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The map label for this gene is phbC [H]

Identifier: 50085410

GI number: 50085410

Start: 2280314

End: 2281417

Strand: Direct

Name: phbC [H]

Synonym: ACIAD2315

Alternate gene names: 50085410

Gene position: 2280314-2281417 (Clockwise)

Preceding gene: 50085401

Following gene: 50085411

Centisome position: 63.37

GC content: 38.32

Gene sequence:

>1104_bases
ATGCAAAGAATGGAGTCAATCAAATCACTTATCCATCATCAGCAAATCAAACTCAAACATCTTTCAGCGCGTATTTTTAA
TGAAAAATCACTGGTTTTATCACAAACTACTCCTTATGAAGTAATTGCTGAATTTGATCAGACCAAGATTCGTTATTATG
CAGCACAACAAAGGCTTTATAAAGAACCTTTGGTCTTTGTCGCCCCGCTTGCCATTAACATGGACATTTATGATCTGTAC
CCTTATCGCTCGCTGATTCAATATTTTCAAGCGCAAGGTTTTGATGTTTATCTGATCGACTGGGGACGTTTGACTTATCA
AGATCGACATCTCAACTTTTTGTCATTTATTAGAAAAGCCCTTCCTGAATATATTCAAGTGATTCGTACACATTCACAAA
GTGATAAGATTTCTTTGCATGGCTGGAGCATGGCAGGTATTTTTGTCTTATTATACAGCGCGCTCAATCAACCGAATCAT
GTTAAAAATCTCATTGTGTTGGGTAGCCCAATTGATAGCTATGCATCTGGGCGAATTGGTAAACTTTATCAATTTGTGCA
TAAAAGCATTGCGAGTAACAAAAAACTTCAAACTCGACTTTATTCTGGTCTTCCTAAACGCCTCATTCATACACCCGGTA
TTCTCAATGCGTTAGGTTTCAAAATTCTTGATCCTAAAGGCTGGATAGATGGACATATTCAACTTTTGAAAAACCTTGAA
AACAAAAAACTGGTGCAGGAGCACGCAACTTTAGGCCACTTTCTCAATAATATGATCGATTATCCCGCAGGCATTAATCA
AGATATGTTATTTAATGTCTGGCTGCAAAATCCACTTAAACATGGTGCAATTCGCCTACAGGATCAAGTGATTGAATTAA
AAAATATTCAATCTTCTTTGTTGATTGGTGCAGGTCGTAGTGATCAGCTTGTGACAGCAGATGCAGTAAAACCTTTGACG
CAATTGACAAGCAGTAGTGATGTCACGTTTACTCTTATCCCTGGCGGTCACTTAGGGCTAATGTCGAGTCAAGCCAGTTC
TGAAGAATTTTGGCCGATGTTTAAGCATTGGTTGGCACAACGTTCAACACAAATTCAAGGGTAG

Upstream 100 bases:

>100_bases
AAAAACTGCCAACATTTTGAGCGTGTACGGTATTTAAGGTCAAGGTAAAAGATAAAATTATCGCTTAGACTTCAATCAAA
CTTTTTCGGATCTTAGAAAT

Downstream 100 bases:

>100_bases
ATTATGATTCAATCAGTTGCATTTATTGGCTTGGGCGCGATGGGCTATCGTATGGCATCGCATTTACCGCGGCACTTCGA
TACAGTTTATGTCTGGAATC

Product: poly(R)-hydroxyalkanoic acid synthase (PHA)

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MQRMESIKSLIHHQQIKLKHLSARIFNEKSLVLSQTTPYEVIAEFDQTKIRYYAAQQRLYKEPLVFVAPLAINMDIYDLY
PYRSLIQYFQAQGFDVYLIDWGRLTYQDRHLNFLSFIRKALPEYIQVIRTHSQSDKISLHGWSMAGIFVLLYSALNQPNH
VKNLIVLGSPIDSYASGRIGKLYQFVHKSIASNKKLQTRLYSGLPKRLIHTPGILNALGFKILDPKGWIDGHIQLLKNLE
NKKLVQEHATLGHFLNNMIDYPAGINQDMLFNVWLQNPLKHGAIRLQDQVIELKNIQSSLLIGAGRSDQLVTADAVKPLT
QLTSSSDVTFTLIPGGHLGLMSSQASSEEFWPMFKHWLAQRSTQIQG

Sequences:

>Translated_367_residues
MQRMESIKSLIHHQQIKLKHLSARIFNEKSLVLSQTTPYEVIAEFDQTKIRYYAAQQRLYKEPLVFVAPLAINMDIYDLY
PYRSLIQYFQAQGFDVYLIDWGRLTYQDRHLNFLSFIRKALPEYIQVIRTHSQSDKISLHGWSMAGIFVLLYSALNQPNH
VKNLIVLGSPIDSYASGRIGKLYQFVHKSIASNKKLQTRLYSGLPKRLIHTPGILNALGFKILDPKGWIDGHIQLLKNLE
NKKLVQEHATLGHFLNNMIDYPAGINQDMLFNVWLQNPLKHGAIRLQDQVIELKNIQSSLLIGAGRSDQLVTADAVKPLT
QLTSSSDVTFTLIPGGHLGLMSSQASSEEFWPMFKHWLAQRSTQIQG
>Mature_367_residues
MQRMESIKSLIHHQQIKLKHLSARIFNEKSLVLSQTTPYEVIAEFDQTKIRYYAAQQRLYKEPLVFVAPLAINMDIYDLY
PYRSLIQYFQAQGFDVYLIDWGRLTYQDRHLNFLSFIRKALPEYIQVIRTHSQSDKISLHGWSMAGIFVLLYSALNQPNH
VKNLIVLGSPIDSYASGRIGKLYQFVHKSIASNKKLQTRLYSGLPKRLIHTPGILNALGFKILDPKGWIDGHIQLLKNLE
NKKLVQEHATLGHFLNNMIDYPAGINQDMLFNVWLQNPLKHGAIRLQDQVIELKNIQSSLLIGAGRSDQLVTADAVKPLT
QLTSSSDVTFTLIPGGHLGLMSSQASSEEFWPMFKHWLAQRSTQIQG

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010125 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 41995; Mature: 41995

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRMESIKSLIHHQQIKLKHLSARIFNEKSLVLSQTTPYEVIAEFDQTKIRYYAAQQRLY
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
KEPLVFVAPLAINMDIYDLYPYRSLIQYFQAQGFDVYLIDWGRLTYQDRHLNFLSFIRKA
HCCCEEEEEEEECCCHHHHCCHHHHHHHHHHCCCEEEEEECCCEEECCCCHHHHHHHHHH
LPEYIQVIRTHSQSDKISLHGWSMAGIFVLLYSALNQPNHVKNLIVLGSPIDSYASGRIG
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHCEEEEECCCHHHHHCCCHH
KLYQFVHKSIASNKKLQTRLYSGLPKRLIHTPGILNALGFKILDPKGWIDGHIQLLKNLE
HHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCCCHHHHHCCEEECCCCCHHHHHHHHHCCH
NKKLVQEHATLGHFLNNMIDYPAGINQDMLFNVWLQNPLKHGAIRLQDQVIELKNIQSSL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHCCHHHCHHHHHHHHHHHHHHHHHH
LIGAGRSDQLVTADAVKPLTQLTSSSDVTFTLIPGGHLGLMSSQASSEEFWPMFKHWLAQ
EEECCCCCCEEEHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHH
RSTQIQG
HHHCCCC
>Mature Secondary Structure
MQRMESIKSLIHHQQIKLKHLSARIFNEKSLVLSQTTPYEVIAEFDQTKIRYYAAQQRLY
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
KEPLVFVAPLAINMDIYDLYPYRSLIQYFQAQGFDVYLIDWGRLTYQDRHLNFLSFIRKA
HCCCEEEEEEEECCCHHHHCCHHHHHHHHHHCCCEEEEEECCCEEECCCCHHHHHHHHHH
LPEYIQVIRTHSQSDKISLHGWSMAGIFVLLYSALNQPNHVKNLIVLGSPIDSYASGRIG
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHCEEEEECCCHHHHHCCCHH
KLYQFVHKSIASNKKLQTRLYSGLPKRLIHTPGILNALGFKILDPKGWIDGHIQLLKNLE
HHHHHHHHHHHCCHHHHHHHHHCCHHHHHCCCCHHHHHCCEEECCCCCHHHHHHHHHCCH
NKKLVQEHATLGHFLNNMIDYPAGINQDMLFNVWLQNPLKHGAIRLQDQVIELKNIQSSL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHCCHHHCHHHHHHHHHHHHHHHHHH
LIGAGRSDQLVTADAVKPLTQLTSSSDVTFTLIPGGHLGLMSSQASSEEFWPMFKHWLAQ
EEECCCCCCEEEHHHHHHHHHHCCCCCEEEEEECCCCEECCCCCCCCHHHHHHHHHHHHH
RSTQIQG
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1396692 [H]