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The map label for this gene is tas [H]

Identifier: 50084447

GI number: 50084447

Start: 1259438

End: 1260484

Strand: Reverse

Name: tas [H]

Synonym: ACIAD1261

Alternate gene names: 50084447

Gene position: 1260484-1259438 (Counterclockwise)

Preceding gene: 50084448

Following gene: 50084439

Centisome position: 35.03

GC content: 42.02

Gene sequence:

>1047_bases
ATGCGGTTTAACCCTCTTGGTCACACGGATATTCAGCTTCCCGAAATTTGTCTGGGAACCATGACTTTTGGCGAACAGAA
TTCACAGCCCGAAGCATTTGAACAACTCAATTATGCGCTTACAAATGGTTTGTATTTTTGGGATACGGCCGAAATGTATT
CAGTTCCGCCCAAGCCTGAAACATATGGAGCCACCGAAACAATTATTGGAAACTGGTTTGCACAACATGGACAAAGAGAC
CAAGTTTTTCTGGCATCCAAAATTGCAGGCCCTGGTTTTGGTGGAAGTCACATACGTGAAGGGAATACCCAATTTGGACA
ACACATTGCACAAGCCTTAGATGGCTCCCTTAAACGTTTACAAACCGACTATATTGATCTGTATCAATTACATTGGCCAG
AACGCCATACCAATTTTTTTGGTACTTTAGGCTATGGTAACGCCGAAGCAGCAAGCGATTATGAAGTTGAAGCGATGCAA
CAAACACTTCTTGCGTTACAAAAGGAGATTGATCGAGGACGTATCCGCTATATTGGCCTATCTAACGAAACGCCTTGGGG
CACCATGAAATTTCTGCAATTGGCAGAAAAGCTTGGTATCGATAAATTCGTTAGTATTCAAAACCCATACAATCTACTTA
ATCGTACCTATGAAATGGGGATGTCTGAAATTGCCAAATATGAAGGCATTGGATTACTGGCTTACTCACCACTCGCTTTT
GGTTATCTAACAGGGAAGTTCCGTCATGGCGCCCGACCTGCGAATGCTCGTGTTACTTTATTTTCACGCTTTACGCGTTA
TAGTAATCCACAAAGTGAATGGGCCACTGAACAATATGCCCAATTGGCAGAACAACATGGCTTGACTCTCACTCAACTGG
CACTGGCCTTTATCAAACAGCAGTTCTTTGTGACCAGTACCATTATTGGAGCAACTAGTGTTCAACAACTCAAAGAAGAT
ATACAGGCATTTGATATCATCTTGGATGATGCTGTATTAAAGGGTATTGAAGATATACATAAACAACAACCAAATCCAGC
ACCTTAA

Upstream 100 bases:

>100_bases
AGAAGCTTTCCAAAGATACGAAAAACTTATACGAACATATATCACCTTGTTTTAAATTGGACAGATATCTCATCTACCAG
ATCTATCAGGATTTTTCATT

Downstream 100 bases:

>100_bases
AATGAATACAGGATGTCATAAGACATCCTGTGTTTCTTACTAAAGCACCAAACTTAACGGCGATTATTATAAACAGCCAT
TGCTGCTGGTAAATTTTTTC

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MRFNPLGHTDIQLPEICLGTMTFGEQNSQPEAFEQLNYALTNGLYFWDTAEMYSVPPKPETYGATETIIGNWFAQHGQRD
QVFLASKIAGPGFGGSHIREGNTQFGQHIAQALDGSLKRLQTDYIDLYQLHWPERHTNFFGTLGYGNAEAASDYEVEAMQ
QTLLALQKEIDRGRIRYIGLSNETPWGTMKFLQLAEKLGIDKFVSIQNPYNLLNRTYEMGMSEIAKYEGIGLLAYSPLAF
GYLTGKFRHGARPANARVTLFSRFTRYSNPQSEWATEQYAQLAEQHGLTLTQLALAFIKQQFFVTSTIIGATSVQQLKED
IQAFDIILDDAVLKGIEDIHKQQPNPAP

Sequences:

>Translated_348_residues
MRFNPLGHTDIQLPEICLGTMTFGEQNSQPEAFEQLNYALTNGLYFWDTAEMYSVPPKPETYGATETIIGNWFAQHGQRD
QVFLASKIAGPGFGGSHIREGNTQFGQHIAQALDGSLKRLQTDYIDLYQLHWPERHTNFFGTLGYGNAEAASDYEVEAMQ
QTLLALQKEIDRGRIRYIGLSNETPWGTMKFLQLAEKLGIDKFVSIQNPYNLLNRTYEMGMSEIAKYEGIGLLAYSPLAF
GYLTGKFRHGARPANARVTLFSRFTRYSNPQSEWATEQYAQLAEQHGLTLTQLALAFIKQQFFVTSTIIGATSVQQLKED
IQAFDIILDDAVLKGIEDIHKQQPNPAP
>Mature_348_residues
MRFNPLGHTDIQLPEICLGTMTFGEQNSQPEAFEQLNYALTNGLYFWDTAEMYSVPPKPETYGATETIIGNWFAQHGQRD
QVFLASKIAGPGFGGSHIREGNTQFGQHIAQALDGSLKRLQTDYIDLYQLHWPERHTNFFGTLGYGNAEAASDYEVEAMQ
QTLLALQKEIDRGRIRYIGLSNETPWGTMKFLQLAEKLGIDKFVSIQNPYNLLNRTYEMGMSEIAKYEGIGLLAYSPLAF
GYLTGKFRHGARPANARVTLFSRFTRYSNPQSEWATEQYAQLAEQHGLTLTQLALAFIKQQFFVTSTIIGATSVQQLKED
IQAFDIILDDAVLKGIEDIHKQQPNPAP

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=355, Percent_Identity=27.0422535211268, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4504825, Length=353, Percent_Identity=26.9121813031161, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI27436964, Length=358, Percent_Identity=25.9776536312849, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI27436962, Length=358, Percent_Identity=25.9776536312849, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI27436966, Length=353, Percent_Identity=26.0623229461756, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI27436971, Length=339, Percent_Identity=27.1386430678466, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI223718702, Length=237, Percent_Identity=27.4261603375527, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI41152114, Length=331, Percent_Identity=24.4712990936556, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI41327764, Length=325, Percent_Identity=25.5384615384615, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789199, Length=349, Percent_Identity=49.5702005730659, Blast_Score=356, Evalue=1e-99,
Organism=Escherichia coli, GI87081735, Length=357, Percent_Identity=30.2521008403361, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789375, Length=340, Percent_Identity=27.3529411764706, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788070, Length=345, Percent_Identity=28.9855072463768, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788081, Length=340, Percent_Identity=27.0588235294118, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319958, Length=319, Percent_Identity=24.4514106583072, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323998, Length=347, Percent_Identity=25.0720461095101, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6325169, Length=362, Percent_Identity=24.8618784530387, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=288, Percent_Identity=24.3055555555556, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322615, Length=276, Percent_Identity=23.5507246376812, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39209; Mature: 39209

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFNPLGHTDIQLPEICLGTMTFGEQNSQPEAFEQLNYALTNGLYFWDTAEMYSVPPKPE
CCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEECHHHCCCCCCCC
TYGATETIIGNWFAQHGQRDQVFLASKIAGPGFGGSHIREGNTQFGQHIAQALDGSLKRL
CCCCHHHHHHHHHHHCCCCCCEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QTDYIDLYQLHWPERHTNFFGTLGYGNAEAASDYEVEAMQQTLLALQKEIDRGRIRYIGL
HHHHHHHHHEECCCHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEC
SNETPWGTMKFLQLAEKLGIDKFVSIQNPYNLLNRTYEMGMSEIAKYEGIGLLAYSPLAF
CCCCCCHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
GYLTGKFRHGARPANARVTLFSRFTRYSNPQSEWATEQYAQLAEQHGLTLTQLALAFIKQ
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QFFVTSTIIGATSVQQLKEDIQAFDIILDDAVLKGIEDIHKQQPNPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRFNPLGHTDIQLPEICLGTMTFGEQNSQPEAFEQLNYALTNGLYFWDTAEMYSVPPKPE
CCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEECHHHCCCCCCCC
TYGATETIIGNWFAQHGQRDQVFLASKIAGPGFGGSHIREGNTQFGQHIAQALDGSLKRL
CCCCHHHHHHHHHHHCCCCCCEEEEHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
QTDYIDLYQLHWPERHTNFFGTLGYGNAEAASDYEVEAMQQTLLALQKEIDRGRIRYIGL
HHHHHHHHHEECCCHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEC
SNETPWGTMKFLQLAEKLGIDKFVSIQNPYNLLNRTYEMGMSEIAKYEGIGLLAYSPLAF
CCCCCCHHHHHHHHHHHHCCHHEEECCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHH
GYLTGKFRHGARPANARVTLFSRFTRYSNPQSEWATEQYAQLAEQHGLTLTQLALAFIKQ
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QFFVTSTIIGATSVQQLKEDIQAFDIILDDAVLKGIEDIHKQQPNPAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9560382; 9278503 [H]