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The map label for this gene is gpsA

Identifier: 50084499

GI number: 50084499

Start: 1315685

End: 1316758

Strand: Direct

Name: gpsA

Synonym: ACIAD1317

Alternate gene names: 50084499

Gene position: 1315685-1316758 (Clockwise)

Preceding gene: 50084498

Following gene: 50084500

Centisome position: 36.56

GC content: 42.36

Gene sequence:

>1074_bases
ATGACCGATTTAAAATTTACTGATCTCGTTGAACCTGTCGTAATTGATAAAAAGACAGCATTGCGTGTTACTGTGCTGGG
CGGTGGTAGTTTTGGCACTGCTATGGCTAATCTGGCAACACGTAATGGTTGTAATACCATGATCTGGATACGTGATCAGA
AAATGGCAGACGAAATTAATCAAACGCATTTTAATCAGCGCTATTTACCCGATTTTAATTTAGAGCCAGAATTAAAGGCG
GTGAGTGATCTCGAATTGGCTGTACGTGATCGCGATATTATTTTTGTGGCTATTCCGAGTCATTCATTTCGTGAGGTGGT
GAAACAGATTTCACCTTATATCACGGCACAGGCTATTGTTTCACTGACTAAAGGTATTGAGGCAAATACGTTTAGTTTTA
TGAGCGATATTATTCGCGAAGAATTGCCTGAAGTGCCTTACGGTGTGCTGTCTGGCCCAAATTTGGCTAAGGAAATTGTG
GCAGGTATGCCTTCGGGTACGGTTATTGCAAGTGATTCTGAGCTGGTTCGTTATGCTGTTCAGCATGCGCTACACAGTGC
TTTATTCCGTGTATTTGGCAGTGATGATGTACATGGTGTTGAGCTGGGTGGAGCGCTTAAAAATATCTACGCGATCGCGA
TGGGCATGGCAGCCGCTTATAATATTGGTGAAAATACCAAAAGTATGATTATTACACGGGCTTTGGCAGAAATGAGCCGT
TTCGCAGTTAAGTTGGGTGCTAACCCATTGACCTTTTTAGGTTTGTCAGGTGTCGGTGATCTGTTTGCAACCTGTAATAG
TCCTTTGAGTCGTAACTATCAAATTGGATATGCATTGGGTTCTGGCAAAACACTTGATCAGGCCATTAAAGCTTTAGGTC
AAACGGCTGAGGGGATTAATACCATTGTTCAAGTACGGACGAGAGCAATCGAACTAGATGTGTATATGCCAATTACCAAT
GCATTGTATGAAGTTATTTTTGAGGGCGCACCACCGCTCAATATTGCACTGGCATTGATGAAAAATGGGCATCGCAGTGA
TGTGGAATTTGTATTGCCACATCATCAAGTTTGA

Upstream 100 bases:

>100_bases
TGCCAAAGCAATTGCACCCCGTACAGAAATTGATCTACATAATTTTGTAAAACAATGGTCAGCACAATAAAATAAATTGC
CAGAACACTTAGGAACAAGA

Downstream 100 bases:

>100_bases
CGGATAAATGTAACAAACTATCGTTATAATCAATCGATATTAAACAAGGAAATTTTATGCAACTTACGCTTGTTCGTCAT
GGTGAGGCTTCACCAGCGAT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MTDLKFTDLVEPVVIDKKTALRVTVLGGGSFGTAMANLATRNGCNTMIWIRDQKMADEINQTHFNQRYLPDFNLEPELKA
VSDLELAVRDRDIIFVAIPSHSFREVVKQISPYITAQAIVSLTKGIEANTFSFMSDIIREELPEVPYGVLSGPNLAKEIV
AGMPSGTVIASDSELVRYAVQHALHSALFRVFGSDDVHGVELGGALKNIYAIAMGMAAAYNIGENTKSMIITRALAEMSR
FAVKLGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLDQAIKALGQTAEGINTIVQVRTRAIELDVYMPITN
ALYEVIFEGAPPLNIALALMKNGHRSDVEFVLPHHQV

Sequences:

>Translated_357_residues
MTDLKFTDLVEPVVIDKKTALRVTVLGGGSFGTAMANLATRNGCNTMIWIRDQKMADEINQTHFNQRYLPDFNLEPELKA
VSDLELAVRDRDIIFVAIPSHSFREVVKQISPYITAQAIVSLTKGIEANTFSFMSDIIREELPEVPYGVLSGPNLAKEIV
AGMPSGTVIASDSELVRYAVQHALHSALFRVFGSDDVHGVELGGALKNIYAIAMGMAAAYNIGENTKSMIITRALAEMSR
FAVKLGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLDQAIKALGQTAEGINTIVQVRTRAIELDVYMPITN
ALYEVIFEGAPPLNIALALMKNGHRSDVEFVLPHHQV
>Mature_356_residues
TDLKFTDLVEPVVIDKKTALRVTVLGGGSFGTAMANLATRNGCNTMIWIRDQKMADEINQTHFNQRYLPDFNLEPELKAV
SDLELAVRDRDIIFVAIPSHSFREVVKQISPYITAQAIVSLTKGIEANTFSFMSDIIREELPEVPYGVLSGPNLAKEIVA
GMPSGTVIASDSELVRYAVQHALHSALFRVFGSDDVHGVELGGALKNIYAIAMGMAAAYNIGENTKSMIITRALAEMSRF
AVKLGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLDQAIKALGQTAEGINTIVQVRTRAIELDVYMPITNA
LYEVIFEGAPPLNIALALMKNGHRSDVEFVLPHHQV

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=336, Percent_Identity=31.25, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI33695088, Length=333, Percent_Identity=29.7297297297297, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI1790037, Length=328, Percent_Identity=39.0243902439024, Blast_Score=233, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI32564399, Length=338, Percent_Identity=28.9940828402367, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI193210136, Length=347, Percent_Identity=28.5302593659942, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI32564403, Length=347, Percent_Identity=28.5302593659942, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17507425, Length=305, Percent_Identity=28.8524590163934, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193210134, Length=333, Percent_Identity=26.7267267267267, Blast_Score=78, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6324513, Length=360, Percent_Identity=30, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320181, Length=349, Percent_Identity=28.9398280802292, Blast_Score=113, Evalue=6e-26,
Organism=Drosophila melanogaster, GI22026922, Length=288, Percent_Identity=32.6388888888889, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17136202, Length=335, Percent_Identity=31.044776119403, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136200, Length=335, Percent_Identity=31.044776119403, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136204, Length=335, Percent_Identity=31.044776119403, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45551945, Length=261, Percent_Identity=26.8199233716475, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI281362270, Length=261, Percent_Identity=26.8199233716475, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648969, Length=221, Percent_Identity=28.9592760180996, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_ACIAD (Q3V7H1)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046009.1
- HSSP:   Q8N1B0
- ProteinModelPortal:   Q3V7H1
- SMR:   Q3V7H1
- STRING:   Q3V7H1
- GeneID:   2878143
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1317
- NMPDR:   fig|62977.3.peg.491
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- PhylomeDB:   Q3V7H1
- ProtClustDB:   PRK00094
- BioCyc:   ASP62977:ACIAD1317-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 38800; Mature: 38669

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 207-207 BINDING 124-124 BINDING 124-124 BINDING 156-156 BINDING 271-271 BINDING 297-297

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLKFTDLVEPVVIDKKTALRVTVLGGGSFGTAMANLATRNGCNTMIWIRDQKMADEIN
CCCCCHHHCCCHHEECCCCEEEEEEEECCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHH
QTHFNQRYLPDFNLEPELKAVSDLELAVRDRDIIFVAIPSHSFREVVKQISPYITAQAIV
HHHCCCCCCCCCCCCCCHHHHHHHHEEEECCCEEEEEECCHHHHHHHHHHCHHHHHHHHH
SLTKGIEANTFSFMSDIIREELPEVPYGVLSGPNLAKEIVAGMPSGTVIASDSELVRYAV
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCHHHHHHHH
QHALHSALFRVFGSDDVHGVELGGALKNIYAIAMGMAAAYNIGENTKSMIITRALAEMSR
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FAVKLGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLDQAIKALGQTAEGIN
HHHHHCCCCEEEEECCCHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHH
TIVQVRTRAIELDVYMPITNALYEVIFEGAPPLNIALALMKNGHRSDVEFVLPHHQV
HHHHHHHHEEEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEECCCCCC
>Mature Secondary Structure 
TDLKFTDLVEPVVIDKKTALRVTVLGGGSFGTAMANLATRNGCNTMIWIRDQKMADEIN
CCCCHHHCCCHHEECCCCEEEEEEEECCCHHHHHHHHHHCCCCCEEEEEECHHHHHHHH
QTHFNQRYLPDFNLEPELKAVSDLELAVRDRDIIFVAIPSHSFREVVKQISPYITAQAIV
HHHCCCCCCCCCCCCCCHHHHHHHHEEEECCCEEEEEECCHHHHHHHHHHCHHHHHHHHH
SLTKGIEANTFSFMSDIIREELPEVPYGVLSGPNLAKEIVAGMPSGTVIASDSELVRYAV
HHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCHHHHHHHH
QHALHSALFRVFGSDDVHGVELGGALKNIYAIAMGMAAAYNIGENTKSMIITRALAEMSR
HHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
FAVKLGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLDQAIKALGQTAEGIN
HHHHHCCCCEEEEECCCHHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHH
TIVQVRTRAIELDVYMPITNALYEVIFEGAPPLNIALALMKNGHRSDVEFVLPHHQV
HHHHHHHHEEEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA