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The map label for this gene is nfuA

Identifier: 50084252

GI number: 50084252

Start: 1044449

End: 1045087

Strand: Direct

Name: nfuA

Synonym: ACIAD1052

Alternate gene names: 50084252

Gene position: 1044449-1045087 (Clockwise)

Preceding gene: 50084249

Following gene: 50084253

Centisome position: 29.02

GC content: 43.04

Gene sequence:

>639_bases
ATGTCGACTGAGAACACCAGCACTGCGGTAGCAGAAGAAATTCCAAATCTTTTAATTACACCATCTGCACAAGAGTATTT
GGGTGATTTATTGGAAAAACAAAATACTCCAGGAATTGGCGTTCGTATCTTCGTTGAAAACCCAGGAACGCCACGTGCTG
AGTGCTGTATGGCTTATAGTGCACCAGATGAAGTAAATCCAGCCGATTACAAACAGGAATATTCTGATTTTCCTGCCTAC
ATCGATGCACCTTCAATTCCTTATTTGCTTGATGCAGTGATTGATTACAACAAAGACCGTTTTGGTGGTCAGCTTACTTT
TCGTGCACCAAACTCGAAAGTACCACGTGTAGGGCCTGATGCTTCAATTGAAGAACGAATCACTTATATACTTCAGTCTG
AAATCAATCCAGGCCTGGCAGGGCATGGCGGTAACTGTGCTTTAGTTGAAGTTCAAGATGATCCAGAAAATGGTTTAACG
GCTGTGCTTAAGTTTGGTGGCGGCTGTCAGGGCTGTTCAGCGATTGATGTAACTTTAAAGCAAGGCGTTGAAACCACATT
ACGTCAACAGATTCCTGAACTTCAGCGTGTAGTAGATCAGACTGACCATACACAGGCTGAAGGTGCTTACTTTAAGTAA

Upstream 100 bases:

>100_bases
AAAAATAGAATTTAAAACAAATCCGACAATTTTAGTTGATTTTTTTTAATTCCACCGCATCTTCAGTTAAGATAAGCACT
TCAGCTTGAGGATTATTGTT

Downstream 100 bases:

>100_bases
GTCAATTTAGTTTTAAAAAAAGCCTCTTTATTAAGAGGCTTTTTTTATTAGAAGATATTGATAATAATTCTCAATATTAT
TTGTAATTTAATTTATTTTT

Product: membrane-bound protein in GNT I transport system (GntY)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSTENTSTAVAEEIPNLLITPSAQEYLGDLLEKQNTPGIGVRIFVENPGTPRAECCMAYSAPDEVNPADYKQEYSDFPAY
IDAPSIPYLLDAVIDYNKDRFGGQLTFRAPNSKVPRVGPDASIEERITYILQSEINPGLAGHGGNCALVEVQDDPENGLT
AVLKFGGGCQGCSAIDVTLKQGVETTLRQQIPELQRVVDQTDHTQAEGAYFK

Sequences:

>Translated_212_residues
MSTENTSTAVAEEIPNLLITPSAQEYLGDLLEKQNTPGIGVRIFVENPGTPRAECCMAYSAPDEVNPADYKQEYSDFPAY
IDAPSIPYLLDAVIDYNKDRFGGQLTFRAPNSKVPRVGPDASIEERITYILQSEINPGLAGHGGNCALVEVQDDPENGLT
AVLKFGGGCQGCSAIDVTLKQGVETTLRQQIPELQRVVDQTDHTQAEGAYFK
>Mature_211_residues
STENTSTAVAEEIPNLLITPSAQEYLGDLLEKQNTPGIGVRIFVENPGTPRAECCMAYSAPDEVNPADYKQEYSDFPAYI
DAPSIPYLLDAVIDYNKDRFGGQLTFRAPNSKVPRVGPDASIEERITYILQSEINPGLAGHGGNCALVEVQDDPENGLTA
VLKFGGGCQGCSAIDVTLKQGVETTLRQQIPELQRVVDQTDHTQAEGAYFK

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family

Homologues:

Organism=Escherichia coli, GI1789819, Length=193, Percent_Identity=47.1502590673575, Blast_Score=185, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NFUA_ACIAD (Q6FDB8)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045762.1
- ProteinModelPortal:   Q6FDB8
- SMR:   Q6FDB8
- STRING:   Q6FDB8
- GeneID:   2880120
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1052
- eggNOG:   COG0694
- HOGENOM:   HBG289644
- OMA:   CQGCSAV
- PhylomeDB:   Q6FDB8
- ProtClustDB:   CLSK2307340
- BioCyc:   ASP62977:ACIAD1052-MONOMER
- HAMAP:   MF_01637
- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- ProDom:   PD002830
- TIGRFAMs:   TIGR03341

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 22998; Mature: 22867

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTENTSTAVAEEIPNLLITPSAQEYLGDLLEKQNTPGIGVRIFVENPGTPRAECCMAYS
CCCCCHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHEEEEC
APDEVNPADYKQEYSDFPAYIDAPSIPYLLDAVIDYNKDRFGGQLTFRAPNSKVPRVGPD
CCCCCCCHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCC
ASIEERITYILQSEINPGLAGHGGNCALVEVQDDPENGLTAVLKFGGGCQGCSAIDVTLK
CCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHH
QGVETTLRQQIPELQRVVDQTDHTQAEGAYFK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
STENTSTAVAEEIPNLLITPSAQEYLGDLLEKQNTPGIGVRIFVENPGTPRAECCMAYS
CCCCHHHHHHHHCCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHEEEEC
APDEVNPADYKQEYSDFPAYIDAPSIPYLLDAVIDYNKDRFGGQLTFRAPNSKVPRVGPD
CCCCCCCHHHHHHHHCCCCEECCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCC
ASIEERITYILQSEINPGLAGHGGNCALVEVQDDPENGLTAVLKFGGGCQGCSAIDVTLK
CCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHH
QGVETTLRQQIPELQRVVDQTDHTQAEGAYFK
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA