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The map label for this gene is rssA [H]

Identifier: 50084598

GI number: 50084598

Start: 1415826

End: 1417133

Strand: Reverse

Name: rssA [H]

Synonym: ACIAD1421

Alternate gene names: 50084598

Gene position: 1417133-1415826 (Counterclockwise)

Preceding gene: 50084599

Following gene: 50084597

Centisome position: 39.38

GC content: 36.09

Gene sequence:

>1308_bases
ATGTCTTGGAGCATTTCAATATTTAGTATTTTTTTATTGATTTTTATTGGTGTAGCGGCCTACCGTATTGCACTGGAAGA
ATCCCAGGAAGTGATTGATCGACAAATGCAGGAAATGGCCGAGTTTCTGGATAAGAACTCGCTTTCTTTACGTTTGTCGA
CCTACGATCCAAATGCACATTATGATGAAACAGATGTGTTTATCGATATCATTAAACATGATCAGCTTAATCCACTCAGT
CAACACTATAATTATATTTTGCCGTATTCATCTACACCTTATTTCACCAAGAAAAAAACGACGCGTGGCGAACTAAGAAT
CTATATCTATCCCGCCAATGATAAACAGATTCAAATTAGCCAGTTGATTAAAGTCCGTAGACATCTCGCTAAAGAACTGG
CATTTAACATGCTGATTCCTTATATCTTTTTTATGCCATTTGCCATTTATAGCATGTATTTATTAATTCGTCATCATTTA
CGGAAATTAACAGAGCTGCGTACTACATTTTCAGAACGTGATTACAATGACTTATCTGAAATTCAGATTGAAAACCTACC
CATCGAGATTCGACCAGCTATAGATGAATTAAATTATCTATTTAAACGAATTGAACAGGCTAAAATTCAACAACAAGTAT
TTATCGCAAATGCAGCGCATGAACTTAGAACACCTTTAACAGCACTTAAATTACAAACTTCATTGCTTTTGAAAACACCA
CAAGACAGTCAAATTTATGATGAAAATTTGAGTGATCTGAGTTTAAGTTTAAAACGTATGACTCATTTAGTCGATCAGTT
AATGAGTCTAGCTCATCAAGAAGTCCATCAAGATGAACCTCTCCGATTATTAAATCTGGTGGCTCATATCAGACTTTGCG
TAGGACAACTTTTAGCCAATGCTCGCAAAAAAGATATTGAACTACAAGTCAATATTGAAGATGATCTGGAAGAAATATCA
ATTCTGGCAACAACCAATTCTTTACACAGCATCCTTATTAATTTGATTGATAATGCAATCAAATACAGCCCTCAACAAGG
TCAAGTCATCATTCTGCTGTCGCAAGATACAAATGCTGTTTATGTTGATATTCACGATAACGGGCCAGGTATTTCTGAAC
AAGAGTACGATCATGTATTAGAGCGTTTTGTTCGACTCGAACATACTCAACAACAGGCCATTGGAAGTGGCCTCGGTTTA
TCGATTGTACAATCTGCCTTAGATTCAGTTGATGCCAAGATGCAATTTAAGCCCTCACAGCTATTGGGCGGGCTTTGTGT
GCATTTAACCTTTAAACATAGTCTTTAA

Upstream 100 bases:

>100_bases
GGCTATTGTGTTGAAACTCAAGAAAAATAAGTTCATTCGTTTCAGACATGACTTAAAACGGATTAAGCAATTTTATCAAG
AGAAACCTCTAAGTCTGCGC

Downstream 100 bases:

>100_bases
GATTAATTCAAGCCATGTTTTCAAAACATTATTGAATGATGAAAAAAATGAAGGTTTTAATACTTGTTTAGCATATTTGT
TATGTTATAACATAACAAAT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MSWSISIFSIFLLIFIGVAAYRIALEESQEVIDRQMQEMAEFLDKNSLSLRLSTYDPNAHYDETDVFIDIIKHDQLNPLS
QHYNYILPYSSTPYFTKKKTTRGELRIYIYPANDKQIQISQLIKVRRHLAKELAFNMLIPYIFFMPFAIYSMYLLIRHHL
RKLTELRTTFSERDYNDLSEIQIENLPIEIRPAIDELNYLFKRIEQAKIQQQVFIANAAHELRTPLTALKLQTSLLLKTP
QDSQIYDENLSDLSLSLKRMTHLVDQLMSLAHQEVHQDEPLRLLNLVAHIRLCVGQLLANARKKDIELQVNIEDDLEEIS
ILATTNSLHSILINLIDNAIKYSPQQGQVIILLSQDTNAVYVDIHDNGPGISEQEYDHVLERFVRLEHTQQQAIGSGLGL
SIVQSALDSVDAKMQFKPSQLLGGLCVHLTFKHSL

Sequences:

>Translated_435_residues
MSWSISIFSIFLLIFIGVAAYRIALEESQEVIDRQMQEMAEFLDKNSLSLRLSTYDPNAHYDETDVFIDIIKHDQLNPLS
QHYNYILPYSSTPYFTKKKTTRGELRIYIYPANDKQIQISQLIKVRRHLAKELAFNMLIPYIFFMPFAIYSMYLLIRHHL
RKLTELRTTFSERDYNDLSEIQIENLPIEIRPAIDELNYLFKRIEQAKIQQQVFIANAAHELRTPLTALKLQTSLLLKTP
QDSQIYDENLSDLSLSLKRMTHLVDQLMSLAHQEVHQDEPLRLLNLVAHIRLCVGQLLANARKKDIELQVNIEDDLEEIS
ILATTNSLHSILINLIDNAIKYSPQQGQVIILLSQDTNAVYVDIHDNGPGISEQEYDHVLERFVRLEHTQQQAIGSGLGL
SIVQSALDSVDAKMQFKPSQLLGGLCVHLTFKHSL
>Mature_434_residues
SWSISIFSIFLLIFIGVAAYRIALEESQEVIDRQMQEMAEFLDKNSLSLRLSTYDPNAHYDETDVFIDIIKHDQLNPLSQ
HYNYILPYSSTPYFTKKKTTRGELRIYIYPANDKQIQISQLIKVRRHLAKELAFNMLIPYIFFMPFAIYSMYLLIRHHLR
KLTELRTTFSERDYNDLSEIQIENLPIEIRPAIDELNYLFKRIEQAKIQQQVFIANAAHELRTPLTALKLQTSLLLKTPQ
DSQIYDENLSDLSLSLKRMTHLVDQLMSLAHQEVHQDEPLRLLNLVAHIRLCVGQLLANARKKDIELQVNIEDDLEEISI
LATTNSLHSILINLIDNAIKYSPQQGQVIILLSQDTNAVYVDIHDNGPGISEQEYDHVLERFVRLEHTQQQAIGSGLGLS
IVQSALDSVDAKMQFKPSQLLGGLCVHLTFKHSL

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=418, Percent_Identity=28.9473684210526, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1790551, Length=285, Percent_Identity=28.7719298245614, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786600, Length=215, Percent_Identity=26.9767441860465, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788279, Length=298, Percent_Identity=27.1812080536913, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=225, Percent_Identity=28.8888888888889, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=26.1061946902655, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789808, Length=295, Percent_Identity=23.3898305084746, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=26.8085106382979, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790346, Length=249, Percent_Identity=24.8995983935743, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1789149, Length=300, Percent_Identity=25.3333333333333, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787894, Length=302, Percent_Identity=24.1721854304636, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1790861, Length=184, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI48994928, Length=207, Percent_Identity=25.1207729468599, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50198; Mature: 50066

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWSISIFSIFLLIFIGVAAYRIALEESQEVIDRQMQEMAEFLDKNSLSLRLSTYDPNAH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
YDETDVFIDIIKHDQLNPLSQHYNYILPYSSTPYFTKKKTTRGELRIYIYPANDKQIQIS
CCCHHHHHEEHHCCCCCCHHHCCCEEECCCCCCCEECCCCCCCCEEEEEEECCCCEEHHH
QLIKVRRHLAKELAFNMLIPYIFFMPFAIYSMYLLIRHHLRKLTELRTTFSERDYNDLSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IQIENLPIEIRPAIDELNYLFKRIEQAKIQQQVFIANAAHELRTPLTALKLQTSLLLKTP
EEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEECC
QDSQIYDENLSDLSLSLKRMTHLVDQLMSLAHQEVHQDEPLRLLNLVAHIRLCVGQLLAN
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
ARKKDIELQVNIEDDLEEISILATTNSLHSILINLIDNAIKYSPQQGQVIILLSQDTNAV
CCCCCCEEEEEEHHCHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEE
YVDIHDNGPGISEQEYDHVLERFVRLEHTQQQAIGSGLGLSIVQSALDSVDAKMQFKPSQ
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHH
LLGGLCVHLTFKHSL
HHCCHHEEEEEECCC
>Mature Secondary Structure 
SWSISIFSIFLLIFIGVAAYRIALEESQEVIDRQMQEMAEFLDKNSLSLRLSTYDPNAH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
YDETDVFIDIIKHDQLNPLSQHYNYILPYSSTPYFTKKKTTRGELRIYIYPANDKQIQIS
CCCHHHHHEEHHCCCCCCHHHCCCEEECCCCCCCEECCCCCCCCEEEEEEECCCCEEHHH
QLIKVRRHLAKELAFNMLIPYIFFMPFAIYSMYLLIRHHLRKLTELRTTFSERDYNDLSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
IQIENLPIEIRPAIDELNYLFKRIEQAKIQQQVFIANAAHELRTPLTALKLQTSLLLKTP
EEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEECC
QDSQIYDENLSDLSLSLKRMTHLVDQLMSLAHQEVHQDEPLRLLNLVAHIRLCVGQLLAN
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
ARKKDIELQVNIEDDLEEISILATTNSLHSILINLIDNAIKYSPQQGQVIILLSQDTNAV
CCCCCCEEEEEEHHCHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEE
YVDIHDNGPGISEQEYDHVLERFVRLEHTQQQAIGSGLGLSIVQSALDSVDAKMQFKPSQ
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHH
LLGGLCVHLTFKHSL
HHCCHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA