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The map label for this gene is iscU [H]

Identifier: 50084580

GI number: 50084580

Start: 1397567

End: 1397953

Strand: Reverse

Name: iscU [H]

Synonym: ACIAD1403

Alternate gene names: 50084580

Gene position: 1397953-1397567 (Counterclockwise)

Preceding gene: 50084581

Following gene: 50084579

Centisome position: 38.85

GC content: 40.05

Gene sequence:

>387_bases
ATGGCTTATAGCGAAAAGGTAATTGACCATTACGAAAATCCACGTAATGTCGGTATTTTAGATAAAAATGCTGAAAATGT
TGGTACAGGTATGGTAGGCGCGCCAGCGTGTGGTGATGTCATGCGTTTACAAATCCAAGTAAATAATGATGGTGTGATCG
AAGAAGCACGTTTCAAAACTTATGGTTGTGGCTCTGCGATTGCTTCAAGTTCATTAGTGACAGAATGGCTTAAAGGTAAA
ACACTTGATCAAGCGCAAGCGATCAAAAATATCGACATTGCAAATGAACTTGCTTTGCCACCTGTGAAAGTGCACTGTTC
TGTACTTGCAGAAGATGCCATTAAAGCGGCGATTGAAGACTATCGTAACAAACGATCAAAAGCTTAA

Upstream 100 bases:

>100_bases
TTTCTACAGTTGAATGGGCTGAACACTAATTTTTATTTGAAATCGGTGTTTTTAACCTCATATTTAATATTAGGCTGACC
CCGAGGTTTGGAGAAGCAAC

Downstream 100 bases:

>100_bases
CTAATACTGACCAGATGGAGTTTTCATGATTCACTTAACTGAAACTGCTGCAAATCATGTACGCAATTATCTACTTAACC
GTGGTAAAGGCGAAGGCATT

Product: scaffold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MAYSEKVIDHYENPRNVGILDKNAENVGTGMVGAPACGDVMRLQIQVNNDGVIEEARFKTYGCGSAIASSSLVTEWLKGK
TLDQAQAIKNIDIANELALPPVKVHCSVLAEDAIKAAIEDYRNKRSKA

Sequences:

>Translated_128_residues
MAYSEKVIDHYENPRNVGILDKNAENVGTGMVGAPACGDVMRLQIQVNNDGVIEEARFKTYGCGSAIASSSLVTEWLKGK
TLDQAQAIKNIDIANELALPPVKVHCSVLAEDAIKAAIEDYRNKRSKA
>Mature_127_residues
AYSEKVIDHYENPRNVGILDKNAENVGTGMVGAPACGDVMRLQIQVNNDGVIEEARFKTYGCGSAIASSSLVTEWLKGKT
LDQAQAIKNIDIANELALPPVKVHCSVLAEDAIKAAIEDYRNKRSKA

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=123, Percent_Identity=73.1707317073171, Blast_Score=198, Evalue=8e-52,
Organism=Homo sapiens, GI24307953, Length=122, Percent_Identity=72.9508196721311, Blast_Score=195, Evalue=1e-50,
Organism=Escherichia coli, GI1788878, Length=125, Percent_Identity=82.4, Blast_Score=224, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17543474, Length=125, Percent_Identity=71.2, Blast_Score=194, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6325122, Length=124, Percent_Identity=70.9677419354839, Blast_Score=188, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324800, Length=124, Percent_Identity=69.3548387096774, Blast_Score=186, Evalue=1e-48,
Organism=Drosophila melanogaster, GI21355597, Length=125, Percent_Identity=68.8, Blast_Score=188, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011339
- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 13847; Mature: 13716

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSEKVIDHYENPRNVGILDKNAENVGTGMVGAPACGDVMRLQIQVNNDGVIEEARFKT
CCCCHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCC
YGCGSAIASSSLVTEWLKGKTLDQAQAIKNIDIANELALPPVKVHCSVLAEDAIKAAIED
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHH
YRNKRSKA
HHHHCCCC
>Mature Secondary Structure 
AYSEKVIDHYENPRNVGILDKNAENVGTGMVGAPACGDVMRLQIQVNNDGVIEEARFKT
CCCHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEECCCCCC
YGCGSAIASSSLVTEWLKGKTLDQAQAIKNIDIANELALPPVKVHCSVLAEDAIKAAIED
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHH
YRNKRSKA
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]