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The map label for this gene is gudP [H]

Identifier: 50084196

GI number: 50084196

Start: 978348

End: 979577

Strand: Direct

Name: gudP [H]

Synonym: ACIAD0992

Alternate gene names: 50084196

Gene position: 978348-979577 (Clockwise)

Preceding gene: 50084195

Following gene: 50084197

Centisome position: 27.19

GC content: 43.01

Gene sequence:

>1230_bases
ATGTTAAATGATATAGATGAAAAAAAAGGATTCAAACACTGGATACCCGCCTTTGTCTTAATGGCATGTGTGGTATTGGC
CTTCTTTGACAAGATTAGTATTGCAGTGTTGTTTTCAGATCCGCATTTTCAGGACGCAATGGGAATTGCTGAGGACAAAG
CCAAACTGGGGTGGCTAATGACCAGCTTTTTGCTGGCGTATGGATTCTCTTCTATTTTTCTGAGCTTTCTGGGCGACATT
TTTAATCCCAAGAAAATGCTGTTTTGGAGTGTAACCTCGTGGGGTATTTTAATGCTGATCATGGGATTTACCACACACTA
TGGCAGCATGTTGTTTTTGCGGGTATTGCTTGGTATTGCAGAAGGCCCTCTGTTTGCGCTGGCTTATGCCATTGTCAAAC
AAACTTATACAGATCGTCAGCAAGCACGTGCATCAACCATGTTTTTACTTGGTACACCCATTGGCGCATTTTTAGGCTTT
CCAATTACTGCGGCGGTGCTGGCTAAGCACGACTGGCATACCACGTTCTTTGTCATGGCGGCTTTAACTTTAGTGGTGAT
GATCATTATTGTACTTGGATTGCGCAATTTACAGTTACGTAAAATCATTGAAATTGAAGACTCAAGCAAGCGTGTCAATT
TTAAGGGACATATTGCCAATACCAAACTTTTACTTAAAAACAGGGCGTTCTGGCTGGTCTGTTTATTCAATATCGCACTC
ATGACTTACTTATGGGGTCTGAATAGTTGGGTGCCGTCTTACTTGATTCAAGATAAAGGTTTTAACCTCAAAGAGTTCGG
TTTTTATTCGAGCTTGCCATTCATTGCCATGTTGGTGGGTGAAGTCGTAGGTGCTGTTTTTTCAGACAAATTGGGTAAAC
GTGCGATTCAGGTTTTTAGTGGTCTATTGGTCGCAGGAATCTCGCTTTACGTGATGGTCTTAATGACAGATCCACTTCTT
ATTATTGCAGCAATGTCATTAAGTTCAATGGCATGGGGTTTTGGGGTTGCAGCCGTATTCGCTTTGCTCGCACGTGTCAC
AACAGCAGATGTCGGAGCGACAGCAGGCGGAATTTTCAACGGTTTAGCGAACTTTGCCAGTGCAGCAGCGCCTGTACTGA
TTGGCATGATCGTCATGCAAACTGGCAGTTTTAATTTGGGAATCACATTCTTGGCAGTGGTGGCCATTGTGGGTTCCTTC
TTCCTTACACCATTACTCAAACGTTACTAA

Upstream 100 bases:

>100_bases
TCCTGAATTTAATGTCATGAAGCTCAAACCGTAAGCGCACTTCACGACATCCAGTCAGAGCACTCATTTTAGGCGAATCG
CCAGATCGAAGGAATGTTGC

Downstream 100 bases:

>100_bases
TTCAGTTCAATTTCTTAGCAGGAGTAAGACATGAGCACTCAACAATTTGAATCATGGACGCAACCCGAAGACAAAAGTTT
AGAAGAATGGTTAAACACGC

Product: major facilitator superfamily permease

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MLNDIDEKKGFKHWIPAFVLMACVVLAFFDKISIAVLFSDPHFQDAMGIAEDKAKLGWLMTSFLLAYGFSSIFLSFLGDI
FNPKKMLFWSVTSWGILMLIMGFTTHYGSMLFLRVLLGIAEGPLFALAYAIVKQTYTDRQQARASTMFLLGTPIGAFLGF
PITAAVLAKHDWHTTFFVMAALTLVVMIIIVLGLRNLQLRKIIEIEDSSKRVNFKGHIANTKLLLKNRAFWLVCLFNIAL
MTYLWGLNSWVPSYLIQDKGFNLKEFGFYSSLPFIAMLVGEVVGAVFSDKLGKRAIQVFSGLLVAGISLYVMVLMTDPLL
IIAAMSLSSMAWGFGVAAVFALLARVTTADVGATAGGIFNGLANFASAAAPVLIGMIVMQTGSFNLGITFLAVVAIVGSF
FLTPLLKRY

Sequences:

>Translated_409_residues
MLNDIDEKKGFKHWIPAFVLMACVVLAFFDKISIAVLFSDPHFQDAMGIAEDKAKLGWLMTSFLLAYGFSSIFLSFLGDI
FNPKKMLFWSVTSWGILMLIMGFTTHYGSMLFLRVLLGIAEGPLFALAYAIVKQTYTDRQQARASTMFLLGTPIGAFLGF
PITAAVLAKHDWHTTFFVMAALTLVVMIIIVLGLRNLQLRKIIEIEDSSKRVNFKGHIANTKLLLKNRAFWLVCLFNIAL
MTYLWGLNSWVPSYLIQDKGFNLKEFGFYSSLPFIAMLVGEVVGAVFSDKLGKRAIQVFSGLLVAGISLYVMVLMTDPLL
IIAAMSLSSMAWGFGVAAVFALLARVTTADVGATAGGIFNGLANFASAAAPVLIGMIVMQTGSFNLGITFLAVVAIVGSF
FLTPLLKRY
>Mature_409_residues
MLNDIDEKKGFKHWIPAFVLMACVVLAFFDKISIAVLFSDPHFQDAMGIAEDKAKLGWLMTSFLLAYGFSSIFLSFLGDI
FNPKKMLFWSVTSWGILMLIMGFTTHYGSMLFLRVLLGIAEGPLFALAYAIVKQTYTDRQQARASTMFLLGTPIGAFLGF
PITAAVLAKHDWHTTFFVMAALTLVVMIIIVLGLRNLQLRKIIEIEDSSKRVNFKGHIANTKLLLKNRAFWLVCLFNIAL
MTYLWGLNSWVPSYLIQDKGFNLKEFGFYSSLPFIAMLVGEVVGAVFSDKLGKRAIQVFSGLLVAGISLYVMVLMTDPLL
IIAAMSLSSMAWGFGVAAVFALLARVTTADVGATAGGIFNGLANFASAAAPVLIGMIVMQTGSFNLGITFLAVVAIVGSF
FLTPLLKRY

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI1789152, Length=430, Percent_Identity=24.6511627906977, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1789515, Length=445, Percent_Identity=24.4943820224719, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87082320, Length=415, Percent_Identity=22.6506024096386, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI2367379, Length=389, Percent_Identity=21.3367609254499, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082071, Length=417, Percent_Identity=23.021582733813, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI2367193, Length=424, Percent_Identity=19.5754716981132, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44900; Mature: 44900

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNDIDEKKGFKHWIPAFVLMACVVLAFFDKISIAVLFSDPHFQDAMGIAEDKAKLGWLM
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHCCHHHHHHHHHHH
TSFLLAYGFSSIFLSFLGDIFNPKKMLFWSVTSWGILMLIMGFTTHYGSMLFLRVLLGIA
HHHHHHHHHHHHHHHHHHHHCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EGPLFALAYAIVKQTYTDRQQARASTMFLLGTPIGAFLGFPITAAVLAKHDWHTTFFVMA
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
ALTLVVMIIIVLGLRNLQLRKIIEIEDSSKRVNFKGHIANTKLLLKNRAFWLVCLFNIAL
HHHHHHHHHHHHCCCCCHHHHHEEECCCCCEECEEEEECCCEEHHHCCHHHHHHHHHHHH
MTYLWGLNSWVPSYLIQDKGFNLKEFGFYSSLPFIAMLVGEVVGAVFSDKLGKRAIQVFS
HHHHHHHHHHHHHHHHHCCCCCHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLVAGISLYVMVLMTDPLLIIAAMSLSSMAWGFGVAAVFALLARVTTADVGATAGGIFN
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GLANFASAAAPVLIGMIVMQTGSFNLGITFLAVVAIVGSFFLTPLLKRY
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNDIDEKKGFKHWIPAFVLMACVVLAFFDKISIAVLFSDPHFQDAMGIAEDKAKLGWLM
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHCCHHHHHHHHHHH
TSFLLAYGFSSIFLSFLGDIFNPKKMLFWSVTSWGILMLIMGFTTHYGSMLFLRVLLGIA
HHHHHHHHHHHHHHHHHHHHCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EGPLFALAYAIVKQTYTDRQQARASTMFLLGTPIGAFLGFPITAAVLAKHDWHTTFFVMA
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
ALTLVVMIIIVLGLRNLQLRKIIEIEDSSKRVNFKGHIANTKLLLKNRAFWLVCLFNIAL
HHHHHHHHHHHHCCCCCHHHHHEEECCCCCEECEEEEECCCEEHHHCCHHHHHHHHHHHH
MTYLWGLNSWVPSYLIQDKGFNLKEFGFYSSLPFIAMLVGEVVGAVFSDKLGKRAIQVFS
HHHHHHHHHHHHHHHHHCCCCCHHHCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLVAGISLYVMVLMTDPLLIIAAMSLSSMAWGFGVAAVFALLARVTTADVGATAGGIFN
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GLANFASAAAPVLIGMIVMQTGSFNLGITFLAVVAIVGSFFLTPLLKRY
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]