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The map label for this gene is engD [H]

Identifier: 50085194

GI number: 50085194

Start: 2054819

End: 2055922

Strand: Direct

Name: engD [H]

Synonym: ACIAD2071

Alternate gene names: 50085194

Gene position: 2054819-2055922 (Clockwise)

Preceding gene: 50085193

Following gene: 50085195

Centisome position: 57.1

GC content: 43.12

Gene sequence:

>1104_bases
GTGAGTCATTTCATGGGTTTTAATTGCGGTATTGTCGGTCTGCCAAACGTTGGTAAATCAACTCTGTTTAATGCATTGAC
CAAAGCAGCGATTGCAGCAGAAAACTTTCCATTTTGTACCATTGAGCCAAATACTGGGATTGTTCCTGTACCTGATGCAC
GCTTAGACAAACTTGCAGCAATTGTAAAACCTCAGCGAATCTTACCTACCACAATGGAATTTGTGGATATTGCGGGTCTG
GTGGCTGGTGCATCGAAAGGTGAAGGTCTTGGTAACCAGTTTCTTGCCAATATTCGTGAAACCGATGCGATTGCCCACGT
GGTACGTTGTTTTGAAGATGAAAATGTCATTCACGTGAATGGCAAAATCGATCCACTTGATGATATCGCAACCATCAACA
CTGAGCTTGCATTGGCCGATTTAGATACTGTCGCAAAAGCTCTTCTCCGTTTGACCAAAGTTGCAAAAAGTGGTGATAAG
GAAGCTTTAGCAACCAAAGCCGTATTGGAAAAAATTCAGCCATTACTGGATGAAGGCAAACCAGCACGAGCAGCAGACCT
GAGCGATGATGAACGTAAATTGATTCGTGGCTTTGGTTTAATGACGTTAAAACCAACCATGTATATTGCAAATGTGGCAG
AAGACGGTTTTGAAAACAATCCACATTTAGATGCTGTAAAAAAATTAGCTGCCGAAGAAAATGCGATTGTCGTTCCACTC
TGTAACCAAATTGAAGCTGAAATTTCATTGCTGGAAGATGAAGATCGTGCAGAGTTTCTTGAAGCAATGGGAATGGAAGA
ACCAGGCCTAAACGTCGTGATCCGTGCTGGTTATGCGCTACTTGGCTTACAAACATACTTTACTGCAGGCGTGCAAGAAG
TTCGTGCTTGGACAGTAAAAGTAGGTGCAACTGCCCCACAAGCTGCTGGTGTGATTCATACCGATTTTGAGAAAGGCTTT
ATTCGCGCTGAATGTGTTGCATATGATGACTTTGTTCAATACAACGGCGAGGCAGGTGCAAAAGAAGCAGGTAAATGGCG
CTTAGAAGGCAAAACTTACGTGGTTCAAGATGGTGATGTGCTGCATTTCCGCTTTAACGTTTAA

Upstream 100 bases:

>100_bases
ACGTAAAATCTAAACTTCTTTATGATTCACACCATGCCATGACCTGACTTTGTCATGGCTTTCATGTAAAATCAGCCTCA
ATTTTTAATTTACATTTTTT

Downstream 100 bases:

>100_bases
AAAATTTAATAAAAAGGCCAGCGAAAGCTGGCTTTTTTATTAGAAATACAAAAAATTAAATAAAAAAGATAATAATAATG
ATTATCAATATATTTACATA

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSHFMGFNCGIVGLPNVGKSTLFNALTKAAIAAENFPFCTIEPNTGIVPVPDARLDKLAAIVKPQRILPTTMEFVDIAGL
VAGASKGEGLGNQFLANIRETDAIAHVVRCFEDENVIHVNGKIDPLDDIATINTELALADLDTVAKALLRLTKVAKSGDK
EALATKAVLEKIQPLLDEGKPARAADLSDDERKLIRGFGLMTLKPTMYIANVAEDGFENNPHLDAVKKLAAEENAIVVPL
CNQIEAEISLLEDEDRAEFLEAMGMEEPGLNVVIRAGYALLGLQTYFTAGVQEVRAWTVKVGATAPQAAGVIHTDFEKGF
IRAECVAYDDFVQYNGEAGAKEAGKWRLEGKTYVVQDGDVLHFRFNV

Sequences:

>Translated_367_residues
MSHFMGFNCGIVGLPNVGKSTLFNALTKAAIAAENFPFCTIEPNTGIVPVPDARLDKLAAIVKPQRILPTTMEFVDIAGL
VAGASKGEGLGNQFLANIRETDAIAHVVRCFEDENVIHVNGKIDPLDDIATINTELALADLDTVAKALLRLTKVAKSGDK
EALATKAVLEKIQPLLDEGKPARAADLSDDERKLIRGFGLMTLKPTMYIANVAEDGFENNPHLDAVKKLAAEENAIVVPL
CNQIEAEISLLEDEDRAEFLEAMGMEEPGLNVVIRAGYALLGLQTYFTAGVQEVRAWTVKVGATAPQAAGVIHTDFEKGF
IRAECVAYDDFVQYNGEAGAKEAGKWRLEGKTYVVQDGDVLHFRFNV
>Mature_366_residues
SHFMGFNCGIVGLPNVGKSTLFNALTKAAIAAENFPFCTIEPNTGIVPVPDARLDKLAAIVKPQRILPTTMEFVDIAGLV
AGASKGEGLGNQFLANIRETDAIAHVVRCFEDENVIHVNGKIDPLDDIATINTELALADLDTVAKALLRLTKVAKSGDKE
ALATKAVLEKIQPLLDEGKPARAADLSDDERKLIRGFGLMTLKPTMYIANVAEDGFENNPHLDAVKKLAAEENAIVVPLC
NQIEAEISLLEDEDRAEFLEAMGMEEPGLNVVIRAGYALLGLQTYFTAGVQEVRAWTVKVGATAPQAAGVIHTDFEKGFI
RAECVAYDDFVQYNGEAGAKEAGKWRLEGKTYVVQDGDVLHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=365, Percent_Identity=44.6575342465753, Blast_Score=315, Evalue=6e-86,
Organism=Homo sapiens, GI58761502, Length=225, Percent_Identity=39.5555555555556, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=70.7988980716253, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1789574, Length=139, Percent_Identity=28.7769784172662, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17509631, Length=362, Percent_Identity=40.8839779005525, Blast_Score=288, Evalue=3e-78,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=39.0243902439024, Blast_Score=249, Evalue=6e-67,
Organism=Saccharomyces cerevisiae, GI6321773, Length=391, Percent_Identity=31.9693094629156, Blast_Score=189, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6321649, Length=224, Percent_Identity=34.375, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24640873, Length=363, Percent_Identity=42.9752066115703, Blast_Score=294, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24640877, Length=363, Percent_Identity=42.9752066115703, Blast_Score=294, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24640875, Length=363, Percent_Identity=42.9752066115703, Blast_Score=294, Evalue=5e-80,
Organism=Drosophila melanogaster, GI24640879, Length=328, Percent_Identity=39.6341463414634, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24585318, Length=172, Percent_Identity=29.0697674418605, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39682; Mature: 39551

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHFMGFNCGIVGLPNVGKSTLFNALTKAAIAAENFPFCTIEPNTGIVPVPDARLDKLAA
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHHHHHH
IVKPQRILPTTMEFVDIAGLVAGASKGEGLGNQFLANIRETDAIAHVVRCFEDENVIHVN
HHCCCHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
GKIDPLDDIATINTELALADLDTVAKALLRLTKVAKSGDKEALATKAVLEKIQPLLDEGK
CCCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
PARAADLSDDERKLIRGFGLMTLKPTMYIANVAEDGFENNPHLDAVKKLAAEENAIVVPL
CCCCCCCCHHHHHHHHHCCCEEECCHHEEEEHHHCCCCCCCCHHHHHHHHCCCCEEEEEC
CNQIEAEISLLEDEDRAEFLEAMGMEEPGLNVVIRAGYALLGLQTYFTAGVQEVRAWTVK
CCCHHHHHHEECCCHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEE
VGATAPQAAGVIHTDFEKGFIRAECVAYDDFVQYNGEAGAKEAGKWRLEGKTYVVQDGDV
ECCCCCCCCCCEEECCCCCCEEEEEEEEHHHHHCCCCCCCCCCCCEEECCEEEEEECCCE
LHFRFNV
EEEEECC
>Mature Secondary Structure 
SHFMGFNCGIVGLPNVGKSTLFNALTKAAIAAENFPFCTIEPNTGIVPVPDARLDKLAA
CCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHHHHHH
IVKPQRILPTTMEFVDIAGLVAGASKGEGLGNQFLANIRETDAIAHVVRCFEDENVIHVN
HHCCCHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
GKIDPLDDIATINTELALADLDTVAKALLRLTKVAKSGDKEALATKAVLEKIQPLLDEGK
CCCCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
PARAADLSDDERKLIRGFGLMTLKPTMYIANVAEDGFENNPHLDAVKKLAAEENAIVVPL
CCCCCCCCHHHHHHHHHCCCEEECCHHEEEEHHHCCCCCCCCHHHHHHHHCCCCEEEEEC
CNQIEAEISLLEDEDRAEFLEAMGMEEPGLNVVIRAGYALLGLQTYFTAGVQEVRAWTVK
CCCHHHHHHEECCCHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEE
VGATAPQAAGVIHTDFEKGFIRAECVAYDDFVQYNGEAGAKEAGKWRLEGKTYVVQDGDV
ECCCCCCCCCCEEECCCCCCEEEEEEEEHHHHHCCCCCCCCCCCCEEECCEEEEEECCCE
LHFRFNV
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA