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The map label for this gene is dsdA

Identifier: 50084249

GI number: 50084249

Start: 1040556

End: 1041881

Strand: Direct

Name: dsdA

Synonym: ACIAD1048

Alternate gene names: 50084249

Gene position: 1040556-1041881 (Clockwise)

Preceding gene: 50084248

Following gene: 50084252

Centisome position: 28.92

GC content: 41.1

Gene sequence:

>1326_bases
ATGACTACATTAAATATTCAAGCCATACAACAAGATTCATTAATCAAGTCGCTAAAAAATTACGAAGAAATTTTTTGGTT
TCAGCCAGAACCCACGCCGATTGAGCAGGGATTAAAACGTACCAGTCTTACTCTTGCCGATATTCAGGATGCCGAAGCAC
GTTTAACACGATTTGCACCTTATCTGGAAAAAGTATTTCCTGAACTGAGAAGTACACAGGGCAAAATTGAGTCTGAGATT
GTATCTATCCCAACAATGCAACATGACTGTAGCAAACGCTTTGCAATCGAACCAAATGGAACATGGTGGCTGAAAAAAGA
TAGTCATTTACCTATTTCTGGTTCAATTAAGGCGCGTGGTGGAATCTATGAGGTACTGGCTCATGCTGAAAAGTTGGCAC
TTAAAGCGGGTTTAGTTACATTGCAAGATAACTATTCACAACTCGATAGTGATCAGGCACGTCAATTTTTCTCAAATTAT
CAAATTGCAGTAGGATCAACTGGAAATTTGGGGTTATCGATTGGAATTATGAGTGCCAAACTAGGCTTTCGAGTGAGTGT
GCATATGTCAGCAGATGCACGTCAGTGGAAAAAAGACAAGCTACGTTCACTGGGTGTCAATGTGGTTGAATATGCCAGTG
ATTATGGTGTTGCAGTAGAGCAGGGACGCAAAGCTGCAGAGTCAGATCCAAACTGCTTTTTCATTGATGATGAGAACTCG
ACCACTTTATTTTTAGGCTATGCTGTTGCTGGCTTACGTTTAAAACAGCAATTAATCGATCAGAATATTCAAGTTGATGC
TGAGCATCCTTTATTTGTTTATTTACCTTGTGGAGTAGGCGGTGGCCCTGGTGGTGTGAGTTTTGGACTTAAACATGCCC
TTGGTGAGCATGTACACTGTATTTTTGCCGAACCGACTCACTCACCTTGCATGCTGCTCGGGGTTTATACGGGTTTACAT
GATCAGATTTGTGTAGCAGATATTGGATTGGATAATGCTACCGCTGCCGATGGGCTTGCGGTGGGACGTGCTTCAGGTTT
TGTTGGACGGGCTATGCAAGATCTGATTGATGGTTACTACACTATTTCAGATCAACACTTATTTGAGTTTATTCGCTTAA
TGGATCAAACCCAATCCATCCAACTTGAACCTTCTGCTGTGGCAGGGGTGTTGGGCATTTATCATGTCAATACAAATAAA
TCCTATCAACAGGCTTATCATTTAAATGCGATACAACTAAAAAATGCAACACATTTAATTTGGGCAACGGGTGGCGGTAT
GGTTCCGCCCAATGAAATGCAAAAATATTTAAAGCAGTGTGAATAA

Upstream 100 bases:

>100_bases
GGCCTTTTTTTTATCTCTGGTTTATTTTAACGGTTTATTATTTATTTTGTATTTGGGCTGTGCATGATTTTTGCCCTGTA
TTAAAGGTTTTTATCTATTT

Downstream 100 bases:

>100_bases
TAAAAAGCCTGTGTAGCATACAGGCTTCTTAAAACTTATTTCTTAAACAGCGATGATAACTTCTCAAGAGGTAACTTGTC
TGTTGCAAATCCATAGAGTG

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTTLNIQAIQQDSLIKSLKNYEEIFWFQPEPTPIEQGLKRTSLTLADIQDAEARLTRFAPYLEKVFPELRSTQGKIESEI
VSIPTMQHDCSKRFAIEPNGTWWLKKDSHLPISGSIKARGGIYEVLAHAEKLALKAGLVTLQDNYSQLDSDQARQFFSNY
QIAVGSTGNLGLSIGIMSAKLGFRVSVHMSADARQWKKDKLRSLGVNVVEYASDYGVAVEQGRKAAESDPNCFFIDDENS
TTLFLGYAVAGLRLKQQLIDQNIQVDAEHPLFVYLPCGVGGGPGGVSFGLKHALGEHVHCIFAEPTHSPCMLLGVYTGLH
DQICVADIGLDNATAADGLAVGRASGFVGRAMQDLIDGYYTISDQHLFEFIRLMDQTQSIQLEPSAVAGVLGIYHVNTNK
SYQQAYHLNAIQLKNATHLIWATGGGMVPPNEMQKYLKQCE

Sequences:

>Translated_441_residues
MTTLNIQAIQQDSLIKSLKNYEEIFWFQPEPTPIEQGLKRTSLTLADIQDAEARLTRFAPYLEKVFPELRSTQGKIESEI
VSIPTMQHDCSKRFAIEPNGTWWLKKDSHLPISGSIKARGGIYEVLAHAEKLALKAGLVTLQDNYSQLDSDQARQFFSNY
QIAVGSTGNLGLSIGIMSAKLGFRVSVHMSADARQWKKDKLRSLGVNVVEYASDYGVAVEQGRKAAESDPNCFFIDDENS
TTLFLGYAVAGLRLKQQLIDQNIQVDAEHPLFVYLPCGVGGGPGGVSFGLKHALGEHVHCIFAEPTHSPCMLLGVYTGLH
DQICVADIGLDNATAADGLAVGRASGFVGRAMQDLIDGYYTISDQHLFEFIRLMDQTQSIQLEPSAVAGVLGIYHVNTNK
SYQQAYHLNAIQLKNATHLIWATGGGMVPPNEMQKYLKQCE
>Mature_440_residues
TTLNIQAIQQDSLIKSLKNYEEIFWFQPEPTPIEQGLKRTSLTLADIQDAEARLTRFAPYLEKVFPELRSTQGKIESEIV
SIPTMQHDCSKRFAIEPNGTWWLKKDSHLPISGSIKARGGIYEVLAHAEKLALKAGLVTLQDNYSQLDSDQARQFFSNYQ
IAVGSTGNLGLSIGIMSAKLGFRVSVHMSADARQWKKDKLRSLGVNVVEYASDYGVAVEQGRKAAESDPNCFFIDDENST
TLFLGYAVAGLRLKQQLIDQNIQVDAEHPLFVYLPCGVGGGPGGVSFGLKHALGEHVHCIFAEPTHSPCMLLGVYTGLHD
QICVADIGLDNATAADGLAVGRASGFVGRAMQDLIDGYYTISDQHLFEFIRLMDQTQSIQLEPSAVAGVLGIYHVNTNKS
YQQAYHLNAIQLKNATHLIWATGGGMVPPNEMQKYLKQCE

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=431, Percent_Identity=67.2853828306264, Blast_Score=571, Evalue=1e-164,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_ACIAD (Q6FDC1)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045759.1
- ProteinModelPortal:   Q6FDC1
- STRING:   Q6FDC1
- GeneID:   2879768
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1048
- NMPDR:   fig|62977.3.peg.1144
- eggNOG:   COG3048
- HOGENOM:   HBG288722
- OMA:   WKKDLLR
- PhylomeDB:   Q6FDC1
- ProtClustDB:   PRK02991
- BioCyc:   ASP62977:ACIAD1048-MONOMER
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 48569; Mature: 48438

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLNIQAIQQDSLIKSLKNYEEIFWFQPEPTPIEQGLKRTSLTLADIQDAEARLTRFAP
CCEEEEEEHHHHHHHHHHHCHHHEEEECCCCCHHHHCHHHHCEEEECCCHHHHHHHHHHH
YLEKVFPELRSTQGKIESEIVSIPTMQHDCSKRFAIEPNGTWWLKKDSHLPISGSIKARG
HHHHHHHHHHHHCCCHHHHHEECCCCHHCCCCCEEECCCCEEEEECCCCCCCCCCCCCCC
GIYEVLAHAEKLALKAGLVTLQDNYSQLDSDQARQFFSNYQIAVGSTGNLGLSIGIMSAK
CHHHHHHHHHHHHHHHCEEEEECCHHHCCHHHHHHHHCCCEEEEECCCCCEEEEEEEEEC
LGFRVSVHMSADARQWKKDKLRSLGVNVVEYASDYGVAVEQGRKAAESDPNCFFIDDENS
CCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCCCCCCCCEEEEECCCC
TTLFLGYAVAGLRLKQQLIDQNIQVDAEHPLFVYLPCGVGGGPGGVSFGLKHALGEHVHC
CEEEEEHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEE
IFAEPTHSPCMLLGVYTGLHDQICVADIGLDNATAADGLAVGRASGFVGRAMQDLIDGYY
EEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHCCEE
TISDQHLFEFIRLMDQTQSIQLEPSAVAGVLGIYHVNTNKSYQQAYHLNAIQLKNATHLI
EECHHHHHHHHHHHCCCCCEEECHHHHEEEEEEEEECCCCCHHHHHCCCEEEECCCEEEE
WATGGGMVPPNEMQKYLKQCE
EECCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TTLNIQAIQQDSLIKSLKNYEEIFWFQPEPTPIEQGLKRTSLTLADIQDAEARLTRFAP
CEEEEEEHHHHHHHHHHHCHHHEEEECCCCCHHHHCHHHHCEEEECCCHHHHHHHHHHH
YLEKVFPELRSTQGKIESEIVSIPTMQHDCSKRFAIEPNGTWWLKKDSHLPISGSIKARG
HHHHHHHHHHHHCCCHHHHHEECCCCHHCCCCCEEECCCCEEEEECCCCCCCCCCCCCCC
GIYEVLAHAEKLALKAGLVTLQDNYSQLDSDQARQFFSNYQIAVGSTGNLGLSIGIMSAK
CHHHHHHHHHHHHHHHCEEEEECCHHHCCHHHHHHHHCCCEEEEECCCCCEEEEEEEEEC
LGFRVSVHMSADARQWKKDKLRSLGVNVVEYASDYGVAVEQGRKAAESDPNCFFIDDENS
CCEEEEEEECCCHHHHHHHHHHHHCCHHHHHHCCCCHHHHHCCCCCCCCCCEEEEECCCC
TTLFLGYAVAGLRLKQQLIDQNIQVDAEHPLFVYLPCGVGGGPGGVSFGLKHALGEHVHC
CEEEEEHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEE
IFAEPTHSPCMLLGVYTGLHDQICVADIGLDNATAADGLAVGRASGFVGRAMQDLIDGYY
EEECCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCEECCCCCHHHHHHHHHHCCEE
TISDQHLFEFIRLMDQTQSIQLEPSAVAGVLGIYHVNTNKSYQQAYHLNAIQLKNATHLI
EECHHHHHHHHHHHCCCCCEEECHHHHEEEEEEEEECCCCCHHHHHCCCEEEECCCEEEE
WATGGGMVPPNEMQKYLKQCE
EECCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA