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The map label for this gene is mdtA [H]

Identifier: 50084348

GI number: 50084348

Start: 1148683

End: 1149891

Strand: Direct

Name: mdtA [H]

Synonym: ACIAD1157

Alternate gene names: 50084348

Gene position: 1148683-1149891 (Clockwise)

Preceding gene: 50084346

Following gene: 50084349

Centisome position: 31.92

GC content: 41.11

Gene sequence:

>1209_bases
ATGATAGAACAACCGTTAAATATTGAAAAAAAATCTCGAACTCTCCCAAAAAATACAAAATCGTTTGTGCTATGGGCAAT
TGTCATTATGGTGATTGCATTCGCAATTTACTGGTGGAAATTGAGCCAAGTTCCGACACAGGAATACAGCCAGTGGAGCA
AGCCTGTACCTGTCAGGGTGATATCTGTACAACGAAATGATTTACAGTTTGAAATTAAAGCGATTGGGACAGTGCTTCCC
ACGCATTTGGTAAAAGTGCAAAGTCAGGTAGCAGGTGTTTTACAAAAGATTTATTTTAAAGAAGGTCAATACGTCAGCAA
AGGTCAACTTCTGGTGCAAATTGACCCAGCGCCATTTCAGGTGGCTTTAGCTCAAGCACAAGGGACACAGCAACAAAATC
TTGCACAATTGCGTAATGCTGAGAGTGAACTGGCGCGCTATCAATTGTTGTTTAAACAGGACTCTATTGCCAGACAACAG
GTTGAACAGCAACAAGCGCTAGTCAATCAGCTCAAAGGTCAAGTTCAGGCCAATCAAGCGCAGGTTGATGCAGCGAAATT
ACAACTTTCCTATACCAAGATTTATGCGCCAATTGAAGGTCGAGTTGGTTTTAAACAAAAAGATACAGGCAATTTAATAC
AAGCCAATGAAGACGCAGGGTTGGTCAGCATTACACAGGTACATCCGATCTATGTCCAATTTGCAATCGCTGAAAACTAT
TTGGATATGTTACGCGCAAGTCTGCAAAAGGGAGAACAAGTCAAAGTCAGTGCTTGGGATCGTGCAGAGAAAAAACAACT
TGCGACTGGATATGTGGAGGCATTTGATAATCAGATCGATACCAATACAGGCACTTTAAAAATAAAAGCCACGTTTAAAA
ATCGTGATGATGCGTTATTTCCAAATCAGTTTGTCAATGTTCGTTTAAACGCTAAAACCATTCAAAATGCAATCAACATT
CCGACCGATGCGATTCAAAACGGCGCGAAAGGTACCTATGTGTATATCATTAATAAAGACAATAAGGCTGAAATTCGAAT
GCTTAAACTGGGTATGAGTTCGAATGGCCAGACCGAGATTTTAGAGGGATTACAAGGTAATGAACGTGTCGTTTTAGAGG
GAATTGATCGTCTTTCGGAGGGTAAAGAAGCTCAAGTGGTACAGGACGCCACCGTTTCATTGGCATCCACACAAACAGCA
CGTGGATAA

Upstream 100 bases:

>100_bases
AGTTAATACAAATGCAATTTTCGTCCAATTAAACATGCTTTTAAGGGGAAGCAGGATGAGGATGATTTGGCCTATATTGA
TAGCGATTTAAGTGAATGTA

Downstream 100 bases:

>100_bases
GTTCAATGAATATGTCGAGATTTTTTATTTTACGACCCGTTGCAACCACATTATTGATGCTGGCACTTTTGTTTAGTGGC
TTGATGATTTGGCGGTTCCT

Product: RND transporter, membrane fusion protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MIEQPLNIEKKSRTLPKNTKSFVLWAIVIMVIAFAIYWWKLSQVPTQEYSQWSKPVPVRVISVQRNDLQFEIKAIGTVLP
THLVKVQSQVAGVLQKIYFKEGQYVSKGQLLVQIDPAPFQVALAQAQGTQQQNLAQLRNAESELARYQLLFKQDSIARQQ
VEQQQALVNQLKGQVQANQAQVDAAKLQLSYTKIYAPIEGRVGFKQKDTGNLIQANEDAGLVSITQVHPIYVQFAIAENY
LDMLRASLQKGEQVKVSAWDRAEKKQLATGYVEAFDNQIDTNTGTLKIKATFKNRDDALFPNQFVNVRLNAKTIQNAINI
PTDAIQNGAKGTYVYIINKDNKAEIRMLKLGMSSNGQTEILEGLQGNERVVLEGIDRLSEGKEAQVVQDATVSLASTQTA
RG

Sequences:

>Translated_402_residues
MIEQPLNIEKKSRTLPKNTKSFVLWAIVIMVIAFAIYWWKLSQVPTQEYSQWSKPVPVRVISVQRNDLQFEIKAIGTVLP
THLVKVQSQVAGVLQKIYFKEGQYVSKGQLLVQIDPAPFQVALAQAQGTQQQNLAQLRNAESELARYQLLFKQDSIARQQ
VEQQQALVNQLKGQVQANQAQVDAAKLQLSYTKIYAPIEGRVGFKQKDTGNLIQANEDAGLVSITQVHPIYVQFAIAENY
LDMLRASLQKGEQVKVSAWDRAEKKQLATGYVEAFDNQIDTNTGTLKIKATFKNRDDALFPNQFVNVRLNAKTIQNAINI
PTDAIQNGAKGTYVYIINKDNKAEIRMLKLGMSSNGQTEILEGLQGNERVVLEGIDRLSEGKEAQVVQDATVSLASTQTA
RG
>Mature_402_residues
MIEQPLNIEKKSRTLPKNTKSFVLWAIVIMVIAFAIYWWKLSQVPTQEYSQWSKPVPVRVISVQRNDLQFEIKAIGTVLP
THLVKVQSQVAGVLQKIYFKEGQYVSKGQLLVQIDPAPFQVALAQAQGTQQQNLAQLRNAESELARYQLLFKQDSIARQQ
VEQQQALVNQLKGQVQANQAQVDAAKLQLSYTKIYAPIEGRVGFKQKDTGNLIQANEDAGLVSITQVHPIYVQFAIAENY
LDMLRASLQKGEQVKVSAWDRAEKKQLATGYVEAFDNQIDTNTGTLKIKATFKNRDDALFPNQFVNVRLNAKTIQNAINI
PTDAIQNGAKGTYVYIINKDNKAEIRMLKLGMSSNGQTEILEGLQGNERVVLEGIDRLSEGKEAQVVQDATVSLASTQTA
RG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=337, Percent_Identity=43.026706231454, Blast_Score=285, Evalue=3e-78,
Organism=Escherichia coli, GI1786668, Length=370, Percent_Identity=29.1891891891892, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789929, Length=323, Percent_Identity=26.9349845201238, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1789665, Length=321, Percent_Identity=28.6604361370716, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87081796, Length=388, Percent_Identity=23.9690721649485, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081951, Length=162, Percent_Identity=29.6296296296296, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44915; Mature: 44915

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEQPLNIEKKSRTLPKNTKSFVLWAIVIMVIAFAIYWWKLSQVPTQEYSQWSKPVPVRV
CCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEE
ISVQRNDLQFEIKAIGTVLPTHLVKVQSQVAGVLQKIYFKEGQYVSKGQLLVQIDPAPFQ
EEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCEE
VALAQAQGTQQQNLAQLRNAESELARYQLLFKQDSIARQQVEQQQALVNQLKGQVQANQA
EEEEHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QVDAAKLQLSYTKIYAPIEGRVGFKQKDTGNLIQANEDAGLVSITQVHPIYVQFAIAENY
HEEHHHEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCEEEEEEECEEEEEEEHHHHH
LDMLRASLQKGEQVKVSAWDRAEKKQLATGYVEAFDNQIDTNTGTLKIKATFKNRDDALF
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCC
PNQFVNVRLNAKTIQNAINIPTDAIQNGAKGTYVYIINKDNKAEIRMLKLGMSSNGQTEI
CCCEEEEEEEHHHHHHHHCCCHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCCHHHH
LEGLQGNERVVLEGIDRLSEGKEAQVVQDATVSLASTQTARG
HHCCCCCCEEEEEEHHHHCCCCCCEEHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIEQPLNIEKKSRTLPKNTKSFVLWAIVIMVIAFAIYWWKLSQVPTQEYSQWSKPVPVRV
CCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCEEE
ISVQRNDLQFEIKAIGTVLPTHLVKVQSQVAGVLQKIYFKEGQYVSKGQLLVQIDPAPFQ
EEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCCEE
VALAQAQGTQQQNLAQLRNAESELARYQLLFKQDSIARQQVEQQQALVNQLKGQVQANQA
EEEEHHCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
QVDAAKLQLSYTKIYAPIEGRVGFKQKDTGNLIQANEDAGLVSITQVHPIYVQFAIAENY
HEEHHHEEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCEEEEEEECEEEEEEEHHHHH
LDMLRASLQKGEQVKVSAWDRAEKKQLATGYVEAFDNQIDTNTGTLKIKATFKNRDDALF
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCC
PNQFVNVRLNAKTIQNAINIPTDAIQNGAKGTYVYIINKDNKAEIRMLKLGMSSNGQTEI
CCCEEEEEEEHHHHHHHHCCCHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCCHHHH
LEGLQGNERVVLEGIDRLSEGKEAQVVQDATVSLASTQTARG
HHCCCCCCEEEEEEHHHHCCCCCCEEHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA