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The map label for this gene is caiB [H]

Identifier: 50084842

GI number: 50084842

Start: 1691122

End: 1692345

Strand: Direct

Name: caiB [H]

Synonym: ACIAD1687

Alternate gene names: 50084842

Gene position: 1691122-1692345 (Clockwise)

Preceding gene: 50084840

Following gene: 50084848

Centisome position: 46.99

GC content: 41.18

Gene sequence:

>1224_bases
ATGGGTGCCTTAACAGGATTTAGGGTTCTGGATTTAAGCAGGATTTTAGCTGGACCTTGGTGTAGTCAGGTATTGGCAGA
CTTGGGCGCAGAAGTAATTAAGATAGAAAAGCCATTTTATGGTGATGATACACGCATTTGGGGGCCTCCATTTCTTAAAA
ATGATGATGGTAAGGAGACGACTGAATCTGCTTATTATTTATCAGCAAATCGTGGTAAACATTCGGTTGCAATTGATATG
GCAACAGAAGAAGGTCAGGCACTAATCAGAAAAATGGTGTTAGAAAGTGATGTTGTGATCGAAAACTATAAAGCGGGCTC
ACTCAAGAAATATGGTCTGGACTATGAAAGTTTAAGTCAGATCAACCCCAAACTGGTGTATTGCTCGATTACTGGTTTTG
GACAGAAAGGCCCACGTGCGGCTGAACTTGGCTATGATTTTATTATTCAGGGGATGGGCGGTATGATGAGTGTAACAGGT
GAGCGAGATGATTTACCTGGCGGAGGGCCTCAAAAAGCAGGTTTGGCTTTTGCAGATTTGACGACAGGTTTATATGCAGC
CATTGCCATTCAGGCTGCATTGTTGTCACGAGTAACCACTGGCGAAGGCCAGCATATAGATATGGCCTTGTTGGATACAC
AGGTTGCATCACTCTCAGTTCTGGCTATGAATTATTTAACATCGACCAAAGTACCAGGTCGGTTTGGAAATGCGCATGCC
AATATCGTGCCTTATCAAGTCTTCAAGGCAAAAGAAGGGGAATTTATTATTGCTTGTGGTAACGATCAGCAGTTTCAGGC
CTTATGTGAAAGTATAGGATTGCCTGAACTGTGCAAAAACTCCAAATTTACTAAAAATAAAGATCGGGTCACGCATCGAG
AAGAGATCAGTCATATCTTACAACAACACTTTATGACAGAGATTGCCCAGCTATGGGTTGATCGTATTCATAAAGTTAAG
GTGCCTGTGGGTATGATTAATAATTTACAGCAGACCTTGGAGGAAGAGCAGGTGGTTTTCCGTGAGATGGTAATTCATAT
GCAGCATCCGTTGCGTTCTGATTATATTTCGATTGGATCGCCGATCAAACTATCCAAAACACCTGTCGAGTATCTAAAAG
CACCCCCTTATTTGGGTGAAGATACTGATCAGATTTTAAATCGATTTTTATCTGATAAAGAATTACATGATTTAAAAGAT
AGAAAAGTGATTCAACAAGGTTGA

Upstream 100 bases:

>100_bases
TTTACAATAATAAAATTTTATTTTGCAATGCGATATTTTAGTCTATTATTAATTAAATTTATTTTAATTAAGACCACAAC
TAAACGCAAAAGAGGGAAAT

Downstream 100 bases:

>100_bases
TTCTCTTGGAGCAGGCGGGCTGCTCCTTTTTAATTTAAAGACTTTCTGTCAAAGCATCCTGAATACTGTTTACCATATAT
TTTAATCGCGGCCCAATATC

Product: L-carnitine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MGALTGFRVLDLSRILAGPWCSQVLADLGAEVIKIEKPFYGDDTRIWGPPFLKNDDGKETTESAYYLSANRGKHSVAIDM
ATEEGQALIRKMVLESDVVIENYKAGSLKKYGLDYESLSQINPKLVYCSITGFGQKGPRAAELGYDFIIQGMGGMMSVTG
ERDDLPGGGPQKAGLAFADLTTGLYAAIAIQAALLSRVTTGEGQHIDMALLDTQVASLSVLAMNYLTSTKVPGRFGNAHA
NIVPYQVFKAKEGEFIIACGNDQQFQALCESIGLPELCKNSKFTKNKDRVTHREEISHILQQHFMTEIAQLWVDRIHKVK
VPVGMINNLQQTLEEEQVVFREMVIHMQHPLRSDYISIGSPIKLSKTPVEYLKAPPYLGEDTDQILNRFLSDKELHDLKD
RKVIQQG

Sequences:

>Translated_407_residues
MGALTGFRVLDLSRILAGPWCSQVLADLGAEVIKIEKPFYGDDTRIWGPPFLKNDDGKETTESAYYLSANRGKHSVAIDM
ATEEGQALIRKMVLESDVVIENYKAGSLKKYGLDYESLSQINPKLVYCSITGFGQKGPRAAELGYDFIIQGMGGMMSVTG
ERDDLPGGGPQKAGLAFADLTTGLYAAIAIQAALLSRVTTGEGQHIDMALLDTQVASLSVLAMNYLTSTKVPGRFGNAHA
NIVPYQVFKAKEGEFIIACGNDQQFQALCESIGLPELCKNSKFTKNKDRVTHREEISHILQQHFMTEIAQLWVDRIHKVK
VPVGMINNLQQTLEEEQVVFREMVIHMQHPLRSDYISIGSPIKLSKTPVEYLKAPPYLGEDTDQILNRFLSDKELHDLKD
RKVIQQG
>Mature_406_residues
GALTGFRVLDLSRILAGPWCSQVLADLGAEVIKIEKPFYGDDTRIWGPPFLKNDDGKETTESAYYLSANRGKHSVAIDMA
TEEGQALIRKMVLESDVVIENYKAGSLKKYGLDYESLSQINPKLVYCSITGFGQKGPRAAELGYDFIIQGMGGMMSVTGE
RDDLPGGGPQKAGLAFADLTTGLYAAIAIQAALLSRVTTGEGQHIDMALLDTQVASLSVLAMNYLTSTKVPGRFGNAHAN
IVPYQVFKAKEGEFIIACGNDQQFQALCESIGLPELCKNSKFTKNKDRVTHREEISHILQQHFMTEIAQLWVDRIHKVKV
PVGMINNLQQTLEEEQVVFREMVIHMQHPLRSDYISIGSPIKLSKTPVEYLKAPPYLGEDTDQILNRFLSDKELHDLKDR
KVIQQG

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=405, Percent_Identity=42.2222222222222, Blast_Score=335, Evalue=4e-92,
Organism=Homo sapiens, GI300863124, Length=431, Percent_Identity=39.6751740139211, Blast_Score=321, Evalue=7e-88,
Organism=Homo sapiens, GI13376042, Length=431, Percent_Identity=36.6589327146172, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI300863126, Length=405, Percent_Identity=36.5432098765432, Blast_Score=275, Evalue=4e-74,
Organism=Homo sapiens, GI266456254, Length=415, Percent_Identity=26.2650602409639, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI42794625, Length=415, Percent_Identity=26.2650602409639, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI266458393, Length=268, Percent_Identity=30.2238805970149, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI266458397, Length=267, Percent_Identity=29.9625468164794, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI266458395, Length=145, Percent_Identity=33.1034482758621, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI42822893, Length=153, Percent_Identity=32.0261437908497, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI87082093, Length=364, Percent_Identity=35.4395604395604, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1788717, Length=425, Percent_Identity=28, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1786222, Length=418, Percent_Identity=24.6411483253589, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI115535051, Length=311, Percent_Identity=26.0450160771704, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI32564160, Length=317, Percent_Identity=24.6056782334385, Blast_Score=88, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24648431, Length=404, Percent_Identity=44.3069306930693, Blast_Score=344, Evalue=8e-95,
Organism=Drosophila melanogaster, GI24585488, Length=318, Percent_Identity=26.1006289308176, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 45097; Mature: 44966

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALTGFRVLDLSRILAGPWCSQVLADLGAEVIKIEKPFYGDDTRIWGPPFLKNDDGKET
CCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
TESAYYLSANRGKHSVAIDMATEEGQALIRKMVLESDVVIENYKAGSLKKYGLDYESLSQ
CCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCHHHHHC
INPKLVYCSITGFGQKGPRAAELGYDFIIQGMGGMMSVTGERDDLPGGGPQKAGLAFADL
CCCEEEEEEEECCCCCCCCHHHCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEHHHH
TTGLYAAIAIQAALLSRVTTGEGQHIDMALLDTQVASLSVLAMNYLTSTKVPGRFGNAHA
HHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NIVPYQVFKAKEGEFIIACGNDQQFQALCESIGLPELCKNSKFTKNKDRVTHREEISHIL
CCCCCEEEECCCCCEEEEECCCHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHH
QQHFMTEIAQLWVDRIHKVKVPVGMINNLQQTLEEEQVVFREMVIHMQHPLRSDYISIGS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
PIKLSKTPVEYLKAPPYLGEDTDQILNRFLSDKELHDLKDRKVIQQG
CCEECCCCHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GALTGFRVLDLSRILAGPWCSQVLADLGAEVIKIEKPFYGDDTRIWGPPFLKNDDGKET
CCCCCHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
TESAYYLSANRGKHSVAIDMATEEGQALIRKMVLESDVVIENYKAGSLKKYGLDYESLSQ
CCCEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCCCCHHHCCCHHHHHC
INPKLVYCSITGFGQKGPRAAELGYDFIIQGMGGMMSVTGERDDLPGGGPQKAGLAFADL
CCCEEEEEEEECCCCCCCCHHHCCHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEHHHH
TTGLYAAIAIQAALLSRVTTGEGQHIDMALLDTQVASLSVLAMNYLTSTKVPGRFGNAHA
HHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
NIVPYQVFKAKEGEFIIACGNDQQFQALCESIGLPELCKNSKFTKNKDRVTHREEISHIL
CCCCCEEEECCCCCEEEEECCCHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHH
QQHFMTEIAQLWVDRIHKVKVPVGMINNLQQTLEEEQVVFREMVIHMQHPLRSDYISIGS
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCC
PIKLSKTPVEYLKAPPYLGEDTDQILNRFLSDKELHDLKDRKVIQQG
CCEECCCCHHHHCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]