Click here to switch to the map view.

The map label for this gene is vdlD [H]

Identifier: 50084225

GI number: 50084225

Start: 1015324

End: 1015845

Strand: Direct

Name: vdlD [H]

Synonym: ACIAD1023

Alternate gene names: 50084225

Gene position: 1015324-1015845 (Clockwise)

Preceding gene: 50084224

Following gene: 50084227

Centisome position: 28.21

GC content: 40.42

Gene sequence:

>522_bases
ATGTCTCCATTAGATCAAGTTACACAAGCTTCAGAAGATCAATCCGAACTTACAATGTCTGTTTTAATGACGCCTGATAT
GGCAAATTTTTCAGGAAATGTTCATGGTGGTACGATTTTAAAGCTGCTTGATCAGGTCGCATATGCATGTGCGAGCCGTT
ATTCAGGAAGTTACGTGGTGACGCTTTCCGTCGATAAAGTGACTTTTAAAGAGCCAATCTATGTAGGCGAACTAGTGACA
TTTTTAGCGAGTGTTAATCATGTCGGACGGACTTCAATGGAAATAGGAATCCGTGTTGAAGCTCAAAATATTCGAAGCAG
GACTGTACGACACACCAATAGTTGCTATTTCACGATGGTCGCTGTTGATGAAACGGGAAAACCACAAAAAGTACCTGAAC
TGAAATTAGATACAGAATGGAAAATTTGTCGTTTTGAAGCTGCCGAGCTACGTAAACAACGCCGTTTACAAGACAATTCT
AATCCTTCGTGTAGCTTGTTTAAGAAAAATACAGACGGCTGA

Upstream 100 bases:

>100_bases
ATGATTCTGCTTGAATATTTGCCGCTTTTAGCATGTTTTTCAACGTTGAAATATCTCATAATAAACGGTGTAAATTCTTC
CCGTGTAGAGTGAAAAAGAT

Downstream 100 bases:

>100_bases
TGAGTGTCTGAAATAGCAAAAGTAAATTTGACTGTATTTAAATCATAAAAGCCTAAAATAAAAGGGCAAAACCGCAGCAA
TGGTTTAGCCCTTTTACTAG

Product: acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSPLDQVTQASEDQSELTMSVLMTPDMANFSGNVHGGTILKLLDQVAYACASRYSGSYVVTLSVDKVTFKEPIYVGELVT
FLASVNHVGRTSMEIGIRVEAQNIRSRTVRHTNSCYFTMVAVDETGKPQKVPELKLDTEWKICRFEAAELRKQRRLQDNS
NPSCSLFKKNTDG

Sequences:

>Translated_173_residues
MSPLDQVTQASEDQSELTMSVLMTPDMANFSGNVHGGTILKLLDQVAYACASRYSGSYVVTLSVDKVTFKEPIYVGELVT
FLASVNHVGRTSMEIGIRVEAQNIRSRTVRHTNSCYFTMVAVDETGKPQKVPELKLDTEWKICRFEAAELRKQRRLQDNS
NPSCSLFKKNTDG
>Mature_172_residues
SPLDQVTQASEDQSELTMSVLMTPDMANFSGNVHGGTILKLLDQVAYACASRYSGSYVVTLSVDKVTFKEPIYVGELVTF
LASVNHVGRTSMEIGIRVEAQNIRSRTVRHTNSCYFTMVAVDETGKPQKVPELKLDTEWKICRFEAAELRKQRRLQDNSN
PSCSLFKKNTDG

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI22165400, Length=144, Percent_Identity=32.6388888888889, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI22165355, Length=144, Percent_Identity=32.6388888888889, Blast_Score=76, Evalue=1e-14,
Organism=Homo sapiens, GI32528284, Length=153, Percent_Identity=30.718954248366, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI32528286, Length=153, Percent_Identity=30.718954248366, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI75709208, Length=153, Percent_Identity=30.718954248366, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI32528282, Length=153, Percent_Identity=30.718954248366, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI18640736, Length=138, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1787506, Length=122, Percent_Identity=30.327868852459, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 19316; Mature: 19185

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLDQVTQASEDQSELTMSVLMTPDMANFSGNVHGGTILKLLDQVAYACASRYSGSYVV
CCCHHHHHHCCCCHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
TLSVDKVTFKEPIYVGELVTFLASVNHVGRTSMEIGIRVEAQNIRSRTVRHTNSCYFTMV
EEEECCEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHEECCCEEEEEE
AVDETGKPQKVPELKLDTEWKICRFEAAELRKQRRLQDNSNPSCSLFKKNTDG
EEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
SPLDQVTQASEDQSELTMSVLMTPDMANFSGNVHGGTILKLLDQVAYACASRYSGSYVV
CCHHHHHHCCCCHHHEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEE
TLSVDKVTFKEPIYVGELVTFLASVNHVGRTSMEIGIRVEAQNIRSRTVRHTNSCYFTMV
EEEECCEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHEECCCEEEEEE
AVDETGKPQKVPELKLDTEWKICRFEAAELRKQRRLQDNSNPSCSLFKKNTDG
EEECCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]