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The map label for this gene is putA [H]

Identifier: 50084804

GI number: 50084804

Start: 1642037

End: 1645825

Strand: Reverse

Name: putA [H]

Synonym: ACIAD1646

Alternate gene names: 50084804

Gene position: 1645825-1642037 (Counterclockwise)

Preceding gene: 50084806

Following gene: 50084803

Centisome position: 45.73

GC content: 42.25

Gene sequence:

>3789_bases
TTGTCATTGGAATTTGGCATGAATATGATGGATAACGACCCTCAAATGGACACAGCAAAACCTCATTTTGGATATATTTC
AGAATTTAAAGAAAAAACTGAACTGGAGCAGCATATCAACGATGCTTGGCGTCGTCCTGAACCAGAAACAGTTGAAACTT
TGCTACAAGCTGCCTCTATTTCCGATGAACTCAATCATAAAATTTATGAGCTGGCTTTTGAGCTAGCCAATGGACTACGT
GAGCGCAAAACCTCTTCTGGAAAAGCTGGAATCGTTCAAGGACTTTTACAGGAGTTTTCGCTTTCTTCTCAGGAAGGTAT
TGCTTTAATGTGCCTGGCAGAAGCTCTGCTACGTATTCCCGATGCAGCCACCCGAGATTTATTGATTCGAGATAAAATCA
ATCAAGGCAACTGGAAAGATCATGTGGGTCAGAGTAGCCTGATGTTTGTCAATGCTGCAGCTTGGGGGCTCATGCTGACA
GGCAAACTTATGGAAACGCCGAAACAAGGCAGTTTGTCTGGGTTATTAACTTCAATTTTGGCACGTAGTGGTCGAGGTGT
GATTCGTAAAGCAGTCGATGTTGCGATGCGAATGATGGGTGAACAATTTGTTACGGGTGAAACCATTGAAGAAGCGCTCG
ACAATGCAAAATCTCATGAACATAAAGGATTTCGTTATTCCTACGACATGCTGGGTGAAGCCGCTCTAACAACGCATGAT
GCCGAACGTTATTTTAATGATTATACGCAGGCCATCCATGCGATTGGTCAGGCATCGAATGGCAAAGGTGTGTATGATGG
GCCAGGAATTTCAATTAAACTTTCGGCACTGCATCCACGCTACCAACGTTCACAAATTGCACGAGTGCATGATGAACTCT
ATGGCAAAGTGTTTAATCTTGCCTTACTCTCCAAAAAATATGATATTGGTTTAAATATTGATGCTGAAGAAGCAGATCGC
CTTGAGATTTCTTTAGAATTACTTGAACGTCTATGCTTTGAGCCCGAACTTGCAGACTGGAAAGGGATCGGTTTTGTGAT
TCAAGCTTATCAAAAGCGTTGTTTCTACGTCGTTGATTATGTCGTTGATCTGGCAAAACGTAGCAAAAAACGCCTGATGA
TTCGTTTGGTGAAAGGTGCGTATTGGGATAGTGAAATCAAAAAAGCACAAATTGATGGTATGCACGATTATCCAGTCTTT
ACCCGTAAAGTGCATACTGATTTATCTTATATTGCTTGTGCCAAAAAACTGTTAGCAGCACCTGAGCAAATCTATCCGCA
GTTTGCCACGCATAATGCACAATCACTTGCTACAATTTATGAACTTGCTGATCCAGGCAAATATTATGCAGGCCAATACG
AATTTCAATGCTTACATGGCATGGGCGAACCCTTATACGAACAAGTAGTAGGTTCTCGCAGTGACAAAAAACTGGGGATT
CCATGCCGTATCTATGCACCTGTAGGCAATCATGAAACCTTACTTGCCTATCTGGTACGTCGATTGCTCGAAAATGGTGC
TAACACATCATTTGTGAATCGTATTGCTGATCAAAATCTAAAAATTGAAGATTTAATACAATCACCTTTTGATGAAATTG
CAATTAACGCACAACGTGAAGGTCAAGCTGGATTAAAACATCCTGCCATTCCTTTACCACACAATTTGTATGGATCATTA
CGTCAAAATTCGAAAGGTTTTGATCTTGCCAATGATGCAACTTTGACAGCGTTGAACGAAACTGCACAGCAGCTTGAACA
TAAAGTCTGGGAAAGTAGACCTTTACTAGCTCAAACTGTTGATCAAATTGATGTAAGCCCGCAAGCGTTGCTAAATCCAG
CGGTTCATTTAGATATTGTGGGCTACGTTCAGGAAGCGACGCTTGAGCAAGTTGATGTTGCGCTCGAATCTGCAACTCAG
GCTCAGCAGGCCTGGGCAAATACCGAGAAAAACCATCGGGCAGCTACACTCAAGAAAGCGGCAAACTTGATGGAATCACG
TATGCAGGAACTCATGGTCTTGCTGTGCCGTGAAGCAGGTAAAACTTATGCAAACGCAATTTCAGAAGTTCGTGAAGCAG
TAGATTTCTTACGTTATTATGCCACTCAAATCGAAAGTCTGAAGCCTACTGCTCAAATCGAGCCGTTAGGTACAGTCCTG
TGCATTAGCCCCTGGAACTTTCCATTGGCAATTTTTACAGGCCAGATTGCTGCGGCACTTGGTGCTGGAAACTGTGTCAT
TGCAAAACCTGCCGAACAGACACCATTAATTGCGGCACAGGCTGTACATATTTTACATGAAGCGGGTATTCCTAAAAGTG
TACTACAGCTTTTACCAGGCCGTGGTGAAACTGTCGGCGCCAAGCTCAGTAGTGACCAGCGTATTCAAGGTGTCATGTTT
ACTGGCTCAACAGAAGTTGCCAAGATTTTGCAAAAAACGGTAGCAAAACGACTTTCGCCTTCTGGTCATCCTATTCCTTT
AATTGCGGAAACTGGTGGTCAAAATGCCATGATTGTCGACTCATCTGCCTTGACAGAGCAAGTGGTGATTGATGTCTTGA
ATTCAGCTTTTGACAGTGCAGGTCAACGTTGTTCAGCTTTACGTATTTTATGCGTACAAGAAGACAATTCAAAAACACTA
GTGACTATGCTCAAAGGTGCAATGCAGCAACTGATTATGGGTAATCCATTTCTGCTCAAAACCGATATTGGTCCAGTGAT
TGATTTAGAGGCAAAACAAACCATTGATCAACATATTCAGAAAATGCGCAGCAAAGGTTATCCCGTATATCAGTTAATTT
TTAATCATGAAGCAGCATCGCAAGCGCAATTGAGCCAAGGAACATTTGTCACTCCAACCTTGATTGAATTACCCAATCTT
GATGATCTGGAACGTGAAGTATTTGGCCCTGTGTTACATGTCATTACTTATAAACATGGTGAAATAAAACAGCTACTTCA
ACATATTAATGCCAAAGGTTATGGTTTGACTATGGGATTGCATACTCGTATCGATGAAACCATCAATACAGTGGTACAAC
ATGCCGAAGTGGGTAATCTTTACATTAATCGTAATATCGTGGGTGCAGTGGTAGGTGTACAACCATTTGGGGGTGAAGGC
TTATCAGGTACAGGGCCTAAAGCAGGTGGTCCGCTTTACTTATATCGTTTAATGGCATCTTGCACAGAAAAAGCAATACA
GACTCCTTTTGGTATACCAGCAGAAAATGTTGCAGTGCCATTAACGCAACTCTCGTTATTCCGCGAGTTTTCGGCGTGGA
TTAAAAAGCAGTATCCTGCCCATCAACTTCCTAATGTCGTGCCATTGAATGTCGGTCATGCTTTTGACCTACAAGGCCCG
ACAGGTGAAACCAACCGCTATATGATGTTGCCACGTAAACGTATACTGGCAATAGCAAGTAATGAATTGGAACTATGTCA
TCAAATGCTGGCGATATTTGCAGTAAACAGTCAAGTTGCTTTATTAGAAAGTAATCCTTCTTTGCAAAAATTTGGACAGG
ATTTACCCACAGTAGTTCGTCAGGCGATTATTGAAATTCGTGGTGTTGAGCATGGCGATTTTGATGCAGTCTTACATCAT
GGTTCAACTGAGGAGTTGCAAGTTTTACAAACACAGATTGCAAATCGTCAAGGTCCGATTGTCGGCATTACTCATTTGCA
AAATTCAGAGCAAGTCATTCCACTCGAGCGTCTCGTCATTGAACATGCTATTAGTGTAAATACGGCAGCGGCTGGTGGTA
ATGCGAGTTTGATGACCATGTCGGAGTAA

Upstream 100 bases:

>100_bases
AAATTTTCCTCTAAAAAATGAATCAATTATAGTCAGTTATTTGGTAATTATTCTGTAATGATAAATTATCTAAACCCCTT
TAAACAATATACCTTAGAGT

Downstream 100 bases:

>100_bases
CTGTATTTAAATAATTGTGTCTGAATAAATCAAACCGATCTAATCATTTACCAAAAGCCCTGAATGTTTAATATTTGGGG
CTTTTGTTTTAGCCTGATGA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1262; Mature: 1261

Protein sequence:

>1262_residues
MSLEFGMNMMDNDPQMDTAKPHFGYISEFKEKTELEQHINDAWRRPEPETVETLLQAASISDELNHKIYELAFELANGLR
ERKTSSGKAGIVQGLLQEFSLSSQEGIALMCLAEALLRIPDAATRDLLIRDKINQGNWKDHVGQSSLMFVNAAAWGLMLT
GKLMETPKQGSLSGLLTSILARSGRGVIRKAVDVAMRMMGEQFVTGETIEEALDNAKSHEHKGFRYSYDMLGEAALTTHD
AERYFNDYTQAIHAIGQASNGKGVYDGPGISIKLSALHPRYQRSQIARVHDELYGKVFNLALLSKKYDIGLNIDAEEADR
LEISLELLERLCFEPELADWKGIGFVIQAYQKRCFYVVDYVVDLAKRSKKRLMIRLVKGAYWDSEIKKAQIDGMHDYPVF
TRKVHTDLSYIACAKKLLAAPEQIYPQFATHNAQSLATIYELADPGKYYAGQYEFQCLHGMGEPLYEQVVGSRSDKKLGI
PCRIYAPVGNHETLLAYLVRRLLENGANTSFVNRIADQNLKIEDLIQSPFDEIAINAQREGQAGLKHPAIPLPHNLYGSL
RQNSKGFDLANDATLTALNETAQQLEHKVWESRPLLAQTVDQIDVSPQALLNPAVHLDIVGYVQEATLEQVDVALESATQ
AQQAWANTEKNHRAATLKKAANLMESRMQELMVLLCREAGKTYANAISEVREAVDFLRYYATQIESLKPTAQIEPLGTVL
CISPWNFPLAIFTGQIAAALGAGNCVIAKPAEQTPLIAAQAVHILHEAGIPKSVLQLLPGRGETVGAKLSSDQRIQGVMF
TGSTEVAKILQKTVAKRLSPSGHPIPLIAETGGQNAMIVDSSALTEQVVIDVLNSAFDSAGQRCSALRILCVQEDNSKTL
VTMLKGAMQQLIMGNPFLLKTDIGPVIDLEAKQTIDQHIQKMRSKGYPVYQLIFNHEAASQAQLSQGTFVTPTLIELPNL
DDLEREVFGPVLHVITYKHGEIKQLLQHINAKGYGLTMGLHTRIDETINTVVQHAEVGNLYINRNIVGAVVGVQPFGGEG
LSGTGPKAGGPLYLYRLMASCTEKAIQTPFGIPAENVAVPLTQLSLFREFSAWIKKQYPAHQLPNVVPLNVGHAFDLQGP
TGETNRYMMLPRKRILAIASNELELCHQMLAIFAVNSQVALLESNPSLQKFGQDLPTVVRQAIIEIRGVEHGDFDAVLHH
GSTEELQVLQTQIANRQGPIVGITHLQNSEQVIPLERLVIEHAISVNTAAAGGNASLMTMSE

Sequences:

>Translated_1262_residues
MSLEFGMNMMDNDPQMDTAKPHFGYISEFKEKTELEQHINDAWRRPEPETVETLLQAASISDELNHKIYELAFELANGLR
ERKTSSGKAGIVQGLLQEFSLSSQEGIALMCLAEALLRIPDAATRDLLIRDKINQGNWKDHVGQSSLMFVNAAAWGLMLT
GKLMETPKQGSLSGLLTSILARSGRGVIRKAVDVAMRMMGEQFVTGETIEEALDNAKSHEHKGFRYSYDMLGEAALTTHD
AERYFNDYTQAIHAIGQASNGKGVYDGPGISIKLSALHPRYQRSQIARVHDELYGKVFNLALLSKKYDIGLNIDAEEADR
LEISLELLERLCFEPELADWKGIGFVIQAYQKRCFYVVDYVVDLAKRSKKRLMIRLVKGAYWDSEIKKAQIDGMHDYPVF
TRKVHTDLSYIACAKKLLAAPEQIYPQFATHNAQSLATIYELADPGKYYAGQYEFQCLHGMGEPLYEQVVGSRSDKKLGI
PCRIYAPVGNHETLLAYLVRRLLENGANTSFVNRIADQNLKIEDLIQSPFDEIAINAQREGQAGLKHPAIPLPHNLYGSL
RQNSKGFDLANDATLTALNETAQQLEHKVWESRPLLAQTVDQIDVSPQALLNPAVHLDIVGYVQEATLEQVDVALESATQ
AQQAWANTEKNHRAATLKKAANLMESRMQELMVLLCREAGKTYANAISEVREAVDFLRYYATQIESLKPTAQIEPLGTVL
CISPWNFPLAIFTGQIAAALGAGNCVIAKPAEQTPLIAAQAVHILHEAGIPKSVLQLLPGRGETVGAKLSSDQRIQGVMF
TGSTEVAKILQKTVAKRLSPSGHPIPLIAETGGQNAMIVDSSALTEQVVIDVLNSAFDSAGQRCSALRILCVQEDNSKTL
VTMLKGAMQQLIMGNPFLLKTDIGPVIDLEAKQTIDQHIQKMRSKGYPVYQLIFNHEAASQAQLSQGTFVTPTLIELPNL
DDLEREVFGPVLHVITYKHGEIKQLLQHINAKGYGLTMGLHTRIDETINTVVQHAEVGNLYINRNIVGAVVGVQPFGGEG
LSGTGPKAGGPLYLYRLMASCTEKAIQTPFGIPAENVAVPLTQLSLFREFSAWIKKQYPAHQLPNVVPLNVGHAFDLQGP
TGETNRYMMLPRKRILAIASNELELCHQMLAIFAVNSQVALLESNPSLQKFGQDLPTVVRQAIIEIRGVEHGDFDAVLHH
GSTEELQVLQTQIANRQGPIVGITHLQNSEQVIPLERLVIEHAISVNTAAAGGNASLMTMSE
>Mature_1261_residues
SLEFGMNMMDNDPQMDTAKPHFGYISEFKEKTELEQHINDAWRRPEPETVETLLQAASISDELNHKIYELAFELANGLRE
RKTSSGKAGIVQGLLQEFSLSSQEGIALMCLAEALLRIPDAATRDLLIRDKINQGNWKDHVGQSSLMFVNAAAWGLMLTG
KLMETPKQGSLSGLLTSILARSGRGVIRKAVDVAMRMMGEQFVTGETIEEALDNAKSHEHKGFRYSYDMLGEAALTTHDA
ERYFNDYTQAIHAIGQASNGKGVYDGPGISIKLSALHPRYQRSQIARVHDELYGKVFNLALLSKKYDIGLNIDAEEADRL
EISLELLERLCFEPELADWKGIGFVIQAYQKRCFYVVDYVVDLAKRSKKRLMIRLVKGAYWDSEIKKAQIDGMHDYPVFT
RKVHTDLSYIACAKKLLAAPEQIYPQFATHNAQSLATIYELADPGKYYAGQYEFQCLHGMGEPLYEQVVGSRSDKKLGIP
CRIYAPVGNHETLLAYLVRRLLENGANTSFVNRIADQNLKIEDLIQSPFDEIAINAQREGQAGLKHPAIPLPHNLYGSLR
QNSKGFDLANDATLTALNETAQQLEHKVWESRPLLAQTVDQIDVSPQALLNPAVHLDIVGYVQEATLEQVDVALESATQA
QQAWANTEKNHRAATLKKAANLMESRMQELMVLLCREAGKTYANAISEVREAVDFLRYYATQIESLKPTAQIEPLGTVLC
ISPWNFPLAIFTGQIAAALGAGNCVIAKPAEQTPLIAAQAVHILHEAGIPKSVLQLLPGRGETVGAKLSSDQRIQGVMFT
GSTEVAKILQKTVAKRLSPSGHPIPLIAETGGQNAMIVDSSALTEQVVIDVLNSAFDSAGQRCSALRILCVQEDNSKTLV
TMLKGAMQQLIMGNPFLLKTDIGPVIDLEAKQTIDQHIQKMRSKGYPVYQLIFNHEAASQAQLSQGTFVTPTLIELPNLD
DLEREVFGPVLHVITYKHGEIKQLLQHINAKGYGLTMGLHTRIDETINTVVQHAEVGNLYINRNIVGAVVGVQPFGGEGL
SGTGPKAGGPLYLYRLMASCTEKAIQTPFGIPAENVAVPLTQLSLFREFSAWIKKQYPAHQLPNVVPLNVGHAFDLQGPT
GETNRYMMLPRKRILAIASNELELCHQMLAIFAVNSQVALLESNPSLQKFGQDLPTVVRQAIIEIRGVEHGDFDAVLHHG
STEELQVLQTQIANRQGPIVGITHLQNSEQVIPLERLVIEHAISVNTAAAGGNASLMTMSE

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=492, Percent_Identity=32.3170731707317, Blast_Score=191, Evalue=5e-48,
Organism=Homo sapiens, GI25777734, Length=492, Percent_Identity=32.3170731707317, Blast_Score=191, Evalue=5e-48,
Organism=Homo sapiens, GI238859541, Length=492, Percent_Identity=32.3170731707317, Blast_Score=190, Evalue=8e-48,
Organism=Homo sapiens, GI21361176, Length=469, Percent_Identity=30.7036247334755, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI153266822, Length=462, Percent_Identity=30.3030303030303, Blast_Score=185, Evalue=3e-46,
Organism=Homo sapiens, GI25777732, Length=459, Percent_Identity=29.1938997821351, Blast_Score=176, Evalue=2e-43,
Organism=Homo sapiens, GI25777724, Length=463, Percent_Identity=29.5896328293737, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI25777730, Length=462, Percent_Identity=29.004329004329, Blast_Score=161, Evalue=5e-39,
Organism=Homo sapiens, GI25777728, Length=421, Percent_Identity=29.4536817102138, Blast_Score=160, Evalue=5e-39,
Organism=Homo sapiens, GI238814322, Length=429, Percent_Identity=27.7389277389277, Blast_Score=158, Evalue=4e-38,
Organism=Homo sapiens, GI21614513, Length=437, Percent_Identity=28.1464530892449, Blast_Score=156, Evalue=2e-37,
Organism=Homo sapiens, GI4507229, Length=422, Percent_Identity=29.6208530805687, Blast_Score=144, Evalue=7e-34,
Organism=Homo sapiens, GI12007648, Length=436, Percent_Identity=25.4587155963303, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI115387104, Length=454, Percent_Identity=26.2114537444934, Blast_Score=138, Evalue=3e-32,
Organism=Homo sapiens, GI188035924, Length=464, Percent_Identity=25.8620689655172, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI25777721, Length=435, Percent_Identity=28.735632183908, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI310128093, Length=450, Percent_Identity=26, Blast_Score=134, Evalue=6e-31,
Organism=Homo sapiens, GI310128103, Length=450, Percent_Identity=26, Blast_Score=134, Evalue=6e-31,
Organism=Homo sapiens, GI11095441, Length=427, Percent_Identity=25.7611241217799, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI25777726, Length=459, Percent_Identity=25.9259259259259, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI310128091, Length=392, Percent_Identity=27.2959183673469, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI25952152, Length=244, Percent_Identity=29.5081967213115, Blast_Score=108, Evalue=5e-23,
Organism=Homo sapiens, GI4502043, Length=348, Percent_Identity=25, Blast_Score=104, Evalue=5e-22,
Organism=Homo sapiens, GI238814371, Length=348, Percent_Identity=25, Blast_Score=104, Evalue=5e-22,
Organism=Homo sapiens, GI71773324, Length=348, Percent_Identity=25, Blast_Score=104, Evalue=6e-22,
Organism=Homo sapiens, GI310128087, Length=283, Percent_Identity=26.8551236749117, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI206597441, Length=441, Percent_Identity=24.0362811791383, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI206597439, Length=441, Percent_Identity=24.0362811791383, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI22907049, Length=441, Percent_Identity=24.0362811791383, Blast_Score=100, Evalue=9e-21,
Organism=Homo sapiens, GI4557303, Length=390, Percent_Identity=22.8205128205128, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI73466520, Length=390, Percent_Identity=22.8205128205128, Blast_Score=95, Evalue=4e-19,
Organism=Homo sapiens, GI73695881, Length=335, Percent_Identity=23.8805970149254, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI73695879, Length=335, Percent_Identity=23.8805970149254, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI310128089, Length=334, Percent_Identity=26.6467065868263, Blast_Score=90, Evalue=1e-17,
Organism=Homo sapiens, GI310128095, Length=320, Percent_Identity=27.1875, Blast_Score=84, Evalue=8e-16,
Organism=Homo sapiens, GI310128097, Length=269, Percent_Identity=28.2527881040892, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI310128101, Length=215, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI310128099, Length=215, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI301500698, Length=432, Percent_Identity=20.3703703703704, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1787250, Length=1258, Percent_Identity=59.5389507154213, Blast_Score=1460, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=465, Percent_Identity=29.4623655913978, Blast_Score=171, Evalue=3e-43,
Organism=Escherichia coli, GI1786504, Length=454, Percent_Identity=28.6343612334802, Blast_Score=169, Evalue=9e-43,
Organism=Escherichia coli, GI1787715, Length=453, Percent_Identity=30.242825607064, Blast_Score=164, Evalue=2e-41,
Organism=Escherichia coli, GI1787684, Length=462, Percent_Identity=28.3549783549784, Blast_Score=161, Evalue=3e-40,
Organism=Escherichia coli, GI1788042, Length=453, Percent_Identity=29.3598233995585, Blast_Score=156, Evalue=8e-39,
Organism=Escherichia coli, GI87081896, Length=494, Percent_Identity=28.9473684210526, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI1787558, Length=466, Percent_Identity=29.8283261802575, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI87082295, Length=439, Percent_Identity=28.4738041002278, Blast_Score=151, Evalue=3e-37,
Organism=Escherichia coli, GI87081926, Length=451, Percent_Identity=25.0554323725055, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI1787653, Length=399, Percent_Identity=23.5588972431078, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI133930964, Length=572, Percent_Identity=26.2237762237762, Blast_Score=172, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17562198, Length=459, Percent_Identity=29.6296296296296, Blast_Score=168, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17534447, Length=471, Percent_Identity=29.2993630573248, Blast_Score=167, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI25144435, Length=460, Percent_Identity=30.2173913043478, Blast_Score=165, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI25143874, Length=438, Percent_Identity=28.310502283105, Blast_Score=160, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI25143876, Length=438, Percent_Identity=28.310502283105, Blast_Score=159, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI32564736, Length=419, Percent_Identity=30.7875894988067, Blast_Score=156, Evalue=5e-38,
Organism=Caenorhabditis elegans, GI115534176, Length=509, Percent_Identity=27.5049115913556, Blast_Score=156, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI115532534, Length=395, Percent_Identity=29.3670886075949, Blast_Score=146, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17551164, Length=443, Percent_Identity=27.313769751693, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17534119, Length=473, Percent_Identity=27.061310782241, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71986308, Length=452, Percent_Identity=25.8849557522124, Blast_Score=130, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71995606, Length=448, Percent_Identity=25.8928571428571, Blast_Score=126, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32564151, Length=411, Percent_Identity=26.5206812652068, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71995613, Length=404, Percent_Identity=25.4950495049505, Blast_Score=122, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=268, Percent_Identity=29.8507462686567, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25146391, Length=343, Percent_Identity=24.7813411078717, Blast_Score=98, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=343, Percent_Identity=24.7813411078717, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=343, Percent_Identity=24.7813411078717, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=339, Percent_Identity=26.5486725663717, Blast_Score=93, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321826, Length=504, Percent_Identity=30.5555555555556, Blast_Score=178, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6325196, Length=453, Percent_Identity=30.9050772626932, Blast_Score=174, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6320917, Length=466, Percent_Identity=29.3991416309013, Blast_Score=164, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6323821, Length=461, Percent_Identity=28.6334056399132, Blast_Score=156, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6319478, Length=451, Percent_Identity=27.0509977827051, Blast_Score=154, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6323822, Length=464, Percent_Identity=28.448275862069, Blast_Score=152, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6324950, Length=458, Percent_Identity=26.4192139737991, Blast_Score=144, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6321828, Length=485, Percent_Identity=24.3298969072165, Blast_Score=116, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323757, Length=331, Percent_Identity=23.8670694864048, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362580, Length=452, Percent_Identity=28.7610619469027, Blast_Score=167, Evalue=5e-41,
Organism=Drosophila melanogaster, GI62472918, Length=452, Percent_Identity=28.7610619469027, Blast_Score=167, Evalue=5e-41,
Organism=Drosophila melanogaster, GI62472926, Length=452, Percent_Identity=28.7610619469027, Blast_Score=167, Evalue=5e-41,
Organism=Drosophila melanogaster, GI62472936, Length=452, Percent_Identity=28.7610619469027, Blast_Score=167, Evalue=5e-41,
Organism=Drosophila melanogaster, GI21356737, Length=452, Percent_Identity=28.7610619469027, Blast_Score=167, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24668425, Length=472, Percent_Identity=28.1779661016949, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24668417, Length=472, Percent_Identity=28.1779661016949, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24668413, Length=472, Percent_Identity=28.1779661016949, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24650465, Length=473, Percent_Identity=28.9640591966173, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI20129399, Length=462, Percent_Identity=28.1385281385281, Blast_Score=160, Evalue=5e-39,
Organism=Drosophila melanogaster, GI24585660, Length=516, Percent_Identity=25.3875968992248, Blast_Score=150, Evalue=5e-36,
Organism=Drosophila melanogaster, GI28571806, Length=454, Percent_Identity=26.8722466960352, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571802, Length=454, Percent_Identity=26.8722466960352, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571800, Length=454, Percent_Identity=26.8722466960352, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571798, Length=457, Percent_Identity=27.1334792122538, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571796, Length=457, Percent_Identity=27.1334792122538, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28571794, Length=457, Percent_Identity=27.1334792122538, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28574525, Length=500, Percent_Identity=26.2, Blast_Score=143, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24666674, Length=452, Percent_Identity=28.0973451327434, Blast_Score=136, Evalue=8e-32,
Organism=Drosophila melanogaster, GI281360299, Length=342, Percent_Identity=30.1169590643275, Blast_Score=117, Evalue=6e-26,
Organism=Drosophila melanogaster, GI281360297, Length=342, Percent_Identity=30.1169590643275, Blast_Score=117, Evalue=6e-26,
Organism=Drosophila melanogaster, GI281360295, Length=342, Percent_Identity=30.1169590643275, Blast_Score=117, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24586250, Length=342, Percent_Identity=30.1169590643275, Blast_Score=117, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24638876, Length=441, Percent_Identity=25.6235827664399, Blast_Score=116, Evalue=9e-26,
Organism=Drosophila melanogaster, GI281360301, Length=342, Percent_Identity=30.1169590643275, Blast_Score=116, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24638878, Length=441, Percent_Identity=25.6235827664399, Blast_Score=116, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45552499, Length=342, Percent_Identity=28.9473684210526, Blast_Score=109, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281360303, Length=342, Percent_Identity=28.9473684210526, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281360293, Length=166, Percent_Identity=33.7349397590361, Blast_Score=79, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 139144; Mature: 139013

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLEFGMNMMDNDPQMDTAKPHFGYISEFKEKTELEQHINDAWRRPEPETVETLLQAASI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SDELNHKIYELAFELANGLRERKTSSGKAGIVQGLLQEFSLSSQEGIALMCLAEALLRIP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
DAATRDLLIRDKINQGNWKDHVGQSSLMFVNAAAWGLMLTGKLMETPKQGSLSGLLTSIL
CCHHHCEEEEECCCCCCCHHHCCCCCEEEEEHHHHHHHHCCHHHCCCCCCCHHHHHHHHH
ARSGRGVIRKAVDVAMRMMGEQFVTGETIEEALDNAKSHEHKGFRYSYDMLGEAALTTHD
HHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHCCHHHHHHH
AERYFNDYTQAIHAIGQASNGKGVYDGPGISIKLSALHPRYQRSQIARVHDELYGKVFNL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ALLSKKYDIGLNIDAEEADRLEISLELLERLCFEPELADWKGIGFVIQAYQKRCFYVVDY
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VVDLAKRSKKRLMIRLVKGAYWDSEIKKAQIDGMHDYPVFTRKVHTDLSYIACAKKLLAA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PEQIYPQFATHNAQSLATIYELADPGKYYAGQYEFQCLHGMGEPLYEQVVGSRSDKKLGI
CHHHCHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCC
PCRIYAPVGNHETLLAYLVRRLLENGANTSFVNRIADQNLKIEDLIQSPFDEIAINAQRE
CEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHCCHHHHEECCCCC
GQAGLKHPAIPLPHNLYGSLRQNSKGFDLANDATLTALNETAQQLEHKVWESRPLLAQTV
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
DQIDVSPQALLNPAVHLDIVGYVQEATLEQVDVALESATQAQQAWANTEKNHRAATLKKA
HHHCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ANLMESRMQELMVLLCREAGKTYANAISEVREAVDFLRYYATQIESLKPTAQIEPLGTVL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
CISPWNFPLAIFTGQIAAALGAGNCVIAKPAEQTPLIAAQAVHILHEAGIPKSVLQLLPG
EECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCC
RGETVGAKLSSDQRIQGVMFTGSTEVAKILQKTVAKRLSPSGHPIPLIAETGGQNAMIVD
CCCEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEE
SSALTEQVVIDVLNSAFDSAGQRCSALRILCVQEDNSKTLVTMLKGAMQQLIMGNPFLLK
CHHHHHHHHHHHHHHHHHHHCCHHCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEE
TDIGPVIDLEAKQTIDQHIQKMRSKGYPVYQLIFNHEAASQAQLSQGTFVTPTLIELPNL
ECCCCEEECHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCHHEECCCC
DDLEREVFGPVLHVITYKHGEIKQLLQHINAKGYGLTMGLHTRIDETINTVVQHAEVGNL
CHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCE
YINRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLMASCTEKAIQTPFGIPAENVAVP
EECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
LTQLSLFREFSAWIKKQYPAHQLPNVVPLNVGHAFDLQGPTGETNRYMMLPRKRILAIAS
HHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCEEECCCCCCCCCCEEECCHHHHHHHHC
NELELCHQMLAIFAVNSQVALLESNPSLQKFGQDLPTVVRQAIIEIRGVEHGDFDAVLHH
CHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCC
GSTEELQVLQTQIANRQGPIVGITHLQNSEQVIPLERLVIEHAISVNTAAAGGNASLMTM
CCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
SE
CC
>Mature Secondary Structure 
SLEFGMNMMDNDPQMDTAKPHFGYISEFKEKTELEQHINDAWRRPEPETVETLLQAASI
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SDELNHKIYELAFELANGLRERKTSSGKAGIVQGLLQEFSLSSQEGIALMCLAEALLRIP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC
DAATRDLLIRDKINQGNWKDHVGQSSLMFVNAAAWGLMLTGKLMETPKQGSLSGLLTSIL
CCHHHCEEEEECCCCCCCHHHCCCCCEEEEEHHHHHHHHCCHHHCCCCCCCHHHHHHHHH
ARSGRGVIRKAVDVAMRMMGEQFVTGETIEEALDNAKSHEHKGFRYSYDMLGEAALTTHD
HHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHCCHHHHHHH
AERYFNDYTQAIHAIGQASNGKGVYDGPGISIKLSALHPRYQRSQIARVHDELYGKVFNL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
ALLSKKYDIGLNIDAEEADRLEISLELLERLCFEPELADWKGIGFVIQAYQKRCFYVVDY
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
VVDLAKRSKKRLMIRLVKGAYWDSEIKKAQIDGMHDYPVFTRKVHTDLSYIACAKKLLAA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
PEQIYPQFATHNAQSLATIYELADPGKYYAGQYEFQCLHGMGEPLYEQVVGSRSDKKLGI
CHHHCHHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCCCC
PCRIYAPVGNHETLLAYLVRRLLENGANTSFVNRIADQNLKIEDLIQSPFDEIAINAQRE
CEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHCCHHHHEECCCCC
GQAGLKHPAIPLPHNLYGSLRQNSKGFDLANDATLTALNETAQQLEHKVWESRPLLAQTV
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
DQIDVSPQALLNPAVHLDIVGYVQEATLEQVDVALESATQAQQAWANTEKNHRAATLKKA
HHHCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ANLMESRMQELMVLLCREAGKTYANAISEVREAVDFLRYYATQIESLKPTAQIEPLGTVL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
CISPWNFPLAIFTGQIAAALGAGNCVIAKPAEQTPLIAAQAVHILHEAGIPKSVLQLLPG
EECCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCC
RGETVGAKLSSDQRIQGVMFTGSTEVAKILQKTVAKRLSPSGHPIPLIAETGGQNAMIVD
CCCEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEE
SSALTEQVVIDVLNSAFDSAGQRCSALRILCVQEDNSKTLVTMLKGAMQQLIMGNPFLLK
CHHHHHHHHHHHHHHHHHHHCCHHCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEE
TDIGPVIDLEAKQTIDQHIQKMRSKGYPVYQLIFNHEAASQAQLSQGTFVTPTLIELPNL
ECCCCEEECHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCHHEECCCC
DDLEREVFGPVLHVITYKHGEIKQLLQHINAKGYGLTMGLHTRIDETINTVVQHAEVGNL
CHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCE
YINRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLMASCTEKAIQTPFGIPAENVAVP
EECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHH
LTQLSLFREFSAWIKKQYPAHQLPNVVPLNVGHAFDLQGPTGETNRYMMLPRKRILAIAS
HHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCEEECCCCCCCCCCEEECCHHHHHHHHC
NELELCHQMLAIFAVNSQVALLESNPSLQKFGQDLPTVVRQAIIEIRGVEHGDFDAVLHH
CHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHCC
GSTEELQVLQTQIANRQGPIVGITHLQNSEQVIPLERLVIEHAISVNTAAAGGNASLMTM
CCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEE
SE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]