Click here to switch to the map view.

The map label for this gene is quiA [H]

Identifier: 50084870

GI number: 50084870

Start: 1721187

End: 1723583

Strand: Direct

Name: quiA [H]

Synonym: ACIAD1716

Alternate gene names: 50084870

Gene position: 1721187-1723583 (Clockwise)

Preceding gene: 50084869

Following gene: 50084873

Centisome position: 47.83

GC content: 42.93

Gene sequence:

>2397_bases
TTGAAAGTATGGTGTTTTATACTTGGGCTGGCGTTACTTATTACTGGTGCATTTTATGTTATCGGTGGTGGAAAACTGAT
TAGCTTGGGTGGTTCATGGTACTTCCTGATTGCTGGTTTAATGATTACTACCTCAGCTTTTTTTATGTTCAAGAAAAAAG
CAACCGGGGTCTGGTTATATGCTTTGGCCTTCATTGGTACTGTTATTTGGGCGTTAATTGATGCTGGTTTCGAATTTTGG
CCATTGCATTCACGTTTGATGTTCCCAGCAGGTTTATTTGCTGCGGTCATGTTAACCTTGCCATCTATTCGTAAATACCA
ATATCAAACCCCAATGAGCGCTCCAGCATATGTCATTGGTGGTTTGACCGTTTTAGGAATGCTCGGTGGTCTGTATGGAA
TGTTTATTCCACATGAAACTGTGAAAGCATCTGGCGAAGAACTACCACTTGTTCCAGTTGACCCTGCCAAAAAACAGGTA
AATTGGGATCATTATGGTAATGATGCTGGCGGCAGTCGTTTTGTAGCGCTTGATCAGATTAACCGTAACAACGTATCTAA
ATTAAAAGAAGCTTGGCGTTTCCGTACAGGTGATTTTACGACTGGTACAGGTAACGGTGCAGAAGATCAAATGACACCAT
TGCAAGTTGGCAATAAAGTATTCTTGTGTACACCACATAATAATATATTTGCAATTGATGCAGACTCTGGAAAGCAGCTT
TGGAAAGCAGAAGTTAACTCTACTGCGGATGCATGGGAACGTTGTCGTGGCGTCGCTTATTTTGATTCGACACAACCATT
GGTACAACCTACATTGGCTGGTGCAACACCTGTAGCTGCTTTAGCAGCAAATACTGAGTGTCCGCGACGTGTATATACCA
ATACTGTAGATGGCCGTTTGATTGCAGTAAATGCAGATACAGGCGCTCGTTGTAAAGACTTTGGTGTTAATGGTACAGTG
AATTTACATGAAGGACTTGGTGAAAATACTAAGGCACCTCGCTTTGAAGTCACTTCGGCACCTACCATTGCAGGTACAAC
GATTGTCGTGGGAAGCCGTATTGCAGATAACGTGGCAGCCGATATGCCTGGTGGAGTCATTCGTGCCTATGATGTGATTA
CAGGTAAATTACGTTGGGCATTTGATCCACGTAATCCAGATCCAAACTACGTTTTAAAACCAGGTGAGATTTACAAACGC
AGTTCTACGAACTCATGGGCAGCCATGTCTTATGACCCGCAAATGAATACCGTGTTCTTGCCAATGGGAAGTTCATCTGT
AGACGTTTGGGGTGGTAATCGTACTGCAGCCGACCATAAATATAATACCTCTGTACTTGCACTTGATGCGACGACAGGTA
AAGAAAAATGGGTTTATAATACTGTTCATAATGACCTTTGGGATTTTGACTTACCAATGCAACCAAGTTTGGTAGACTTC
CCAATGAAAGATGGTACAACTAAACCTGCGGTTGTTATTGGCACTAAATCAGGTCAGTTTTATGTACTTGATCGTGTGAC
AGGTAAACCACTGACTAAAGTGATCGAGCAGCCAATTAAAGTGGCTGATATTCCTGGCGAACAATACAGTAAAACTCAGC
CGCGTTCAGTTGAAATGCCGCAAATTGGTAATCAGACACTTAAAGAGTCTGATATGTGGGGCGCGACGCCATTTGATCAG
TTGATGTGTCGTATCAACTTTAAATCAATGCGTTATGACGGGCTTTACACCGCACCAGGTACTGATGTATCACTGAGCTT
CCCGGGTTCTCTGGGTGGTATGAACTGGGGTTCTATCGCATTTGATCCAACGCACCGTTATATGTTTGTGAATGACATGC
GTTTAGGGCTTTGGATTCAATTGATCAAGCAGACTCCTGAAGATATCAAAATTCAGGCAAATGGTGGCGAGAAAGTTAAT
ACAGGTATGGGTGCAGTTCCAATGAAAGGTACGCCATATAAAGTGAATAAAAACCGCTTTATGTCAGCGTTGGGCATTCC
ATGTCAAAAACCACCTTTTGGTACCATGACTGCAATTGATATGAAAACACGTCAAGTGGCTTGGCAAGTACCATTGGGTA
CGATTCAAGACACGGGTCCAATGGGTATTAAAATGGGCTTGAAAGCACCAATTGGTATGCCAACCATTGGTGGTCCTATG
GCGACTCAAGGCGGGTTAGTATTCTTTGCTGCAACGCAAGACTACTACTTACGTGCGTTTAACTCATCTAATGGTAAAGA
GTTGTGGAAAGCACGTCTTCCTGTGGGTAGTCAAGGTACGCCTATGAGTTATATGTCACCAAAAACTGGAAAACAATACG
TTGTTGTTTCAGCAGGTGGTGCACGTCAGTCTCCAGATCATGGTGACTACGTGATTGCATATGCCCTTGAAAAATAA

Upstream 100 bases:

>100_bases
TGTGTTTTATACGTGATGATGAGAATGACTCTCTGTACTCATGATCACGATACGTGGAGAAAGATGTATGTCTGACCCTC
AAGAAAAGTCTCACATCATA

Downstream 100 bases:

>100_bases
TTCAATCGCTTAAAAAAAAGGGACTCTCAGGAGTCCCTTTTATTCTTACTATATATTTTCTAAATAATTTTTCTACTTAT
TTATCAACTGATCTAAAATA

Product: quinate/shikimate dehydrogenase [pyrroloquinoline-quinone] (NAD(P)-independent quinate dehydrogenase)

Products: NA

Alternate protein names: NAD(P)-independent quinate dehydrogenase [H]

Number of amino acids: Translated: 798; Mature: 798

Protein sequence:

>798_residues
MKVWCFILGLALLITGAFYVIGGGKLISLGGSWYFLIAGLMITTSAFFMFKKKATGVWLYALAFIGTVIWALIDAGFEFW
PLHSRLMFPAGLFAAVMLTLPSIRKYQYQTPMSAPAYVIGGLTVLGMLGGLYGMFIPHETVKASGEELPLVPVDPAKKQV
NWDHYGNDAGGSRFVALDQINRNNVSKLKEAWRFRTGDFTTGTGNGAEDQMTPLQVGNKVFLCTPHNNIFAIDADSGKQL
WKAEVNSTADAWERCRGVAYFDSTQPLVQPTLAGATPVAALAANTECPRRVYTNTVDGRLIAVNADTGARCKDFGVNGTV
NLHEGLGENTKAPRFEVTSAPTIAGTTIVVGSRIADNVAADMPGGVIRAYDVITGKLRWAFDPRNPDPNYVLKPGEIYKR
SSTNSWAAMSYDPQMNTVFLPMGSSSVDVWGGNRTAADHKYNTSVLALDATTGKEKWVYNTVHNDLWDFDLPMQPSLVDF
PMKDGTTKPAVVIGTKSGQFYVLDRVTGKPLTKVIEQPIKVADIPGEQYSKTQPRSVEMPQIGNQTLKESDMWGATPFDQ
LMCRINFKSMRYDGLYTAPGTDVSLSFPGSLGGMNWGSIAFDPTHRYMFVNDMRLGLWIQLIKQTPEDIKIQANGGEKVN
TGMGAVPMKGTPYKVNKNRFMSALGIPCQKPPFGTMTAIDMKTRQVAWQVPLGTIQDTGPMGIKMGLKAPIGMPTIGGPM
ATQGGLVFFAATQDYYLRAFNSSNGKELWKARLPVGSQGTPMSYMSPKTGKQYVVVSAGGARQSPDHGDYVIAYALEK

Sequences:

>Translated_798_residues
MKVWCFILGLALLITGAFYVIGGGKLISLGGSWYFLIAGLMITTSAFFMFKKKATGVWLYALAFIGTVIWALIDAGFEFW
PLHSRLMFPAGLFAAVMLTLPSIRKYQYQTPMSAPAYVIGGLTVLGMLGGLYGMFIPHETVKASGEELPLVPVDPAKKQV
NWDHYGNDAGGSRFVALDQINRNNVSKLKEAWRFRTGDFTTGTGNGAEDQMTPLQVGNKVFLCTPHNNIFAIDADSGKQL
WKAEVNSTADAWERCRGVAYFDSTQPLVQPTLAGATPVAALAANTECPRRVYTNTVDGRLIAVNADTGARCKDFGVNGTV
NLHEGLGENTKAPRFEVTSAPTIAGTTIVVGSRIADNVAADMPGGVIRAYDVITGKLRWAFDPRNPDPNYVLKPGEIYKR
SSTNSWAAMSYDPQMNTVFLPMGSSSVDVWGGNRTAADHKYNTSVLALDATTGKEKWVYNTVHNDLWDFDLPMQPSLVDF
PMKDGTTKPAVVIGTKSGQFYVLDRVTGKPLTKVIEQPIKVADIPGEQYSKTQPRSVEMPQIGNQTLKESDMWGATPFDQ
LMCRINFKSMRYDGLYTAPGTDVSLSFPGSLGGMNWGSIAFDPTHRYMFVNDMRLGLWIQLIKQTPEDIKIQANGGEKVN
TGMGAVPMKGTPYKVNKNRFMSALGIPCQKPPFGTMTAIDMKTRQVAWQVPLGTIQDTGPMGIKMGLKAPIGMPTIGGPM
ATQGGLVFFAATQDYYLRAFNSSNGKELWKARLPVGSQGTPMSYMSPKTGKQYVVVSAGGARQSPDHGDYVIAYALEK
>Mature_798_residues
MKVWCFILGLALLITGAFYVIGGGKLISLGGSWYFLIAGLMITTSAFFMFKKKATGVWLYALAFIGTVIWALIDAGFEFW
PLHSRLMFPAGLFAAVMLTLPSIRKYQYQTPMSAPAYVIGGLTVLGMLGGLYGMFIPHETVKASGEELPLVPVDPAKKQV
NWDHYGNDAGGSRFVALDQINRNNVSKLKEAWRFRTGDFTTGTGNGAEDQMTPLQVGNKVFLCTPHNNIFAIDADSGKQL
WKAEVNSTADAWERCRGVAYFDSTQPLVQPTLAGATPVAALAANTECPRRVYTNTVDGRLIAVNADTGARCKDFGVNGTV
NLHEGLGENTKAPRFEVTSAPTIAGTTIVVGSRIADNVAADMPGGVIRAYDVITGKLRWAFDPRNPDPNYVLKPGEIYKR
SSTNSWAAMSYDPQMNTVFLPMGSSSVDVWGGNRTAADHKYNTSVLALDATTGKEKWVYNTVHNDLWDFDLPMQPSLVDF
PMKDGTTKPAVVIGTKSGQFYVLDRVTGKPLTKVIEQPIKVADIPGEQYSKTQPRSVEMPQIGNQTLKESDMWGATPFDQ
LMCRINFKSMRYDGLYTAPGTDVSLSFPGSLGGMNWGSIAFDPTHRYMFVNDMRLGLWIQLIKQTPEDIKIQANGGEKVN
TGMGAVPMKGTPYKVNKNRFMSALGIPCQKPPFGTMTAIDMKTRQVAWQVPLGTIQDTGPMGIKMGLKAPIGMPTIGGPM
ATQGGLVFFAATQDYYLRAFNSSNGKELWKARLPVGSQGTPMSYMSPKTGKQYVVVSAGGARQSPDHGDYVIAYALEK

Specific function: Can act either on quinate or on shikimate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=796, Percent_Identity=39.572864321608, Blast_Score=552, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.99.25 [H]

Molecular weight: Translated: 86949; Mature: 86949

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS00363 BACTERIAL_PQQ_1 ; PS00364 BACTERIAL_PQQ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVWCFILGLALLITGAFYVIGGGKLISLGGSWYFLIAGLMITTSAFFMFKKKATGVWLY
CCHHHHHHHHHHHHHCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHEEEECCCCCHHHH
ALAFIGTVIWALIDAGFEFWPLHSRLMFPAGLFAAVMLTLPSIRKYQYQTPMSAPAYVIG
HHHHHHHHHHHHHHCCCEEEECCHHHHCCHHHHHHHHHHCCCHHHEEECCCCCCCHHHHH
GLTVLGMLGGLYGMFIPHETVKASGEELPLVPVDPAKKQVNWDHYGNDAGGSRFVALDQI
HHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEECCCCHHCCCCCCCCCCCCCCEEEEEECC
NRNNVSKLKEAWRFRTGDFTTGTGNGAEDQMTPLQVGNKVFLCTPHNNIFAIDADSGKQL
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEECCCCCEEEEECCCCCHH
WKAEVNSTADAWERCRGVAYFDSTQPLVQPTLAGATPVAALAANTECPRRVYTNTVDGRL
HHHHCCCCHHHHHHHCCEEEECCCCCHHCHHHCCCCCHHHEECCCCCCHHHHCCCCCCEE
IAVNADTGARCKDFGVNGTVNLHEGLGENTKAPRFEVTSAPTIAGTTIVVGSRIADNVAA
EEEECCCCCCCEECCCCCEEEHHCCCCCCCCCCEEEECCCCCCCCEEEEECCHHHHHHHH
DMPGGVIRAYDVITGKLRWAFDPRNPDPNYVLKPGEIYKRSSTNSWAAMSYDPQMNTVFL
CCCCCEEEEEEEEEEEEEEEECCCCCCCCEEECCCHHEECCCCCCEEEEEECCCCCEEEE
PMGSSSVDVWGGNRTAADHKYNTSVLALDATTGKEKWVYNTVHNDLWDFDLPMQPSLVDF
ECCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEHHHCCCCCCCCCCCCCEEEC
PMKDGTTKPAVVIGTKSGQFYVLDRVTGKPLTKVIEQPIKVADIPGEQYSKTQPRSVEMP
CCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHCCCEEEECCCHHCCCCCCCCCCCC
QIGNQTLKESDMWGATPFDQLMCRINFKSMRYDGLYTAPGTDVSLSFPGSLGGMNWGSIA
CCCCCHHHHCCCCCCCCHHHHEEEEEHHHEEECCEEECCCCCEEEECCCCCCCCCCCCEE
FDPTHRYMFVNDMRLGLWIQLIKQTPEDIKIQANGGEKVNTGMGAVPMKGTPYKVNKNRF
ECCCCEEEEEECCHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCCCCCCCEEECHHHH
MSALGIPCQKPPFGTMTAIDMKTRQVAWQVPLGTIQDTGPMGIKMGLKAPIGMPTIGGPM
HHHHCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
ATQGGLVFFAATQDYYLRAFNSSNGKELWKARLPVGSQGTPMSYMSPKTGKQYVVVSAGG
CCCCCEEEEEECCCEEEEEECCCCCHHHHHEECCCCCCCCCCCCCCCCCCCEEEEEECCC
ARQSPDHGDYVIAYALEK
CCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MKVWCFILGLALLITGAFYVIGGGKLISLGGSWYFLIAGLMITTSAFFMFKKKATGVWLY
CCHHHHHHHHHHHHHCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHEEEECCCCCHHHH
ALAFIGTVIWALIDAGFEFWPLHSRLMFPAGLFAAVMLTLPSIRKYQYQTPMSAPAYVIG
HHHHHHHHHHHHHHCCCEEEECCHHHHCCHHHHHHHHHHCCCHHHEEECCCCCCCHHHHH
GLTVLGMLGGLYGMFIPHETVKASGEELPLVPVDPAKKQVNWDHYGNDAGGSRFVALDQI
HHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEECCCCHHCCCCCCCCCCCCCCEEEEEECC
NRNNVSKLKEAWRFRTGDFTTGTGNGAEDQMTPLQVGNKVFLCTPHNNIFAIDADSGKQL
CCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEECCCCCEEEEECCCCCHH
WKAEVNSTADAWERCRGVAYFDSTQPLVQPTLAGATPVAALAANTECPRRVYTNTVDGRL
HHHHCCCCHHHHHHHCCEEEECCCCCHHCHHHCCCCCHHHEECCCCCCHHHHCCCCCCEE
IAVNADTGARCKDFGVNGTVNLHEGLGENTKAPRFEVTSAPTIAGTTIVVGSRIADNVAA
EEEECCCCCCCEECCCCCEEEHHCCCCCCCCCCEEEECCCCCCCCEEEEECCHHHHHHHH
DMPGGVIRAYDVITGKLRWAFDPRNPDPNYVLKPGEIYKRSSTNSWAAMSYDPQMNTVFL
CCCCCEEEEEEEEEEEEEEEECCCCCCCCEEECCCHHEECCCCCCEEEEEECCCCCEEEE
PMGSSSVDVWGGNRTAADHKYNTSVLALDATTGKEKWVYNTVHNDLWDFDLPMQPSLVDF
ECCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCEEEEHHHCCCCCCCCCCCCCEEEC
PMKDGTTKPAVVIGTKSGQFYVLDRVTGKPLTKVIEQPIKVADIPGEQYSKTQPRSVEMP
CCCCCCCCCEEEEEECCCCEEEEECCCCCHHHHHHHCCCEEEECCCHHCCCCCCCCCCCC
QIGNQTLKESDMWGATPFDQLMCRINFKSMRYDGLYTAPGTDVSLSFPGSLGGMNWGSIA
CCCCCHHHHCCCCCCCCHHHHEEEEEHHHEEECCEEECCCCCEEEECCCCCCCCCCCCEE
FDPTHRYMFVNDMRLGLWIQLIKQTPEDIKIQANGGEKVNTGMGAVPMKGTPYKVNKNRF
ECCCCEEEEEECCHHHHHHHHHHCCCCCEEEEECCCCEECCCCCCCCCCCCCEEECHHHH
MSALGIPCQKPPFGTMTAIDMKTRQVAWQVPLGTIQDTGPMGIKMGLKAPIGMPTIGGPM
HHHHCCCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCCCCCC
ATQGGLVFFAATQDYYLRAFNSSNGKELWKARLPVGSQGTPMSYMSPKTGKQYVVVSAGG
CCCCCEEEEEECCCEEEEEECCCCCHHHHHEECCCCCCCCCCCCCCCCCCCEEEEEECCC
ARQSPDHGDYVIAYALEK
CCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002591; 7592351 [H]