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The map label for this gene is hcr [C]

Identifier: 50084396

GI number: 50084396

Start: 1208687

End: 1209748

Strand: Direct

Name: hcr [C]

Synonym: ACIAD1207

Alternate gene names: 50084396

Gene position: 1208687-1209748 (Clockwise)

Preceding gene: 50084393

Following gene: 50084397

Centisome position: 33.59

GC content: 40.21

Gene sequence:

>1062_bases
ATGCAAGCAATTCAAAAGAGAACAACACGCTTACGTTCATTGACCAAGTCAGTGTTCGAACCGCATGCAACTGATTTCTG
GTTACAAAAAATTAATCCTATTTGGTCGACTCATTTAGCTCTTGCTAAAATTGTAGACAAAAAACAAGTTGCAAATGACA
CTGTATCTTTAACACTGCAACCCAATCGCCATGTCAATTTAGGTCGAGCTGGTCAGCATCATCCTGTTAAAGTTAAAATT
GCTGGTCGTATTTATGAGCGTAGTTACAGCTTGACAGAACGTCATGGTCAACTCATTTTAACTGTTAAAAAAGTCGCTGA
AGGTAAGGTGAGTGCTTGGTTGGTCGATCACAGCCAAATTGGCGATATTATTGAACTTGGACAACCTTTTGGGGAAATGC
AATTACAAGATCAGCAACGTTTGGTTTTGCTTGCAGCAGGTAGTGGTATCACGCCAATGCTCAGTTTGGTTGAAGCACTT
AAGCATCAACAGGCTTTAAATACAACGCAAGTTCAGCTTTTATACTGGGTGAAGCATCATGAAGATGCAGCCTATGCCCA
ATGGTTCGAAGCTCTGGCAAAGCAATTTCCTTTATTCCAGTTTCAAATTTTTTATACTCAAGATCAGGAGCATGATGGAC
GTCTTAACGTGACCCATCTTGCCGCTATTGATGATCTGGATCAAAGCACAGTATATGCCTGTGGGCCTTCTGGTTTTGTG
GCAAAAGCTGAAGAACTTTTTGCTCAGGCACAAGTATTCATGAGCGAAGCCTTTAGTTTAAGTACCGTAAGTGAAGACGA
GACTGGTTTTGTTAATGTCACCTTGAGTAAATCTAATAAAACGGTGGCAATTCCTAAAGGTCAATCTATATTGGCAGGTT
TAGAGCAAGCCAATGTAAAACTAACGTACGGTTGTCGTATGGGGATCTGTAATAAATGTGCGTGTCAGAAAGCACAAGGT
TCTACCAGGAATCTGCTGAATGCAAGTGAAAACTCAGAACCCAACAATCTTTTAAAAATCTGTGTGAACTCGGCTAAATC
TGATCTTGTTATTGATCTTTAA

Upstream 100 bases:

>100_bases
AGCTGCTTACGATTTGAAACGTAAATAAAAGTACAGGTGTATATACAAATTTATATACATGTGTATAATAATTAAAAAAG
CAGCACAGAGTAGTAGCATC

Downstream 100 bases:

>100_bases
TTGTGAGAACTCCCATGAACGCACCTGTAAAATTTGAATATTTTAAAAATCCCAAAAATAGAGAATTAACTGCGGTTGAA
CTTGAAGCATTTGCAAAAGA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MQAIQKRTTRLRSLTKSVFEPHATDFWLQKINPIWSTHLALAKIVDKKQVANDTVSLTLQPNRHVNLGRAGQHHPVKVKI
AGRIYERSYSLTERHGQLILTVKKVAEGKVSAWLVDHSQIGDIIELGQPFGEMQLQDQQRLVLLAAGSGITPMLSLVEAL
KHQQALNTTQVQLLYWVKHHEDAAYAQWFEALAKQFPLFQFQIFYTQDQEHDGRLNVTHLAAIDDLDQSTVYACGPSGFV
AKAEELFAQAQVFMSEAFSLSTVSEDETGFVNVTLSKSNKTVAIPKGQSILAGLEQANVKLTYGCRMGICNKCACQKAQG
STRNLLNASENSEPNNLLKICVNSAKSDLVIDL

Sequences:

>Translated_353_residues
MQAIQKRTTRLRSLTKSVFEPHATDFWLQKINPIWSTHLALAKIVDKKQVANDTVSLTLQPNRHVNLGRAGQHHPVKVKI
AGRIYERSYSLTERHGQLILTVKKVAEGKVSAWLVDHSQIGDIIELGQPFGEMQLQDQQRLVLLAAGSGITPMLSLVEAL
KHQQALNTTQVQLLYWVKHHEDAAYAQWFEALAKQFPLFQFQIFYTQDQEHDGRLNVTHLAAIDDLDQSTVYACGPSGFV
AKAEELFAQAQVFMSEAFSLSTVSEDETGFVNVTLSKSNKTVAIPKGQSILAGLEQANVKLTYGCRMGICNKCACQKAQG
STRNLLNASENSEPNNLLKICVNSAKSDLVIDL
>Mature_353_residues
MQAIQKRTTRLRSLTKSVFEPHATDFWLQKINPIWSTHLALAKIVDKKQVANDTVSLTLQPNRHVNLGRAGQHHPVKVKI
AGRIYERSYSLTERHGQLILTVKKVAEGKVSAWLVDHSQIGDIIELGQPFGEMQLQDQQRLVLLAAGSGITPMLSLVEAL
KHQQALNTTQVQLLYWVKHHEDAAYAQWFEALAKQFPLFQFQIFYTQDQEHDGRLNVTHLAAIDDLDQSTVYACGPSGFV
AKAEELFAQAQVFMSEAFSLSTVSEDETGFVNVTLSKSNKTVAIPKGQSILAGLEQANVKLTYGCRMGICNKCACQKAQG
STRNLLNASENSEPNNLLKICVNSAKSDLVIDL

Specific function: This is an electron transfer partner for desA3 [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=295, Percent_Identity=27.4576271186441, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1788903, Length=215, Percent_Identity=30.2325581395349, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787658, Length=351, Percent_Identity=24.2165242165242, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788104, Length=300, Percent_Identity=26.3333333333333, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322146, Length=188, Percent_Identity=31.9148936170213, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24655635, Length=231, Percent_Identity=27.7056277056277, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39222; Mature: 39222

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIQKRTTRLRSLTKSVFEPHATDFWLQKINPIWSTHLALAKIVDKKQVANDTVSLTLQ
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEC
PNRHVNLGRAGQHHPVKVKIAGRIYERSYSLTERHGQLILTVKKVAEGKVSAWLVDHSQI
CCCCCCCCCCCCCCCEEEEEECEEEHHCCHHHHCCCCEEEEEEHHHCCCEEEEEECHHHH
GDIIELGQPFGEMQLQDQQRLVLLAAGSGITPMLSLVEALKHQQALNTTQVQLLYWVKHH
CHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHEEEEEEEECC
EDAAYAQWFEALAKQFPLFQFQIFYTQDQEHDGRLNVTHLAAIDDLDQSTVYACGPSGFV
CCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEEEEEECCCCCCEEEEECCCCHH
AKAEELFAQAQVFMSEAFSLSTVSEDETGFVNVTLSKSNKTVAIPKGQSILAGLEQANVK
HHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHCCEE
LTYGCRMGICNKCACQKAQGSTRNLLNASENSEPNNLLKICVNSAKSDLVIDL
EEECCCCCCCCHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEC
>Mature Secondary Structure
MQAIQKRTTRLRSLTKSVFEPHATDFWLQKINPIWSTHLALAKIVDKKQVANDTVSLTLQ
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEEC
PNRHVNLGRAGQHHPVKVKIAGRIYERSYSLTERHGQLILTVKKVAEGKVSAWLVDHSQI
CCCCCCCCCCCCCCCEEEEEECEEEHHCCHHHHCCCCEEEEEEHHHCCCEEEEEECHHHH
GDIIELGQPFGEMQLQDQQRLVLLAAGSGITPMLSLVEALKHQQALNTTQVQLLYWVKHH
CHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCHHEEEEEEEECC
EDAAYAQWFEALAKQFPLFQFQIFYTQDQEHDGRLNVTHLAAIDDLDQSTVYACGPSGFV
CCHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEEEEEECCCCCCEEEEECCCCHH
AKAEELFAQAQVFMSEAFSLSTVSEDETGFVNVTLSKSNKTVAIPKGQSILAGLEQANVK
HHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHCCEE
LTYGCRMGICNKCACQKAQGSTRNLLNASENSEPNNLLKICVNSAKSDLVIDL
EEECCCCCCCCHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]