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The map label for this gene is sstT

Identifier: 50085010

GI number: 50085010

Start: 1860954

End: 1862153

Strand: Direct

Name: sstT

Synonym: ACIAD1866

Alternate gene names: 50085010

Gene position: 1860954-1862153 (Clockwise)

Preceding gene: 50085009

Following gene: 50085011

Centisome position: 51.71

GC content: 37.83

Gene sequence:

>1200_bases
ATGTTTTCAATATTATTGCGCTTAAGCCTAGTAACCAAGATTTTTATTGCGATTATTTTGGGCTTTGTTGTAGCTTTTCT
TTTTCCAAATATGACGCCATACTTTAGTATTTTTGGTGAAATTTTCATCAAAGCGTTAAAGGCTGTAGCCCCCATTTTGG
TATTTGTACTCGTTATCTCATCGATTGCCAATTTTAATGTTGAGCAAAGTGCCAAGAATTTTAAGCCTATTCTTTTTCTT
TATATTGTCAGTATGCTTTTTGCAGCATTTAGTGCAGTAATTGCAGATTTATTATTCCCCACTACACTTGTACTTGCTTC
ATCTGCAGATCAGGCATTTCAACCGCCTGGTAGTTTAAATGATGTCCTTAAAAATCTGATACTAAGCTTTGTGTCCAATC
CTGTTGTTGCCCTTAGTGAGGCTAACTTTATTGGTATTCTTGCTTGGGCAATCATTTTGGGTACAGCTTTTAGACATAGC
ACTCAGGCTACAAAAACTGTATTACAAGATTGTGCTGATGCTATCGGAAAAGTGATTCATTTGGTGATCAGTTTTGCCCC
TATTGGTATTTTTGGATTAGTGGCCGTAACATTTGCTCATTCTGGGATCGAAACTTTAAAAAGTTATTCTCATTTGTTAC
TTGTTTTGTTAGGTACAATGTTCTTTATGGCGCTTATAGTCAATCCGATTATGGTGGCGTGTGTCATTAAGAAAAATCCT
TATCCACTGGTCTTTAAATGTTTAAGAGAAAGTGGGATCACTGCATTCTTTACACGTAGTTCTGCTGCCAATATACCTGT
CAATCTGGACTTAGCTCGCAGATGTGGCGTAGATGAATCTACAAGTAATGTAATTATCCCGTTAGGTTCTACCGTTAATA
TGTGTGGTGCAGCCATTACAATCACTGTATTAACATTGGCGACAGTCAATACCTTAGGAATTTCAGTTGATATCTGGACT
ATGTTGATTCTATGCGTAGTTGCAAGTATTTCTGCATGTGGTGCTTCTGGTGTTGCTGGGGGATCATTACTCTTAGTGCC
TGTAGCATGTAGCTTATTTGGAATTTCTTCTGATATTGCCATGCAGGTGGTGGCGATTGGGATGGTCATTAGTGTTTTAC
AGGATTCGACTGAGACAGCACTTAACTCTTCTACAGATGTATTATTTGTGATTGCGGTTGATCAGGCATCTAAGACGTAA

Upstream 100 bases:

>100_bases
AACAAGCAACTTTGCAAAAAAAAATTATGCTTTTCTGAAGTTATGTATAAAATAGCGACCTTATTTTCTTTTGGCCGATT
AAGCTTGTAGGCTACACTTT

Downstream 100 bases:

>100_bases
TACATTTAGCTCAGTTATTTTCAATCTACGGTTTTAAAATGCCACTGCAAAGCTTACCAAATTGGGTTCAGTTTGCTGTA
TTTTTACTTGCGATGAACGC

Product: serine/threonine transporter SstT

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MFSILLRLSLVTKIFIAIILGFVVAFLFPNMTPYFSIFGEIFIKALKAVAPILVFVLVISSIANFNVEQSAKNFKPILFL
YIVSMLFAAFSAVIADLLFPTTLVLASSADQAFQPPGSLNDVLKNLILSFVSNPVVALSEANFIGILAWAIILGTAFRHS
TQATKTVLQDCADAIGKVIHLVISFAPIGIFGLVAVTFAHSGIETLKSYSHLLLVLLGTMFFMALIVNPIMVACVIKKNP
YPLVFKCLRESGITAFFTRSSAANIPVNLDLARRCGVDESTSNVIIPLGSTVNMCGAAITITVLTLATVNTLGISVDIWT
MLILCVVASISACGASGVAGGSLLLVPVACSLFGISSDIAMQVVAIGMVISVLQDSTETALNSSTDVLFVIAVDQASKT

Sequences:

>Translated_399_residues
MFSILLRLSLVTKIFIAIILGFVVAFLFPNMTPYFSIFGEIFIKALKAVAPILVFVLVISSIANFNVEQSAKNFKPILFL
YIVSMLFAAFSAVIADLLFPTTLVLASSADQAFQPPGSLNDVLKNLILSFVSNPVVALSEANFIGILAWAIILGTAFRHS
TQATKTVLQDCADAIGKVIHLVISFAPIGIFGLVAVTFAHSGIETLKSYSHLLLVLLGTMFFMALIVNPIMVACVIKKNP
YPLVFKCLRESGITAFFTRSSAANIPVNLDLARRCGVDESTSNVIIPLGSTVNMCGAAITITVLTLATVNTLGISVDIWT
MLILCVVASISACGASGVAGGSLLLVPVACSLFGISSDIAMQVVAIGMVISVLQDSTETALNSSTDVLFVIAVDQASKT
>Mature_399_residues
MFSILLRLSLVTKIFIAIILGFVVAFLFPNMTPYFSIFGEIFIKALKAVAPILVFVLVISSIANFNVEQSAKNFKPILFL
YIVSMLFAAFSAVIADLLFPTTLVLASSADQAFQPPGSLNDVLKNLILSFVSNPVVALSEANFIGILAWAIILGTAFRHS
TQATKTVLQDCADAIGKVIHLVISFAPIGIFGLVAVTFAHSGIETLKSYSHLLLVLLGTMFFMALIVNPIMVACVIKKNP
YPLVFKCLRESGITAFFTRSSAANIPVNLDLARRCGVDESTSNVIIPLGSTVNMCGAAITITVLTLATVNTLGISVDIWT
MLILCVVASISACGASGVAGGSLLLVPVACSLFGISSDIAMQVVAIGMVISVLQDSTETALNSSTDVLFVIAVDQASKT

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)

COG id: COG3633

COG function: function code E; Na+/serine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family

Homologues:

Organism=Homo sapiens, GI169790839, Length=310, Percent_Identity=22.5806451612903, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI223468566, Length=273, Percent_Identity=26.7399267399267, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI223468564, Length=254, Percent_Identity=26.7716535433071, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4827012, Length=245, Percent_Identity=23.6734693877551, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI5032093, Length=305, Percent_Identity=27.5409836065574, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI21314632, Length=262, Percent_Identity=27.0992366412214, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789473, Length=398, Percent_Identity=55.5276381909548, Blast_Score=406, Evalue=1e-114,
Organism=Escherichia coli, GI1789947, Length=360, Percent_Identity=23.3333333333333, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790514, Length=420, Percent_Identity=24.2857142857143, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71983106, Length=440, Percent_Identity=22.2727272727273, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71983099, Length=439, Percent_Identity=22.0956719817768, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193206505, Length=427, Percent_Identity=22.7166276346604, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24583025, Length=436, Percent_Identity=22.4770642201835, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI17137668, Length=436, Percent_Identity=22.4770642201835, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24583023, Length=436, Percent_Identity=22.4770642201835, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSTT_ACIAD (Q6FB65)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046520.1
- ProteinModelPortal:   Q6FB65
- SMR:   Q6FB65
- STRING:   Q6FB65
- GeneID:   2879227
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1866
- NMPDR:   fig|62977.3.peg.1782
- eggNOG:   COG3633
- HOGENOM:   HBG289387
- OMA:   FSHEAAK
- PhylomeDB:   Q6FB65
- ProtClustDB:   PRK13628
- BioCyc:   ASP62977:ACIAD1866-MONOMER
- HAMAP:   MF_01582
- InterPro:   IPR001991
- InterPro:   IPR023025
- PANTHER:   PTHR11958
- PRINTS:   PR00173

Pfam domain/function: PF00375 SDF

EC number: NA

Molecular weight: Translated: 42241; Mature: 42241

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: PS00713 NA_DICARBOXYL_SYMP_1; PS00714 NA_DICARBOXYL_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x183ee6a0)-; HASH(0x185201f4)-; HASH(0x1883d668)-; HASH(0x187c551c)-; HASH(0x1793c130)-; HASH(0x18903640)-; HASH(0x181a2fe4)-; HASH(0x18da50a0)-; HASH(0x17879738)-;

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA