAGTGACCTAGAAC
AAGGTGTGGCTGAAGCTCAACACCAATTGGAAGCTCAAAAGAAAACAGTTCCACCATTAAATTATCTACAGCTTCAAGTC
CTAGATCAGCTCATTTTAAGACAGGCTCAACTTGAGCAAGTAAAACGTTATGGCATTAAACCAGACGAAAACACCTTAAA
TGATGCTGTTTTAAAAGTTGCTAGCCAATCTGGTATTAAGTCATTGAGTGCTTTCCAGCAAAAACTTGATGCAATCGCGC
CTGGTACTTATGCTTCTTTACGTAATCGTATTGGTGAAGATTTGGCAATCAACCGTTTACGCCAACAGCAAGTTATGTCG
CGTATCAAAATTAGTGATCAGGATGTTGCCAATTTCCTTAAATCACCACAAGGTCAGGCGATGCTAGGAAGTCAGGTTCA
TGTGATTCATGCACGTATTTCTGCCCAATCAGATGTTGACCCGCAACAGCTTCAAAGCGTAGCACAGCAAGTTAAACAAG
CATTGAACGAAAGTAATGACATTACTGCGATCAGCAAAAAATTCTCGACGAAAGATATTAAAGTTGAGGGTGCTGATATG
GGATATCGCGATCTTGCAGAGTTACCTTCTGAACTTGCAGCACGAGTCAGTCCATTGCAAGCTGGCCAGACAACCGATCT
TATTAATGTGCGTGATGGTATTCATGTACTCAAGCTGATTGAACGTAAAAATAGCGAACAAAAAGCAATTGTGACACAAT
ATCAAACTCGTCATATTTTGATTCAGCCATCAGAAGTGATGAGCGCAGAAATGGCCAAGCAAACCATCGATAGTATTTAC
AATCGTTTAAAAGCTGGCGAGGACTTTACTACCCTTGCTGCGACTTATTCTGCCGATACTGGCTCAGCACGTGATGGCGG
AAGTTTAGGCTGGGTAACGCCTGGCTCTATGGTGCCAGAGTTTGAAAGCAAAATGAAGAATACGCCTGTGGGACAAATTA
GTGAACCATTCCAGACTCAGTTTGGCTGGCATATTCTGCAAGTGACTGCGACACGTGAAAAAGACATGACACATGAGTAT
CAGGAACGCATGGCTCGTCAGGTATTAGGCGAACGTCAATTTGATAGCGAACTTGATAGCTGGTTGAGAGAAGTACGTGC
TCATGCTTTTGTTCAAATCAAAGAGCCACAACTTGACTCTAAAGCACAGCAGAATGCTACGCCTACCACGCCGTGA

Upstream 100 bases:

>100_bases
TGATGGCGGAAATCACATTTAAAGGACTAGGCGGCTTAAATAACAAGTTGGCTTCTTTACTGGAAAATCGCGTTTTAGGC
TTTAAAGAAATTAATCAATC

Downstream 100 bases:

>100_bases
TTTAAGCCATCGAATTAAGATACATAAACCAGCCAAATCTGAACTGCACCCTTCAAATTAGACTAAAAGTGTCCAACTTT
CGGGGTGCAGTTCAATCCAG

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MDTTLMKTKYLKQFFKTTALALVVSSSMQSFAAPTDEVVAIVDNSVILKSDLEQGVAEAQHQLEAQKKTVPPLNYLQLQV
LDQLILRQAQLEQVKRYGIKPDENTLNDAVLKVASQSGIKSLSAFQQKLDAIAPGTYASLRNRIGEDLAINRLRQQQVMS
RIKISDQDVANFLKSPQGQAMLGSQVHVIHARISAQSDVDPQQLQSVAQQVKQALNESNDITAISKKFSTKDIKVEGADM
GYRDLAELPSELAARVSPLQAGQTTDLINVRDGIHVLKLIERKNSEQKAIVTQYQTRHILIQPSEVMSAEMAKQTIDSIY
NRLKAGEDFTTLAATYSADTGSARDGGSLGWVTPGSMVPEFESKMKNTPVGQISEPFQTQFGWHILQVTATREKDMTHEY
QERMARQVLGERQFDSELDSWLREVRAHAFVQIKEPQLDSKAQQNATPTTP

Sequences:

>Translated_451_residues
MDTTLMKTKYLKQFFKTTALALVVSSSMQSFAAPTDEVVAIVDNSVILKSDLEQGVAEAQHQLEAQKKTVPPLNYLQLQV
LDQLILRQAQLEQVKRYGIKPDENTLNDAVLKVASQSGIKSLSAFQQKLDAIAPGTYASLRNRIGEDLAINRLRQQQVMS
RIKISDQDVANFLKSPQGQAMLGSQVHVIHARISAQSDVDPQQLQSVAQQVKQALNESNDITAISKKFSTKDIKVEGADM
GYRDLAELPSELAARVSPLQAGQTTDLINVRDGIHVLKLIERKNSEQKAIVTQYQTRHILIQPSEVMSAEMAKQTIDSIY
NRLKAGEDFTTLAATYSADTGSARDGGSLGWVTPGSMVPEFESKMKNTPVGQISEPFQTQFGWHILQVTATREKDMTHEY
QERMARQVLGERQFDSELDSWLREVRAHAFVQIKEPQLDSKAQQNATPTTP
>Mature_451_residues
MDTTLMKTKYLKQFFKTTALALVVSSSMQSFAAPTDEVVAIVDNSVILKSDLEQGVAEAQHQLEAQKKTVPPLNYLQLQV
LDQLILRQAQLEQVKRYGIKPDENTLNDAVLKVASQSGIKSLSAFQQKLDAIAPGTYASLRNRIGEDLAINRLRQQQVMS
RIKISDQDVANFLKSPQGQAMLGSQVHVIHARISAQSDVDPQQLQSVAQQVKQALNESNDITAISKKFSTKDIKVEGADM
GYRDLAELPSELAARVSPLQAGQTTDLINVRDGIHVLKLIERKNSEQKAIVTQYQTRHILIQPSEVMSAEMAKQTIDSIY
NRLKAGEDFTTLAATYSADTGSARDGGSLGWVTPGSMVPEFESKMKNTPVGQISEPFQTQFGWHILQVTATREKDMTHEY
QERMARQVLGERQFDSELDSWLREVRAHAFVQIKEPQLDSKAQQNATPTTP

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=426, Percent_Identity=29.5774647887324, Blast_Score=172, Evalue=5e-44,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 50163; Mature: 50163

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTTLMKTKYLKQFFKTTALALVVSSSMQSFAAPTDEVVAIVDNSVILKSDLEQGVAEAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHHHHHHHHHHH
HQLEAQKKTVPPLNYLQLQVLDQLILRQAQLEQVKRYGIKPDENTLNDAVLKVASQSGIK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
SLSAFQQKLDAIAPGTYASLRNRIGEDLAINRLRQQQVMSRIKISDQDVANFLKSPQGQA
HHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCE
MLGSQVHVIHARISAQSDVDPQQLQSVAQQVKQALNESNDITAISKKFSTKDIKVEGADM
ECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEECCCC
GYRDLAELPSELAARVSPLQAGQTTDLINVRDGIHVLKLIERKNSEQKAIVTQYQTRHIL
CHHHHHHHHHHHHHHHCHHCCCCCCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEE
IQPSEVMSAEMAKQTIDSIYNRLKAGEDFTTLAATYSADTGSARDGGSLGWVTPGSMVPE
ECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCH
FESKMKNTPVGQISEPFQTQFGWHILQVTATREKDMTHEYQERMARQVLGERQFDSELDS
HHHHHCCCCCCCCCCCHHHHCCEEEEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
WLREVRAHAFVQIKEPQLDSKAQQNATPTTP
HHHHHHHHHEEEEECCCCCCHHHCCCCCCCC
>Mature Secondary Structure
MDTTLMKTKYLKQFFKTTALALVVSSSMQSFAAPTDEVVAIVDNSVILKSDLEQGVAEAQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCHHHHHHHHHHHHHH
HQLEAQKKTVPPLNYLQLQVLDQLILRQAQLEQVKRYGIKPDENTLNDAVLKVASQSGIK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
SLSAFQQKLDAIAPGTYASLRNRIGEDLAINRLRQQQVMSRIKISDQDVANFLKSPQGQA
HHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCE
MLGSQVHVIHARISAQSDVDPQQLQSVAQQVKQALNESNDITAISKKFSTKDIKVEGADM
ECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEECCCC
GYRDLAELPSELAARVSPLQAGQTTDLINVRDGIHVLKLIERKNSEQKAIVTQYQTRHIL
CHHHHHHHHHHHHHHHCHHCCCCCCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEE
IQPSEVMSAEMAKQTIDSIYNRLKAGEDFTTLAATYSADTGSARDGGSLGWVTPGSMVPE
ECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCH
FESKMKNTPVGQISEPFQTQFGWHILQVTATREKDMTHEYQERMARQVLGERQFDSELDS
HHHHHCCCCCCCCCCCHHHHCCEEEEEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
WLREVRAHAFVQIKEPQLDSKAQQNATPTTP
HHHHHHHHHEEEEECCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA