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The map label for this gene is fadH [H]

Identifier: 50084346

GI number: 50084346

Start: 1145935

End: 1147965

Strand: Direct

Name: fadH [H]

Synonym: ACIAD1155

Alternate gene names: 50084346

Gene position: 1145935-1147965 (Clockwise)

Preceding gene: 50084345

Following gene: 50084348

Centisome position: 31.84

GC content: 43.53

Gene sequence:

>2031_bases
ATGACTAGCTATGCACATATTTTAAAACCTTTACATCTTGGTTTTACAACAATTAAAAATAGAGTTGTGATGGGCTCTAT
GCATACGGGCTTAGAAGATCGTTTCTATAATTATCCTAAACTCGCTGCTTACTTTGGTGAACGTGCTAAAGGAGGCGTTG
GTTTAATTATTACAGGTGGAATATCACCAAACCGTCAAGGTTGGCTATTGCCTGCGGGTGGAACCATGAATTCATTGGCC
GATATTCCGCATCATCGTTTAGTCACTCATGCAGTACACAAGCATGGGGGTAAAATTCTCATGCAGATATTGCATGCTGG
GCGTTATGGTTATCAGCCTTTTATCGTTTCTGCGAGTCCAATTAAATCTCCAATTTCTCCGTTCAAACCACGTCAGATGT
CCGAAAAAAATATTCTGGACACAATTGAAGATTATGCGCGTTGTAGTGAACTGGCAAAAAAAGCAGGGTATGACGGCATA
GAAATTATGGGATCTGAAGGCTATTTGCTCAATCAGTTTTTGAGCCGTCATGTCAATCAACGTGAAGACCGTTGGGGTGG
GGCTATCGAAAATCGCATGCGCTTTGCAATTGAAATTGTAAAGGCAATTCGAGAAAAGGTCGGTGAAAAATTTATCATCA
GTTTTCGTTTATCCATGTTGGATCTGGTGCATGACGGTAACACGATGCAGGAAGTCATTATTGTTGCTAAAGCTTTAGAA
AAGGTGGGTGTCACACTGTTAAATACAGGAATTGGCTGGCATGAGGCGCGTGTACCTACCATTGTGACCTCTGTACCACG
TGCAGCATTTGTAGATTATACCGCTTATGTAAAGCAGCATGTCACTATTCCAGTCATTGCTTCTAACCGGATTAATATGC
CAGATGTGGCAGAGAATATTCTTGCAACTGGTAAAGCCGATATGATTCAGATGGCACGCCCTTTACTGGCAGATGCTTTT
TGGGTGACCAAGGTGGCTACCAATCGGGTCGATGAAATCAATACTTGTATTGCCTGTAATCAGGCATGTTTGGACCATAC
CTTTAAAAACCAACGCGCGACCTGTTTGGTCAATCCACGAGCAGCGTATGAAACCGAACTCACCTATATCAAAACTAAAA
AGCCAAAGAAAATTGCAGTCGTGGGTGGTGGTGTTGCAGGCATGTCTGCTGCAACAGTTGCAGCGAGTCGTGGACATCAA
GTCACATTATTTGAAGCTTCTCATGACGTTGGGGGGCAGTTTAATTTGGCAAAAGTTGTACCTGGTAAAGAGGAATTTCA
TGAAACCATTCGATATTTTAAAGTCCAAATTGAAAAAACAGGCGTAGATTTACGCTTGAATACGCGCGTAAATCGTGAAC
AGCTAGAAAGAGAAGGTTTTGATGAGGTCATTGTCGCGACTGGGGTTATACCACGGCAGCTCAAAATTCAAGGAAGTGAT
GCACCTCAAGTATTATCTTATGCCGAGGTTCTTAAAGGAGCTTCTGTTGGCCATAAAGTGGCTGTGATTGGCGCTGGTGG
AATTGGTTTTGATGTTTCAGAGTTTCTACTTAGACCAGAGCATCAACCACAGCCACAACCGTTAGCGCAATGGCAGCGTG
AGTGGGGAATCGACCCGATGCCAGACTATATTACCGAAGGTGGATTAGTACCTACAGAGCTTGAACCGCCTGTACGCCAG
ATCTATTTATTACAGCGAAAAACAAGCCCATTGGGCGTTGGTTTAGGGAAAACATCGGGTTGGGTACATCGTGCACAACT
GAAAAAACATGCAGTTAGAATGATGCGGGGTGTACAATACAAAGCAGTGACTAATGAGGGCTTATGGATTGAGCTGGATG
GACATGACCAACTGTTACGTGTCGATACGATTGTGGTCTGTGCTGGTCAGGAATCGGTTAAAGATATAATGCCGAAAGAA
GATGAAAATACATTGGCCCATTATCACATTATTGGAGGAGCAAAGCTTGCAGCCGAACTAGATGCCAAACGTGCGATACG
TGAGGGTGCAGAATTGGCCGCTAAACTTTGA

Upstream 100 bases:

>100_bases
CAACACGCAAAAAAAGAAGCAAGGTCATCCCAACAAATCAAAAAAGTATTAAAGTACTATGCAACAAGTTGCAAAGCCAA
TAACATTTCAAGGATTCATC

Downstream 100 bases:

>100_bases
TTTTGATGAAACAATATGCAATTGAGTGTAAAGATCTAAAATTTTTCTTGAATAAAATGAAGTGACTTTGTATTCTTACG
CACATGGAAGCGTGGCAGAG

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 676; Mature: 675

Protein sequence:

>676_residues
MTSYAHILKPLHLGFTTIKNRVVMGSMHTGLEDRFYNYPKLAAYFGERAKGGVGLIITGGISPNRQGWLLPAGGTMNSLA
DIPHHRLVTHAVHKHGGKILMQILHAGRYGYQPFIVSASPIKSPISPFKPRQMSEKNILDTIEDYARCSELAKKAGYDGI
EIMGSEGYLLNQFLSRHVNQREDRWGGAIENRMRFAIEIVKAIREKVGEKFIISFRLSMLDLVHDGNTMQEVIIVAKALE
KVGVTLLNTGIGWHEARVPTIVTSVPRAAFVDYTAYVKQHVTIPVIASNRINMPDVAENILATGKADMIQMARPLLADAF
WVTKVATNRVDEINTCIACNQACLDHTFKNQRATCLVNPRAAYETELTYIKTKKPKKIAVVGGGVAGMSAATVAASRGHQ
VTLFEASHDVGGQFNLAKVVPGKEEFHETIRYFKVQIEKTGVDLRLNTRVNREQLEREGFDEVIVATGVIPRQLKIQGSD
APQVLSYAEVLKGASVGHKVAVIGAGGIGFDVSEFLLRPEHQPQPQPLAQWQREWGIDPMPDYITEGGLVPTELEPPVRQ
IYLLQRKTSPLGVGLGKTSGWVHRAQLKKHAVRMMRGVQYKAVTNEGLWIELDGHDQLLRVDTIVVCAGQESVKDIMPKE
DENTLAHYHIIGGAKLAAELDAKRAIREGAELAAKL

Sequences:

>Translated_676_residues
MTSYAHILKPLHLGFTTIKNRVVMGSMHTGLEDRFYNYPKLAAYFGERAKGGVGLIITGGISPNRQGWLLPAGGTMNSLA
DIPHHRLVTHAVHKHGGKILMQILHAGRYGYQPFIVSASPIKSPISPFKPRQMSEKNILDTIEDYARCSELAKKAGYDGI
EIMGSEGYLLNQFLSRHVNQREDRWGGAIENRMRFAIEIVKAIREKVGEKFIISFRLSMLDLVHDGNTMQEVIIVAKALE
KVGVTLLNTGIGWHEARVPTIVTSVPRAAFVDYTAYVKQHVTIPVIASNRINMPDVAENILATGKADMIQMARPLLADAF
WVTKVATNRVDEINTCIACNQACLDHTFKNQRATCLVNPRAAYETELTYIKTKKPKKIAVVGGGVAGMSAATVAASRGHQ
VTLFEASHDVGGQFNLAKVVPGKEEFHETIRYFKVQIEKTGVDLRLNTRVNREQLEREGFDEVIVATGVIPRQLKIQGSD
APQVLSYAEVLKGASVGHKVAVIGAGGIGFDVSEFLLRPEHQPQPQPLAQWQREWGIDPMPDYITEGGLVPTELEPPVRQ
IYLLQRKTSPLGVGLGKTSGWVHRAQLKKHAVRMMRGVQYKAVTNEGLWIELDGHDQLLRVDTIVVCAGQESVKDIMPKE
DENTLAHYHIIGGAKLAAELDAKRAIREGAELAAKL
>Mature_675_residues
TSYAHILKPLHLGFTTIKNRVVMGSMHTGLEDRFYNYPKLAAYFGERAKGGVGLIITGGISPNRQGWLLPAGGTMNSLAD
IPHHRLVTHAVHKHGGKILMQILHAGRYGYQPFIVSASPIKSPISPFKPRQMSEKNILDTIEDYARCSELAKKAGYDGIE
IMGSEGYLLNQFLSRHVNQREDRWGGAIENRMRFAIEIVKAIREKVGEKFIISFRLSMLDLVHDGNTMQEVIIVAKALEK
VGVTLLNTGIGWHEARVPTIVTSVPRAAFVDYTAYVKQHVTIPVIASNRINMPDVAENILATGKADMIQMARPLLADAFW
VTKVATNRVDEINTCIACNQACLDHTFKNQRATCLVNPRAAYETELTYIKTKKPKKIAVVGGGVAGMSAATVAASRGHQV
TLFEASHDVGGQFNLAKVVPGKEEFHETIRYFKVQIEKTGVDLRLNTRVNREQLEREGFDEVIVATGVIPRQLKIQGSDA
PQVLSYAEVLKGASVGHKVAVIGAGGIGFDVSEFLLRPEHQPQPQPLAQWQREWGIDPMPDYITEGGLVPTELEPPVRQI
YLLQRKTSPLGVGLGKTSGWVHRAQLKKHAVRMMRGVQYKAVTNEGLWIELDGHDQLLRVDTIVVCAGQESVKDIMPKED
ENTLAHYHIIGGAKLAAELDAKRAIREGAELAAKL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=678, Percent_Identity=51.9174041297935, Blast_Score=722, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=359, Percent_Identity=24.2339832869081, Blast_Score=89, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17565138, Length=227, Percent_Identity=25.1101321585903, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=274, Percent_Identity=25.9124087591241, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17564188, Length=256, Percent_Identity=25, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17540738, Length=288, Percent_Identity=25.3472222222222, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17566914, Length=247, Percent_Identity=26.7206477732794, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI72001454, Length=177, Percent_Identity=27.1186440677966, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559802, Length=175, Percent_Identity=29.7142857142857, Blast_Score=82, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325086, Length=235, Percent_Identity=28.0851063829787, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6321973, Length=259, Percent_Identity=27.027027027027, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 74642; Mature: 74511

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSYAHILKPLHLGFTTIKNRVVMGSMHTGLEDRFYNYPKLAAYFGERAKGGVGLIITGG
CCCHHHHHHHHHHHHHHHHCEEEEECHHCCHHHHHCCCCHHHHHHHHCCCCCEEEEEECC
ISPNRQGWLLPAGGTMNSLADIPHHRLVTHAVHKHGGKILMQILHAGRYGYQPFIVSASP
CCCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCC
IKSPISPFKPRQMSEKNILDTIEDYARCSELAKKAGYDGIEIMGSEGYLLNQFLSRHVNQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCC
REDRWGGAIENRMRFAIEIVKAIREKVGEKFIISFRLSMLDLVHDGNTMQEVIIVAKALE
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHH
KVGVTLLNTGIGWHEARVPTIVTSVPRAAFVDYTAYVKQHVTIPVIASNRINMPDVAENI
HHCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHH
LATGKADMIQMARPLLADAFWVTKVATNRVDEINTCIACNQACLDHTFKNQRATCLVNPR
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHCCCCCEEEECCC
AAYETELTYIKTKKPKKIAVVGGGVAGMSAATVAASRGHQVTLFEASHDVGGQFNLAKVV
CCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEC
PGKEEFHETIRYFKVQIEKTGVDLRLNTRVNREQLEREGFDEVIVATGVIPRQLKIQGSD
CCHHHHHHHHHHHEEEEEECCCEEEEECCCCHHHHHHCCCCCEEHCCCCCCCEEEECCCC
APQVLSYAEVLKGASVGHKVAVIGAGGIGFDVSEFLLRPEHQPQPQPLAQWQREWGIDPM
CHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCC
PDYITEGGLVPTELEPPVRQIYLLQRKTSPLGVGLGKTSGWVHRAQLKKHAVRMMRGVQY
CHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCEE
KAVTNEGLWIELDGHDQLLRVDTIVVCAGQESVKDIMPKEDENTLAHYHIIGGAKLAAEL
EEEECCCEEEEECCCCCEEEEEEEEEECCCHHHHHCCCCCCCCCEEEEEEECCHHHHHHH
DAKRAIREGAELAAKL
HHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSYAHILKPLHLGFTTIKNRVVMGSMHTGLEDRFYNYPKLAAYFGERAKGGVGLIITGG
CCHHHHHHHHHHHHHHHHCEEEEECHHCCHHHHHCCCCHHHHHHHHCCCCCEEEEEECC
ISPNRQGWLLPAGGTMNSLADIPHHRLVTHAVHKHGGKILMQILHAGRYGYQPFIVSASP
CCCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEECCC
IKSPISPFKPRQMSEKNILDTIEDYARCSELAKKAGYDGIEIMGSEGYLLNQFLSRHVNQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCC
REDRWGGAIENRMRFAIEIVKAIREKVGEKFIISFRLSMLDLVHDGNTMQEVIIVAKALE
HHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHH
KVGVTLLNTGIGWHEARVPTIVTSVPRAAFVDYTAYVKQHVTIPVIASNRINMPDVAENI
HHCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHH
LATGKADMIQMARPLLADAFWVTKVATNRVDEINTCIACNQACLDHTFKNQRATCLVNPR
HHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHCCCCCEEEECCC
AAYETELTYIKTKKPKKIAVVGGGVAGMSAATVAASRGHQVTLFEASHDVGGQFNLAKVV
CCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCCEEEEEEC
PGKEEFHETIRYFKVQIEKTGVDLRLNTRVNREQLEREGFDEVIVATGVIPRQLKIQGSD
CCHHHHHHHHHHHEEEEEECCCEEEEECCCCHHHHHHCCCCCEEHCCCCCCCEEEECCCC
APQVLSYAEVLKGASVGHKVAVIGAGGIGFDVSEFLLRPEHQPQPQPLAQWQREWGIDPM
CHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCCC
PDYITEGGLVPTELEPPVRQIYLLQRKTSPLGVGLGKTSGWVHRAQLKKHAVRMMRGVQY
CHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCEE
KAVTNEGLWIELDGHDQLLRVDTIVVCAGQESVKDIMPKEDENTLAHYHIIGGAKLAAEL
EEEECCCEEEEECCCCCEEEEEEEEEECCCHHHHHCCCCCCCCCEEEEEEECCHHHHHHH
DAKRAIREGAELAAKL
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]