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The map label for this gene is galE [H]

Identifier: 50085032

GI number: 50085032

Start: 1883580

End: 1884584

Strand: Reverse

Name: galE [H]

Synonym: ACIAD1891

Alternate gene names: 50085032

Gene position: 1884584-1883580 (Counterclockwise)

Preceding gene: 50085037

Following gene: 50085031

Centisome position: 52.37

GC content: 37.51

Gene sequence:

>1005_bases
ATGATTTTAGTGACAGGTGGTTTAGGCTTTCTTGGGTCACATATTGCTTTGAGCTTACTTGCTCAAGGTCAAGAAGTTAT
TTTGGTTGATAATTTAGCAAATGCTTCACTACAGACACTGGAACGGCTTGAATACATATCTGGAATGTACATTCCCTTTG
TGAAAGTAGATGTACGAAACACGCCCGCCTTAAACAAGGTATTCGAGCAATATTCTATCGATGCTGTGATTCACACTGCC
AGCTTTAAAGCACTTGAAGAATCAAAACTAAAACCACTTGAATATTACAATGATAATGTCAGTTGTATTATGAGCTTGCT
ACGTTCAATGCAACGAACTGGTGTACGTAAACTTGTTCATTTATCAAGTTTAATGGTGTATGGAAAATCGAGTTCAAAAC
TTACCGAAGATGAGCCATTTGATACAGTTTATCCAAATCCCTATATCAAGTCTCAGCAAATGATCGAAGAAATTATCAGA
GATACTTTTAAGACAGATCATGAATGGAAAATTGCCATTCTAAGACTCTCTAACATTGCGGGTGCATTTGAGCATGGTGT
TTTAGGAGAAATGATCACGCAGTTACCTAAAAATATTATTCCGCTTGCAATGCAGGTTGCAGCAATGCAACGAGATTATC
TTGAATTACAGCGTCAAGCTGACACAACAGATCAAACCGTTGAACGTAGTTTTTTGCATGTGTTGGATGTATGTGAGGCG
GTGTTTGCAAGTTTGTATTGGTTAAATCAACAAGATCATTGTTGTGAATCATTTAATATTGCACACAATGAGGTAACCTC
TATACAACAGCTATTGGAAGTCATCAGTCAGGTGACGCAAACTCAGATTAATACTCATGATGCGATGTATCCAACCGAAG
AGCTGGCTCAGGTTGGTGCAAATATCGATAAGGCGAAACAAGTACTTAACTGGCAGCCAAAACGTACATTACAACAAATG
ATCGAACATCAATGGCAATTTTATCAAAATACCTTAAAAGGATAA

Upstream 100 bases:

>100_bases
GCTGAGGTAACTAATACTAAAGTGCTCATGGAAATTTCACTATGGACATGTCTCTGATAACAGATGGGTCATTTACACAT
TATAAAAAGGTAAGTATACA

Downstream 100 bases:

>100_bases
TAGGAATATTAAAAGGATAATAGGAATATTAAAATGATTCTTATTTACAAAATTGTTGTGCTTGATTAGTATCATCTCAC
TAGCCAAGTAATGATTACAA

Product: UDP-galactose 4-epimerase (GalE-like)

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MILVTGGLGFLGSHIALSLLAQGQEVILVDNLANASLQTLERLEYISGMYIPFVKVDVRNTPALNKVFEQYSIDAVIHTA
SFKALEESKLKPLEYYNDNVSCIMSLLRSMQRTGVRKLVHLSSLMVYGKSSSKLTEDEPFDTVYPNPYIKSQQMIEEIIR
DTFKTDHEWKIAILRLSNIAGAFEHGVLGEMITQLPKNIIPLAMQVAAMQRDYLELQRQADTTDQTVERSFLHVLDVCEA
VFASLYWLNQQDHCCESFNIAHNEVTSIQQLLEVISQVTQTQINTHDAMYPTEELAQVGANIDKAKQVLNWQPKRTLQQM
IEHQWQFYQNTLKG

Sequences:

>Translated_334_residues
MILVTGGLGFLGSHIALSLLAQGQEVILVDNLANASLQTLERLEYISGMYIPFVKVDVRNTPALNKVFEQYSIDAVIHTA
SFKALEESKLKPLEYYNDNVSCIMSLLRSMQRTGVRKLVHLSSLMVYGKSSSKLTEDEPFDTVYPNPYIKSQQMIEEIIR
DTFKTDHEWKIAILRLSNIAGAFEHGVLGEMITQLPKNIIPLAMQVAAMQRDYLELQRQADTTDQTVERSFLHVLDVCEA
VFASLYWLNQQDHCCESFNIAHNEVTSIQQLLEVISQVTQTQINTHDAMYPTEELAQVGANIDKAKQVLNWQPKRTLQQM
IEHQWQFYQNTLKG
>Mature_334_residues
MILVTGGLGFLGSHIALSLLAQGQEVILVDNLANASLQTLERLEYISGMYIPFVKVDVRNTPALNKVFEQYSIDAVIHTA
SFKALEESKLKPLEYYNDNVSCIMSLLRSMQRTGVRKLVHLSSLMVYGKSSSKLTEDEPFDTVYPNPYIKSQQMIEEIIR
DTFKTDHEWKIAILRLSNIAGAFEHGVLGEMITQLPKNIIPLAMQVAAMQRDYLELQRQADTTDQTVERSFLHVLDVCEA
VFASLYWLNQQDHCCESFNIAHNEVTSIQQLLEVISQVTQTQINTHDAMYPTEELAQVGANIDKAKQVLNWQPKRTLQQM
IEHQWQFYQNTLKG

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=346, Percent_Identity=33.8150289017341, Blast_Score=187, Evalue=8e-48,
Organism=Homo sapiens, GI56118217, Length=346, Percent_Identity=33.8150289017341, Blast_Score=187, Evalue=8e-48,
Organism=Homo sapiens, GI189083684, Length=346, Percent_Identity=33.8150289017341, Blast_Score=187, Evalue=8e-48,
Organism=Homo sapiens, GI7657641, Length=352, Percent_Identity=24.4318181818182, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1786974, Length=335, Percent_Identity=33.7313432835821, Blast_Score=198, Evalue=3e-52,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=25.3443526170799, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=342, Percent_Identity=31.2865497076023, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI71982038, Length=344, Percent_Identity=31.1046511627907, Blast_Score=178, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17568069, Length=250, Percent_Identity=29.2, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115532424, Length=339, Percent_Identity=24.4837758112094, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=337, Percent_Identity=31.4540059347181, Blast_Score=191, Evalue=1e-49,
Organism=Drosophila melanogaster, GI19923002, Length=335, Percent_Identity=31.3432835820896, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38055; Mature: 38055

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVTGGLGFLGSHIALSLLAQGQEVILVDNLANASLQTLERLEYISGMYIPFVKVDVRN
CEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCC
TPALNKVFEQYSIDAVIHTASFKALEESKLKPLEYYNDNVSCIMSLLRSMQRTGVRKLVH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LSSLMVYGKSSSKLTEDEPFDTVYPNPYIKSQQMIEEIIRDTFKTDHEWKIAILRLSNIA
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHH
GAFEHGVLGEMITQLPKNIIPLAMQVAAMQRDYLELQRQADTTDQTVERSFLHVLDVCEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VFASLYWLNQQDHCCESFNIAHNEVTSIQQLLEVISQVTQTQINTHDAMYPTEELAQVGA
HHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
NIDKAKQVLNWQPKRTLQQMIEHQWQFYQNTLKG
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILVTGGLGFLGSHIALSLLAQGQEVILVDNLANASLQTLERLEYISGMYIPFVKVDVRN
CEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCC
TPALNKVFEQYSIDAVIHTASFKALEESKLKPLEYYNDNVSCIMSLLRSMQRTGVRKLVH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
LSSLMVYGKSSSKLTEDEPFDTVYPNPYIKSQQMIEEIIRDTFKTDHEWKIAILRLSNIA
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEHHHHH
GAFEHGVLGEMITQLPKNIIPLAMQVAAMQRDYLELQRQADTTDQTVERSFLHVLDVCEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VFASLYWLNQQDHCCESFNIAHNEVTSIQQLLEVISQVTQTQINTHDAMYPTEELAQVGA
HHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCC
NIDKAKQVLNWQPKRTLQQMIEHQWQFYQNTLKG
CHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]