Click here to switch to the map view.

The map label for this gene is qseB [H]

Identifier: 50085344

GI number: 50085344

Start: 2209952

End: 2210608

Strand: Reverse

Name: qseB [H]

Synonym: ACIAD2239

Alternate gene names: 50085344

Gene position: 2210608-2209952 (Counterclockwise)

Preceding gene: 50085345

Following gene: 50085343

Centisome position: 61.43

GC content: 41.1

Gene sequence:

>657_bases
ATGAGAATCTTGATCGCAGAAGATGACATTTCACAAGCAGAAAGTATCAAGTCTTGGTTGGAACTTGATGGCTATGTTGT
GGATTGGGTTGATCGTGGGGATTATGCGATTGCAGCGATCAAACAGCATGATTATGACTGTATTTTGCTTGATCGCGGCC
TTCCAAAATCGAGTGGAGATCAAGTATTGCTGACACTCAGAAAACATCAGTCCATGACGCCTGTCATTATGATTACAGCA
CGTGACAGTATTTCAGATCGAGTTACGGGATTAGATCTTGGGGCAAATGATTATCTGGTCAAGCCATTTAGTTTGGAAGA
ATTGTCTGCGCGAATTCGTAGTCATATTCGGTCAATGCAACAACAAGTAGATAGTCTTTTATGTTGGAAAAATATTGAAC
TGAATACACAGGATAAATGGGTGAAACTTTCAGGGGAGCTGGTTGAACTCACTGCAAAAGAATTTAAGGTGCTGCATAAA
ATGATGCAAAACCCAGAACGCGTAGTGACCCGTGAGCAACTTGAAAGTACGCTATATGCCTGGGGCGATGAAATAGAAAG
TAACGCGATTGAGGTTTTTATTTACCAGCTCAGGAAAAAAATAGGTACAAATTATATTAAGACAATTCGTGGCCTGGGTT
ATCGGATGAGCGAGTGA

Upstream 100 bases:

>100_bases
TGAACTGAATCAGTCTTGTAGCCTATCACCGTATATCCTGAAAAGGATATACGGTGAATTTTTTAGAATATTGATATAAC
CGCCAGAGAGTAAAATTAGA

Downstream 100 bases:

>100_bases
ATAGATGACATCCTCAGTTTCATTACAAACTCGGCTCGTACGAGGGACACTGATCAGTAGCATGGTCGCTGGACTAATTG
CTTTTGTTTTACTGATAGCC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MRILIAEDDISQAESIKSWLELDGYVVDWVDRGDYAIAAIKQHDYDCILLDRGLPKSSGDQVLLTLRKHQSMTPVIMITA
RDSISDRVTGLDLGANDYLVKPFSLEELSARIRSHIRSMQQQVDSLLCWKNIELNTQDKWVKLSGELVELTAKEFKVLHK
MMQNPERVVTREQLESTLYAWGDEIESNAIEVFIYQLRKKIGTNYIKTIRGLGYRMSE

Sequences:

>Translated_218_residues
MRILIAEDDISQAESIKSWLELDGYVVDWVDRGDYAIAAIKQHDYDCILLDRGLPKSSGDQVLLTLRKHQSMTPVIMITA
RDSISDRVTGLDLGANDYLVKPFSLEELSARIRSHIRSMQQQVDSLLCWKNIELNTQDKWVKLSGELVELTAKEFKVLHK
MMQNPERVVTREQLESTLYAWGDEIESNAIEVFIYQLRKKIGTNYIKTIRGLGYRMSE
>Mature_218_residues
MRILIAEDDISQAESIKSWLELDGYVVDWVDRGDYAIAAIKQHDYDCILLDRGLPKSSGDQVLLTLRKHQSMTPVIMITA
RDSISDRVTGLDLGANDYLVKPFSLEELSARIRSHIRSMQQQVDSLLCWKNIELNTQDKWVKLSGELVELTAKEFKVLHK
MMQNPERVVTREQLESTLYAWGDEIESNAIEVFIYQLRKKIGTNYIKTIRGLGYRMSE

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=39.4495412844037, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1790552, Length=216, Percent_Identity=39.3518518518519, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=37.6146788990826, Blast_Score=130, Evalue=5e-32,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=37.0535714285714, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=33.9366515837104, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=29.8165137614679, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=30, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=36.6812227074236, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790860, Length=219, Percent_Identity=28.7671232876712, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=31.25, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.0748898678414, Blast_Score=100, Evalue=5e-23,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=29.1479820627803, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=26.2008733624454, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1788550, Length=144, Percent_Identity=28.4722222222222, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=28.3842794759825, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25123; Mature: 25123

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIAEDDISQAESIKSWLELDGYVVDWVDRGDYAIAAIKQHDYDCILLDRGLPKSSGD
CEEEEECCCHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEECCCCCEEEEECCCCCCCCC
QVLLTLRKHQSMTPVIMITARDSISDRVTGLDLGANDYLVKPFSLEELSARIRSHIRSMQ
EEEEEEECCCCCCCEEEEEECCCCCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHHH
QQVDSLLCWKNIELNTQDKWVKLSGELVELTAKEFKVLHKMMQNPERVVTREQLESTLYA
HHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
WGDEIESNAIEVFIYQLRKKIGTNYIKTIRGLGYRMSE
CCCHHCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRILIAEDDISQAESIKSWLELDGYVVDWVDRGDYAIAAIKQHDYDCILLDRGLPKSSGD
CEEEEECCCHHHHHHHHHHHHHCCEEEEEEECCCEEEEEEECCCCCEEEEECCCCCCCCC
QVLLTLRKHQSMTPVIMITARDSISDRVTGLDLGANDYLVKPFSLEELSARIRSHIRSMQ
EEEEEEECCCCCCCEEEEEECCCCCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHHH
QQVDSLLCWKNIELNTQDKWVKLSGELVELTAKEFKVLHKMMQNPERVVTREQLESTLYA
HHHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
WGDEIESNAIEVFIYQLRKKIGTNYIKTIRGLGYRMSE
CCCHHCCCHHHHHHHHHHHHHCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]