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The map label for this gene is hyu [H]

Identifier: 50085353

GI number: 50085353

Start: 2219472

End: 2220170

Strand: Direct

Name: hyu [H]

Synonym: ACIAD2248

Alternate gene names: 50085353

Gene position: 2219472-2220170 (Clockwise)

Preceding gene: 50085352

Following gene: 50085361

Centisome position: 61.68

GC content: 40.34

Gene sequence:

>699_bases
ATGCGGATACAAGTCATTAACCCCAACACCTGCATTGAAATGACTCATTCGATAGGTGAAAGTGCCAAAAAAGTTGCTGC
ACCAACCACCGAAATTATTGCTGTTTCTCCAGATCACGGTGTGCCATCCATTGAAGGCCATTATGATGAAGCCATTTCAG
CTTTAGGAACCTTGCAACTGATTAAAGAAGGTCGAGAAAATCAAGTTGATGGACATATTATTGCTTGTTTTGGTGATCCT
GCTTTACATGCTGCCCGCGAAATTGCAGATGCGCCTGTGATTGGTATTGCAGAAGCCGCATTTCATGTCGCAACATTGGT
TGCAACCAAATTTTCGATTGTGACCACTCTCTCTCGAACTCGAATTATTGCTGAACATTTACTGCATGAATATGGCTTTG
TACATAAATGTTCAAATATTCATTGTATCGATTTACCGGTACTTGAACTAGAAAGTAACACCGAAGAAACCTACCAAAAA
TTATTGGAACATTGTCTAAAAGCAAAACAACAAGACAATATTGGTGCAATTGTATTGGGATGTGGGGGTATGGCAAAACT
TGCCGAACGTGTCGCTCAAGAGATTGATATCCCTGTAATTGATGGCGTCACGGCTGCAGTGAAACTGCTTGAGGGTTTAC
ATGGACTAGGACTTAAAACCAGTAAATGGGGAGATTATAATTATCCAATTCGAAAATAA

Upstream 100 bases:

>100_bases
CTTATGATTGAAAAATTTGTGGAAGTCGCTTATCGCTTTAAATTTTATCGTTCAATACAGCTTATTTAGGCTTTTATTTT
AAATATCAAGGTTATGCATT

Downstream 100 bases:

>100_bases
CCAACAACTATTCAATATTGAATCATATAAAAAACCAGATACATCATCTGGTTTTTAAAGTGACTTTGTGAATACGATTC
AAAGTTGATCTATGGTGAAA

Product: hydantoin-racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MRIQVINPNTCIEMTHSIGESAKKVAAPTTEIIAVSPDHGVPSIEGHYDEAISALGTLQLIKEGRENQVDGHIIACFGDP
ALHAAREIADAPVIGIAEAAFHVATLVATKFSIVTTLSRTRIIAEHLLHEYGFVHKCSNIHCIDLPVLELESNTEETYQK
LLEHCLKAKQQDNIGAIVLGCGGMAKLAERVAQEIDIPVIDGVTAAVKLLEGLHGLGLKTSKWGDYNYPIRK

Sequences:

>Translated_232_residues
MRIQVINPNTCIEMTHSIGESAKKVAAPTTEIIAVSPDHGVPSIEGHYDEAISALGTLQLIKEGRENQVDGHIIACFGDP
ALHAAREIADAPVIGIAEAAFHVATLVATKFSIVTTLSRTRIIAEHLLHEYGFVHKCSNIHCIDLPVLELESNTEETYQK
LLEHCLKAKQQDNIGAIVLGCGGMAKLAERVAQEIDIPVIDGVTAAVKLLEGLHGLGLKTSKWGDYNYPIRK
>Mature_232_residues
MRIQVINPNTCIEMTHSIGESAKKVAAPTTEIIAVSPDHGVPSIEGHYDEAISALGTLQLIKEGRENQVDGHIIACFGDP
ALHAAREIADAPVIGIAEAAFHVATLVATKFSIVTTLSRTRIIAEHLLHEYGFVHKCSNIHCIDLPVLELESNTEETYQK
LLEHCLKAKQQDNIGAIVLGCGGMAKLAERVAQEIDIPVIDGVTAAVKLLEGLHGLGLKTSKWGDYNYPIRK

Specific function: Responsible for racemization of the D-5-substituted hydantoins to their corresponding L-amino acids [H]

COG id: COG4126

COG function: function code E; Hydantoin racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To yeast DCG1 and S.pombe SPAC1F7.10 [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322221, Length=213, Percent_Identity=28.169014084507, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015942 [H]

Pfam domain/function: PF01177 Asp_Glu_race [H]

EC number: =5.1.99.5 [H]

Molecular weight: Translated: 25082; Mature: 25082

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIQVINPNTCIEMTHSIGESAKKVAAPTTEIIAVSPDHGVPSIEGHYDEAISALGTLQL
CEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
IKEGRENQVDGHIIACFGDPALHAAREIADAPVIGIAEAAFHVATLVATKFSIVTTLSRT
HHCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIIAEHLLHEYGFVHKCSNIHCIDLPVLELESNTEETYQKLLEHCLKAKQQDNIGAIVLG
HHHHHHHHHHHCHHHHCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
CGGMAKLAERVAQEIDIPVIDGVTAAVKLLEGLHGLGLKTSKWGDYNYPIRK
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRIQVINPNTCIEMTHSIGESAKKVAAPTTEIIAVSPDHGVPSIEGHYDEAISALGTLQL
CEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
IKEGRENQVDGHIIACFGDPALHAAREIADAPVIGIAEAAFHVATLVATKFSIVTTLSRT
HHCCCCCCCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIIAEHLLHEYGFVHKCSNIHCIDLPVLELESNTEETYQKLLEHCLKAKQQDNIGAIVLG
HHHHHHHHHHHCHHHHCCCEEEEECCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEE
CGGMAKLAERVAQEIDIPVIDGVTAAVKLLEGLHGLGLKTSKWGDYNYPIRK
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339422 [H]