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The map label for this gene is yeiR [H]

Identifier: 50084227

GI number: 50084227

Start: 1016717

End: 1017733

Strand: Direct

Name: yeiR [H]

Synonym: ACIAD1025

Alternate gene names: 50084227

Gene position: 1016717-1017733 (Clockwise)

Preceding gene: 50084225

Following gene: 50084229

Centisome position: 28.25

GC content: 41.2

Gene sequence:

>1017_bases
TTGCATGTGAAACTGCTCATTCCTCAGACTGTTCCCACACATATTATTTCTGGATTTCTAGGCGCAGGTAAAACGACGCT
GCTACAGCACTTACTGAGTCAGAAGCCAGAAAATGAAGTCTGGGCTGTACTGATGAATGAGTTTGGCCAGATTGGTATCG
ATCAGCAACTTTTACCTCAGCAACAAGGTTATCAAGTCAAGGAATTGTTGGGCGGTTGTTTATGCTGTAGCAGTCAACTG
CCTTTACATATTGCATTGGCCCGATTACTTACCGAGACTCAACCAGATCGACTTTTTATTGAACCTACAGGTTTAGGGCA
TCCTGCCCAATTGGTGGAGCAACTGACTGAACCTCATTGGCAAAGTAGTTTGAATATGCGTGCATTGATTACTGTGCTGG
ATGGGAGCCGTTTGCATGAAGAGGCATGGGTTCAGCAAAACTTATATGAAGATCAGTTAAAAGCAGCACAGATAGTGGTG
GTGTCGCATGGTGATCAAATGAGTGGTACAGATGAAAAGGCGTTAGAAAAATTACAGGAAGAATATCAAGCCTATTCACA
ATCTTGGTTTAAAACGGCAAATGGTGAATTAGCCTTAGACGCTATTGATCATCCTCATCTTGTCACCTCTAGAATCTTAC
AGCCGTTACTTATGCAACAGAAAACATTCGTTTCAGCACAAGAACCAATACCAGAGATCAAACAGCTTCCATATCACTAT
GTTGAAAGTTCGCAAGGTTATCATGTAGCAGGCTGGAAAATGCCACGTCGCTGGATTTTTGATTTTGACTCGTTATTTGA
GTTGTTATGCAATCAATCCAACTGGCTCAGAATCAAAGCGATTTTTAATACCAGTCAGGGCTGGATGATATTTAATTTTA
ATCCCGAACAGTTTAATTACAAAACAGGACAGGCCAATACGGATAGTCGAATTGAAATTATTACAAGCCAGTTAGGCAAC
TGGCTTGATTTTGAGAAACAGTTAATGGCATGTCGGCTAGATGAGCAGAATACTTAA

Upstream 100 bases:

>100_bases
TCACAGAATCGAAAAAATTCATGTCTAAGGAATTCTTGCATTAATTCAGCTCGAATTTAAGAGATACTTAGGTAAAATCA
TTATTTTTATTGCCTATGGA

Downstream 100 bases:

>100_bases
GTGTTTAGTTGACTGATGATTTATGCTCAAGTACGGCACGTGCTTGGGCATGGTCAATGTCCTTTTCCCAATGTGCAATC
ACTACCGTGGCAACACAATT

Product: cobalamin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MHVKLLIPQTVPTHIISGFLGAGKTTLLQHLLSQKPENEVWAVLMNEFGQIGIDQQLLPQQQGYQVKELLGGCLCCSSQL
PLHIALARLLTETQPDRLFIEPTGLGHPAQLVEQLTEPHWQSSLNMRALITVLDGSRLHEEAWVQQNLYEDQLKAAQIVV
VSHGDQMSGTDEKALEKLQEEYQAYSQSWFKTANGELALDAIDHPHLVTSRILQPLLMQQKTFVSAQEPIPEIKQLPYHY
VESSQGYHVAGWKMPRRWIFDFDSLFELLCNQSNWLRIKAIFNTSQGWMIFNFNPEQFNYKTGQANTDSRIEIITSQLGN
WLDFEKQLMACRLDEQNT

Sequences:

>Translated_338_residues
MHVKLLIPQTVPTHIISGFLGAGKTTLLQHLLSQKPENEVWAVLMNEFGQIGIDQQLLPQQQGYQVKELLGGCLCCSSQL
PLHIALARLLTETQPDRLFIEPTGLGHPAQLVEQLTEPHWQSSLNMRALITVLDGSRLHEEAWVQQNLYEDQLKAAQIVV
VSHGDQMSGTDEKALEKLQEEYQAYSQSWFKTANGELALDAIDHPHLVTSRILQPLLMQQKTFVSAQEPIPEIKQLPYHY
VESSQGYHVAGWKMPRRWIFDFDSLFELLCNQSNWLRIKAIFNTSQGWMIFNFNPEQFNYKTGQANTDSRIEIITSQLGN
WLDFEKQLMACRLDEQNT
>Mature_338_residues
MHVKLLIPQTVPTHIISGFLGAGKTTLLQHLLSQKPENEVWAVLMNEFGQIGIDQQLLPQQQGYQVKELLGGCLCCSSQL
PLHIALARLLTETQPDRLFIEPTGLGHPAQLVEQLTEPHWQSSLNMRALITVLDGSRLHEEAWVQQNLYEDQLKAAQIVV
VSHGDQMSGTDEKALEKLQEEYQAYSQSWFKTANGELALDAIDHPHLVTSRILQPLLMQQKTFVSAQEPIPEIKQLPYHY
VESSQGYHVAGWKMPRRWIFDFDSLFELLCNQSNWLRIKAIFNTSQGWMIFNFNPEQFNYKTGQANTDSRIEIITSQLGN
WLDFEKQLMACRLDEQNT

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=130, Percent_Identity=33.8461538461538, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI223941779, Length=130, Percent_Identity=33.8461538461538, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI33469141, Length=130, Percent_Identity=33.8461538461538, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI148727351, Length=130, Percent_Identity=33.0769230769231, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI146231952, Length=130, Percent_Identity=33.0769230769231, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1788499, Length=330, Percent_Identity=34.2424242424242, Blast_Score=184, Evalue=5e-48,
Organism=Escherichia coli, GI87082430, Length=175, Percent_Identity=31.4285714285714, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 38678; Mature: 38678

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVKLLIPQTVPTHIISGFLGAGKTTLLQHLLSQKPENEVWAVLMNEFGQIGIDQQLLPQ
CEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHCCC
QQGYQVKELLGGCLCCSSQLPLHIALARLLTETQPDRLFIEPTGLGHPAQLVEQLTEPHW
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCHH
QSSLNMRALITVLDGSRLHEEAWVQQNLYEDQLKAAQIVVVSHGDQMSGTDEKALEKLQE
HHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHH
EYQAYSQSWFKTANGELALDAIDHPHLVTSRILQPLLMQQKTFVSAQEPIPEIKQLPYHY
HHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHH
VESSQGYHVAGWKMPRRWIFDFDSLFELLCNQSNWLRIKAIFNTSQGWMIFNFNPEQFNY
HCCCCCEEEECCCCCHHHHCCHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECHHHCCE
KTGQANTDSRIEIITSQLGNWLDFEKQLMACRLDEQNT
ECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHVKLLIPQTVPTHIISGFLGAGKTTLLQHLLSQKPENEVWAVLMNEFGQIGIDQQLLPQ
CEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHCCC
QQGYQVKELLGGCLCCSSQLPLHIALARLLTETQPDRLFIEPTGLGHPAQLVEQLTEPHW
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCHH
QSSLNMRALITVLDGSRLHEEAWVQQNLYEDQLKAAQIVVVSHGDQMSGTDEKALEKLQE
HHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHH
EYQAYSQSWFKTANGELALDAIDHPHLVTSRILQPLLMQQKTFVSAQEPIPEIKQLPYHY
HHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHH
VESSQGYHVAGWKMPRRWIFDFDSLFELLCNQSNWLRIKAIFNTSQGWMIFNFNPEQFNY
HCCCCCEEEECCCCCHHHHCCHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECHHHCCE
KTGQANTDSRIEIITSQLGNWLDFEKQLMACRLDEQNT
ECCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]