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The map label for this gene is hscB

Identifier: 50084578

GI number: 50084578

Start: 1396621

End: 1397136

Strand: Reverse

Name: hscB

Synonym: ACIAD1400

Alternate gene names: 50084578

Gene position: 1397136-1396621 (Counterclockwise)

Preceding gene: 50084579

Following gene: 50084577

Centisome position: 38.82

GC content: 35.66

Gene sequence:

>516_bases
ATGAATCATTTTGAGTTGTTCGACTTACCCGTAGCACTCGACATTGATTTGGTCGCGTTAAAAGCAAATTTTCTTAAATT
GCAACAGCTACACCACCCAGATAAAGCATTGGATAAAGATCAAGCGCTTATAATGTCAAGTGATATTAATCAAGCCTATA
AAATCCTTTCGCAGGTGGACAGTCGCGCTGCCTATTTACTGTCTTTAAAAAAACAGGATCATCATTTAGACCAATCTATT
CATGATTTTGAATTTTTACAATCAGCATTAGAAATAAGAGAACAACTGGACGAAGCCGACTCTCAAGAACAGTTGATTAC
TCTGAAAAATGAAGTCAAACAGTGGGTTGATGGTCTAATTCGTGAATTTAAAATAGATTATTCAGATGAAGATTGGTCAG
AAGCACGTGATACCGTTCGAAAATTACGATTCTTTCAACGTGTGCTTAATGATATCGATAAAGCCGAAGATCAGTTACTT
GATGAAGATAGTTTTGATCTAGATGACGACTTTTAA

Upstream 100 bases:

>100_bases
ATCATTTACCGTTTAATCAAATTATCCTCCCTTCTTCTGAATTAAAAACAGTGATCTTCACTGTTTTTAATTTATTAATT
TACGATGGAATTCGTCTCCC

Downstream 100 bases:

>100_bases
TTTTGCTGTATAGATTTATTCAAGGGATTAAACATGGCACTCTTGCAAATTGCTGAACCTGGTCAATCAAGTGCCCCTCA
CGAACATCGCATTGCGATCG

Product: co-chaperone protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MNHFELFDLPVALDIDLVALKANFLKLQQLHHPDKALDKDQALIMSSDINQAYKILSQVDSRAAYLLSLKKQDHHLDQSI
HDFEFLQSALEIREQLDEADSQEQLITLKNEVKQWVDGLIREFKIDYSDEDWSEARDTVRKLRFFQRVLNDIDKAEDQLL
DEDSFDLDDDF

Sequences:

>Translated_171_residues
MNHFELFDLPVALDIDLVALKANFLKLQQLHHPDKALDKDQALIMSSDINQAYKILSQVDSRAAYLLSLKKQDHHLDQSI
HDFEFLQSALEIREQLDEADSQEQLITLKNEVKQWVDGLIREFKIDYSDEDWSEARDTVRKLRFFQRVLNDIDKAEDQLL
DEDSFDLDDDF
>Mature_171_residues
MNHFELFDLPVALDIDLVALKANFLKLQQLHHPDKALDKDQALIMSSDINQAYKILSQVDSRAAYLLSLKKQDHHLDQSI
HDFEFLQSALEIREQLDEADSQEQLITLKNEVKQWVDGLIREFKIDYSDEDWSEARDTVRKLRFFQRVLNDIDKAEDQLL
DEDSFDLDDDF

Specific function: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward hscA

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Escherichia coli, GI1788876, Length=170, Percent_Identity=37.0588235294118, Blast_Score=86, Evalue=1e-18,
Organism=Drosophila melanogaster, GI161084223, Length=166, Percent_Identity=27.710843373494, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSCB_ACIAD (Q6FCE5)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046088.1
- HSSP:   P0A6L9
- ProteinModelPortal:   Q6FCE5
- SMR:   Q6FCE5
- STRING:   Q6FCE5
- GeneID:   2878285
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1400
- NMPDR:   fig|62977.3.peg.702
- eggNOG:   COG1076
- HOGENOM:   HBG751004
- OMA:   INDSESK
- PhylomeDB:   Q6FCE5
- ProtClustDB:   CLSK707303
- BioCyc:   ASP62977:ACIAD1400-MONOMER
- HAMAP:   MF_00682
- InterPro:   IPR001623
- InterPro:   IPR009073
- InterPro:   IPR004640
- InterPro:   IPR015609
- Gene3D:   G3DSA:1.10.287.110
- Gene3D:   G3DSA:1.20.1280.20
- PANTHER:   PTHR11821
- SMART:   SM00271
- TIGRFAMs:   TIGR00714

Pfam domain/function: PF00226 DnaJ; PF07743 HSCB_C; SSF46565 DnaJ_N; SSF47144 HSC20_C

EC number: NA

Molecular weight: Translated: 20122; Mature: 20122

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHFELFDLPVALDIDLVALKANFLKLQQLHHPDKALDKDQALIMSSDINQAYKILSQVD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
SRAAYLLSLKKQDHHLDQSIHDFEFLQSALEIREQLDEADSQEQLITLKNEVKQWVDGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
REFKIDYSDEDWSEARDTVRKLRFFQRVLNDIDKAEDQLLDEDSFDLDDDF
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNHFELFDLPVALDIDLVALKANFLKLQQLHHPDKALDKDQALIMSSDINQAYKILSQVD
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
SRAAYLLSLKKQDHHLDQSIHDFEFLQSALEIREQLDEADSQEQLITLKNEVKQWVDGLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
REFKIDYSDEDWSEARDTVRKLRFFQRVLNDIDKAEDQLLDEDSFDLDDDF
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA