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The map label for this gene is oprD [H]

Identifier: 50084187

GI number: 50084187

Start: 969761

End: 971044

Strand: Direct

Name: oprD [H]

Synonym: ACIAD0983

Alternate gene names: 50084187

Gene position: 969761-971044 (Clockwise)

Preceding gene: 50084186

Following gene: 50084190

Centisome position: 26.95

GC content: 39.72

Gene sequence:

>1284_bases
ATGAAAAAGACATCCTTATGGGTGGGGGGCTGCTTATGCCTATTATTTACCCCTGTAGTCCATGCCGAATTTATTGCAGA
CAGTAAAGCAGAACTCACACTTCGAAACTTTTATTTTGATCGGGATTATAAACAAGATCCGTACCCCTATACCGCCGCCC
GAGATTGGGCGCAAGGGGTAATTTTTAAAGGTCAGTCTGGTTATACAGATGGACCAGTGGGTTTTGGTGTTGATGTACTG
GCGATGGCTGGATTCAATTTGATGGGAAATCGTGCTGATGATTATGCACGTAGTGGTTTGTTGCCTGTCAATTCAGATAA
TTCACGTGATGATTATTATGGCAAAGTCGGAATAACAGGCAAGGCAAAGTATCGCAACAATGAGCTGTTTGTGGGTGATT
TGGTGCCGTTACTGCCTACTATTTTCTCTTCACCTGCGCGCTTGTTTCCACAAACTTATCGAGGAGTACGTTTTTTATCG
ACAGAAATTCCAAAATTTCAACTGGAAGGTTTTTATGTCGATGAAGTGCGTCAGCGTGATTCCATCCGTTTTACCGATGT
TGGAACAGACAATATCAATCGTCGTTTTGATCGCGCTGCAACGACAGATTATTTCTATACCTTGGGTGGCGCATATCAGG
TTAATGATGCGTATAGAGTACGAGCTTATCAGGCAGAATTGCATAATATTTACCAACAACAATTTTTGGGCTTTAACGGC
AAACAACCGCTGAATCAACAATTAAATTTTTTGAGTGATGTTCGGTTTTTCAATAGCGAAGATGCGGGTACAAAGAAAAT
TGGAGAGGTAGATAACCGTCATTTAAGTGGTTTATTTGGCCTCAATTATCAAAATCATACGATCTCTTTAGGTTATATGC
AGTCATTTGGTGCTACAGGTTTACCATTTTTGTCTGGTACAGAAAGCCCGGTTGTATTGGATTTTATGAGTTCGGATTAT
TCTAACAAAGATGAAAAAGTATATTCCGTCCGTTATGAATACGAGTTTAAAAATGTAAATGTGGGGGATATTTCTCTGAA
TGGGTTACGCTTTATGACCCGTTATGCCAAAGGTGAAGACATTAATTTACTCAATTATGGCGACCAGCGTTTCAAAGAAG
AATCGATGGAAGTTGAGTTGGGATATCGTATTCCCGAAGGTAAGTTCAAAGGCTTAGGATTACGTGGGCGCTTTTCTCAC
TACCGTAATGATATGCCAACGATTATGACTTTTCATTCAACCAACGAAACACGTTTAAATGTAGATTATACTTTTAAGTT
TTAA

Upstream 100 bases:

>100_bases
CTGAGCTTGAGTAAGGCATTTTATCGCCAGAAAGAAGGTCTAGGAAGTTCTATAAAAACAGTTGCTTAAATCAATATAAT
AAAACAGTAGAGTTTAAAAA

Downstream 100 bases:

>100_bases
ACCCACTATTTGTATACATTTAAAATGCTATAAAGATTAAGTCATGTTAAAGCATGGCTTAATCTTTAGTTTTTTACTTA
AACGGCATGGTTTTAGCTCT

Product: porin

Products: NA

Alternate protein names: Imipenem/basic amino acid-specific outer membrane pore; Outer membrane protein D2 [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MKKTSLWVGGCLCLLFTPVVHAEFIADSKAELTLRNFYFDRDYKQDPYPYTAARDWAQGVIFKGQSGYTDGPVGFGVDVL
AMAGFNLMGNRADDYARSGLLPVNSDNSRDDYYGKVGITGKAKYRNNELFVGDLVPLLPTIFSSPARLFPQTYRGVRFLS
TEIPKFQLEGFYVDEVRQRDSIRFTDVGTDNINRRFDRAATTDYFYTLGGAYQVNDAYRVRAYQAELHNIYQQQFLGFNG
KQPLNQQLNFLSDVRFFNSEDAGTKKIGEVDNRHLSGLFGLNYQNHTISLGYMQSFGATGLPFLSGTESPVVLDFMSSDY
SNKDEKVYSVRYEYEFKNVNVGDISLNGLRFMTRYAKGEDINLLNYGDQRFKEESMEVELGYRIPEGKFKGLGLRGRFSH
YRNDMPTIMTFHSTNETRLNVDYTFKF

Sequences:

>Translated_427_residues
MKKTSLWVGGCLCLLFTPVVHAEFIADSKAELTLRNFYFDRDYKQDPYPYTAARDWAQGVIFKGQSGYTDGPVGFGVDVL
AMAGFNLMGNRADDYARSGLLPVNSDNSRDDYYGKVGITGKAKYRNNELFVGDLVPLLPTIFSSPARLFPQTYRGVRFLS
TEIPKFQLEGFYVDEVRQRDSIRFTDVGTDNINRRFDRAATTDYFYTLGGAYQVNDAYRVRAYQAELHNIYQQQFLGFNG
KQPLNQQLNFLSDVRFFNSEDAGTKKIGEVDNRHLSGLFGLNYQNHTISLGYMQSFGATGLPFLSGTESPVVLDFMSSDY
SNKDEKVYSVRYEYEFKNVNVGDISLNGLRFMTRYAKGEDINLLNYGDQRFKEESMEVELGYRIPEGKFKGLGLRGRFSH
YRNDMPTIMTFHSTNETRLNVDYTFKF
>Mature_427_residues
MKKTSLWVGGCLCLLFTPVVHAEFIADSKAELTLRNFYFDRDYKQDPYPYTAARDWAQGVIFKGQSGYTDGPVGFGVDVL
AMAGFNLMGNRADDYARSGLLPVNSDNSRDDYYGKVGITGKAKYRNNELFVGDLVPLLPTIFSSPARLFPQTYRGVRFLS
TEIPKFQLEGFYVDEVRQRDSIRFTDVGTDNINRRFDRAATTDYFYTLGGAYQVNDAYRVRAYQAELHNIYQQQFLGFNG
KQPLNQQLNFLSDVRFFNSEDAGTKKIGEVDNRHLSGLFGLNYQNHTISLGYMQSFGATGLPFLSGTESPVVLDFMSSDY
SNKDEKVYSVRYEYEFKNVNVGDISLNGLRFMTRYAKGEDINLLNYGDQRFKEESMEVELGYRIPEGKFKGLGLRGRFSH
YRNDMPTIMTFHSTNETRLNVDYTFKF

Specific function: Porin with a specificity for basic amino acids. Also possesses serine protease activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oprD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005318 [H]

Pfam domain/function: PF03573 OprD [H]

EC number: NA

Molecular weight: Translated: 48867; Mature: 48867

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTSLWVGGCLCLLFTPVVHAEFIADSKAELTLRNFYFDRDYKQDPYPYTAARDWAQGV
CCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCE
IFKGQSGYTDGPVGFGVDVLAMAGFNLMGNRADDYARSGLLPVNSDNSRDDYYGKVGITG
EEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHCCCEECCCCCCCCCCEEEEECCC
KAKYRNNELFVGDLVPLLPTIFSSPARLFPQTYRGVRFLSTEIPKFQLEGFYVDEVRQRD
CCEECCCEEEEHHHHHHHHHHHCCCHHHCHHHHCCEEEEECCCCCEEECCEEHHHHHCCC
SIRFTDVGTDNINRRFDRAATTDYFYTLGGAYQVNDAYRVRAYQAELHNIYQQQFLGFNG
CEEEEECCCCCHHHHHHHHCCCCEEEECCCEEEECCCEEEHHHHHHHHHHHHHHHCCCCC
KQPLNQQLNFLSDVRFFNSEDAGTKKIGEVDNRHLSGLFGLNYQNHTISLGYMQSFGATG
CCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCEEEECCCCCCEEEEEEHHHCCCCC
LPFLSGTESPVVLDFMSSDYSNKDEKVYSVRYEYEFKNVNVGDISLNGLRFMTRYAKGED
CCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCEECCEEECCHHHHHHHCCCCC
INLLNYGDQRFKEESMEVELGYRIPEGKFKGLGLRGRFSHYRNDMPTIMTFHSTNETRLN
EEEECCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCCEEEE
VDYTFKF
EEEEEEC
>Mature Secondary Structure
MKKTSLWVGGCLCLLFTPVVHAEFIADSKAELTLRNFYFDRDYKQDPYPYTAARDWAQGV
CCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCE
IFKGQSGYTDGPVGFGVDVLAMAGFNLMGNRADDYARSGLLPVNSDNSRDDYYGKVGITG
EEECCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHCCCEECCCCCCCCCCEEEEECCC
KAKYRNNELFVGDLVPLLPTIFSSPARLFPQTYRGVRFLSTEIPKFQLEGFYVDEVRQRD
CCEECCCEEEEHHHHHHHHHHHCCCHHHCHHHHCCEEEEECCCCCEEECCEEHHHHHCCC
SIRFTDVGTDNINRRFDRAATTDYFYTLGGAYQVNDAYRVRAYQAELHNIYQQQFLGFNG
CEEEEECCCCCHHHHHHHHCCCCEEEECCCEEEECCCEEEHHHHHHHHHHHHHHHCCCCC
KQPLNQQLNFLSDVRFFNSEDAGTKKIGEVDNRHLSGLFGLNYQNHTISLGYMQSFGATG
CCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCEEEECCCCCCEEEEEEHHHCCCCC
LPFLSGTESPVVLDFMSSDYSNKDEKVYSVRYEYEFKNVNVGDISLNGLRFMTRYAKGED
CCCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCEECCEEECCHHHHHHHCCCCC
INLLNYGDQRFKEESMEVELGYRIPEGKFKGLGLRGRFSHYRNDMPTIMTFHSTNETRLN
EEEECCCHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCCEEEE
VDYTFKF
EEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339257; 1427017; 10984043; 8012497; 2118530; 8843159; 9636669 [H]