Click here to switch to the map view.

The map label for this gene is yfbQ [H]

Identifier: 50085208

GI number: 50085208

Start: 2069321

End: 2070751

Strand: Direct

Name: yfbQ [H]

Synonym: ACIAD2087

Alternate gene names: 50085208

Gene position: 2069321-2070751 (Clockwise)

Preceding gene: 50085201

Following gene: 50085209

Centisome position: 57.5

GC content: 40.88

Gene sequence:

>1431_bases
ATGTCGCAGAAAAAAAGCGTTATTTTTAAAAACCTACTCCCTGTGATTAAACAATATCAACAGGCTGGATTCACGCATGA
AAAAATTGTTGCTTTACTCAAAGACCAACATGATCTTGATCTTGTAACAACTGAAACATTTAAAAGCTATTTATATCGTT
ATGCAAAAGTGACCCCCACTCCATCCGAGAGCCTCAAAATGACGAACACAATTCAAACCCCACGAGAAATTAAAAAATCT
TCTAAGCTCGAGCATGTATGCTACGACATTCGTGGACCTGTGTTACGAGCGGCCAATGAAATGGAAGAACAAGGTCATAA
AATTATTAAACTTAATATTGGCAACCCTGCGCCATTTGGTTTCGAAGCACCTCAAGAAATTATTAATGATGTCGCATTAA
ATCTACCTAACGCGATTGGTTACACTGACTCCAAAGGTATCTTCCCTGCACGTAAAGCCATTTGCCAGTATTATCAGCAA
AAAGGTATTCGCGATATGCACGTCAATGATGTGTATGTTGGAAACGGGGTATCCGAACTGATTGTCATGGCCATGCAAGG
TTTGCTAAATGATGGCGATGAAATGCTGGTTCCAATGCCAGATTATCCACTCTGGACAGCAGCAGTAAATTTATCTGGTG
GTACAGCAATTCACTATAAATGTGATGAAGAAAATAGCTGGTATCCAGATATTGTCGATATGGAAAGCAAAATAACGCCT
AATACTCGTGGTATTGTGGTGATTAATCCAAATAATCCAACAGGTTCGGTTTATCCAAGACACGTGCTCCAGCAAATTGT
AGCTTTAGCTAAAAAGCACGATCTGATTTTATTTGCCGATGAAATCTATGACAAGATTATTTACGATGGAATTGAACACG
TAGCACTTGCCTCTCTTGCAGGCGATCAACTCTGTATTTCCTTTAATGGTTTATCAAAATCTTATCGTGTTGCAGGTTAT
CGTTCAGGCTGGATGGCGATTACAGGTGATAAATCACGTGCTAAAGATTACATCGAAGGTCTGGATATGCTGGCATCCAT
GCGCCTATGTGCCAACCATCAAGCACAATATGCGATTCAAACGGCTTTAGGCGGTTATCAGTCGATTAATGACTTGATTC
GTCCAAGCGGACGTTTATACGAGCAACGCAATATTGCATGGGAAATGCTTAATGAAATACACGGCGTCAGTTGTGTAAAA
CCTGAGGGTGCCATGTATTGCTTTCCAAAACTAGATCCGAATATTTATCAGGTCGAGGATGATGAACAGTTGATGCTGGA
TTTCTTACGTGCAGAGAAAGTGCTTCTGGTACAAGGAACAGGATTTAACTGGCCAACGCATGATCACTTCCGCTTGGTCT
TCTTACCAGCAGAGAATGAGCTTCGAGAAGCAATTACACGATTATCACGCTTTCTCGCAACGCGCCGTTAA

Upstream 100 bases:

>100_bases
CAATAAACCAAAACCAGGTAAGCATTAATTATTATTAGCATGCTTCTACGTAAGCAAAAAAAATGTTATGCTTCTGGCTA
TTCTTGCTCAGGATTAAAAA

Downstream 100 bases:

>100_bases
TTAAGAAAATTTAAAGCAATGTCCTGCTTAGACATTGCTTTTTTCATTTTATTCGTTATACCCTCCCCACAAATAAAAGC
GCACCAAGATAAAGCAAAAC

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSQKKSVIFKNLLPVIKQYQQAGFTHEKIVALLKDQHDLDLVTTETFKSYLYRYAKVTPTPSESLKMTNTIQTPREIKKS
SKLEHVCYDIRGPVLRAANEMEEQGHKIIKLNIGNPAPFGFEAPQEIINDVALNLPNAIGYTDSKGIFPARKAICQYYQQ
KGIRDMHVNDVYVGNGVSELIVMAMQGLLNDGDEMLVPMPDYPLWTAAVNLSGGTAIHYKCDEENSWYPDIVDMESKITP
NTRGIVVINPNNPTGSVYPRHVLQQIVALAKKHDLILFADEIYDKIIYDGIEHVALASLAGDQLCISFNGLSKSYRVAGY
RSGWMAITGDKSRAKDYIEGLDMLASMRLCANHQAQYAIQTALGGYQSINDLIRPSGRLYEQRNIAWEMLNEIHGVSCVK
PEGAMYCFPKLDPNIYQVEDDEQLMLDFLRAEKVLLVQGTGFNWPTHDHFRLVFLPAENELREAITRLSRFLATRR

Sequences:

>Translated_476_residues
MSQKKSVIFKNLLPVIKQYQQAGFTHEKIVALLKDQHDLDLVTTETFKSYLYRYAKVTPTPSESLKMTNTIQTPREIKKS
SKLEHVCYDIRGPVLRAANEMEEQGHKIIKLNIGNPAPFGFEAPQEIINDVALNLPNAIGYTDSKGIFPARKAICQYYQQ
KGIRDMHVNDVYVGNGVSELIVMAMQGLLNDGDEMLVPMPDYPLWTAAVNLSGGTAIHYKCDEENSWYPDIVDMESKITP
NTRGIVVINPNNPTGSVYPRHVLQQIVALAKKHDLILFADEIYDKIIYDGIEHVALASLAGDQLCISFNGLSKSYRVAGY
RSGWMAITGDKSRAKDYIEGLDMLASMRLCANHQAQYAIQTALGGYQSINDLIRPSGRLYEQRNIAWEMLNEIHGVSCVK
PEGAMYCFPKLDPNIYQVEDDEQLMLDFLRAEKVLLVQGTGFNWPTHDHFRLVFLPAENELREAITRLSRFLATRR
>Mature_475_residues
SQKKSVIFKNLLPVIKQYQQAGFTHEKIVALLKDQHDLDLVTTETFKSYLYRYAKVTPTPSESLKMTNTIQTPREIKKSS
KLEHVCYDIRGPVLRAANEMEEQGHKIIKLNIGNPAPFGFEAPQEIINDVALNLPNAIGYTDSKGIFPARKAICQYYQQK
GIRDMHVNDVYVGNGVSELIVMAMQGLLNDGDEMLVPMPDYPLWTAAVNLSGGTAIHYKCDEENSWYPDIVDMESKITPN
TRGIVVINPNNPTGSVYPRHVLQQIVALAKKHDLILFADEIYDKIIYDGIEHVALASLAGDQLCISFNGLSKSYRVAGYR
SGWMAITGDKSRAKDYIEGLDMLASMRLCANHQAQYAIQTALGGYQSINDLIRPSGRLYEQRNIAWEMLNEIHGVSCVKP
EGAMYCFPKLDPNIYQVEDDEQLMLDFLRAEKVLLVQGTGFNWPTHDHFRLVFLPAENELREAITRLSRFLATRR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=27.8514588859416, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI19263340, Length=469, Percent_Identity=24.7334754797441, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI215599424, Length=379, Percent_Identity=25.5936675461741, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI4885351, Length=467, Percent_Identity=26.5524625267666, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI95147551, Length=264, Percent_Identity=24.2424242424242, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI169881279, Length=264, Percent_Identity=24.2424242424242, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI56713254, Length=184, Percent_Identity=27.7173913043478, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI56713256, Length=195, Percent_Identity=27.6923076923077, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI169881281, Length=118, Percent_Identity=29.6610169491525, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788627, Length=397, Percent_Identity=65.4911838790932, Blast_Score=570, Evalue=1e-164,
Organism=Escherichia coli, GI1788722, Length=402, Percent_Identity=24.8756218905473, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1786816, Length=384, Percent_Identity=22.3958333333333, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790797, Length=321, Percent_Identity=22.4299065420561, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=389, Percent_Identity=29.305912596401, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71981209, Length=458, Percent_Identity=23.7991266375546, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994472, Length=164, Percent_Identity=34.7560975609756, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71994476, Length=164, Percent_Identity=34.7560975609756, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17567369, Length=234, Percent_Identity=29.0598290598291, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=247, Percent_Identity=25.5060728744939, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=455, Percent_Identity=24.8351648351648, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6323118, Length=546, Percent_Identity=24.3589743589744, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=235, Percent_Identity=26.8085106382979, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=28.6472148541114, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24641770, Length=457, Percent_Identity=25.601750547046, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24641760, Length=457, Percent_Identity=25.601750547046, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24641768, Length=457, Percent_Identity=25.601750547046, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24641766, Length=457, Percent_Identity=25.601750547046, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24641764, Length=457, Percent_Identity=25.601750547046, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI45551451, Length=457, Percent_Identity=25.601750547046, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28573069, Length=167, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24646114, Length=167, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573067, Length=167, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573065, Length=167, Percent_Identity=25.748502994012, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 53795; Mature: 53664

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKKSVIFKNLLPVIKQYQQAGFTHEKIVALLKDQHDLDLVTTETFKSYLYRYAKVTPT
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCC
PSESLKMTNTIQTPREIKKSSKLEHVCYDIRGPVLRAANEMEEQGHKIIKLNIGNPAPFG
CHHHEEEHHCCCCHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCC
FEAPQEIINDVALNLPNAIGYTDSKGIFPARKAICQYYQQKGIRDMHVNDVYVGNGVSEL
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCEEEECCCHHHH
IVMAMQGLLNDGDEMLVPMPDYPLWTAAVNLSGGTAIHYKCDEENSWYPDIVDMESKITP
HHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCC
NTRGIVVINPNNPTGSVYPRHVLQQIVALAKKHDLILFADEIYDKIIYDGIEHVALASLA
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHC
GDQLCISFNGLSKSYRVAGYRSGWMAITGDKSRAKDYIEGLDMLASMRLCANHQAQYAIQ
CCEEEEEECCCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TALGGYQSINDLIRPSGRLYEQRNIAWEMLNEIHGVSCVKPEGAMYCFPKLDPNIYQVED
HHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCCCEEEECC
DEQLMLDFLRAEKVLLVQGTGFNWPTHDHFRLVFLPAENELREAITRLSRFLATRR
CHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQKKSVIFKNLLPVIKQYQQAGFTHEKIVALLKDQHDLDLVTTETFKSYLYRYAKVTPT
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCC
PSESLKMTNTIQTPREIKKSSKLEHVCYDIRGPVLRAANEMEEQGHKIIKLNIGNPAPFG
CHHHEEEHHCCCCHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCC
FEAPQEIINDVALNLPNAIGYTDSKGIFPARKAICQYYQQKGIRDMHVNDVYVGNGVSEL
CCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCEEEECCCHHHH
IVMAMQGLLNDGDEMLVPMPDYPLWTAAVNLSGGTAIHYKCDEENSWYPDIVDMESKITP
HHHHHHHHHCCCCCEEEECCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCC
NTRGIVVINPNNPTGSVYPRHVLQQIVALAKKHDLILFADEIYDKIIYDGIEHVALASLA
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHC
GDQLCISFNGLSKSYRVAGYRSGWMAITGDKSRAKDYIEGLDMLASMRLCANHQAQYAIQ
CCEEEEEECCCCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
TALGGYQSINDLIRPSGRLYEQRNIAWEMLNEIHGVSCVKPEGAMYCFPKLDPNIYQVED
HHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECCCCCEEEECC
DEQLMLDFLRAEKVLLVQGTGFNWPTHDHFRLVFLPAENELREAITRLSRFLATRR
CHHHHHHHHHCCEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]