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The map label for this gene is soxA [H]

Identifier: 50085190

GI number: 50085190

Start: 2050737

End: 2052149

Strand: Direct

Name: soxA [H]

Synonym: ACIAD2066

Alternate gene names: 50085190

Gene position: 2050737-2052149 (Clockwise)

Preceding gene: 50085189

Following gene: 50085191

Centisome position: 56.99

GC content: 40.84

Gene sequence:

>1413_bases
ATGACAGAAACCACACAAAAGCACATTTTACTCAATGCTTTTGATATGAATAGTGTGGGACATATCAATCATGGCCTTTG
GACACATCCACGTGATGAATCACATCGTTTTAGTGAGTTAAGTTATTGGACCGATCTCGCAAAGACACTCGAAGCAGGTT
TATTTGATGGTTTATTTATTGCCGATATCACAGGTGTTTATGATGTCTATCAAAACAATATCGACCTGACTTTACGCGAA
TCTATTCAGTTACCTAGTCATGATCCGAGTACTCTTGTTTCTGCCATGGCGGCGGTCACACAACATTTAGGTTTTGGCAT
TACTGTCAATTTAAGTTACGAAACGCCCTATCAGTTTGCACGCCGTTTTGCATCTTTGGATCATCTGACTCAAGGACGTA
TTGGCTGGAATATCGTGACTGGTTATCTTGATAGTGCCGAGCGTCTTATTGGTCAATCTGGACTTAAAGATCATGATTTA
CGCTATGAACAGGCAGAAGAATTTTTACAGCTTTGCTATAAGTACTGGGAAGGTTCCTGGGAACATGATGCGGTAGAGAA
AGACAAACATCATCGTATTTTTACCAATCCATCCAAAGTACATGAAATACATCATGAAGGACGTTTTTATCAGAGCCATG
GTGTTTTTCAGGTATCGCCTTCGCGACAGCGCACCCCTGTCCTTTTTCAGGCAGGCGCCTCTACGCGGGGTATAAAGTTC
GCAACCTCACATGCTGAATGTATCTTTATTGGCGGCGATACTCCTGAAAAACTTCGCCAGCAAGTGATCAAAATTCGTGA
ACAAGCTGCTCAACAAGGTCGTAATCCTTCAGATATTAAAATCTTTGTTGGTATTACAGTAGTGACTGCTGAAACAACAC
AACGCGCACAACAGAAGCTTGAGGAATATCGCCATTATGCCAGTCCAGAAGCTGGACTTGCCCACTATGCCAGCTCAGTC
GGTATTGATTTATCGAAGTTTGCTGATGATGAAATCATCCCTTATCAAAAAAGTAACAGTATTGCTTCAGTGAATGAGAA
ATTCAGAGCACAGCAAATCAGCAAAAATGACTTAAAAAACCAGCATGTGCTTGGTGGTCGCTATCCACTCATTGTTGGAA
GTGGACATGACGTTGCTGAACAATTAATTCAGCTCATTGATAGCACAGGAATTGATGGATTTAACTTGACGCGTACGGTA
GCGCCTGAATCTCATCATGATTTTATTCGTTTTGTGATTCCAGAGCTACAACAACGTGGACGCTTCAAAACAGCTTACAA
AACTGGTTCTTTTCGTCAAAAAATTTCGGGATATGGTGACTTATTGCCTTTGACACATCCAGTCGAACAATATCGATGTT
CATCTTCTACATCTTCAATGCATTCATTTAAACACAAAAAAATTACAGCATAA

Upstream 100 bases:

>100_bases
CACGAGTACATACGCTGCATGATGCAGCACGCTGGAAATATTACTTTATTGGAAACTACGTATTAAACGATATATTTCCG
CCACGAAGAGGGACATTGTA

Downstream 100 bases:

>100_bases
TTCTTGGAGTCTTCGATGGCACAGTCATCTTCATCTAAAAAACTGATTATTTTTGGAACCTTATTTGTCATTCTCATCGT
TGGTTTGTTTATCTGGAATA

Product: monooxygenase

Products: an aldehyde; SO3; H2O; FMN [C]

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTETTQKHILLNAFDMNSVGHINHGLWTHPRDESHRFSELSYWTDLAKTLEAGLFDGLFIADITGVYDVYQNNIDLTLRE
SIQLPSHDPSTLVSAMAAVTQHLGFGITVNLSYETPYQFARRFASLDHLTQGRIGWNIVTGYLDSAERLIGQSGLKDHDL
RYEQAEEFLQLCYKYWEGSWEHDAVEKDKHHRIFTNPSKVHEIHHEGRFYQSHGVFQVSPSRQRTPVLFQAGASTRGIKF
ATSHAECIFIGGDTPEKLRQQVIKIREQAAQQGRNPSDIKIFVGITVVTAETTQRAQQKLEEYRHYASPEAGLAHYASSV
GIDLSKFADDEIIPYQKSNSIASVNEKFRAQQISKNDLKNQHVLGGRYPLIVGSGHDVAEQLIQLIDSTGIDGFNLTRTV
APESHHDFIRFVIPELQQRGRFKTAYKTGSFRQKISGYGDLLPLTHPVEQYRCSSSTSSMHSFKHKKITA

Sequences:

>Translated_470_residues
MTETTQKHILLNAFDMNSVGHINHGLWTHPRDESHRFSELSYWTDLAKTLEAGLFDGLFIADITGVYDVYQNNIDLTLRE
SIQLPSHDPSTLVSAMAAVTQHLGFGITVNLSYETPYQFARRFASLDHLTQGRIGWNIVTGYLDSAERLIGQSGLKDHDL
RYEQAEEFLQLCYKYWEGSWEHDAVEKDKHHRIFTNPSKVHEIHHEGRFYQSHGVFQVSPSRQRTPVLFQAGASTRGIKF
ATSHAECIFIGGDTPEKLRQQVIKIREQAAQQGRNPSDIKIFVGITVVTAETTQRAQQKLEEYRHYASPEAGLAHYASSV
GIDLSKFADDEIIPYQKSNSIASVNEKFRAQQISKNDLKNQHVLGGRYPLIVGSGHDVAEQLIQLIDSTGIDGFNLTRTV
APESHHDFIRFVIPELQQRGRFKTAYKTGSFRQKISGYGDLLPLTHPVEQYRCSSSTSSMHSFKHKKITA
>Mature_469_residues
TETTQKHILLNAFDMNSVGHINHGLWTHPRDESHRFSELSYWTDLAKTLEAGLFDGLFIADITGVYDVYQNNIDLTLRES
IQLPSHDPSTLVSAMAAVTQHLGFGITVNLSYETPYQFARRFASLDHLTQGRIGWNIVTGYLDSAERLIGQSGLKDHDLR
YEQAEEFLQLCYKYWEGSWEHDAVEKDKHHRIFTNPSKVHEIHHEGRFYQSHGVFQVSPSRQRTPVLFQAGASTRGIKFA
TSHAECIFIGGDTPEKLRQQVIKIREQAAQQGRNPSDIKIFVGITVVTAETTQRAQQKLEEYRHYASPEAGLAHYASSVG
IDLSKFADDEIIPYQKSNSIASVNEKFRAQQISKNDLKNQHVLGGRYPLIVGSGHDVAEQLIQLIDSTGIDGFNLTRTVA
PESHHDFIRFVIPELQQRGRFKTAYKTGSFRQKISGYGDLLPLTHPVEQYRCSSSTSSMHSFKHKKITA

Specific function: Part of a pathway to remove covalently bound sulfur from dibenzothiophene (DBT) without breaking carbon-carbon bonds. This enzyme metabolizes DBT-sulfone (DBTO2 or DBT 5,5-dioxide) to 2- hydroxybiphenyl (2-HBP) [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ntaA/snaA/soxA(dszA) monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1787166, Length=313, Percent_Identity=25.5591054313099, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR016215 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: 1.14.14.5 [C]

Molecular weight: Translated: 53213; Mature: 53082

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETTQKHILLNAFDMNSVGHINHGLWTHPRDESHRFSELSYWTDLAKTLEAGLFDGLFI
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
ADITGVYDVYQNNIDLTLRESIQLPSHDPSTLVSAMAAVTQHLGFGITVNLSYETPYQFA
HHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHH
RRFASLDHLTQGRIGWNIVTGYLDSAERLIGQSGLKDHDLRYEQAEEFLQLCYKYWEGSW
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
EHDAVEKDKHHRIFTNPSKVHEIHHEGRFYQSHGVFQVSPSRQRTPVLFQAGASTRGIKF
CCCCCCCCCCCEEECCHHHHHHHHHCCCEEECCCEEEECCCCCCCCEEEECCCCCCCEEE
ATSHAECIFIGGDTPEKLRQQVIKIREQAAQQGRNPSDIKIFVGITVVTAETTQRAQQKL
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECHHHHHHHHHH
EEYRHYASPEAGLAHYASSVGIDLSKFADDEIIPYQKSNSIASVNEKFRAQQISKNDLKN
HHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
QHVLGGRYPLIVGSGHDVAEQLIQLIDSTGIDGFNLTRTVAPESHHDFIRFVIPELQQRG
CCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCC
RFKTAYKTGSFRQKISGYGDLLPLTHPVEQYRCSSSTSSMHSFKHKKITA
CEEEHHCCCHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TETTQKHILLNAFDMNSVGHINHGLWTHPRDESHRFSELSYWTDLAKTLEAGLFDGLFI
CCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHH
ADITGVYDVYQNNIDLTLRESIQLPSHDPSTLVSAMAAVTQHLGFGITVNLSYETPYQFA
HHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHH
RRFASLDHLTQGRIGWNIVTGYLDSAERLIGQSGLKDHDLRYEQAEEFLQLCYKYWEGSW
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCC
EHDAVEKDKHHRIFTNPSKVHEIHHEGRFYQSHGVFQVSPSRQRTPVLFQAGASTRGIKF
CCCCCCCCCCCEEECCHHHHHHHHHCCCEEECCCEEEECCCCCCCCEEEECCCCCCCEEE
ATSHAECIFIGGDTPEKLRQQVIKIREQAAQQGRNPSDIKIFVGITVVTAETTQRAQQKL
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECHHHHHHHHHH
EEYRHYASPEAGLAHYASSVGIDLSKFADDEIIPYQKSNSIASVNEKFRAQQISKNDLKN
HHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
QHVLGGRYPLIVGSGHDVAEQLIQLIDSTGIDGFNLTRTVAPESHHDFIRFVIPELQQRG
CCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHCC
RFKTAYKTGSFRQKISGYGDLLPLTHPVEQYRCSSSTSSMHSFKHKKITA
CEEEHHCCCHHHHHHCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: an alkanesulfonate; O2; FMNH2 [C]

Specific reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + SO3 + H2O + FMN [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961424; 7574582 [H]