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The map label for this gene is exoX [H]

Identifier: 50085361

GI number: 50085361

Start: 2229020

End: 2229718

Strand: Direct

Name: exoX [H]

Synonym: ACIAD2257

Alternate gene names: 50085361

Gene position: 2229020-2229718 (Clockwise)

Preceding gene: 50085353

Following gene: 50085362

Centisome position: 61.94

GC content: 39.34

Gene sequence:

>699_bases
TTGAATGTTATGAATGCCATTATTTTGGACACGGAAACTCACACATTAAATGGCAAGCCCATCGAGATTGCATATGCTCC
AATCGAAATACACAATGGAAAAATGACACTCGATAAAAGTCAGCTTTTCGACCAACTATATAGTGTGGAAGAACCAATTT
CCTATGCAGCAATGGCTGTGCATCACATTCTCGAATCTGATCTTCAGAACCAGCCACTTTACACAAGCTTTGAACTCCCA
ACATCGACTCAATATATCATTGGTCATAATATTGATTATGATATCAATGCGATTGCCCGTTGTGGCGTTGATGTTCGTCA
TATCAAGGCGATTTGTACTCTCGCGCTTGCTAGAAAAGTTTGGCCTGAATCAGAAGCACATAATATTTCGGCGTTAATTT
ATCAAATTTCCAAGGGCAGCCCTAAAGCTCGTGAATTACTCAAAGGTGCTCACCGTGCCGACGCAGATATTATATTAACG
GCCAACATTCTGATGCATATTGTGCATCATCTTGATATTTCGACTATCGAAGAACTCTACAATGCTTCCGAAGAAGCGCG
TATTCCTAAAATAATTAATTTTGGTAAACACAAAGGAACTGCCATCTCAGATTTGCCTCGTGACTATATACAATGGTTAT
TACGTCAAGATGATCTAGACAATTATCTCAAAAAGGCACTGGAAACATCACTGGTCTAA

Upstream 100 bases:

>100_bases
TCAAGAAAATAGTGCTTAGTTTAGCAGCAGCCTTTTATTGAATCACTTTGCACTAGATCAAGACAATGTTACATTTACAA
TGTAAGCAAAGAAAATCAGA

Downstream 100 bases:

>100_bases
AATATAGCTCTCACTGACTATTTCATCAATTTTGTAGTTTCTATCTTTGCCATATCCTTTAGTGTCTGCTGAATATTTTT
GGCAGACATGGCATTTTTTG

Product: DNA exonuclease X

Products: NA

Alternate protein names: Exodeoxyribonuclease X; Exo X; Exonuclease X [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNVMNAIILDTETHTLNGKPIEIAYAPIEIHNGKMTLDKSQLFDQLYSVEEPISYAAMAVHHILESDLQNQPLYTSFELP
TSTQYIIGHNIDYDINAIARCGVDVRHIKAICTLALARKVWPESEAHNISALIYQISKGSPKARELLKGAHRADADIILT
ANILMHIVHHLDISTIEELYNASEEARIPKIINFGKHKGTAISDLPRDYIQWLLRQDDLDNYLKKALETSLV

Sequences:

>Translated_232_residues
MNVMNAIILDTETHTLNGKPIEIAYAPIEIHNGKMTLDKSQLFDQLYSVEEPISYAAMAVHHILESDLQNQPLYTSFELP
TSTQYIIGHNIDYDINAIARCGVDVRHIKAICTLALARKVWPESEAHNISALIYQISKGSPKARELLKGAHRADADIILT
ANILMHIVHHLDISTIEELYNASEEARIPKIINFGKHKGTAISDLPRDYIQWLLRQDDLDNYLKKALETSLV
>Mature_232_residues
MNVMNAIILDTETHTLNGKPIEIAYAPIEIHNGKMTLDKSQLFDQLYSVEEPISYAAMAVHHILESDLQNQPLYTSFELP
TSTQYIIGHNIDYDINAIARCGVDVRHIKAICTLALARKVWPESEAHNISALIYQISKGSPKARELLKGAHRADADIILT
ANILMHIVHHLDISTIEELYNASEEARIPKIINFGKHKGTAISDLPRDYIQWLLRQDDLDNYLKKALETSLV

Specific function: Capable of degrading both single-strand and double- strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. May facilitate recombinational repair by pre- synaptic and/or post-synaptic DNA degradation [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788149, Length=216, Percent_Identity=29.1666666666667, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 26175; Mature: 26175

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVMNAIILDTETHTLNGKPIEIAYAPIEIHNGKMTLDKSQLFDQLYSVEEPISYAAMAV
CCCCCEEEEECCCCCCCCCEEEEEEEEEEEECCEEEECHHHHHHHHHHHHCHHHHHHHHH
HHILESDLQNQPLYTSFELPTSTQYIIGHNIDYDINAIARCGVDVRHIKAICTLALARKV
HHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
WPESEAHNISALIYQISKGSPKARELLKGAHRADADIILTANILMHIVHHLDISTIEELY
CCCCCCCCHHHHEEEECCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHH
NASEEARIPKIINFGKHKGTAISDLPRDYIQWLLRQDDLDNYLKKALETSLV
CCCCCCCCCHHHHCCCCCCCCHHHCCHHHHHHHHHHCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVMNAIILDTETHTLNGKPIEIAYAPIEIHNGKMTLDKSQLFDQLYSVEEPISYAAMAV
CCCCCEEEEECCCCCCCCCEEEEEEEEEEEECCEEEECHHHHHHHHHHHHCHHHHHHHHH
HHILESDLQNQPLYTSFELPTSTQYIIGHNIDYDINAIARCGVDVRHIKAICTLALARKV
HHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
WPESEAHNISALIYQISKGSPKARELLKGAHRADADIILTANILMHIVHHLDISTIEELY
CCCCCCCCHHHHEEEECCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCHHHHHHHH
NASEEARIPKIINFGKHKGTAISDLPRDYIQWLLRQDDLDNYLKKALETSLV
CCCCCCCCCHHHHCCCCCCCCHHHCCHHHHHHHHHHCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]