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The map label for this gene is qseC [H]

Identifier: 50085343

GI number: 50085343

Start: 2208598

End: 2209947

Strand: Reverse

Name: qseC [H]

Synonym: ACIAD2238

Alternate gene names: 50085343

Gene position: 2209947-2208598 (Counterclockwise)

Preceding gene: 50085344

Following gene: 50085342

Centisome position: 61.41

GC content: 36.15

Gene sequence:

>1350_bases
ATGACATCCTCAGTTTCATTACAAACTCGGCTCGTACGAGGGACACTGATCAGTAGCATGGTCGCTGGACTAATTGCTTT
TGTTTTACTGATAGCCATTACTGTAATTCATACTATGGATATCCAAGATCAGATTATGGATGAAGTTTCAGATTTACTTC
TTACTTCAGATGCCCATATACCTTCTGCTACAGATTTAAATGAATTGACTGAGGAATTTGATCTTCAATACAGCCTTGAT
TGGAAAGACAAAACATTGACGTATTCAGATCATCATGACGATATTGCTCATACACAGCATTTGGAAAAGGGTTATGGTTA
TTTTTTTCATCAGGGTGAGTTATGGCGAAGTTATGAAGCTGAAAAAAATAAATCCGAACTTAAGGTTATGGTTATACAGC
CTATTAAAGCCCGCTTTTCAGAAGTTTTTCAAAGTATTCTTTGGTATGCCGCAGGTTTGATATTTTTATGGTTGCTTCAA
TGGGGATTATTAAAATGGACAGTGAGACGGCAGCTTGCACCTTTGCATCATCTTTCTCATTTGATTGGAGAAAAGACGGT
TGATAATTTACAACCTATTCCAAATGAAGATTTAATATTTACAGAATTACAGCCAGTCATTTCTTCACTCAACCAATTAT
TGGTTCGACTTGAGCGAGCTTTGTCGGCGGAGCAGCGTTTTACAGCGGATGCTTCTCATGAGCTAAGATCGCCTCTGTCA
GCAATTCAGATGCGTTTAGAATTGATAAAAAGAAAATTTGCAGATATTGATTCATTAAATGCAGATATCGACAATATTCA
AATTGATGTAAAACGTAGTACACAGATTCTGGAAAATTTACTTTTACTTGCACGTCTTGATCCATCAAAAGCCAATGAAC
TTCCAAAAAAATCAATCGAAATGCTTGATTTGATTTCTGAAGTTAAAACAAATCTAATGCCATTCGCGATTCAAAAAAAT
ATAGTCATAACATCCCTATATTCACAGCAGAATGGTGTTGTAAATGCAAATCAGGAGTTGATATATAGTTGTATTAGAAA
CATCTTGGAAAATGCGATTCGTTATACTCCTGATCATGGGCAGGTATTTATTCATTTATTGAATCAAGATGCCCAATTGA
TTGTGAAAATTGAAGATACTGGAACGGGTGTAGAACCTGAAATACTTCCACAATTGGGGCAGCGTTTTTTTAGGGTGCTG
GGTACCAAGCAAAAAGGGACTGGACTAGGCTTATCGATTAGCCAAAAAATTCTTGAGTTACATTATGGTCAGTTAATATT
TGACCAGAGCAAATATGGTGGTTTATGTGTGGAAATTAGACTGCCTGTTGATCAATCGGTTTCAGATTAA

Upstream 100 bases:

>100_bases
AACGCGATTGAGGTTTTTATTTACCAGCTCAGGAAAAAAATAGGTACAAATTATATTAAGACAATTCGTGGCCTGGGTTA
TCGGATGAGCGAGTGAATAG

Downstream 100 bases:

>100_bases
AAAAACAGTATGGAATTCCATACTGTTTAGATTATTTTGACCACGATTATTATTGTTTTACAACGCGAGCAGTATCTTTT
ATTTCGTTAAAATAAGTCGG

Product: two-component system sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MTSSVSLQTRLVRGTLISSMVAGLIAFVLLIAITVIHTMDIQDQIMDEVSDLLLTSDAHIPSATDLNELTEEFDLQYSLD
WKDKTLTYSDHHDDIAHTQHLEKGYGYFFHQGELWRSYEAEKNKSELKVMVIQPIKARFSEVFQSILWYAAGLIFLWLLQ
WGLLKWTVRRQLAPLHHLSHLIGEKTVDNLQPIPNEDLIFTELQPVISSLNQLLVRLERALSAEQRFTADASHELRSPLS
AIQMRLELIKRKFADIDSLNADIDNIQIDVKRSTQILENLLLLARLDPSKANELPKKSIEMLDLISEVKTNLMPFAIQKN
IVITSLYSQQNGVVNANQELIYSCIRNILENAIRYTPDHGQVFIHLLNQDAQLIVKIEDTGTGVEPEILPQLGQRFFRVL
GTKQKGTGLGLSISQKILELHYGQLIFDQSKYGGLCVEIRLPVDQSVSD

Sequences:

>Translated_449_residues
MTSSVSLQTRLVRGTLISSMVAGLIAFVLLIAITVIHTMDIQDQIMDEVSDLLLTSDAHIPSATDLNELTEEFDLQYSLD
WKDKTLTYSDHHDDIAHTQHLEKGYGYFFHQGELWRSYEAEKNKSELKVMVIQPIKARFSEVFQSILWYAAGLIFLWLLQ
WGLLKWTVRRQLAPLHHLSHLIGEKTVDNLQPIPNEDLIFTELQPVISSLNQLLVRLERALSAEQRFTADASHELRSPLS
AIQMRLELIKRKFADIDSLNADIDNIQIDVKRSTQILENLLLLARLDPSKANELPKKSIEMLDLISEVKTNLMPFAIQKN
IVITSLYSQQNGVVNANQELIYSCIRNILENAIRYTPDHGQVFIHLLNQDAQLIVKIEDTGTGVEPEILPQLGQRFFRVL
GTKQKGTGLGLSISQKILELHYGQLIFDQSKYGGLCVEIRLPVDQSVSD
>Mature_448_residues
TSSVSLQTRLVRGTLISSMVAGLIAFVLLIAITVIHTMDIQDQIMDEVSDLLLTSDAHIPSATDLNELTEEFDLQYSLDW
KDKTLTYSDHHDDIAHTQHLEKGYGYFFHQGELWRSYEAEKNKSELKVMVIQPIKARFSEVFQSILWYAAGLIFLWLLQW
GLLKWTVRRQLAPLHHLSHLIGEKTVDNLQPIPNEDLIFTELQPVISSLNQLLVRLERALSAEQRFTADASHELRSPLSA
IQMRLELIKRKFADIDSLNADIDNIQIDVKRSTQILENLLLLARLDPSKANELPKKSIEMLDLISEVKTNLMPFAIQKNI
VITSLYSQQNGVVNANQELIYSCIRNILENAIRYTPDHGQVFIHLLNQDAQLIVKIEDTGTGVEPEILPQLGQRFFRVLG
TKQKGTGLGLSISQKILELHYGQLIFDQSKYGGLCVEIRLPVDQSVSD

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=360, Percent_Identity=29.7222222222222, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1790551, Length=300, Percent_Identity=31.6666666666667, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790346, Length=273, Percent_Identity=27.8388278388278, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790861, Length=300, Percent_Identity=27.6666666666667, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788393, Length=252, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786783, Length=300, Percent_Identity=25.6666666666667, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=30.4347826086957, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=25.2212389380531, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=25.1028806584362, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789808, Length=275, Percent_Identity=26.1818181818182, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788279, Length=233, Percent_Identity=30.0429184549356, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=25.1121076233184, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=239, Percent_Identity=26.3598326359833, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786912, Length=215, Percent_Identity=25.5813953488372, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787374, Length=334, Percent_Identity=22.7544910179641, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51044; Mature: 50912

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSVSLQTRLVRGTLISSMVAGLIAFVLLIAITVIHTMDIQDQIMDEVSDLLLTSDAHI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
PSATDLNELTEEFDLQYSLDWKDKTLTYSDHHDDIAHTQHLEKGYGYFFHQGELWRSYEA
CCCCCHHHHHHHHCCEEEECCCCCEEEECCCCCHHHHHHHHHHCCCEEEECCHHHHHHHC
EKNKSELKVMVIQPIKARFSEVFQSILWYAAGLIFLWLLQWGLLKWTVRRQLAPLHHLSH
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGEKTVDNLQPIPNEDLIFTELQPVISSLNQLLVRLERALSAEQRFTADASHELRSPLS
HHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHH
AIQMRLELIKRKFADIDSLNADIDNIQIDVKRSTQILENLLLLARLDPSKANELPKKSIE
HHHHHHHHHHHHHHCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHCCCHHHHH
MLDLISEVKTNLMPFAIQKNIVITSLYSQQNGVVNANQELIYSCIRNILENAIRYTPDHG
HHHHHHHHHHCCCCHHEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
QVFIHLLNQDAQLIVKIEDTGTGVEPEILPQLGQRFFRVLGTKQKGTGLGLSISQKILEL
CEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
HYGQLIFDQSKYGGLCVEIRLPVDQSVSD
HHCHHEEECCCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
TSSVSLQTRLVRGTLISSMVAGLIAFVLLIAITVIHTMDIQDQIMDEVSDLLLTSDAHI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
PSATDLNELTEEFDLQYSLDWKDKTLTYSDHHDDIAHTQHLEKGYGYFFHQGELWRSYEA
CCCCCHHHHHHHHCCEEEECCCCCEEEECCCCCHHHHHHHHHHCCCEEEECCHHHHHHHC
EKNKSELKVMVIQPIKARFSEVFQSILWYAAGLIFLWLLQWGLLKWTVRRQLAPLHHLSH
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIGEKTVDNLQPIPNEDLIFTELQPVISSLNQLLVRLERALSAEQRFTADASHELRSPLS
HHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHH
AIQMRLELIKRKFADIDSLNADIDNIQIDVKRSTQILENLLLLARLDPSKANELPKKSIE
HHHHHHHHHHHHHHCHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCCCHHHHCCCHHHHH
MLDLISEVKTNLMPFAIQKNIVITSLYSQQNGVVNANQELIYSCIRNILENAIRYTPDHG
HHHHHHHHHHCCCCHHEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
QVFIHLLNQDAQLIVKIEDTGTGVEPEILPQLGQRFFRVLGTKQKGTGLGLSISQKILEL
CEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
HYGQLIFDQSKYGGLCVEIRLPVDQSVSD
HHCHHEEECCCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]