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The map label for this gene is uppP

Identifier: 50084800

GI number: 50084800

Start: 1638583

End: 1639383

Strand: Reverse

Name: uppP

Synonym: ACIAD1642

Alternate gene names: 50084800

Gene position: 1639383-1638583 (Counterclockwise)

Preceding gene: 50084801

Following gene: 50084796

Centisome position: 45.56

GC content: 38.33

Gene sequence:

>801_bases
ATGGGAAATATTGAAGCTTTTAAAGCACTTTTTTTGGGTTTTATTGAAGGTTTAACTGAATTTTTACCTATCTCTAGCAC
TGGACATTTGATTTTATTTGGCCACCTTATTGATTTTCACTCTGATAGTGGTCGTGCTTTTGAAGTGGTTATTCAGCTTG
GTGCAATTTTGGCTGTATGTTGGCTGTATAGAAAAAAAATTATCGATCTGGTGCAAGGCTTCTTTAGTGGAGACCAAGAA
GCTCGACACTTTACCTTTAGTGTGTTGATGGCTTTTTTTCCTGCGGTCATTATTGGTGTATTGGCGGTAGACTTTATTAA
ATCTGTTTTATTTAGCCCATTAGTGGTTGCGATTGCGCTCATCATTGGCGGTTTAATTATTTTTTGGGTTGAGTCTAGAG
ATTTCAAACCCTCTACAACAGAAGCCACAAAAATTACATTCAAACAGGCCATTGCTGTCGGTTTTATTCAGTGTTTAGCC
ATGATTCCTGGTACATCTCGATCTGGTGCAACAATTATTGGCGGTATGCTCTCAGGTCTTTCCAGAAAAGCAGCAACAGA
ATTTTCCTTCTTTCTTGCGATGCCAACAATGTTAGGTGCTGCCACTTATGATTTGCTACGTAATGCGGATGTGCTCACCT
CTGATAATATGTTAAATATTGGCTTAGGATTTATTACCGCATTTATTTCTGCCTTGTTTGTGGTAAAAGCTCTTGTACGC
TTCGTCGAGAAACACACCCTGAGAGTATTTGCATGGTATCGAATCGTTCTGGGGATTATTATTATGTTTGTTATGCTATA
A

Upstream 100 bases:

>100_bases
ACGTTTCTGCTATGACATAATGATTTTAGCCAGAAAATTTTTTGGAATGATATTAGGCAATTTCACACTCGATTAAATTC
ATACATGAGTAAAATCTTAC

Downstream 100 bases:

>100_bases
AGCGTATGAAAAAGCTCAGATCATTCTGAGCTTTTTAAGACTGCTTAAATTGCGATCAGCTTTACCAGAATATTCTGTGA
CTCTTCAATTTCATCATAGT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 3; Undecaprenyl pyrophosphate phosphatase 3

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MGNIEAFKALFLGFIEGLTEFLPISSTGHLILFGHLIDFHSDSGRAFEVVIQLGAILAVCWLYRKKIIDLVQGFFSGDQE
ARHFTFSVLMAFFPAVIIGVLAVDFIKSVLFSPLVVAIALIIGGLIIFWVESRDFKPSTTEATKITFKQAIAVGFIQCLA
MIPGTSRSGATIIGGMLSGLSRKAATEFSFFLAMPTMLGAATYDLLRNADVLTSDNMLNIGLGFITAFISALFVVKALVR
FVEKHTLRVFAWYRIVLGIIIMFVML

Sequences:

>Translated_266_residues
MGNIEAFKALFLGFIEGLTEFLPISSTGHLILFGHLIDFHSDSGRAFEVVIQLGAILAVCWLYRKKIIDLVQGFFSGDQE
ARHFTFSVLMAFFPAVIIGVLAVDFIKSVLFSPLVVAIALIIGGLIIFWVESRDFKPSTTEATKITFKQAIAVGFIQCLA
MIPGTSRSGATIIGGMLSGLSRKAATEFSFFLAMPTMLGAATYDLLRNADVLTSDNMLNIGLGFITAFISALFVVKALVR
FVEKHTLRVFAWYRIVLGIIIMFVML
>Mature_265_residues
GNIEAFKALFLGFIEGLTEFLPISSTGHLILFGHLIDFHSDSGRAFEVVIQLGAILAVCWLYRKKIIDLVQGFFSGDQEA
RHFTFSVLMAFFPAVIIGVLAVDFIKSVLFSPLVVAIALIIGGLIIFWVESRDFKPSTTEATKITFKQAIAVGFIQCLAM
IPGTSRSGATIIGGMLSGLSRKAATEFSFFLAMPTMLGAATYDLLRNADVLTSDNMLNIGLGFITAFISALFVVKALVRF
VEKHTLRVFAWYRIVLGIIIMFVML

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=256, Percent_Identity=44.140625, Blast_Score=206, Evalue=1e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP3_ACIAD (Q6FBS3)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046310.1
- STRING:   Q6FBS3
- GeneID:   2878064
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1642
- NMPDR:   fig|62977.3.peg.1456
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   IGHFIGF
- PhylomeDB:   Q6FBS3
- ProtClustDB:   PRK00281
- BioCyc:   ASP62977:ACIAD1642-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29179; Mature: 29048

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x168cdf6c)-; HASH(0x185085e0)-; HASH(0x184f6d44)-; HASH(0x15221020)-; HASH(0x1850f348)-; HASH(0x1840e974)-; HASH(0x17c50eb0)-; HASH(0x187e4500)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure 
GNIEAFKALFLGFIEGLTEFLPISSTGHLILFGHLIDFHSDSGRAFEVVIQLGAILAVC
CCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHH
WLYRKKIIDLVQGFFSGDQEARHFTFSVLMAFFPAVIIGVLAVDFIKSVLFSPLVVAIAL
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGGLIIFWVESRDFKPSTTEATKITFKQAIAVGFIQCLAMIPGTSRSGATIIGGMLSGL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
SRKAATEFSFFLAMPTMLGAATYDLLRNADVLTSDNMLNIGLGFITAFISALFVVKALVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FVEKHTLRVFAWYRIVLGIIIMFVML
HHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA